Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

Németh, Krisztián, Leelahavanichkul, Asada, Yuen, Peter S T, Mayer, Balázs, Parmelee, Alissa, Doi, Kent, Robey, Pamela G, Leelahavanichkul, Kantima +6 more·2009·Nature Medicine

DOI 10.1038/nm.1905

Cited by (1,003)

Items 501–600 of 1,003

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Lee, Kuei-Chuan, Lin, Han-Chieh, Huang, Yi-Hsiang, Hung, Shih-Chieh · 2015 · Journal of Hepatology
High Local Concentrations of Intradermal MSCs Restore Skin Integrity and Facilitate Wound Healing in Dystrophic Epidermolysis Bullosa
Tobias Kühl, Markus Mezger, Ingrid Haußer, Rupert Handgretinger, Leena Bruckner‐Tuderman, Alexander Nyström · 2015 · Molecular Therapy
Direct Intrathecal Implantation of Mesenchymal Stromal Cells Leads to Enhanced Neuroprotection via an NFκB-Mediated Increase in Interleukin-6 Production
Peter A. Walker, Matthew T. Harting, Fernando Jiménez, Shinil K. Shah, Shibani Pati, Pramod K. Dash, Charles S. Cox · 2009 · Stem Cells and Development
Mesenchymal stromal cells: a key player in ‘innate tolerance’?
Francesco Dazzi, Luciene M. Lopes, Ling Weng · 2012 · Immunology
Study of Bone Marrow and Embryonic Stem Cell-Derived Human Mesenchymal Stem Cells for Treatment ofEscherichia coliEndotoxin-Induced Acute Lung Injury in Mice
Qi Hao, Yinggang Zhu, Antoine Monsel, Stéphane Gennai, Travis Lee, Fengyun Xu, Jae Wook Lee · 2015 · Stem Cells Translational Medicine
Clinical Translation of Mesenchymal Stromal Cell Therapies in Nephrology
Norberto Perico, Federica Casiraghi, Giuseppe Remuzzi · 2017 · Journal of the American Society of Nephrology
The Immunomodulatory Effects of Mesenchymal Stem Cells on Regulatory B Cells
Jialing Liu, Qiuli Liu, Xiaoyong Chen · 2020 · Frontiers in Immunology
Gene regulation of intracellular adhesion molecule-1 (ICAM-1): A molecule with multiple functions
Mona Singh, Mony Thakur, Manish Mishra, Manisha Yadav, Raj Kamal Vibhuti, Athira M. Menon, Girima Nagda, Ved Prakash Dwivedi, Tikam Chand Dakal, Vinod Yadav · 2021 · Immunology Letters
The leaky gut and the gut microbiome in sepsis – targets in research and treatment
Wiwat Chancharoenthana, Supitcha Kamolratanakul, Marcus Josephus Schultz, Asada Leelahavanichkul · 2023 · Clinical Science
Immunomodulatory Activity of Mesenchymal Stem Cells
Johanne M Kaplan, Michele E. Youd, Tracey A. Lodie · 2011 · Current Stem Cell Research & Therapy
Mesenchymal Stromal Cell Derived Extracellular Vesicles Reduce Hypoxia-Ischaemia Induced Perinatal Brain Injury
Claudia Sisa, Sharad Kholia, Jordan Naylor, Maria Beatriz Herrera Sanchez, Stefania Bruno, Maria Chiara Deregibus, Giovanni Camussi, Jameel M. Inal, Sigrun Lange, Mariya Hristova · 2019 · Frontiers in Physiology
Cryopreserved, Xeno-Free Human Umbilical Cord Mesenchymal Stromal Cells Reduce Lung Injury Severity and Bacterial Burden in Rodent Escherichia coli–Induced Acute Respiratory Distress Syndrome
Gerard F. Curley, Mirjana Jerkić, Steve Dixon, Grace Hogan, Claire H. Masterson, Daniel P. O’Toole, James Devaney, John Gerard Laffey · 2016 · Critical Care Medicine
Potential application of mesenchymal stem cells and their exosomes in lung injury: an emerging therapeutic option for COVID-19 patients
Sara Al‐Khawaga, Essam Mohamed Abdelalim · 2020 · Stem Cell Research & Therapy
Mesenchymal stromal (stem) cell therapy modulates miR-193b-5p expression to attenuate sepsis-induced acute lung injury
Claúdia C. dos Santos, Hajera Amatullah, Chirag M. Vaswani, Tatiana Maron‐Gutierrez, Michael Kim, Shirley H. J. Mei, Katalin Szászi, Ana Paula Teixeira Monteiro, Amir Khashayar Varkouhi, Raquel Herreroz et al. · 2021 · European Respiratory Journal
miR-335 Correlates with Senescence/Aging in Human Mesenchymal Stem Cells and Inhibits Their Therapeutic Actions Through Inhibition of AP-1 Activity
María Tomé, Juan Carlos Sepúlveda, Mario Delgado, José A. Andrades, Judith Campisi, Manuel A. González, António Bernad · 2014 · Stem Cells
Mesenchymal Stromal Cells Affect Disease Outcomes via Macrophage Polarization
Guoping Zheng, Menghua Ge, Guanguan Qiu, Qiang Shu, Jianguo Xu · 2015 · Stem Cells International
Mesenchymal stem cells and infectious diseases: Smarter than drugs
Éva Mezey, Krisztián Németh · 2015 · Immunology Letters
Mesenchymal stem cells transplantation ameliorates glomerular injury in streptozotocin-induced diabetic nephropathy in rats via inhibiting macrophage infiltration
Shasha Lv, Gang Liu, Jianping Wang, Weiwei Wang, Jing Cheng, Ai-Li Sun, Hai-Ying Liu, Huibin Nie, Mo-Ran Su, Guangju Guan · 2013 · International Immunopharmacology
On the interactions between mesenchymal stem cells and regulatory T cells for immunomodulation in transplantation
Anja U. Engela, Carla C. Baan, Frank J. M. F. Dor, Willem Weimar, Martin Johannes Hoogduijn · 2012 · Frontiers in Immunology
The role of the immune system in tendon healing: a systematic review.
Emanuele Chisari, L. Rehak, W. Khan, N. Maffulli · 2020 · British Medical Bulletin
Sepsis: From Pathophysiology to Individualized Patient Care
Ildikó László, Domonkos Trásy, Zsolt Molnár, János Fazakas · 2015 · Journal of Immunology Research
Mesenchymal stem cells and cancer: Friends or enemies?
Hong, In-Sun, Lee, Hwa-Yong, Kang, Kyung-Sun · 2014 · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Mesenchymal stem cells attenuate myocardial functional depression and reduce systemic and myocardial inflammation during endotoxemia
Brent R. Weil, Mariuxi C. Manukyan, Jeremy L. Herrmann, Yue Wang, Aaron M. Abarbanell, Jeffrey A. Poynter, Daniel R. Meldrum · 2010 · Surgery
Innate Immunity in the Therapeutic Actions of Endothelial Progenitor Cells in Pulmonary Hypertension
Mark L. Ormiston, Yupu Deng, Duncan John Stewart, David W. Courtman · 2009 · American Journal of Respiratory Cell and Molecular Biology
Immune modulation with primed mesenchymal stem cells delivered via biodegradable scaffold to repair an Achilles tendon segmental defect
Erdem Aktaş, Connie S. Chamberlain, Erin E. Saether, Sarah E. Duenwald-Kuehl, Jaclyn Kondratko‐Mittnacht, Michael Stitgen, Jae-Sung Lee, Anna E. B. Clements, William L. Murphy, Ray Vanderby · 2016 · Journal of Orthopaedic Research®
Human adipose tissue-derived mesenchymal stem cells alleviate atopic dermatitis via regulation of B lymphocyte maturation
Tae–Hoon Shin, Byung‐Chul Lee, Soon Won Choi, Ji‐Hee Shin, Insung Kang, Jin Young Lee, Jae-Jun Kim, Hong-Ki Lee, Jae-Eon Jung, Yong-Woon Choi et al. · 2016 · Oncotarget
The Macrophage Response Is Driven by Mesenchymal Stem Cell-Mediated Metabolic Reprogramming
Luque-Campos, Noymar, Bustamante-Barrientos, Felipe A., Pradenas, Carolina, García, Cynthia, Araya, María Jesús, Bohaud, Candice, Contreras-López, Rafael, Elizondo-Vega, Roberto, Djouad, Farida, Luz-Crawford, Patricia et al. · 2021 · Frontiers in Immunology
Stem cells in sepsis and acute lung injury
Sushma K. Cribbs, Michael A. Matthay, Greg S. Martin · 2010 · Critical Care Medicine
Mussel-Inspired Nanostructures Potentiate the Immunomodulatory Properties and Angiogenesis of Mesenchymal Stem Cells
Tao Li, Hongshi Ma, Hongzhi Ma, Zhenjiang Ma, Lei Qiang, Zezheng Yang, Xiaoxiao Yang, Xiaojun Zhou, Kerong Dai, Jinwu Wang · 2019 · ACS Applied Materials & Interfaces
Network Analysis of Transcriptional Responses Induced by Mesenchymal Stem Cell Treatment of Experimental Sepsis
Claúdia C. dos Santos, Srinivas Murthy, Pingzhao Hu, Yuexin Shan, Jack J. Haitsma, Shirley H. J. Mei, Duncan John Stewart, Wayne Conrad Liles · 2012 · American Journal Of Pathology
Preserving Prostaglandin E2 Level Prevents Rejection of Implanted Allogeneic Mesenchymal Stem Cells and Restores Postinfarction Ventricular Function
Sanjiv Dhingra, Peng Li, Xi‐Ping Huang, Jian Guo, Jun Wu, Anton Mihic, Shuhong Li, Wang‐Fu Zang, Daniel Shen, Richard D. Weisel et al. · 2013 · Circulation
Concise Review: Mesenchymal Stromal Cell-Based Approaches for the Treatment of Acute Respiratory Distress and Sepsis Syndromes
Christian L. Johnson, Yorick Soeder, Marc Hendrik Dahlke · 2017 · Stem Cells Translational Medicine
Epithelial Interactions and Local Engraftment of Lung-Resident Mesenchymal Stem Cells
Linda Badri, Natalie Walker, Takashi Ohtsuka, Zhuo Wang, Mario Delmar, Andrew Flint, Marc L. Peters-Golden, Galen B. Toews, David J. Pinsky, Paul H. Krebsbach et al. · 2011 · American Journal of Respiratory Cell and Molecular Biology
Stem Cells and Cell Therapies in Lung Biology and Diseases: Conference Report
Daniel J. Weiss, Jason H. T. Bates, Thomas W. Gilbert, Wayne Conrad Liles, Carolyn Lutzko, Jayaraj Rajagopal, Darwin J. Prockop · 2013 · Annals of the American Thoracic Society
Mesenchymal Stem Cells for the Treatment of Idiopathic Pulmonary Fibrosis
Argyrios Tzouvelekis, Rebecca L. Toonkel, Τheodoros Karampitsakos, Kantha Medapalli, Ioanna Ninou, Vassilis Aidinis, Demosthenes E. Bouros, Marilyn K. Glassberg · 2018 · Frontiers in Medicine
Mesenchymal stem cells (MSCs) as skeletal therapeutics–an update
Hamid Saeed, Muhammad Ahsan, Zikria Saleem, Mehwish Iqtedar, Muhammad Fajrul Islam, Zeeshan Danish, Asif Manzoor Khan · 2016 · Journal of Biomedical Science
Hypoxia-preconditioned mesenchymal stem cells ameliorate ischemia/reperfusion-induced lung injury
Yung-Yang Liu, Chi‐Huei Chiang, Shih‐Chieh Hung, Chih‐Feng Chian, Chen‐Liang Tsai, Wei‐Chih Chen, Haibo Zhang · 2017 · PLoS ONE
Mesenchymal stem cells: Biological characteristics and application in disease therapy
Songyue Lou, Yongtao Duan, Huizong Nie, Xujie Cui, Jialing Du, Yongfang Yao · 2021 · Biochimie
Endothelial Progenitor Cells and a Stromal Cell–derived Factor-1α Analogue Synergistically Improve Survival in Sepsis
Hongkuan Fan, Andrew Jackson Goodwin IV, Eugene Chang, Basilia Zingarelli, Keith Thomas Borg, Shuwen Guan, Perry V. Halushka, James A. Cook · 2014 · American Journal of Respiratory and Critical Care Medicine
Embryonic Stem Cell-Derived Mesenchymal Stem Cells (MSCs) Have a Superior Neuroprotective Capacity Over Fetal MSCs in the Hypoxic-Ischemic Mouse Brain
Kate Hawkins, Michelangelo Corcelli, Kate Dowding, Anna Maria Ranzoni, Filipa Vlahova, Kwan-Leong Hau, Avina K. Hunjan, Donald Peebles, Pierre Gressèns, Henrik Hagberg et al. · 2018 · Stem Cells Translational Medicine
Mesenchymal stromal cell injection protects against oxidative stress in Escherichia coli–induced acute lung injury in mice
Sally Mahmoud Shalaby, Amal S. El‐Shal, Somia Hassan Abd-Allah, Assmaa O. Selim, Sally A. Selim, Zienab A. Gouda, Dalia M. Abd El Motteleb, HalaE Zanfaly, Heba M El-Assar, Shymaa Abdelazim · 2014 · Cytotherapy
The Regenerative Role of the Fetal and Adult Stem Cell Secretome
Sveva Bollini, Chiara Gentili, Roberta Tasso, Ranieri Cancedda · 2013 · Journal of Clinical Medicine
Mesenchymal Stromal Cells from Fetal and Maternal Placenta Possess Key Similarities and Differences: Potential Implications for Their Applications in Regenerative Medicine
Andrea Papait, Elsa Vertua, Marta Magatti, Sabrina Ceccariglia, Silvia De Munari, Antonietta Rosa Silini, Michal Sheleg, Racheli Ofir, Ornella Parolini · 2020 · Cells
Extracellular vesicles derived from mesenchymal stem cells — a novel therapeutic tool in infectious diseases
Tasaduq Manzoor, Afnan Saleem, Nida Farooq, Lateef Ahmad Dar, Junaid Nazir, Sahar Saleem, Sameena Ismail, Mudasir Bashir Gugjoo, Parvaiz Ahmad Shiekh, Syed Mudasir Ahmad · 2023 · Inflammation and Regeneration
Enhanced Immunosuppression of T Cells by Sustained Presentation of Bioactive Interferon-γ Within Three-Dimensional Mesenchymal Stem Cell Constructs
Joshua A. Zimmermann, Marian H. Hettiaratchi, Todd C. McDevitt · 2016 · Stem Cells Translational Medicine
Mesenchymal stem cells enhance NOX2-dependent reactive oxygen species production and bacterial killing in macrophages during sepsis
R. Rabani, Allen Volchuk, Mirjana Jerkić, Lindsay Ormesher, Linda Garcés‐Ramírez, Johnathan Canton, Claire H. Masterson, Stéphane Gagnon, Kate Colette Tatham, John C. Marshall et al. · 2018 · European Respiratory Journal
A single-cell atlas of the myometrium in human parturition
Roger Piqué-Regi, Roberto J. Romero, Valeria Garcia‐Flores, Azam Peyvandipour, Adi Laurentiu Tarca, Errile Pusod, José Galaz, Derek Miller, Gaurav Bhatti, Robert Para et al. · 2022 · JCI Insight
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Mamdouh Yousif Elgendy, Shimaa E. Ali, Ahmed Abdal Dayem, Riad Hassan Khalil, Moustafa M. Moustafa, Mohamed Abdelsalam · 2024 · Aquaculture International
TLR9 Agonist Protects Mice from Radiation-Induced Gastrointestinal Syndrome
Subhrajit Saha, Payel Bhanja, Laibin Liu, Alan A. Alfieri, Dong Su Yu, Ekambar R. Kandimalla, Sudhir Agrawal, Chandan Guha · 2012 · PLoS ONE
Role of the immune system in regeneration and its dynamic interplay with adult stem cells
Prasad Abnave, Éric Ghigo · 2018 · Seminars in Cell and Developmental Biology
Herbal formula BaWeiBaiDuSan alleviates polymicrobial sepsis-induced liver injury via increasing the gut microbiota Lactobacillus johnsonii and regulating macrophage anti-inflammatory activity in mice
Xiaoqing Fan, Chu-Tian Mai, Ling Zuo, Jumin Huang, Chun Xie, Zebo Jiang, Runze Li, Xiaojun Yao, Xing‐Xing Fan, Qibiao Wu et al. · 2022 · Acta Pharmaceutica Sinica B
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Yuran Su, Chenyu Xu, Wen Cheng, Yanmei Zhao, Lei Sui, Yanhong Zhao · 2023 · International Journal of Molecular Sciences
Organoids transplantation attenuates intestinal ischemia/reperfusion injury in mice through L-Malic acid-mediated M2 macrophage polarization
Fang-Ling Zhang, Zhen Hu, Yifan Wang, Wenjuan Zhang, Bowei Zhou, Qi‐Shun Sun, Zebin Lin, Ke‐Xuan Liu · 2023 · Nature Communications
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Cynthia M. Coleman, Caroline M. Curtin, Frank Barry, Cathal O’Flatharta, Mary J. Murphy · 2010 · Human Gene Therapy
Mesenchymal stromal (stem) cells suppress pro-inflammatory cytokine production but fail to improve survival in experimental staphylococcal toxic shock syndrome
Hani Kim, Ilyse Darwish, Maria-Fernanda Monroy, Darwin J. Prockop, W. Conrad Liles, Kevin C. Kain · 2014 · BMC Immunology
Transplanted Bone Marrow–Derived Circulating PDGFRα+ Cells Restore Type VII Collagen in Recessive Dystrophic Epidermolysis Bullosa Mouse Skin Graft
Shin Iinuma, Eriko Aikawa, Katsuto Tamai, Ryo Fujita, Yasushi Kikuchi, Takenao Chino, Junichi Kikuta, John Alexander McGrath, Jouni Uitto, Masaru Ishii et al. · 2015 · The Journal of Immunology
Conditioned Media from Adipose-Tissue-Derived Mesenchymal Stem Cells Downregulate Degradative Mediators Induced by Interleukin-1βin Osteoarthritic Chondrocytes
Julia Platas, María Isabel Guillén, María Dolores Pérez del Caz, Francisco Gomar, Vicente Mirabet, María José Alcaraz · 2013 · Mediators of Inflammation
Bone Marrow Mesenchymal Stem Cell-Based Engineered Cartilage Ameliorates Polyglycolic Acid/Polylactic Acid Scaffold-Induced Inflammation Through M2 Polarization of Macrophages in a Pig Model
Jinping Ding, Bo Chen, Tao Lv, Xia Liu, Xin Fu, Qian Wang, Yan Li, Ning Kang, Yilin Cao, Ran Xiao · 2016 · Stem Cells Translational Medicine
The effects of conditioned media generated by polarized macrophages on the cellular behaviours of bone marrow mesenchymal stem cells
Xiao‐Tao He, Xuan Li, Yuan Yin, Rui‐Xin Wu, Xinyue Xu, Fa‐Ming Chen · 2017 · Journal of Cellular and Molecular Medicine
Fibroblast Growth Factor-1 Is a Mesenchymal Stromal Cell-Secreted Factor Stimulating Proliferation of Osteoarthritic Chondrocytes in Co-Culture
Ling Wu, Jeroen Leijten, Clemens van Blitterswijk, Marcel Karperien · 2013 · Stem Cells and Development
Dose-Dependent Effect of Intravenous Administration of Human Umbilical Cord-Derived Mesenchymal Stem Cells in Neonatal Stroke Mice
Emi Tanaka, Yuko Ogawa, Takeo Mukai, Yoshiaki Sato, Takashi Hamazaki, Tokiko Nagamura‐Inoue, Mariko Harada‐Shiba, Haruo Shintaku, Masahiro Tsuji · 2018 · Frontiers in Neurology
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Xiao He, Shanmu Ai, Wei Guo, Yi Yang, Zhengguo Wang, Dongpo Jiang, Xiang Ming Xu · 2018 · Translational research
Newly Defined ATP-Binding Cassette Subfamily B Member 5 Positive Dermal Mesenchymal Stem Cells Promote Healing of Chronic Iron-Overload Wounds via Secretion of Interleukin-1 Receptor Antagonist
Seppe Vander Beken, Juliane C. de Vries, Barbara Meier-Schiesser, Patrick Meyer, Dongsheng Jiang, Anca Sindrilaru, Filipa F. Ferreira, Adelheid Hainzl, Susanne Schatz, Jana Muschhammer et al. · 2019 · Stem Cells
Current status of mesenchymal stem cell therapy for immune/inflammatory lung disorders: Gleaning insights for possible use in COVID-19
Betty Linju Yen, Ming‐Shyen Yen, Li‐Tzu Wang, Ko-Jiunn Liu, Huey‐Kang Sytwu · 2020 · Stem Cells Translational Medicine
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Soyoung Shin, Yonggoo Kim, Sikyoung Jeong, Sungyoup Hong, In‐Soo Kim, Woonjeong Lee, Seungphil Choi · 2013 · International Journal of Medical Sciences
Mesenchymal stromal cell derived CCL2 is required for accelerated wound healing
Derek Whelan, Noel M. Caplice, Anthony J. P. Clover · 2020 · Scientific Reports
Mesenchymal Stem Cells Reduce Murine Atherosclerosis Development
Vanessa Frodermann, Janine van Duijn, Melissa van Pel, Peter J. van Santbrink, Ilze Bot, Johan Kuiper, Saskia C.A. de Jager · 2015 · Scientific Reports
Mesenchymal stromal cells inhibit graft-versus-host disease of mice in a dose-dependent manner
Sunyoung Joo, Kyung‐Ah Cho, Yun-Jae Jung, Han‐Seong Kim, Seong‐Yeol Park∥, Yong‐Bock Choi∥, Kyeong‐Man Hong, So‐Youn Woo, Ju‐Young Seoh, Su Jin Cho et al. · 2010 · Cytotherapy
Regulatory factors of mesenchymal stem cell migration into injured tissues and their signal transduction mechanisms
Li Li, Jianxin Jiang · 2011 · Frontiers of Medicine
Collagen scaffold enhances the regenerative properties of mesenchymal stromal cells
Iran Rashedi, Nilesh P. Talele, Xinghua Wang, Boris Hinz, Milica Radisic, Armand Keating · 2017 · PLoS ONE
Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer
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Balancing macrophage polarization via stem cell-derived apoptotic bodies for diabetic wound healing
Jiayi Mao, Shutong Qian, Qiuyu Zhao, Binfan Zhao, Bolun Lu, Liucheng Zhang, Xiyuan Mao, Yuguang Zhang, Wenguo Cui, Xiaoming Sun · 2024 · Med
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Activated T-cells and pro-inflammatory cytokines differentially regulate prostaglandin E2 secretion by mesenchymal stem cells
Beáta Hegyi, Gyöngyi Kudlik, Éva Monostori, Ferenc Uher · 2012 · Biochemical and Biophysical Research Communications
Human Mesenchymal Stem Cells Inhibit Endothelial Proliferation and Angiogenesis via Cell–Cell Contact Through Modulation of the VE-Cadherin/β-Catenin Signaling Pathway
Tyler D. Menge, Michael H. Gerber, Kathryn A. Wataha, William C. Reid, Sushovan Guha, Charles S. Cox, Pramod K. Dash, Marvin S. Reitz, Aarif Yusuf Khakoo, Shibani Pati · 2012 · Stem Cells and Development
Combination therapy of mesenchymal stem cells and serelaxin effectively attenuates renal fibrosis in obstructive nephropathy
Brooke M. Huuskes, Andrea F. Wise, Alison J. Cox, Ee X. Lim, Natalie L. Payne, Darren J. Kelly, Chrishan S. Samuel, Sharon D. Ricardo · 2014 · The FASEB Journal
Analysis of Mitochondrial Transfer in Direct Co-cultures of Human Monocyte-derived Macrophages (MDM) and Mesenchymal Stem Cells (MSC)
Megan V. Jackson, Anna D. Krasnodembskaya · 2017 · BIO-PROTOCOL
Effects of Mesenchymal Stem Cell Treatment on Systemic Cytokine Levels in a Phase 1 Dose Escalation Safety Trial of Septic Shock Patients*
Kenny Schlosser, Jia-Pey Wang, Claúdia C. dos Santos, Keith R. Walley, John C. Marshall, Dean A. Fergusson, Brent W. Winston, John Thomas Granton, Irene Watpool, Duncan John Stewart et al. · 2019 · Critical Care Medicine
Bone marrow-derived clonal mesenchymal stem cells inhibit ovalbumin-induced atopic dermatitis
K Na, Han Sang Yoo, Y X Zhang, M.S. Choi, Kyung‐Yil Lee, TacGhee Yi, Sun U. Song, M-S Jeon · 2014 · Cell Death and Disease
Mesenchymal stem cells in idiopathic pulmonary fibrosis
Xiaohong Li, Shaojie Yue, Ziqiang Luo · 2017 · Oncotarget
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Barbara Fazekas, Matthew Dallas Griffin · 2020 · Kidney International
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Syam Nair, Eridan Rocha‐Ferreira, Bobbi Fleiss, Cora H. A. Nijboer, Pierre Gressèns, Carina E. Mallard, Henrik Hagberg · 2020 · Journal of Neurochemistry
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Preparation of Anti‐Inflammatory Mesenchymal Stem/Precursor Cells (MSCs) Through Sphere Formation Using Hanging‐Drop Culture Technique
Thomas J. Bartosh, Joni Ylöstalo · 2014 · Current Protocols in Stem Cell Biology
Airway Delivery of Soluble Factors from Plastic-Adherent Bone Marrow Cells Prevents Murine Asthma
Lavinia Ionescu, Rajesh S. Alphonse, Narcy G Arizmendi, Beverly Morgan, Melanie Abel, Farah Eaton, Marek Duszyk, Harissios Vliagoftis, Tamar R. Aprahamian, Kenneth Walsh et al. · 2011 · American Journal of Respiratory Cell and Molecular Biology
Mesenchymal stromal cells are more effective than the MSC secretome in diminishing injury and enhancing recovery following ventilator-induced lung injury
Mairéad Hayes, Gerard F. Curley, Claire H. Masterson, James Devaney, Daniel P. O’Toole, John Gerard Laffey · 2015 · Intensive Care Medicine Experimental
Nonsteroidal Anti-Inflammatory Drugs Increase TNF Production in Rheumatoid Synovial Membrane Cultures and Whole Blood
Theresa H. Page, Jeremy J. O. Turner, Anthony C. Brown, Emma M. Timms, Julia J. Inglis, Fionula M. Brennan, Brian M. J. Foxwell, Keith P. Ray, Marc Feldmann · 2010 · The Journal of Immunology
Extrinsic and intrinsic mechanisms by which mesenchymal stem cells suppress the immune system
V. Coulson-Thomas, Y. M. Coulson-Thomas, T. F. Gesteira, W. Kao · 2016 · The ocular surface
Alveolar Fluid Clearance in Pathologically Relevant Conditions: In Vitro and In Vivo Models of Acute Respiratory Distress Syndrome
Laura A. Huppert, Michael A. Matthay · 2017 · Frontiers in Immunology
Stem Cell–based Therapies for Sepsis
Colm Keane, Mirjana Jerkić, John Gerard Laffey · 2017 · Anesthesiology
Therapeutic effects of adipose-tissue-derived mesenchymal stromal cells and their extracellular vesicles in experimental silicosis
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Biological Considerations in Scaling Up Therapeutic Cell Manufacturing
Darshana S. Cherian, Tejasvini Bhuvan, Laurence Meagher, Tracy S P Heng · 2020 · Frontiers in Pharmacology
TGF-β1-Licensed Murine MSCs Show Superior Therapeutic Efficacy in Modulating Corneal Allograft Immune Rejection In Vivo
Kevin Lynch, Oliver Treacy, Xizhe Chen, Nick Murphy, Paul Lohan, Md Nahidul Islam, Ellen Donohoe, Matthew Dallas Griffin, Luke Watson, Steven McLoughlin et al. · 2020 · Molecular Therapy
Obesity-induced inflammation: The impact of the hematopoietic stem cell niche
Emily Bowers, K. Singer · 2021 · JCI Insight
Gene-modified Mesenchymal Stem Cells Protect Against Radiation-induced Lung Injury
Jianxin Xue, Xin Li, You Lü, Lu Gan, Lin Zhou, Yongsheng Wang, Jie Lan, Shurui Liu, Lan Ping Sun, Jia Li et al. · 2013 · Molecular Therapy
Intranasal versus Intraperitoneal Delivery of Human Umbilical Cord Tissue–Derived Cultured Mesenchymal Stromal Cells in a Murine Model of Neonatal Lung Injury
Liansheng Liu, Quanfu Mao, Sharon Chu, Marwan Mounayar, Reza Abdi, William L. Fodor, James F. Padbury, Monique E. De Paepe · 2014 · American Journal Of Pathology
CCR7 Guides Migration of Mesenchymal Stem Cell to Secondary Lymphoid Organs: A Novel Approach to Separate GvHD from GvL Effect
Hong Li, Yanming Jiang, Xiaoxia Jiang, Ximin Guo, Hongmei Ning, YuHang Li, Li Liao, Huiyu Yao, XiaoYan Wang, Yuanlin Liu et al. · 2014 · Stem Cells
Serum-Starved Adipose-Derived Stromal Cells Ameliorate Crescentic GN by Promoting Immunoregulatory Macrophages
Kazuhiro Furuhashi, Naotake Tsuboi, Asuka Shimizu, Takayuki Katsuno, Hangsoo Kim, Yosuke Saka, Takenori Ozaki, Yoshikazu Sado, Enyu Imai, Seiichi Matsuo et al. · 2013 · Journal of the American Society of Nephrology
Mesenchymal stem cell–conditioned medium prevents radiation-induced liver injury by inhibiting inflammation and protecting sinusoidal endothelial cells
Yixing Chen, Zhao‐Chong Zeng, Jing Sun, Haiying Zeng, Yan Huang, Zhen-Yu Zhang · 2015 · Journal of Radiation Research