Misharin, Alexander V.

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

Yona, S., Kim, K.-W., Wolf, Y., Mildner, A., Varol, D., Breker, M., Strauss-Ayali, D., Viukov, S., Guilliams, M., Misharin, A., et al. (2013) · Immunity

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 3,245

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

Ziegler, C. G. K., Allon, S. J., Nyquist, S. K., Mbano, I. M., Miao, V. N., Tzouanas, C. N., Cao, Y., Yousif, A. S., Bals, J., Hauser, B. M., et al. (2020) · Cell

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 2,284

Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis

Reyfman, P. A., Walter, J. M., Joshi, N., Anekalla, K. R., McQuattie-Pimentel, A. C., Chiu, S., Fernandez, R., Akbarpour, M., Chen, C.-I., Ren, Z., et al. (2019) · American Journal of Respiratory and Critical Care Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisSingle-cell and spatial transcriptomics

Cited by 1,203

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

Misharin, A. V., Morales-Nebreda, L., Reyfman, P. A., Cuda, C. M., Walter, J. M., McQuattie-Pimentel, A. C., Chen, C.-I., Anekalla, K. R., Joshi, N., Williams, K. J. N., et al. (2017) · Journal of Experimental Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTransplantation: Methods and Outcomes

Cited by 1,133

The role of macrophages in the resolution of inflammation

Watanabe, S., Alexander, M., Misharin, A. V., & Budinger, G. R. S. (2019) · Journal of Clinical Investigation

Immune cells in cancerWound Healing and Treatments

Cited by 925

Flow Cytometric Analysis of Macrophages and Dendritic Cell Subsets in the Mouse Lung

Misharin, A. V., Morales-Nebreda, L., Mutlu, G. M., Budinger, G. R. S., & Perlman, H. (2013) · American Journal of Respiratory Cell and Molecular Biology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisImmune cells in cancer

Cited by 838

Mapping single-cell data to reference atlases by transfer learning

Lotfollahi, M., Naghipourfar, M., Luecken, M. D., Khajavi, M., Büttner, M., Wagenstetter, M., Avsec, Ž., Gayoso, A., Yosef, N., Interlandi, M., et al. (2022) · Nature Biotechnology

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 602

Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas

Piunti, A., Hashizume, R., Morgan, M. A., Bartom, E. T., Horbinski, C. M., Marshall, S. A., Rendleman, E. J., Ma, Q., Takahashi, Y.-H., Woodfin, A. R., et al. (2017) · Nature Medicine

Glioma Diagnosis and TreatmentChromatin Remodeling and Cancer

Cited by 445

Local and systemic responses to SARS-CoV-2 infection in children and adults

Yoshida, M., Worlock, K. B., Huang, N., Lindeboom, R. G. H., Butler, C. R., Kumasaka, N., Dominguez Conde, C., Mamanova, L., Bolt, L., Richardson, L., et al. (2022) · Nature

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 365

A novel Ly6C/Ly6G‐based strategy to analyze the mouse splenic myeloid compartment

Rose, S., Misharin, A., & Perlman, H. (2012) · Cytometry Part A

Immune cells in cancerInflammation biomarkers and pathways

Cited by 347

A spatially restricted fibrotic niche in pulmonary fibrosis is sustained by M-CSF/M-CSFR signalling in monocyte-derived alveolar macrophages

Joshi, N., Watanabe, S., Verma, R., Jablonski, R. P., Chen, C.-I., Cheresh, P., Markov, N. S., Reyfman, P. A., McQuattie-Pimentel, A. C., Sichizya, L., et al. (2020) · European Respiratory Journal

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisOccupational and environmental lung diseases

Cited by 344

Lung transplantation for patients with severe COVID-19

Bharat, A., Querrey, M., Markov, N. S., Kim, S., Kurihara, C., Garza-Castillon, R., Manerikar, A., Shilatifard, A., Tomic, R., Politanska, Y., et al. (2020) · Science Translational Medicine

Transplantation: Methods and OutcomesCOVID-19 Clinical Research Studies

Cited by 336

Alveolar Macrophages

Joshi, N., Walter, J. M., & Misharin, A. V. (2018) · Cellular Immunology

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 307

The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease

Schiller, H. B., Montoro, D. T., Simon, L. M., Rawlins, E. L., Meyer, K. B., Strunz, M., Vieira Braga, F. A., Timens, W., Koppelman, G. H., Budinger, G. R. S., et al. (2019) · American Journal of Respiratory Cell and Molecular Biology

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 245

The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging

McQuattie-Pimentel, A. C., Ren, Z., Joshi, N., Watanabe, S., Stoeger, T., Chi, M., Lu, Z., Sichizya, L., Aillon, R. P., Chen, C.-I., et al. (2021) · Journal of Clinical Investigation

Genetics, Aging, and Longevity in Model OrganismsImmune responses and vaccinations

Cited by 177

Flow Cytometry Reveals Similarities Between Lung Macrophages in Humans and Mice

Bharat, A., Bhorade, S. M., Morales-Nebreda, L., McQuattie-Pimentel, A. C., Soberanes, S., Ridge, K., DeCamp, M. M., Mestan, K. K., Perlman, H., Budinger, G. R. S., et al. (2016) · American Journal of Respiratory Cell and Molecular Biology

Immune cells in cancerTransplantation: Methods and Outcomes

Cited by 175

The heterogeneity of lung macrophages in the susceptibility to disease

Morales-Nebreda, L., Misharin, A. V., Perlman, H., & Budinger, G. R. S. (2015) · European Respiratory Review

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 162

Metformin targets mitochondrial electron transport to reduce air-pollution-induced thrombosis

Soberanes, S., Misharin, A. V., Jairaman, A., Morales-Nebreda, L., McQuattie-Pimentel, A. C., Cho, T., Hamanaka, R. B., Meliton, A. Y., Reyfman, P. A., Walter, J. M., et al. (2019) · Cell Metabolism

Air Quality and Health ImpactsMetabolism, Diabetes, and Cancer

Cited by 131

Biologically informed deep learning to query gene programs in single-cell atlases

Lotfollahi, M., Rybakov, S., Hrovatin, K., Hediyeh-zadeh, S., Talavera-López, C., Misharin, A. V., & Theis, F. J. (2023) · Nature Cell Biology

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 100

Biologically informed deep learning to infer gene program activity in single cells

Lotfollahi, M., Rybakov, S., Hrovatin, K., Hediyeh-zadeh, S., Talavera-López, C., Misharin, A. V., & Theis, F. J. (2022) · Nature Cell Biology

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 100

Eosinophil contamination of thioglycollate-elicited peritoneal macrophage cultures skews the functional readouts of in vitro assays

Misharin, A. V., Saber, R., & Perlman, H. (2012) · Journal of Leukocyte Biology

Immune Response and InflammationImmune cells in cancer

Cited by 38