Development, maintenance and disruption of the blood-brain barrier

Obermeier, Birgit, Daneman, Richard, Ransohoff, Richard M·2013·Nature Medicine

DOI 10.1038/nm.3407

Cited by (1,004)

Items 301–400 of 1,004

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Zhao, Hengli, Zhang, Xuan, Dai, Zhiqiang, Feng, Yang, Li, Qiang, Zhang, John H., Liu, Xin, Chen, Yujie, Feng, Hua · 2016 · Scientific Reports
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Yuyuan Wang, Xiuxiu Wang, Ruosen Xie, Jacobus C. Burger, Yao Tong, Shaoqin Gong · 2022 · Advanced Materials
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Zhichun Chen, Shengdi Chen, Jun Liu · 2018 · Progress in Neurobiology
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Young, Christina B., Johns, Emily, Kennedy, Gabriel, Belloy, Michael E., Insel, Philip S., Greicius, Michael D., Sperling, Reisa A., Johnson, Keith A., Poston, Kathleen L., Mormino, Elizabeth C. et al. · 2023 · Molecular Neurodegeneration
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María-Angélica Calderón-Peláez, Myriam Lucía Velandia-Romero, Leidy Y. Bastidas-Legarda, Edgar O. Beltrán, Sigrid J. Camacho-Ortega, Jaime Eduardo Castellanos · 2019 · Frontiers in Microbiology
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Elodie Pothin, Dominique Lesuisse, Pierre J. Lafaye · 2020 · Pharmaceutics
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Ying‐Chieh Wu, Tizibt Ashine Bogale, Jari Koıstınaho, Marina Pizzi, Taisia Rõlova, Arianna Bellucci · 2024 · Acta Neuropathologica
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Seungjoo Lee, Il‐Kug Kim, Jae Sung Ahn, Dong‐Cheol Woo, Sang‐Tae Kim, Sukhyun Song, Gou Young Koh, Hyung-Seok Kim, Byeong Hwa Jeon, Injune Kim · 2015 · Circulation
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Haiying Zhang, Joon Ha Park, Sony Maharjan, Jeong Ae Park, Kyu-Sung Choi, Hyojin Park, Yoonjeong Jeong, Ji Hyeon Ahn, In Hye Kim, Jae Chul Lee et al. · 2017 · Journal of Neuroinflammation
Blood brain barrier (BBB)-disruption in intracortical silicon microelectrode implants
Cassie Bennett, Malaroviyam Samikkannu, Farrah S. Mohammed, W. Dalton Dietrich, Suhrud M. Rajguru, Abhishek Prasad · 2018 · Biomaterials
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Bonney, Stephanie, Seitz, Scott, Ryan, Caitlin A., Jones, Kenneth L., Clarke, Penny, Tyler, Kenneth L., Siegenthaler, Julie A. · 2019 · mBio
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Simona Federica Spampinato, Valeria Bortolotto, Pier Luigi Canonico, Maria Angela Sortino, Mariagrazia Grilli · 2019 · Frontiers in Pharmacology
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Yasmin N. Ramadan, Saleh Fahad Alqifari, Khaled Alshehri, Amirah Alhowiti, Hyder Osman Mirghani, Tariq Alrasheed, Faisal Aljohani, Abdulaziz M Alghamdi, ‏Helal F. Hetta · 2025 · Molecular Neurobiology
Intrathecal somatic hypermutation of IgM in multiple sclerosis and neuroinflammation
Eduardo Beltrán, Birgit Obermeier, Markus Moser, Francisco Coret, María Simó, Isabel Boscá, Francisco Carlos Pérez Miralles, Luisa María Villar, Makbule Şenel, Hayrettin Tumani et al. · 2014 · Brain
Biomarkers in the diagnosis and study of psychogenic nonepileptic seizures: A systematic review
T. Sundararajan, G.E. Tesar, Xavier F. Jimenez · 2015 · Seizure
Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice
Bongnam Jung, Thomas D. Arnold, Elisabeth Raschperger, Konstantin Gaengel, Christer Betsholtz · 2017 · Journal of Cerebral Blood Flow & Metabolism
Diagnostic value of alternative techniques to gadolinium-based contrast agents in MR neuroimaging—a comprehensive overview
Anna Falk Delgado, Danielle van Westen, Markus Nilsson, Linda Knutsson, Pia C. Sundgren, Elna‐Marie Larsson, Alberto Falk Delgado · 2019 · Insights into Imaging
Risk factors for hemorrhage of brain arteriovenous malformation
Sonali S. Shaligram, Ethan A. Winkler, Daniel L. Cooke, Hua Su · 2019 · CNS Neuroscience & Therapeutics
Contribution of brain pericytes in blood–brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells
Marjolein Heymans, Ricardo Molina de Figueiredo, Lucie Dehouck, David Miguel Ferreira Francisco, Yasuteru Sano, Fumitaka Shimizu, Takashi Kanda, Rémy Bruggmann, Britta Engelhardt, Peter Winter et al. · 2020 · Fluids and Barriers of the CNS
Nanoparticle-Based Drug Delivery Systems: An Inspiring Therapeutic Strategy for Neurodegenerative Diseases
Linyan Duan, Xingfan Li, Rong Ji, Zhizhong Hao, Mingyue Kong, Xuejun Wen, Fangxia Guan, Shanshan Ma · 2023 · Polymers
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Arya Lekshmi Nair, Linda Groenendijk, Roos Overdevest, Tania M. Fowke, Rumaisha Annida, Orsola Mocellin, Helga E. de Vries, Nienke R. Wevers · 2023 · Frontiers in Molecular Neuroscience
Brain vascular heterogeneity: implications for disease pathogenesis and design of in vitro blood–brain barrier models
Midrelle E. Noumbissi, Bianca Galasso, Monique F. Stins · 2018 · Fluids and Barriers of the CNS