A human memory T cell subset with stem cell–like properties
Gattinoni, Luca, Lugli, Enrico, Ji, Yun, Pos, Zoltan, Paulos, Chrystal M, Quigley, Máire F, Almeida, Jorge R, Gostick, Emma +9 more·2011·Nature Medicine
DOI 10.1038/nm.2446
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<sup>+</sup>
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- Reassessing target antigens for adoptive T-cell therapyChristian S. Hinrichs, Nicholas P. Restifo · 2013 · Nature Biotechnology
- Fine-tuning the CAR spacer improves T-cell potencyNorihiro Watanabe, Pradip Bajgain, Sujita Sukumaran, Salma Ansari, Helen Elisabeth Heslop, Cliona M. Rooney, Malcolm K. Brenner, Ann Marie Leen, Juan F. Vera · 2016 · OncoImmunology
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- The function and dysfunction of memory CD 8+ T cells in tumor immunityJames L. Reading, Felipe Gálvez‐Cancino, Charles Swanton, Álvaro Lladser, Karl S. Peggs, Sergio A. Quezada · 2018 · Immunological Reviews
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- CAR–T cells and solid tumors: tuning T cells to challenge an inveterate foeDavid Edward Gilham, Reno Debets, Martin A. Pulè, Robert E. Hawkins, Hinrich Abken · 2012 · Trends in Molecular Medicine
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