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Activation and deactivation of periventricular white matter phagocytes during postnatal mouse development

Hristova, M., Cuthill, D., Zbarsky, V., Acosta‐Saltos, A., Wallace, A. S., Blight, K., Buckley, S. M. K., Peebles, D., Heuer, H., Waddington, S. N., et al. (2009) · Glia · doi:10.1002/glia.20896 · Cited by 105 · see citing works

Innate immune functions of microglia isolated from human glioma patients

Hussain, S. F., Yang, D. S., Suki, D., Grimm, E. A., & Heimberger, A. B. (2006) · Journal of Translational Medicine · doi:10.1186/1479-5876-4-15 · Cited by 105 · see citing works

Randomized phase 1b trial of MOR103, a human antibody to GM-CSF, in multiple sclerosis

Constantinescu, C. S., Asher, A., Fryze, W., Kozubski, W. P., Wagner, F. D., Aram, J., Tănăsescu, R., Korolkiewicz, R. P., Dirnberger‐Hertweck, M., Steidl, S., et al. (2015) · Neurology Neuroimmunology & Neuroinflammation · doi:10.1212/nxi.0000000000000117 · Cited by 105 · see citing works

Partial volume effect-corrected FDG PET and grey matter volume loss in patients with mild Alzheimer’s disease

Samuraki, M., Matsunari, I., Chen, W.-P., Yajima, K., Yanase, D., Fujikawa, A., Takeda, N., Nishimura, S., Matsuda, H., & Yamada, M. (2007) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-007-0454-x · Cited by 92 · see citing works

p38 MAPK inhibitors attenuate pro-inflammatory cytokine production and the invasiveness of human U251 glioblastoma cells

Yeung, Y.-T., Bryce, N. S., Adams, S., Braidy, N., Konayagi, M., McDonald, K., Teo, C., Guillemin, G., Grewal, T., & Munoz, L. (2012) · Journal of Neuro-Oncology · doi:10.1007/s11060-012-0875-7 · Cited by 90 · see citing works

Microglia

Soulet, D., & Rivest, S. (2008) · Current Biology · doi:10.1016/j.cub.2008.04.047 · Cited by 90 · see citing works

Differences in expression of junctional adhesion molecule-A and β-catenin in multiple sclerosis brain tissue: increasing evidence for the role of tight junction pathology

Padden, M., Leech, S., Craig, B., Kirk, J., Brankin, B., & McQuaid, S. (2006) · Acta Neuropathologica · doi:10.1007/s00401-006-0145-x · Cited by 86 · see citing works

Microglia is a Key Player in the Reduction of Stroke Damage Promoted by the New Antithrombotic Agent Ticagrelor

Gelosa, P., Lecca, D., Fumagalli, M., Wypych, D., Pignieri, A., Cimino, M., Verderio, C., Enerbäck, M., Nikookhesal, E., Tremoli, E., et al. (2014) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2014.45 · Cited by 85 · see citing works

Microglial activation state exerts a biphasic influence on brain endothelial cell proliferation by regulating the balance of TNF and TGF-β1

Welser, J. V., Li, L., & Milner, R. (2010) · Journal of Neuroinflammation · doi:10.1186/1742-2094-7-89 · Cited by 79 · see citing works

EGFL7 ligates αvβ3 integrin to enhance vessel formation

Nikolić, I., Stanković, N. D., Bicker, F., et al. (2013) · Blood · doi:10.1182/blood-2011-11-394882 · Cited by 77 · see citing works

Embryonic CNS macrophages and microglia do not stem from circulating, but from extravascular precursors.

Kurz, H., & Christ, B. (1998) · PubMed · Cited by 69 · see citing works

Fractalkine‐CX3CR1 axis regulates tumor cell cycle and deteriorates prognosis after radical resection for hepatocellular carcinoma

Matsubara, T., Ono, T., Yamanoi, A., et al. (2007) · Journal of Surgical Oncology · doi:10.1002/jso.20642 · Cited by 69 · see citing works

Glatiramer Acetate Modulates TNF-α and IL-10 Secretion in Microglia and Promotes Their Phagocytic Activity

Pul, R., Moharregh-Khiabani, D., Škuljec, J., Skripuletz, T., Garde, N., Voß, E. V., & Stangel, M. (2010) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-010-9248-1 · Cited by 67 · see citing works

Novel Molecular Insights into Classical and Alternative Activation States of Microglia as Revealed by Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)-based Proteomics*

Bell‐Temin, H., Culver‐Cochran, A. E., Chaput, D., Carlson, C., Kuehl, M. N., Burkhardt, B. R., Bickford, P. C., Liu, B., & Stevens, S. M. (2015) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m115.053926 · Cited by 58 · see citing works

Increased microglia proliferation separates pilocytic astrocytomas from diffuse astrocytomas: a double labeling study

Klein, R., & Roggendorf, W. (2001) · Acta Neuropathologica · doi:10.1007/s004010000286 · Cited by 58 · see citing works

Myeloid Cells in Alzheimer's Disease: Culprits, Victims or Innocent Bystanders?

Meyer‐Luehmann, M., & Prinz, M. (2015) · Trends in Neurosciences · doi:10.1016/j.tins.2015.08.011 · Cited by 57 · see citing works

Stage-Specific Immune Dysregulation in Multiple Sclerosis

Segal, B. M. (2014) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2014.0025 · Cited by 49 · see citing works

Focal transient CNS vessel leak provides a tissue niche for sequential immune cell accumulation during the asymptomatic phase of EAE induction

Barkauskas, D. S., Dorand, R. D., Myers, J., Evans, T. A., Barkauskas, K. J., Askew, D., Purgert, R., & Huang, A. Y.-C. (2015) · Experimental Neurology · doi:10.1016/j.expneurol.2015.02.018 · Cited by 44 · see citing works

Relevance of chronic stress and the two faces of microglia in Parkinson's disease

Herrera, A. J., Espinosa-Oliva, A. M., Carrillo-Jiménez, A., Oliva-Martín, M. J., García-Revilla, J., García-Quintanilla, A., de Pablos, R. M., & Venero, J. L. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00312 · Cited by 42 · see citing works

Extensive vascular remodeling in the spinal cord of pre-symptomatic experimental autoimmune encephalomyelitis mice; increased vessel expression of fibronectin and the α5β1 integrin

Boroujerdi, A., Welser-Alves, J. V., & Milner, R. (2013) · Experimental Neurology · doi:10.1016/j.expneurol.2013.09.009 · Cited by 39 · see citing works

Lipopolysaccharide-activated microglia lower P-glycoprotein function in brain microvascular endothelial cells

Matsumoto, J., Dohgu, S., Takata, F., Nishioku, T., Sumi, N., Machida, T., Takahashi, H., Yamauchi, A., & Kataoka, Y. (2012) · Neuroscience Letters · doi:10.1016/j.neulet.2012.07.004 · Cited by 37 · see citing works

Correction: The importance of microglia in the development of the vasculature in the central nervous system

Arnold, T., & Betsholtz, C. (2013) · Vascular Cell · doi:10.1186/2045-824x-5-12 · Cited by 35 · see citing works

Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

Loh, J. S., Mak, W. Q., Tan, L. K. S., Ng, C. X., Chan, H. H., Yeow, S. H., Foo, J. B., Ong, Y. S., How, C. W., & Khaw, K. Y. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01743-1 · Cited by 1,193 · see citing works

Dual microglia effects on blood brain barrier permeability induced by systemic inflammation

Haruwaka, K., Ikegami, A., Tachibana, Y., Ohno, N., Konishi, H., Hashimoto, A., Matsumoto, M., Kato, D., Ono, R., Kiyama, H., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-13812-z · Cited by 923 · see citing works

Macrophages in health and disease

Park, M. D., Silvin, A., Ginhoux, F., & Merad, M. (2022) · Cell · doi:10.1016/j.cell.2022.10.007 · Cited by 644 · see citing works

The role of microglia in retinal neurodegeneration: Alzheimer’s disease, parkinson, and glaucoma.

Ramirez, A. I., de Hoz, R., Salobrar-Garcia, E., Salazar, J. J., Rojas, B., Ajoy, D., López-Cuenca, I., Rojas, P., Triviño, A., & Ramírez, J. M. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00214 · Cited by 466 · see citing works

Factors influencing the blood-brain barrier permeability

Zhao, Y., Gan, L., Ren, L., Lin, Y., Ma, C., & Lin, X. (2022) · Brain Research · doi:10.1016/j.brainres.2022.147937 · Cited by 291 · see citing works

Brain Barrier Breakdown as a Cause and Consequence of Neuroinflammation in Sepsis

Danielski, L. G., Giustina, A. D., Badawy, M., Barichello, T., Quevedo, J., Dal-Pizzol, F., & Petronilho, F. (2018) · Molecular Neurobiology · doi:10.1007/s12035-016-0356-7 · Cited by 182 · see citing works

Human iPSC‐derived microglia: A growing toolset to study the brain's innate immune cells

Hasselmann, J., & Blurton‐Jones, M. (2020) · Glia · doi:10.1002/glia.23781 · Cited by 145 · see citing works

Microglial priming in Alzheimer’s disease

Li, J.-W., Zong, Y., Cao, X.-P., Tan, L., & Tan, L. (2018) · Annals of Translational Medicine · doi:10.21037/atm.2018.04.22 · Cited by 122 · see citing works

Microglial Activation Damages Dopaminergic Neurons through MMP-2/-9-Mediated Increase of Blood-Brain Barrier Permeability in a Parkinson’s Disease Mouse Model

Ruan, Z., Zhang, D., Huang, R., Sun, W., Hou, L., Zhao, J., & Wang, Q. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052793 · Cited by 82 · see citing works

Gliovascular alterations in sporadic and familial Alzheimer's disease: <scp><i>APOE3</i></scp> Christchurch homozygote glioprotection

Henao‐Restrepo, J., López‐Murillo, C., Valderrama‐Carmona, P., Orozco‐Santa, N., Gomez, J., Gutiérrez‐Vargas, J., Moraga, R., Toledo, J., Littau, J. L., Härtel, S., et al. (2023) · Brain Pathology · doi:10.1111/bpa.13119 · Cited by 11 · see citing works

Alzheimer’s Disease Research Using Human Microglia

Lue, L., Beach, T. G., & Walker, D. G. (2019) · Cells · doi:10.3390/cells8080838 · Cited by 26 · see citing works

Differential Regional Vulnerability of the Brain to Mild Neuroinflammation Induced by Systemic LPS Treatment in Mice

Jung, H., Lee, H., Kim, D., Cheong, E., Hyun, Y., Yu, J., & Um, J. W. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s362006 · Cited by 31 · see citing works

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation

Voet, S., Mc Guire, C., Hagemeyer, N., Martens, A., Schroeder, A., Wieghofer, P., Daems, C., Staszewski, O., Vande Walle, L., Jordao, M. J. C., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04376-5 · Cited by 227 · see citing works

Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes

Kwon, H. S., & Koh, S.-H. (2020) · Translational Neurodegeneration · doi:10.1186/s40035-020-00221-2 · Cited by 2,595 · see citing works

Human Brain Parenchymal Microglia Express CD14 and CD45 and are Productively Infected by HIV‐1 in HIV‐1 Encephalitis

Cosenza;, M. A., Zhao;, M., Si;, Q., & Lee, S. C. (2002) · Brain Pathology · doi:10.1111/j.1750-3639.2002.tb00461.x · Cited by 238 · see citing works