Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

Németh, Krisztián, Leelahavanichkul, Asada, Yuen, Peter S T, Mayer, Balázs, Parmelee, Alissa, Doi, Kent, Robey, Pamela G, Leelahavanichkul, Kantima +6 more·2009·Nature Medicine

DOI 10.1038/nm.1905

Cited by (1,003)

Items 201–300 of 1,003

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C. Manferdini, F. Paolella, E. Gabusi, L. Gambari, A. Piacentini, G. Filardo, S. Fleury-Cappellesso, A. Barbero, M. Murphy, G. Lisignoli · 2017 · Osteoarthritis and Cartilage
Prostaglandin E 2 constrains systemic inflammation through an innate lymphoid cell–IL-22 axis
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Mesenchymal Stromal Cells Induce Peculiar Alternatively Activated Macrophages Capable of Dampening Both Innate and Adaptive Immune Responses
Laura Chiossone, Romana Conte, Grazia Maria Spaggiari, Martina Serra, Cristina Romei, Francesca Bellora, Flavio Becchetti, A. Andaloro, Lorenzo Moretta, Cristina Bottino · 2016 · Stem Cells
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Undurti Narasimha Das · 2021 · Biomolecules
Immunomodulatory properties of human adult and fetal multipotent mesenchymal stem cells
Peimin Chen, Ming‐Shyen Yen, Ko‐Jiunn Liu, Huey‐Kang Sytwu, Betty Linju Yen · 2011 · Journal of Biomedical Science
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Michael A. Matthay, Arnaud Goolaerts, James Philip Howard, Jae Wook Lee · 2010 · Critical Care Medicine
Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation
Angelo S. Mao, Berna Özkale, Nisarg J. Shah, Kyle H. Vining, Tiphaine Descombes, Liyuan Zhang, Christina M. Tringides, Sing Wan Wong, Jae‐Won Shin, David T. Scadden et al. · 2019 · Proceedings of the National Academy of Sciences
Prostaglandin E2 plays a key role in the immunosuppressive properties of adipose and bone marrow tissue-derived mesenchymal stromal cells
Rosa Yañez, Alberto Oviedo, Montserrat Aldea, Juan Antonio Bueren, Maria Luisa Lamana · 2010 · Experimental Cell Research
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Jessie R. Lavoie, Michael Rosu‐Myles · 2013 · Biochimie
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Vitale Miceli, Matteo Bulati, Gioacchin Iannolo, Giovanni Zito, Alessia Gallo, Pier Giulio Conaldi · 2021 · International Journal of Molecular Sciences
Antibacterial effect of mesenchymal stem cells against Escherichia coli is mediated by secretion of beta‐ defensin‐ 2 via toll‐ like receptor 4 signalling
Dong Kyung Sung, Yun Sil Chang, Se In Sung, Hye Soo Yoo, So Yoon Ahn, Won Soon Park · 2015 · Cellular Microbiology
Mesenchymal stem cells prevent hypertrophic scar formation via inflammatory regulation when undergoing apoptosis.
Shi-Yu Liu, Lan Jiang, Haijian Li, Haigang Shi, Hailang Luo, Yong-Jie Zhang, Chun-Yan Yu, Yan Jin · 2014 · Journal of Investigative Dermatology
Long-term reprogramming of the innate immune system
Jorge Domínguez‐Andrés, Mihai Gheorghe Netea · 2018 · Journal of Leukocyte Biology
Immunoregulatory potential of mesenchymal stem cells following activation by macrophage-derived soluble factors
Laura Saldaña, Fátima Bensiamar, Gema Vallés, Francisco J. Mancebo, Eduardo García‐Rey, Nuria E. Vilaboa · 2019 · Stem Cell Research & Therapy
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Daniel J. Weiss, Ivan Bertoncello, Zea Borok, Carla Kim, Angela Panoskaltsis‐Mortari, Seth Reynolds, Mauricio Rojas, Barry R. Stripp, David Warburton, Darwin J. Prockop · 2011 · Proceedings of the American Thoracic Society
Mesenchymal stem cell-educated macrophages
Eggenhofer, Elke, Hoogduijn, Martin J · 2012 · Transplantation Research
Umbilical Cord-Derived Mesenchymal Stromal Cells Modulate Monocyte Function to Suppress T Cell Proliferation
Antony J. Cutler, Vasanti Limbani, J. Girdlestone, C. Navarrete · 2010 · Journal of Immunology
Umbilical Cord Mesenchymal Stem Cell Treatment for Crohn's Disease: A Randomized Controlled Clinical Trial
Jian Zhang, Samei Lv, Xiaojing Liu, Bin Song, Liping Shi · 2017 · Gut and Liver
Activity of mesenchymal stem cells in therapies for chronic skin wound healing
Austin Nuschke · 2013 · Organogenesis
Mesenchymal stem cells: biological properties and clinical applications
Ignacio García‐Gómez, Gema Elvira, Agustín G. Zapata, Maria Luisa Lamana, Manuel R. Ramírez, Javier Garcı́a-Castro, Mariano García Arranz, Ángeles Vicente, Juan Antonio Bueren, Damián García‐Olmo · 2010 · Expert Opinion on Biological Therapy
Paracrine/endocrine mechanism of stem cells on kidney repair: role of microvesicle-mediated transfer of genetic information
Giovanni Camussi, Maria Chiara Deregibus, Ciro Tetta · 2009 · Current Opinion in Nephrology & Hypertension
Human Oral Mucosa and Gingiva
Q.Z. Zhang, A.L. Nguyen, Weiwei Yu, Anh D. Le · 2012 · Journal of Dental Research
Unraveling the Mesenchymal Stromal Cells' Paracrine Immunomodulatory Effects
Fontaine, Magali J., Shih, Hank, Schäfer, Richard, Pittenger, Mark F. · 2016 · Transfusion Medicine Reviews
CCL2 and CXCL12 Derived from Mesenchymal Stromal Cells Cooperatively Polarize IL-10+ Tissue Macrophages to Mitigate Gut Injury
Jayeeta Giri, Rahul Das, Emily Nylen, Raghavan Chinnadurai, Jacques Galipeau · 2020 · Cell Reports
Combination therapy of menstrual derived mesenchymal stem cells and antibiotics ameliorates survival in sepsis
Francisca Alcayaga‐Miranda, Jimena Cuenca, Aldo Martin, Luis Contreras, Fernando E. Figueroa, Maroun Khoury · 2015 · Stem Cell Research & Therapy
Pre-conditioning mesenchymal stromal cell spheroids for immunomodulatory paracrine factor secretion
Joshua A. Zimmermann, Todd C. McDevitt · 2013 · Cytotherapy
Reactive Bone Marrow Stromal Cells Attenuate Systemic Inflammation via sTNFR1
Hiroshi Yagi, Alejandro Soto–Gutiérrez, Nalu Navarro–Álvarez, Yaakov Nahmias, Yoni Goldwasser, Yuko Kitagawa, Arno W. Tilles, Ronald Gary Tompkins, Biju Parekkadan, Martin L. Yarmush · 2010 · Molecular Therapy
Concise Review: Mesenchymal Stem (Stromal) Cells: Biology and Preclinical Evidence for Therapeutic Potential for Organ Dysfunction Following Trauma or Sepsis
Michael A. Matthay, Shibani Pati, Jae Woo Lee · 2016 · Stem Cells
Mesenchymal stromal cells in cancer: A review of their immunomodulatory functions and dual effects on tumor progression
Galland, Sabine, Stamenkovic, Ivan · 2020 · The Journal of Pathology
Bone regeneration in inflammation with aging and cell-based immunomodulatory therapy
Junichi Kushioka, Simon Kwoon‐Ho Chow, Masakazu Toya, Masanori Tsubosaka, Huaishuang Shen, Qi Gao, Xueping Li, Ning Zhang, Stuart Barry Goodman · 2023 · Inflammation and Regeneration
Human mesenchymal stem cells reduce the severity of acute lung injury in a sheep model of bacterial pneumonia
Sven Asmussen, Hiroshi Ito, Daniel Lee Traber, Jae Woo Lee, Robert A. Cox, Hal K. Hawkins, Daniel Francis McAuley, David H. McKenna, Lillian D. Traber, Hanjing Zhuo et al. · 2014 · Thorax
Mesenchymal Stem Cells Induce Suppressive Macrophages Through Phagocytosis in a Mouse Model of Asthma
Faouzi Braza, Stéphanie Dirou, Virginie F Forest, Vincent Sauzeau, Dorian Hassoun, Julie Chesné, Marie‐Aude Cheminant, Christine Sagan, A. Magnan, Patricia Lemarchand · 2016 · Stem Cells
Detrimental cross-talk between sepsis and acute kidney injury: new pathogenic mechanisms, early biomarkers and targeted therapies
Sergio Dellepiane, Marita Marengo, Vincenzo Cantaluppi · 2016 · Critical Care
Human umbilical cord blood-stem cells direct macrophage polarization and block inflammasome activation to alleviate rheumatoid arthritis
Tae–Hoon Shin, Hyung-Sik Kim, Tae‐Wook Kang, Byung-Chul Lee, Hwa-Yong Lee, Yoon-Jin Kim, Ji‐Hee Shin, Yoojin Seo, Soon Won Choi, Seunghee Lee et al. · 2016 · Cell Death and Disease
Identifying the Therapeutic Significance of Mesenchymal Stem Cells
Vineet Kumar Mishra, Hui-Hsuan Shih, Farzana Parveen, David Lenzen, Etsuro Ito, Te‐Fu Chan, Liang‐Yin Ke · 2020 · Cells
The Role of COX-2 and PGE2 in the Regulation of Immunomodulation and Other Functions of Mesenchymal Stromal Cells
Kulesza, Agnieszka, Paczek, Leszek, Burdzinska, Anna · 2023 · Biomedicines
CD105 (Endoglin)-Negative Murine Mesenchymal Stromal Cells Define a New Multipotent Subpopulation with Distinct Differentiation and Immunomodulatory Capacities
Per O. Anderson, Ana Belén Carrillo-Gálvez, Angélica García-Pérez, Marién Cobo, Francisco Martı́n · 2013 · PLoS ONE
Bone tissue formation with human mesenchymal stem cells and biphasic calcium phosphate ceramics: The local implication of osteoclasts and macrophages
Anne-Laure Gamblin, Meadhbh Á. Brennan, Audrey Renaud, Hideo Yagita∥, Frédéric Lézot, Dominique Heymann, Valérie Trichet, Pierre Layrolle · 2014 · Biomaterials
New Paradigms in Cell Therapy
Marcin Wysoczynki, Abdur Rahman Khan, Roberto Bolli · 2018 · Circulation Research
Exosomal miR-21 secreted by IL-1β-primed-mesenchymal stem cells induces macrophage M2 polarization and ameliorates sepsis
Mengying Yao, Bing Cui, Weihong Zhang, Wentao Ma, Gao-Feng Zhao, Lihua Xing · 2020 · Life Sciences
Cellular Immunotherapy for Septic Shock. A Phase I Clinical Trial
Lauralyn McIntyre, Duncan John Stewart, Shirley H. J. Mei, David W. Courtman, Irene Watpool, John Granton, John C. Marshall, Claúdia C. dos Santos, Keith R. Walley, Brent W. Winston et al. · 2017 · American Journal of Respiratory and Critical Care Medicine
Autophagy: a potential key contributor to the therapeutic action of mesenchymal stem cells
Sabrina Ceccariglia, Anna Cargnoni, Antonietta Rosa Silini, Ornella Parolini · 2019 · Autophagy
Mesenchymal stem cells as anti-inflammatories: Implications for treatment of Duchenne muscular dystrophy
Thomas E. Ichim, Doru T Alexandrescu, Fabio Solano, Fabian Lara, Rosalia De Necochea Campion, Eugenia Paris, Erik J. Woods, Michael P. Murphy, Constantin A Dasanu, Amit N. Patel et al. · 2009 · Cellular Immunology
Therapeutic Potential of Mesenchymal Stem Cells for Severe Acute Lung Injury
Michael A. Matthay, Bruce Thompson, Elizabeth J. Read, David H. McKenna, Kathleen D. Liu, Carolyn S. Calfee, Jae Woo Lee · 2010 · CHEST Journal
Bone regeneration with micro/nano hybrid-structured biphasic calcium phosphate bioceramics at segmental bone defect and the induced immunoregulation of MSCs
Yu Zhu, Kun Zhang, Rui Zhao, Xingjiang Ye, Xuening Chen, Zhanwen Xiao, Xiao Yang, Xiangdong Zhu, Kai Zhang, Yujiang Fan et al. · 2017 · Biomaterials
Mesenchymal stem cell-derived extracellular vesicles for the treatment of acute respiratory distress syndrome
Aswin Abraham, Anna D. Krasnodembskaya · 2019 · Stem Cells Translational Medicine
Intravenous Mesenchymal Stem Cells Improve Survival and Motor Function in Experimental Amyotrophic Lateral Sclerosis
Antonio Uccelli, Marco Milanese, Maria Cristina Principato, Sara Morando, Tiziana Bonifacino, Laura Vergani, Debora Giunti, Adriana Voci, Enrico Carminati, Francesco Giribaldi et al. · 2012 · Molecular Medicine
Mesenchymal stromal cells orchestrate follicular lymphoma cell niche through the CCL2-dependent recruitment and polarization of monocytes
Fabien Guilloton, Gersende Caron, Cédric Menard, Céline Pangault, Patricia Amé-Thomas, Joëlle Dulong, John De Vos, Delphine Rossille A, Cathérine Henry, Thierry Lamy et al. · 2012 · Blood
Mesenchymal stem/stromal cells precondition lung monocytes/macrophages to produce tolerance against allo- and autoimmunity in the eye
Jung Hwa Ko, Hyun Ju Lee, Hyun Jeong Jeong, Mee Kum Kim, Won Ryang Wee, Sun-ok Yoon, Hosoon Choi, Darwin J. Prockop, Joo Youn Oh · 2015 · Proceedings of the National Academy of Sciences
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Viktória Kónya, Gunther Marsche, Rufina Schuligoi, Ákos Heinemann · 2013 · Pharmacology & Therapeutics
Cell-based Therapy for Acute Organ Injury
Antoine Monsel, Yinggang Zhu, Stéphane Gennai, Qi Hao, Jia Liu, Jae Woo Lee · 2014 · Anesthesiology
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Vito Fanelli, Vito Marco Ranieri · 2015 · Annals of the American Thoracic Society
A randomized trial of recombinant human granulocyte-macrophage colony stimulating factor for patients with acute lung injury*
Robert Paine, Theodore J. Standiford, Ronald E. Dechert, Marc Moss, Greg S. Martin, Andrew L. Rosenberg, Victor John Thannickal, Ellen Lyda Burnham, Morton B. Brown, Robert C. Hyzy · 2011 · Critical Care Medicine
Clinical potential of mesenchymal stem/stromal cell-derived extracellular vesicles
Bernd Giebel, Lambros Kordelas, Verena Börger · 2017 · Stem Cell Investigation
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Guido Moll, Regina Jitschin, Lena von Bahr, Ida Rasmusson, Berit Sundberg, Lena Lönnies, Graciela Elgue, Kristina Nilsson‐Ekdahl, Dimitrios Mougiakakos, John D. Lambris et al. · 2011 · PLoS ONE
Injectable osteogenic microtissues containing mesenchymal stromal cells conformally fill and repair critical-size defects
Ramkumar T. Annamalai, Xiaowei Hong, Nicholas G. Schott, Gopinath Tiruchinapally, Benjamin Lévi, Jan P. Stegemann · 2019 · Biomaterials
Potential application of mesenchymal stem cells in acute lung injury
Jae Woo Lee, Naveen Gupta, Vladimir B. Serikov, Michael A. Matthay · 2009 · Expert Opinion on Biological Therapy
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Yantao He, Dongmei Chen, Lingling Yang, Qiaoni Hou, Huiming Ma, Xian Xu · 2018 · Stem Cell Research & Therapy
Anti-inflammatory protein TSG-6 secreted by bone marrow mesenchymal stem cells attenuates neuropathic pain by inhibiting the TLR2/MyD88/NF-κB signaling pathway in spinal microglia
Hao Yang, Lingmin Wu, Huimin Deng, Yuanli Chen, Huanping Zhou, Meiyun Liu, Shaochen Wang, Zheng Li, Lina Zhu, Xin Lv · 2020 · Journal of Neuroinflammation
Bone Marrow Derived Mesenchymal Stem Cells Inhibit Inflammation and Preserve Vascular Endothelial Integrity in the Lungs after Hemorrhagic Shock
Shibani Pati, Michael H. Gerber, Tyler D. Menge, Kathryn A. Wataha, Yuhai Zhao, John Adam Baumgartner, Jing Zhao, Phillip A. Letourneau, Maria del Pilar Huby, Lisa A. Baer et al. · 2011 · PLoS ONE
Allogeneic mesenchymal stem cell and mesenchymal stem cell-differentiated chondrocyte suppress the responses of type II collagen-reactive T cells in rheumatoid arthritis.
Zhaohui Zheng, X. Y. Li, Jin Ding, Jun Jia, P. Zhu · 2007 · Lara D. Veeken
Human Mesenchymal Stem (Stromal) Cells Promote the Resolution of Acute Lung Injury in Part through Lipoxin A4
Xiaohui Fang, Jason Anthony Abbott, Linda Cheng, Jennifer K. Colby, Jae Woo Lee, Bruce David Levy, Michael A. Matthay · 2015 · The Journal of Immunology
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H. Pape, E. Moore, T. McKinley, A. Sauaia · 2022 · Injury
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Yoojin Seo, Hyung‐Sik Kim, In‐Sun Hong · 2019 · Stem Cells International
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Günter Lepperdinger · 2011 · Current Opinion in Immunology
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Jae‐Yol Lim, TacGhee Yi, Jeong‐Seok Choi, Yun Ho Jang, Song-Yi Lee, Hun Jung Kim, Sun U. Song, Young‐Mo Kim · 2012 · Oral Oncology
Human umbilical cord mesenchymal stem cells reduce systemic inflammation and attenuate LPS-induced acute lung injury in rats
Jianjun Li, Dong Li, Xiaomei Liu, Shuhai Tang, Fengcai Wei · 2012 · Journal of Inflammation
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Activated Mesenchymal Stem Cells Interact with Antibiotics and Host Innate Immune Responses to Control Chronic Bacterial Infections
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Toshinori Ueno, Ayumu Nakashima, Shigehiro Doi, Takeshi Kawamoto, Kiyomasa K. Honda, Yukio Yokoyama, Toshiki Doi, Yukihito Higashi, Noriaki Yorioka, Yukio Kato et al. · 2013 · Kidney International
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Ling Wei, Zheng Zachory Wei, Michael Qize Jiang, Osama Mohamad, Shan Ping Yu · 2017 · Progress in Neurobiology
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Rebecca L. Toonkel, Joshua M. Hare, Michael A. Matthay, Marilyn K. Glassberg · 2013 · American Journal of Respiratory and Critical Care Medicine
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Hafsa Munir, Helen Michelle McGettrick · 2015 · Stem Cells and Development
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Allogeneic mesenchymal stem cells: Agents of immune modulation
Karen English, Bernard P. Mahon · 2011 · Journal of Cellular Biochemistry
Intravenous injection of mesenchymal stem cells is effective in treating liver fibrosis
Zhao, Wei · 2012 · World Journal of Gastroenterology
Inactivated Mesenchymal Stem Cells Maintain Immunomodulatory Capacity
Franka Luk, Samantha F. H. de Witte, Sander S. Korevaar, Marieke Roemeling-van Rhijn, Marcella Franquesa, Tanja Strini, Sandra van den Engel, Madhusudhana Gargesha, Debashish Roy, Frank J. M. F. Dor et al. · 2016 · Stem Cells and Development
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HIPPO SIGNALING CONTROLS NLRP3 ACTIVATION AND GOVERNS IMMUNOREGULATION OF MESENCHYMAL STEM CELLS IN MOUSE LIVER INJURY
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