The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic
Open accessAbstract
The global adoption of artemisinin-based combination therapies (ACTs) in the early 2000s heralded a new era in effectively treating drug-resistant Plasmodium falciparum malaria. However, several Southeast Asian countries have now reported the emergence of parasites that have decreased susceptibility to artemisinin (ART) derivatives and ACT partner drugs, resulting in increasing rates of treatment failures. Here we review recent advances in understanding how antimalarials act and how resistance develops, and discuss new strategies for effectively combatting resistance, optimizing treatment and advancing the global campaign to eliminate malaria.
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Cites
Artemisinin Resistance in Plasmodium falciparum Malaria
Dondorp, A. M., Nosten, F., Yi, P., Das, D., Phyo, A. P., Tarning, J., Lwin, K. M., Ariey, F., Hanpithakpong, W., Lee, S. J., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0808859 · Cited by 3,424
Spread of Artemisinin Resistance in Plasmodium falciparum Malaria
Ashley, E. A., Dhorda, M., Fairhurst, R. M., Amaratunga, C., Lim, P., Suon, S., Sreng, S., Anderson, J. M., Mao, S., Sam, B., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1314981 · Cited by 2,205
Brain Swelling and Death in Children with Cerebral Malaria
Seydel, K. B., Kampondeni, S. D., Valim, C., Potchen, M. J., Milner, D. A., Muwalo, F. W., Birbeck, G. L., Bradley, W. G., Fox, L. L., Glover, S. J., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1400116 · Cited by 404
Birth, D., Kao, W.-C., & Hunte, C. (2014) · Nature Communications · doi:10.1038/ncomms5029 · Cited by 205
The Peculiarities and Paradoxes of Plasmodium Heme Metabolism
Sigala, P. A., & Goldberg, D. E. (2014) · Annual Review of Microbiology · doi:10.1146/annurev-micro-091313-103537 · Cited by 129
Cited by
Uwimana, A., Legrand, E., Stokes, B. H., Ndikumana, J.-L. M., Warsame, M., Umulisa, N., Ngamije, D., Munyaneza, T., Mazarati, J.-B., Munguti, K., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-1005-2 · Cited by 831
Self-citationAshley, E. A., Pyae Phyo, A., & Woodrow, C. J. (2018) · The Lancet · doi:10.1016/s0140-6736(18)30324-6 · Cited by 553
Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria
Wicht, K. J., Mok, S., & Fidock, D. A. (2020) · Annual Review of Microbiology · doi:10.1146/annurev-micro-020518-115546 · Cited by 322
Self-citationLee, H. J., Georgiadou, A., Walther, M., Nwakanma, D., Stewart, L. B., Levin, M., Otto, T. D., Conway, D. J., Coin, L. J., & Cunnington, A. J. (2018) · Science Translational Medicine · doi:10.1126/scitranslmed.aar3619 · Cited by 141
Artemisia annua L. extracts inhibit the in vitro replication of SARS-CoV-2 and two of its variants
Nair, M. S., Huang, Y., Fidock, D. A., Polyak, S. J., Wagoner, J., Towler, M. J., & Weathers, P. J. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114016 · Cited by 122
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Metadata
- Authors
- Blasco, B., Leroy, D., & Fidock, D. A.
- Venue
- Nature Medicine
- Published
- 2017-08
- Volume
- 23
- Issue
- 8
- Pages
- 917-928
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W2742753960
- Cited by
- 576
- References
- 5
- FWCI
- 51.84
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
