Metabolic surgery for type 2 diabetes
Abstract
Clinicians note that bariatric operations can dramatically resolve type 2 diabetes, often before and out of proportion to postoperative weight loss. Now two randomized controlled trials formally show superior results from surgical compared with medical diabetes care, including among only mildly obese patients. The concept of 'metabolic surgery' to treat diabetes has taken a big step forward.
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Many lines of evidence demonstrate glycemic benefits of RYGB independent of weight, including changes in β-cell function.
“However, many lines of evidence demonstrate glycemic benefits independent of weight ( 77 ), including changes in β-cell function ( 78 ).”
From β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment (2014) · cites this paper as [77]
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- Authors
- Cummings, D. E.
- Affiliations
- University of Washington (US)
- Corresponding author
- Cummings, David E
- Venue
- Nature Medicine
- Published
- 2012-05
- Volume
- 18
- Issue
- 5
- Pages
- 656-658
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W2041467198
- Cited by
- 31
- References
- 17
- Citations by year
- 2023: 1 · 2021: 1 · 2020: 1 · 2019: 2 · 2018: 2 · 2016: 2 · 2015: 2 · 2014: 9 · 2013: 10 · 2012: 1
- FWCI
- 7.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Surgery › Minimally Invasive Surgical Techniques
- Keywords
- metabolic surgery, type 2 diabetes, bariatric surgery, diabetes remission, weight loss, obesity, surgical versus medical treatment, randomized controlled trials
- MeSH terms
- Anastomosis, Roux-en-Y, Diabetes Mellitus, Type 2, Humans, Body Mass Index, Randomized Controlled Trials as Topic, Bariatric Surgery
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