Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

Duman, Ronald S, Aghajanian, George K, Sanacora, Gerard, Krystal, John H·2016·Nature Medicine
DOI 10.1038/nm.4050

Cited by (136)

Items 101–136 of 136

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  5. Esketamine for treatment resistant depression
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  10. Ketamine specifically reduces cognitive symptoms in depressed patients: An investigation of associated neural activation patterns
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  12. Toward specific ways to combine ketamine and psychotherapy in treating depression
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  15. Esketamine combined with SSRI or SNRI for treatment-resistant depression
    Del Casale, Antonio, Spirito, Sara, Arena, Jan Francesco, Preissner, Saskia, Borro, Marina, Gentile, Giovanna, Modesti, Martina Nicole, Preissner, Robert, Ferracuti, Stefano, Simmaco, Maurizio · 2025 · JAMA Psychiatry
  16. All roads lead to glutamate: NMDA and AMPA receptors as targets for rapid-acting antidepressants
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  17. Longer-term open-label study of adjunctive riluzole in treatment-resistant depression
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  18. Analysis of antidepressant-like effects and action mechanisms of GSB-106, a small molecule, affecting the TrkB signaling
    Vakhitova, Yulia V., Kalinina, Tatiana S., Zainullina, Liana F., Lusta, Anastasiya Yu., Volkova, Anna V., Kudryashov, Nikita V., Gudasheva, Tatiana A., Shimshirt, Alexander A., Kadnikov, Ilya A., Voronin, Mikhail V. et al. · 2021 · International Journal of Molecular Sciences
  19. Iptakalim alleviates synaptic damages via targeting mitochondrial ATP‐sensitive potassium channel in depression
    Guo, Wei, Tang, Zi‐Yang, Cai, Zhen‐Yu, Zhao, Wen‐E, Yang, Jin, Wang, Xi‐Peng, Ji, Juan, Huang, Xin‐Xin, Sun, Xiu‐Lan · 2021 · The FASEB Journal
  20. Complicated Role of Exercise in Modulating Memory: A Discussion of the Mechanisms Involved
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  21. Profiling and Co-expression Network Analysis of Learned Helplessness Regulated mRNAs and lncRNAs in the Mouse Hippocampus
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  22. The Impact of BDNF, NTRK2, NGFR, CREB1, GSK3B, AKT, MAPK1, MTOR, PTEN, ARC, and SYN1 Genetic Polymorphisms in Antidepressant Treatment Response Phenotypes
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  23. Chronic Stress Induces Coordinated Cortical Microcircuit Cell–Type Transcriptomic Changes Consistent With Altered Information Processing
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  24. HCN channel inhibitor induces ketamine-like rapid and sustained antidepressant effects in chronic social defeat stress model
    Cai, Min, Zhu, Yingbo, Shanley, Mary Regis, Morel, Carole, Ku, Stacy M., Zhang, Hongxing, Shen, Yuan, Friedman, Allyson K., Han, Ming-Hu · 2023 · Neurobiology of Stress
  25. Beyond NMDA Receptors: A Narrative Review of Ketamine’s Rapid and Multifaceted Mechanisms in Depression Treatment
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  26. Therapeutic Antidepressant Potential of NONHSAG045500 in Regulating Serotonin Transporter in Major Depressive Disorder
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  27. Preliminary evidence for preserved synaptic density in late-life depression
    Vande Casteele, Thomas, Laroy, Maarten, Van Cauwenberge, Margot, Koole, Michel, Dupont, Patrick, Sunaert, Stefan, Van den Stock, Jan, Bouckaert, Filip, Van Laere, Koen, Emsell, Louise et al. · 2024 · Translational Psychiatry
  28. Challenges and rewards of in vivo synaptic density imaging, and its application to the study of depression
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  29. Neurological mechanism-based analysis of the role and characteristics of physical activity in the improvement of depressive symptoms
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  30. Advances in neurotransmitter-mediated prefrontal circuitry in depression
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  31. Glutamate receptor 4 as a fluid biomarker for the diagnosis of psychiatric disorders
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  32. Kappa Opioid Receptor Activation Induces Epigenetic Silencing of Brain-Derived Neurotropic Factor <i>via</i> HDAC5 in Depression
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  33. The metabotropic glutamate receptor 5 as a biomarker for psychiatric disorders
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  35. Multimodal synaptomics reveals coordinated synaptic activity, protein synthesis and reorganization in NMDAR regulation
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  36. Synaptic Plasticity—Intrinsic Excitability and Antidepressant Discovery
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