The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis
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Citations
Cites
Bortezomib or High-Dose Dexamethasone for Relapsed Multiple Myeloma
Richardson, P. G., Sonneveld, P., Schuster, M. W., Irwin, D., Stadtmauer, E. A., Facon, T., Harousseau, J.-L., Ben-Yehuda, D., Lonial, S., Goldschmidt, H., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043445 · Cited by 2,491
Ohashi, P. S., Oehen, S., Buerki, K., Pircher, H., Ohashi, C. T., Odermatt, B., Malissen, B., Zinkernagel, R. M., & Hengartner, H. (1991) · Cell · doi:10.1016/0092-8674(91)90164-t · Cited by 1,173
Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
Pircher, H., Bürki, K., Lang, R., Hengartner, H., & Zinkernagel, R. M. (1989) · Nature · doi:10.1038/342559a0 · Cited by 1,019
Kuhn, D. J., Chen, Q., Voorhees, P. M., Strader, J. S., Shenk, K. D., Sun, C. M., Demo, S. D., Bennett, M. K., van Leeuwen, F. W. B., Chanan-Khan, A. A., et al. (2007) · Blood · doi:10.1182/blood-2007-01-065888 · Cited by 768
Self-citationChauhan, D., Catley, L., Li, G., Podar, K., Hideshima, T., Velankar, M., Mitsiades, C., Mitsiades, N., Yasui, H., Letai, A., et al. (2005) · Cancer Cell · doi:10.1016/j.ccr.2005.10.013 · Cited by 694
Antitumor Activity of PR-171, a Novel Irreversible Inhibitor of the Proteasome
Demo, S. D., Kirk, C. J., Aujay, M. A., Buchholz, T. J., Dajee, M., Ho, M. N., Jiang, J., Laidig, G. J., Lewis, E. R., Parlati, F., et al. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-4086 · Cited by 678
Self-citationAntigen processing by the proteasome
Kloetzel, P.-M. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35056572 · Cited by 637
MHC Class I Expression in Mice Lacking the Proteasome Subunit LMP-7
Fehling, H. J., Swat, W., Laplace, C., Kühn, R., Rajewsky, K., Müller, U., & von Boehmer, H. (1994) · Science · doi:10.1126/science.8066463 · Cited by 525
The Ubiquitin-Proteasome Pathway and Pathogenesis of Human Diseases
Schwartz, P., & Ciechanover, M. (1999) · Annual Review of Medicine · doi:10.1146/annurev.med.50.1.57 · Cited by 466
Altered peptidase and viral-specific T cell response in LMP2 mutant mice
Van Kaert, L., Ashton-Rickardt, P. G., Eichelberger, M., Gaczynska, M., Nagashima, K., Rock, K. L., Goldberg, A. L., Doherty, P. C., & Tonegawa, S. (1994) · Immunity · doi:10.1016/1074-7613(94)90043-4 · Cited by 447
Cited by
Enhancement of proteasome activity by a small-molecule inhibitor of USP14
Lee, B.-H., Lee, M. J., Park, S., Oh, D.-C., Elsasser, S., Chen, P.-C., Gartner, C., Dimova, N., Hanna, J., Gygi, S. P., et al. (2010) · Nature · doi:10.1038/nature09299 · Cited by 893
Genome-wide association study identifies susceptibility loci for IgA nephropathy
Gharavi, A. G., Kiryluk, K., Choi, M., Li, Y., Hou, P., Xie, J., Sanna-Cherchi, S., Men, C. J., Julian, B. A., Wyatt, R. J., et al. (2011) · Nature Genetics · doi:10.1038/ng.787 · Cited by 624
Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets
Bedford, L., Lowe, J., Dick, L. R., Mayer, R. J., & Brownell, J. E. (2011) · Nature Reviews Drug Discovery · doi:10.1038/nrd3321 · Cited by 563
“Furthermore, a number of selective inhibitors of the chymotrypsin-like subunit of the immunoproteasome have been reported, including PR957 (REF. 107) and IPSI-001 (REF. 108 ).”
BackgroundProteasome Inhibitors: An Expanding Army Attacking a Unique Target
Kisselev, A. F., van der Linden, W. A., & Overkleeft, H. S. (2012) · Chemistry & Biology · doi:10.1016/j.chembiol.2012.01.003 · Cited by 527
Targeting the ubiquitin-proteasome pathway to overcome anti-cancer drug resistance
Narayanan, S., Cai, C.-Y., Assaraf, Y. G., Guo, H.-Q., Cui, Q., Wei, L., Huang, J.-J., Ashby, C. R., & Chen, Z.-S. (2020) · Drug Resistance Updates · doi:10.1016/j.drup.2019.100663 · Cited by 332
The immunoproteasome in antigen processing and other immunological functions
Basler, M., Kirk, C. J., & Groettrup, M. (2013) · Current Opinion in Immunology · doi:10.1016/j.coi.2012.11.004 · Cited by 249
Self-citationReactive glia show increased immunoproteasome activity in Alzheimer’s disease
Orre, M., Kamphuis, W., Dooves, S., Kooijman, L., Chan, E. T., Kirk, C. J., Dimayuga Smith, V., Koot, S., Mamber, C., Jansen, A. H., et al. (2013) · Brain · doi:10.1093/brain/awt083 · Cited by 180
Self-citationThe Proteasome in Modern Drug Discovery: Second Life of a Highly Valuable Drug Target
Cromm, P. M., & Crews, C. M. (2017) · ACS Central Science · doi:10.1021/acscentsci.7b00252 · Cited by 136
Learning from the Proteasome How To Fine-Tune Cancer Immunotherapy
Vigneron, N., Abi Habib, J., & Van den Eynde, B. J. (2017) · Trends in Cancer · doi:10.1016/j.trecan.2017.07.007 · Cited by 33
Metadata
- Authors
- Muchamuel, T., Basler, M., Aujay, M. A., Suzuki, E., Kalim, K. W., Lauer, C., Sylvain, C., Ring, E. R., Shields, J., Jiang, J., Shwonek, P., Parlati, F., Demo, S. D., Bennett, M. K., Kirk, C. J., & Groettrup, M.
- Venue
- Nature Medicine
- Published
- 2009-06-14
- Volume
- 15
- Issue
- 7
- Pages
- 781-787
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W1974010669
- Cited by
- 599
- References
- 36
- FWCI
- 13.56
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
