CSF-1R inhibition alters macrophage polarization and blocks glioma progression

Pyonteck, Stephanie M, Akkari, Leila, Schuhmacher, Alberto J, Bowman, Robert L, Sevenich, Lisa, Quail, Daniela F, Olson, Oakley C, Quick, Marsha L +12 more·2013·Nature Medicine

Cited by (1,005)

Items 101–200 of 1,005

  1. Targeting Macrophages in Cancer: From Bench to Bedside
    Ashleigh R. Poh, Matthias Ernst · 2018 · Frontiers in Oncology
  2. Big opportunities for small molecules in immuno-oncology
    Jerry L. Adams, James F . Smothers, Roopa Srinivasan, Axel Hoos · 2015 · Nature Reviews Drug Discovery
  3. The role of tumor-associated macrophages (TAMs) in tumor progression and relevant advance in targeted therapy
    Yang, Qiyao, Guo, Ningning, Zhou, Yi, Chen, Jiejian, Wei, Qichun, Han, Min · 2020 · Acta Pharmaceutica Sinica B
  4. M1 Macrophage-Derived Nanovesicles Potentiate the Anticancer Efficacy of Immune Checkpoint Inhibitors
    Yeon Woong Choo, Mikyung Kang, Han Young Kim, Jin Han, Seokyung Kang, Ju‐Ro Lee, Gun‐Jae Jeong, Sung Pil Kwon, Seuk Young Song, Seokhyeong Go et al. · 2018 · ACS Nano
  5. Bidirectional Microglia–Neuron Communication in Health and Disease
    Szepesi, Zsuzsanna, Manouchehrian, Oscar, Bachiller, Sara, Deierborg, Tomas · 2018 · Frontiers in Cellular Neuroscience
  6. A fate worse than death: apoptosis as an oncogenic process
    Ichim, Gabriel, Tait, Stephen W. G. · 2016 · Nature Reviews Cancer
  7. Targeting cancer with kinase inhibitors
    Stefan David Gross, Rami Rahal, Nicolas Stransky, Christoph Lengauer, Klaus P. Hoeflich · 2015 · Journal of Clinical Investigation
  8. Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis
    Nielsen, Sebastian R., Quaranta, Valeria, Linford, Andrea, Emeagi, Perpetua, Rainer, Carolyn, Santos, Almudena, Ireland, Lucy, Sakai, Takao, Sakai, Keiko, Kim, Yong-Sam et al. · 2016 · Nature Cell Biology
  9. Tumour‐associated macrophages act as a slow‐release reservoir of nano‐therapeutic Pt(IV) pro‐drug
    Miller, Miles A., Zheng, Yao-Rong, Gadde, Suresh, Pfirschke, Christina, Zope, Harshal, Engblom, Camilla, Kohler, Rainer H., Iwamoto, Yoshiko, Yang, Katherine S., Askevold, Bjorn et al. · 2015 · Nature Communications
  10. Immune Microenvironment in Glioblastoma Subtypes
    Zhihong Chen, Dolores Hambardzumyan · 2018 · Frontiers in Immunology
  11. Tumor Microenvironment and Differential Responses to Therapy
    Hirata, Eishu, Sahai, Erik · 2017 · Cold Spring Harbor Perspectives in Medicine
  12. Macrophages and microglia in glioblastoma: heterogeneity, plasticity, and therapy
    Fatima Khan, Lizhi Pang, Madeline Dunterman, Maciej S. Lesniak, Amy B. Heimberger, Peiwen Chen · 2023 · Journal of Clinical Investigation
  13. Paclitaxel Reduces Tumor Growth by Reprogramming Tumor-Associated Macrophages to an M1 Profile in a TLR4-Dependent Manner
    Wanderley, Carlos W., Colón, David F., Luiz, João Paulo M., Oliveira, Francisco F., Viacava, Paula R., Leite, Caio A., Pereira, Janaina A., Silva, Camila M., Silva, Cassia R., Silva, Rangel L. et al. · 2018 · Cancer Research
  14. Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade
    Zhu, Ying, Yang, Jing, Xu, Da, Gao, Xiao-Mei, Zhang, Ze, Hsu, Jennifer L, Li, Chia-Wei, Lim, Seung-Oe, Sheng, Yuan-Yuan, Zhang, Yu et al. · 2019 · Gut
  15. Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1
    Frank Szulzewsky, Andreas Pelz, Xi Feng, Michael Synowitz, Darko S. Markovic, Thomas Langmann, Inge R. Holtman, Xi Wang, Bart J. L. Eggen, H. W. G. M. Boddeke et al. · 2015 · PLoS ONE
  16. Single-cell spatial immune landscapes of primary and metastatic brain tumours
    Elham Karimi, Miranda W. Yu, Sarah M. Maritan, Lucas J. M. Perus, Morteza Rezanejad, Mark Sorin, Matthew Dankner, Parvaneh Fallah, Samuel Doré, Dongmei Zuo et al. · 2023 · Nature
  17. Understanding the immunosuppressive microenvironment of glioma: mechanistic insights and clinical perspectives
    Hao Lin, Chaxian Liu, An-Kang Hu, Duanwu Zhang, Hui Yang, Ying Qing Mao · 2024 · Journal of Hematology & Oncology
  18. Contribution to Tumor Angiogenesis From Innate Immune Cells Within the Tumor Microenvironment: Implications for Immunotherapy
    Adriana Albini, Antonino Bruno, Douglas McClain Noonan, Lorenzo Mortara · 2018 · Frontiers in Immunology
  19. Known and novel roles of the MET oncogene in cancer: a coherent approach to targeted therapy
    Paolo Maria Comoglio, Livio Trusolino, Carla Boccaccio · 2018 · Nature reviews. Cancer
  20. CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8+T cells
    Debbie C. Strachan, Brian Ruffell, Yoko A. Oei, Mina J. Bissell, Lisa M. Coussens, Nancy Pryer, Dylan Daniel · 2013 · OncoImmunology
  21. Methotrexate chemotherapy induces persistent tri-glial dysregulation that underlies chemotherapy-related cognitive impairment
    Gibson, Erin M., Nagaraja, Surya, Ocampo, Alfonso, Tam, Lydia T., Wood, Lauren S., Pallegar, Praveen N., Greene, Jacob J., Geraghty, Anna C., Goldstein, Andrea K., Ni, Lijun et al. · 2019 · Cell
  22. Targeting tumor-associated macrophages and granulocytic myeloid-derived suppressor cells augments PD-1 blockade in cholangiocarcinoma
    Emilien J. Loeuillard, Jingchun Yang, EeeLN H. Buckarma, Juan Wang, Yuanhang Liu, Caitlin B. Conboy, Kevin D. Pavelko, Ying Li, Daniel R. O’Brien, Chen Wang et al. · 2020 · Journal of Clinical Investigation
  23. Tissue macrophages: origin, heterogenity, biological functions, diseases and therapeutic targets
    Guan, Fan, Wang, Ruixuan, Yi, Zhenjie, Luo, Peng, Liu, Wanyao, Xie, Yao, Liu, Zaoqu, Xia, Zhiwei, Zhang, Hao, Cheng, Quan · 2025 · Signal Transduction and Targeted Therapy
  24. Targeting cancer-promoting inflammation — have anti-inflammatory therapies come of age?
    Jiajie Hou, Michael Karin, Beicheng Sun · 2021 · Nature Reviews Clinical Oncology
  25. Tumor-Associated Macrophages: Implications in Cancer Immunotherapy
    Amy J. Petty, Yiping Yang · 2017 · Immunotherapy
  26. Harnessing tumor‐associated macrophages as aids for cancer immunotherapy
    Li, Xiaolei, Liu, Rui, Su, Xiao, Pan, Yongsha, Han, Xiaofeng, Shao, Changshun, Shi, Yufang · 2019 · Molecular Cancer
  27. Pediatric high-grade glioma: biologically and clinically in need of new thinking
    Chris Jones, Matthias A. Karajannis, David Jones, Mark W. Kieran, Michelle Monje, Suzanne J. Baker, Oren Josh Becher, Yoon‐Jae Cho, Nalin M. Gupta, Cynthia E Hawkins et al. · 2016 · Neuro-Oncology
  28. Emerging Roles for CSF-1 Receptor and its Ligands in the Nervous System
    Violeta Chiţu, Şölen Gökhan, Sayan Nandi, Mark F. Mehler, E. Richard Stanley · 2016 · Trends in Neurosciences
  29. Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion
    Ester Gangoso, Benjamin Southgate, Leanne Bradley, Stefanie Lehr, Felipe Gálvez‐Cancino, Niamh McGivern, Esra Güç, Chantriolnt-Andreas Kapourani, Adam Byron, Kirsty M. Ferguson et al. · 2021 · Cell
  30. Immune profiling of human tumors identifies CD73 as a combinatorial target in glioblastoma
    Goswami, Sangeeta, Walle, Thomas, Cornish, Andrew E., Basu, Sreyashi, Anandhan, Swetha, Fernandez, Irina, Vence, Luis, Blando, Jorge, Zhao, Hao, Yadav, Shalini Singh et al. · 2020 · Nature Medicine
  31. Dual roles and therapeutic targeting of tumor-associated macrophages in tumor microenvironments
    Jiasheng Xu, Lei Ding, Jianfeng Mei, Yeting Hu, Xiangxing Kong, Siqi Dai, Tongtong Bu, Qian Xiao, Kefeng Ding · 2025 · Signal Transduction and Targeted Therapy
  32. Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors
    He, Lizhi, Jhong, Jhih-Hua, Chen, Qi, Huang, Kai-Yao, Strittmatter, Karin, Kreuzer, Johannes, DeRan, Michael, Wu, Xu, Lee, Tzong-Yi, Slavov, Nikolai et al. · 2021 · Cell Reports
  33. SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions
    Ferdinando Pucci, Christopher Garris, Charles Pin‐Kuang Lai, Andita Newton, Christina Pfirschke, Camilla Engblom, David Álvarez, Melissa M. Sprachman, Charles Lee Evavold, Angela M. Magnuson et al. · 2016 · Science
  34. Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype
    Timothy N. Phoenix, Deanna M. Patmore, Scott H. Boop, Nidal Boulos, Megan O. Jacus, Yogesh T. Patel, Martine F. Roussel, David Finkelstein, Liliana Christova Goumnerova, Sébastien Perreault et al. · 2016 · Cancer Cell
  35. Roles of macrophages in tumor development: a spatiotemporal perspective
    Mathilde Bied, William W. Ho, Florent Ginhoux, Camille Blériot · 2023 · Cellular and Molecular Immunology
  36. CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy
    Alba Rodríguez-García, Rachel C. Lynn, Mathilde Poussin, Monika A. Eiva, Lauren C. Shaw, Roddy S. O’Connor, Nicholas G. Minutolo, Victoria Casado‐Medrano, Gonzalo López, Takami Matsuyama et al. · 2021 · Nature Communications
  37. Immunosuppressive mechanisms in glioblastoma: Fig. 1.
    Edjah Kweku-Ebura Nduom, Michael Weller, Amy B. Heimberger · 2015 · Neuro-Oncology
  38. Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth
    Yu Shi, Yi-Fang Ping, Wenchao Zhou, Zhi Cheng He, Cong Chen, Baishijiao Bian, Lin Zhang, Lu Chen, Xun Lan, Xian Chao Zhang et al. · 2017 · Nature Communications
  39. Major pathways involved in macrophage polarization in cancer
    Clément Kerneur, Carla Eliana Cano, Daniel Olive · 2022 · Frontiers in Immunology
  40. Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma
    Peiwen Chen, Di Zhao, Jun Li, Xin Liang, Jiexi Li, Andrew H. Chang, Verlene K. Henry, Zhengdao Lan, Denise J. Spring, Ganesh Rao et al. · 2019 · Cancer Cell
  41. The role of tumor-associated macrophages in gastric cancer development and their potential as a therapeutic target
    Valentina Gambardella, Josefa Castillo, Noelia Tarazona, Francisco Gimeno-Valiente, Carolina Martínez‐Ciarpaglini, Manuel Cabeza-Segura, Susana Roselló, D. Roda, Marisol Huerta, Andrès M.R. Cervantes et al. · 2020 · Cancer Treatment Reviews
  42. Molecular-Targeted Immunotherapeutic Strategy for Melanoma via Dual-Targeting Nanoparticles Delivering Small Interfering RNA to Tumor-Associated Macrophages
    Yuan Qian, Sha Qiao, Yanfeng Dai, Guoqiang Xu, Bolei Dai, Lisen Lu, Xiang Min Yu, Qingming Luo, Zhihong Zhang · 2017 · ACS Nano
  43. Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms
    Ik Sun Kim, Yang Gao, Thomas Welte, Hai Wang, Jun Liu, Mahnaz Janghorban, Kuanwei Sheng, Yichi Niu, Amit Goldstein, Na Zhao et al. · 2019 · Nature Cell Biology
  44. Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages
    S. Arlauckas, Seth B. Garren, Christopher S. Garris, R. Kohler, Juhyun Oh, M. Pittet, R. Weissleder · 2018 · Theranostics
  45. The Role of Macrophages in Cancer Development and Therapy
    Cendrowicz, Ewa, Sas, Zuzanna, Bremer, Edwin, Rygiel, Tomasz P. · 2021 · Cancers
  46. Anti-CD47 Treatment Stimulates Phagocytosis of Glioblastoma by M1 and M2 Polarized Macrophages and Promotes M1 Polarized Macrophages In Vivo
    Michael Zhang, Gregor Hütter, Suzana Assad Kahn, Tej Deepak Azad, Sharareh Gholamin, Chelsea Y. Xu, Jie Liu, Achal Singh Achrol, Chase Richard, Pia Sommerkamp et al. · 2016 · PLoS ONE
  47. Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance
    Leila Akkari, Robert L. Bowman, Jeremy Tessier, Florian Klemm, Shanna M. Handgraaf, Marnix H. P. de Groot, Daniela F. Quail, Lucie Tillard, Jules Gadiot, Jason T. Huse et al. · 2020 · Science Translational Medicine
  48. Tumor microenvironment in glioblastoma: Current and emerging concepts
    Pratibha Sharma, Ashley Aaroe, Jiyong Liang, Vinay K. Puduvalli · 2023 · Neuro-Oncology Advances
  49. The Promise of Targeting Macrophages in Cancer Therapy
    J. Martin Brown, Lawrence David Recht, Samuel Strober · 2017 · Clinical Cancer Research
  50. Brain Tumor Microenvironment and Host State: Implications for Immunotherapy
    William H. Tomaszewski, Luis A Sanchez-Perez, Thomas Frank Gajewski, John Howard Sampson · 2019 · Clinical Cancer Research
  51. Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9
    Ernesto Rodríguez, Kelly Boelaars, Kari Brown, R. J. Eveline Li, Laura J. W. Kruijssen, Sven C. M. Bruijns, Thomas van Ee, Sjoerd T. T. Schetters, Matheus H. W. Crommentuijn, Joost C. van der Horst et al. · 2021 · Nature Communications
  52. Tumor-associated macrophages in cancer: recent advancements in cancer nanoimmunotherapies
    Nisha Kumari, Seung Hong Choi · 2022 · Journal of Experimental & Clinical Cancer Research
  53. Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages
    Peterson, Teresa E., Kirkpatrick, Nathaniel D., Huang, Yuhui, Farrar, Christian T., Marijt, Koen A., Kloepper, Jonas, Datta, Meenal, Amoozgar, Zohreh, Seano, Giorgio, Jung, Keehoon et al. · 2016 · Proceedings of the National Academy of Sciences
  54. 3D‐Bioprinted Mini‐Brain: A Glioblastoma Model to Study Cellular Interactions and Therapeutics
    Marcel Alexander Heinrich, Ruchi Bansal, Twan Lammers, Yu Shrike Zhang, Raymond Michel Schiffelers, Jai Prakash · 2019 · Advanced Materials
  55. Macrophage Metabolism As Therapeutic Target for Cancer, Atherosclerosis, and Obesity
    Xenia Geeraerts, Evangelia Bolli, Sarah‐Maria Fendt, Jo A. Van Ginderachter · 2017 · Frontiers in Immunology
  56. Immunity, Hypoxia, and Metabolism–the Ménage à Trois of Cancer: Implications for Immunotherapy
    Riera-Domingo, Carla, Audigé, Annette, Granja, Sara, Cheng, Wan-Chen, Ho, Ping-Chih, Baltazar, Fátima, Stockmann, Christian, Mazzone, Massimiliano · 2020 · Physiological Reviews
  57. T cell–induced CSF1 promotes melanoma resistance to PD1 blockade
    Neubert, Natalie J., Schmittnaegel, Martina, Bordry, Natacha, Nassiri, Sina, Wald, Noémie, Martignier, Christophe, Tillé, Laure, Homicsko, Krisztian, Damsky, William, Maby-El Hajjami, Hélène et al. · 2018 · Science Translational Medicine
  58. Glioblastoma at the crossroads: current understanding and future therapeutic horizons
    Shilpi Singh, Devanjan Dey, Debashis Barik, Iteeshree Mohapatra, Stefan Kim, Mayur Sharma, Sujata Prasad, Peize Wang, Amar Ranjan Singh, Gatikrushna Singh · 2025 · Signal Transduction and Targeted Therapy
  59. Therapeutic targeting of tumour myeloid cells
    Barry, Simon T., Gabrilovich, Dmitry I., Sansom, Owen J., Campbell, Andrew D., Morton, Jennifer P. · 2023 · Nature Reviews Cancer
  60. The roles of macrophages and microglia in multiple sclerosis and experimental autoimmune encephalomyelitis
    Fengna Chu, Mingchao Shi, Chao Zheng, Donghui Shen, Jie Zhu, Xiangyu Zheng, Li Cui · 2018 · Journal of Neuroimmunology
  61. Current Strategies to Target Tumor-Associated-Macrophages to Improve Anti-Tumor Immune Responses
    Clément Anfray, Aldo Ummarino, Fernando Torres Andón, P. Allavena · 2019 · Cells
  62. The immune system and cancer evasion strategies: therapeutic concepts
    Muenst, S., Läubli, H., Soysal, S. D., Zippelius, A., Tzankov, A., Hoeller, S. · 2016 · Journal of Internal Medicine
  63. Molecular Repolarisation of Tumour-Associated Macrophages
    Floris J. van Dalen, Marleen H. M. E. van Stevendaal, Felix L. Fennemann, Martijn Verdoes, Olga Ilina · 2018 · Molecules
  64. Tumor infiltrating immune cells in gliomas and meningiomas.
    P. Domingues, M. González-Tablas, Á. Otero, Daniel Pascual, David Miranda, Laura Ruíz, P. Sousa, J. Ciudad, J. Gonçalves, M. C. Lopes et al. · 2016 · Brain, behavior, and immunity
  65. Integrin CD11b activation drives anti-tumor innate immunity
    Michael C. Schmid, Samia Q. Khan, Megan M. Kaneda, Paulina Pathria, Ryan M. Shepard, Tiani L. Louis, Sudarshan Anand, Gyunghwi Woo, Christopher J. Leem, Mohd Hafeez Faridi et al. · 2018 · Nature Communications
  66. Microglia–blood vessel interactions: a double-edged sword in brain pathologies
    Dudvarski Stankovic, Nevenka, Teodorczyk, Marcin, Ploen, Robert, Zipp, Frauke, Schmidt, Mirko H. H. · 2016 · Acta Neuropathologica
  67. Macrophages as Key Drivers of Cancer Progression and Metastasis
    S. R. Nielsen, Michael C. Schmid · 2017 · Mediators of Inflammation
  68. Tailoring Nanomaterials for Targeting Tumor‐Associated Macrophages
    Muhammad Ovais, Mengyu Guo, Chunying Chen · 2019 · Advanced Materials
  69. Microglia/Brain Macrophages as Central Drivers of Brain Tumor Pathobiology
    David H. Gutmann, Helmut Kettenmann · 2019 · Neuron
  70. A review of glioblastoma immunotherapy
    Ravi Teja Medikonda, Gavin P. Dunn, Maryam Rahman, Peter Edward Fecci, Michael K. Lim · 2020 · Journal of Neuro-Oncology
  71. Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47−mediated ‘don’t-eat-me’ signal
    Mingen Liu, Roddy S. O’Connor, Sophie Trefely, Kathleen L. Graham, Nathaniel W. Snyder, Gregory Lawrence Beatty · 2019 · Nature Immunology
  72. Intratumoral heterogeneity in glioblastoma: don't forget the peritumoral brain zone
    Jean-michel Lemée M. D, Anne Clavreul, Philippe Meneï · 2015 · Neuro-Oncology
  73. When Immune Cells Turn Bad—Tumor-Associated Microglia/Macrophages in Glioma
    Saskia Roesch, Carmen Rapp, Steffen Dettling, Christel C. Herold‐Mende · 2018 · International Journal of Molecular Sciences
  74. Macrophages: The Road Less Traveled, Changing Anticancer Therapy
    Jennifer L. Guerriero · 2018 · Trends in Molecular Medicine
  75. Hypoxic niches attract and sequester tumor-associated macrophages and cytotoxic T cells and reprogram them for immunosuppression
    Anirudh Sattiraju, Sangjo Kang, Bruno Giotti, Zhihong Chen, Valerie J. Marallano, Concetta Brusco, Aarthi Ramakrishnan, Li Shen, Alexander M. Tsankov, Dolores Hambardzumyan et al. · 2023 · Immunity
  76. Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates
    Doloff, Joshua C., Veiseh, Omid, Vegas, Arturo J., Tam, Hok Hei, Farah, Shady, Ma, Minglin, Li, Jie, Bader, Andrew, Chiu, Alan, Sadraei, Atieh et al. · 2017 · Nature Materials
  77. Turning ecology and evolution against cancer
    Kirill S. Korolev, João B. Xavier, Jeff Gore · 2014 · Nature reviews. Cancer
  78. Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α
    Qirui Wang, Zhenqiang He, Menggui Huang, Tianrun Liu, Yanling Wang, Haineng Xu, Hao Duan, Peihong Ma, Lin Zhang, Scott S. Zamvil et al. · 2018 · Nature Communications
  79. TNF Counterbalances the Emergence of M2 Tumor Macrophages
    Franz Kratochvill, Geoffrey A. M. Neale, Jessica M. Haverkamp, Lee-Ann Van de Velde, Amber M. Smith, Daisuke Kawauchi, Justina D. McEvoy, Martine F. Roussel, Michael A. Dyer, Joseph E. Qualls et al. · 2015 · Cell Reports
  80. Redirecting tumor-associated macrophages to become tumoricidal effectors as a novel strategy for cancer therapy
    Xiang Zheng, Kati Turkowski, Javier Mora, B. Brüne, W. Seeger, A. Weigert, R. Savai · 2017 · OncoTarget
  81. Dual prognostic significance of tumour-associated macrophages in human pancreatic adenocarcinoma treated or untreated with chemotherapy
    Giuseppe Di Caro, Nina Cortese, Giovanni Francesco Castino, Fabio Grizzi, Francesca Gavazzi, Cristina Ridolfi, Giovanni Luigi Capretti, Rossana Mineri, Jelena Todoric, Alessandro Zerbi et al. · 2015 · Gut
  82. Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies
    Ana Rita Pombo Antunes, Isabelle Scheyltjens, Johnny Duerinck, Bart Neyns, Kiavash Movahedi, Jo A. Van Ginderachter · 2020 · eLife
  83. Black phosphorus-based photothermal therapy with aCD47-mediated immune checkpoint blockade for enhanced cancer immunotherapy
    Zhongjian Xie, Minhua Peng, Ruitao Lu, Xiangying Meng, Weiyuan Liang, Zhongjun Li, Meng Qiu, Bin Zhang, Guohui Nie, Ni Xie et al. · 2020 · Light Science & Applications
  84. CSF1/CSF1R Signaling Inhibitor Pexidartinib (PLX3397) Reprograms Tumor-Associated Macrophages and Stimulates T-cell Infiltration in the Sarcoma Microenvironment
    Tomohiro Fujiwara, Mohamed A. Yakoub, Andrew Chandler, Alexander B. Christ, Guangli Yang, Ouathek Ouerfelli, Vinagolu K. Rajasekhar, Aki Yoshida, Hiroya Kondo, Toshiaki Hata et al. · 2021 · Molecular Cancer Therapeutics
  85. Molecular Mechanisms of Treatment Resistance in Glioblastoma
    Alexander C. Ou, W.K. Alfred Yung, Nazanin Majd · 2020 · International Journal of Molecular Sciences
  86. Estrogen Receptor Signaling in the Immune System
    Binita Chakraborty, Jovita K. Byemerwa, Taylor Krebs, Felicia Lim, Ching‐yi Chang, Donald Patrick McDonnell · 2022 · Endocrine Reviews
  87. Cancer Inflammation and Cytokines
    Maria Rosaria Galdiero, Gianni Marone, Alberto Mantovani · 2017 · Cold Spring Harbor Perspectives in Biology
  88. Immune Evasion Strategies of Glioblastoma
    Seyed‐Mostafa Razavi, Karen E. Lee, Benjamin E. Jin, Parvir S. Aujla, Sharareh Gholamin, Gordon Li · 2016 · Frontiers in Surgery
  89. Challenges and new technologies in adoptive cell therapy
    Pengchao Zhang, Guizhong Zhang, Xiaochun Wan · 2023 · Journal of Hematology & Oncology
  90. Cancer Stem Cell-Specific Scavenger Receptor CD36 Drives Glioblastoma Progression
    James S. Hale, Balint Otvos, Maksim Sinyuk, Alvaro G. Alvarado, Masahiro Hitomi, Kevin Stoltz, Qiulian Wu, William A. Flavahan, Bruce S. Levison, Mette L. Johansen et al. · 2014 · Stem Cells
  91. Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity
    Baer, Caroline, Squadrito, Mario Leonardo, Laoui, Damya, Thompson, Danielle, Hansen, Sarah K., Kiialainen, Anna, Hoves, Sabine, Ries, Carola H., Ooi, Chia-Huey, De Palma, Michele · 2016 · Nature Cell Biology
  92. CSF-1–dependant donor-derived macrophages mediate chronic graft-versus-host disease
    Kylie A. Alexander, Ryan P Flynn, Katie E. Lineburg, Rachel D. Kuns, Bianca E. Teal, Stuart D. Olver, Mary Lor, Neil C. Raffelt, Motoko Koyama, Lucie Leveque et al. · 2014 · Journal of Clinical Investigation
  93. TH2-Polarized CD4+ T Cells and Macrophages Limit Efficacy of Radiotherapy
    Stephen Lawrence Shiao, Brian Ruffell, David G. DeNardo, Bruce Faddegon, Catherine C. Park, Lisa M. Coussens · 2015 · Cancer Immunology Research
  94. HBEGF+ macrophages in rheumatoid arthritis induce fibroblast invasiveness
    David Kuo, Jennifer Ding, I. Cohn, Fan Zhang, Kevin Wei, Deepak A. Rao, C. Rozo, Upneet K. Sokhi, Sara Shanaj, D. Oliver et al. · 2019 · Science Translational Medicine
  95. Tumor-associated macrophages: role in cancer development and therapeutic implications
    Arash Salmaninejad, Saeed Farajzadeh Valilou, Arash Soltani, Sepideh Ahmadi, Yousef Jafari Abarghan, Rhonda J. Rosengren, Amirhossein Sahebkar · 2019 · Cellular Oncology
  96. The M-CSF receptor in osteoclasts and beyond
    Se Hwan Mun, Peter Sang Uk Park, Kyung‐Hyun Park‐Min · 2020 · Experimental & Molecular Medicine
  97. Dual-targeting biomimetic delivery for anti-glioma activity via remodeling the tumor microenvironment and directing macrophage-mediated immunotherapy
    Pengfei Zhao, Yonghui Wang, Xuejia Kang, Aihua Wu, Weimin Yin, Yisi Tang, Jinyu Wang, Meng Zhang, Yifei Duan, Yongzhuo Huang · 2018 · Chemical Science
  98. Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion
    Balint Otvos, Daniel J. Silver, Erin E. Mulkearns-Hubert, Alvaro G. Alvarado, Soumya M. Turaga, Mia Dahl Sørensen, Patricia A. Rayman, William A. Flavahan, James S. Hale, Kevin Stoltz et al. · 2016 · Stem Cells
  99. Glioblastoma-associated microglia and macrophages: targets for therapies to improve prognosis
    Candice C. Poon, Susobhan Sarkar, Voon Wee Yong, John J. Kelly · 2017 · Brain
  100. Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors
    Lucy Ireland, Almudena Santos, Muhammad S. Ahmed, Carolyn Rainer, Sebastian Rune Nielsen, Valeria Quaranta, Ulrike Weyer-Czernilofsky, Dannielle D. Engle, Pedro Antonio Pérez-Mancera, Sarah E. Coupland et al. · 2016 · Cancer Research