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Saelens, J. W., Petersen, J. E. V., Freedman, E., Moseley, R. C., Konate, D. S., Diakité, S. A. S., Traoré, K., Vance, N., Fairhurst, R. M., Diakité, M., et al. (2021) · mSphere · doi:10.1128/msphere.00755-21 · Cited by 12 · see citing works

Malian children infected with Plasmodium ovale and Plasmodium falciparum display very similar gene expression profiles

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A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture

Andradi-Brown, C., Wichers-Misterek, J. S., von Thien, H., Höppner, Y. D., Scholz, J. A. M., Hansson, H. S., Hocke, E. F., Gilberger, T., Duffy, M. F., Lavstsen, T., et al. (2023) · eLife · doi:10.7554/elife.87726 · Cited by 11 · see citing works

Gene expression analyses reveal differences in children’s response to malaria according to their age

Tebben, K., Yirampo, S., Coulibaly, D. M., Kone, A. K., Laurens, M. B., Stucke, E. M., Dembélé, A., Tolo, Y., Traoré, K., Niangaly, A., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-46416-3 · Cited by 10 · see citing works

Exploiting integrative metabolomics to study host–parasite interactions in Plasmodium infections

Nikulkova, M., Abdrabou, W. S., Carlton, J. M., & Idaghdour, Y. (2024) · Trends in Parasitology · doi:10.1016/j.pt.2024.02.007 · Cited by 10 · see citing works

Asymptomatic Plasmodium falciparum infection evades triggering a host transcriptomic response

Prah, D. A., Dunican, C., Amoah, L. E., Marjaneh, M. M., Kaforou, M., Nordgren, A., Jones‐Warner, W., Aniweh, Y., Awandare, G. A., Cunnington, A. J., et al. (2023) · Journal of Infection · doi:10.1016/j.jinf.2023.06.013 · Cited by 10 · see citing works

Host and Parasite Transcriptomic Changes upon Successive Plasmodium falciparum Infections in Early Childhood

Bradwell, K. R., Coulibaly, D. M., Kone, A. K., Laurens, M. B., Dembélé, A., Tolo, Y., Traoré, K., Niangaly, A., Berry, A. A., Kouriba, B., et al. (2020) · mSystems · doi:10.1128/msystems.00116-20 · Cited by 10 · see citing works

Dual RNA Sequencing Meta-analysis in Plasmodium Infection Identifies Host-Parasite Interactions

Mukherjee, P., Burgio, G., & Heitlinger, E. G. (2021) · mSystems · doi:10.1128/msystems.00182-21 · Cited by 9 · see citing works

OLFM4 regulates the antimicrobial and DNA binding activity of neutrophil cationic proteins

Vandenberghe-Dürr, S., Gilliet, M. F., & Domizio, J. D. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114863 · Cited by 9 · see citing works

Iron transport pathways in the human malaria parasite Plasmodium falciparum revealed by RNA-sequencing

Wunderlich, J., Kotov, V., Votborg-Novél, L., Ntalla, C., Geffken, M., Peine, S., Portugal, S., & Strauss, J. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1480076 · Cited by 10 · see citing works

A shared inflammatory signature across severe malaria syndromes manifested by transcriptomic, proteomic and metabolomic analyses

Sobota, R. S., Stucke, E. M., Coulibaly, D. M., Lawton, J. G., Cummings, B. E., Sebastian, S., Dara, A., Munro, J. B., Ouattara, A., Kone, A. K., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-59281-5 · Cited by 9 · see citing works

Analysis of blood and nasal epithelial transcriptomes to identify mechanisms associated with control of SARS-CoV-2 viral load in the upper respiratory tract

Marjaneh, M. M., Challenger, J. D., Salas, A., Gómez‐Carballa, A., Sivananthan, A., Calle, I. R., Barbeito‐Castiñeiras, G., Foo, C. Y., Wu, Y., Liew, F., et al. (2023) · Journal of Infection · doi:10.1016/j.jinf.2023.10.009 · Cited by 9 · see citing works

Comparison of whole blood and spleen transcriptional signatures over the course of an experimental malaria infection

Talavera-López, C. N., Bediako, Y., Lin, J., Valletta, J. J., Recker, M., & Langhorne, J. (2019) · Scientific Reports · doi:10.1038/s41598-019-52388-y · Cited by 9 · see citing works

Metagenomic next-generation sequencing in osteoarticular infections with a focus on pediatrics: current concepts and clinical applications

Gupton, M., & Burns, J. D. (2023) · EFORT Open Reviews · doi:10.1530/eor-22-0136 · Cited by 9 · see citing works

Decrypting the complexity of the human malaria parasite biology through systems biology approaches

Chahine, Z. M., & Roch, K. G. L. (2022) · Frontiers in Systems Biology · doi:10.3389/fsysb.2022.940321 · Cited by 8 · see citing works

Three Signatures of Adaptive Polymorphism Exemplified by Malaria-Associated Genes

Tennessen, J. A., & Duraisingh, M. T. (2020) · Molecular Biology and Evolution · doi:10.1093/molbev/msaa294 · Cited by 7 · see citing works

Molecular basis of synchronous replication of malaria parasites in the blood stage

dos Santos, B. M., Pereira, P. H. S., & Garcia, C. R. S. (2021) · Current Opinion in Microbiology · doi:10.1016/j.mib.2021.08.002 · Cited by 6 · see citing works

SHIP1 modulates antimalarial immunity by bridging the crosstalk between type I IFN signaling and autophagy

Li, H., Yang, S., Zeng, K., Guo, J., Wu, J., Jiang, H., Xie, Y., Hu, Z., Lu, J., Yang, J., et al. (2023) · mBio · doi:10.1128/mbio.03512-22 · Cited by 6 · see citing works

Single-cell profiling reveals immunoregulation of artemisinin on CD8+GZMB+ T cells via JAK2-STAT3 in malaria-infected mice

Chen, J., Gao, P., He, X., Hu, Y., Zhou, W., Liu, Y., Wang, J., Liu, X., Bai, Y., Chen, L., et al. (2025) · The Innovation · doi:10.1016/j.xinn.2025.101080 · Cited by 5 · see citing works

Uncovering complex molecular networks in host–pathogen interactions using systems biology

Peters, J. M., Solomon, S. L., Itoh, C. Y., & Bryson, B. D. (2019) · Emerging Topics in Life Sciences · doi:10.1042/etls20180174 · Cited by 5 · see citing works

Adjunctive ruxolitinib attenuates inflammation and enhances antiparasitic immunity in human volunteers experimentally infected with Plasmodium falciparumPreprint

Webster, R. A., Oyong, D. A., Rahman, A. N. A., Potter, A. J., Mukhiya, R., Sahai, N., Leelasena, I., Ujvary, E., Mathison, S., Andrew, D. W., et al. (2025) · medRxiv · doi:10.1101/2025.03.26.25324737 · Cited by 5 · see citing works

Protective effects of artesunate on the neurovascular unit by regulating PDGFRβ signaling in experimental cerebral malaria

Dai, Y., Zheng, Z., Ma, J., Liu, C., Deng, S., Liang, Y., Liu, T., Wang, L., Li, Y., & Chen, L. (2025) · Biochemical Pharmacology · doi:10.1016/j.bcp.2025.117023 · Cited by 4 · see citing works

Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites

Lansink, L. I. M., Skinner, O. P., Engel, J. A., Lee, H. J., Soon, M. S. F., Williams, C. G., SheelaNair, A., Pernold, C. P. S., Laohamonthonkul, P., Akter, J., et al. (2023) · mBio · doi:10.1128/mbio.01129-23 · Cited by 4 · see citing works

Host Transcriptional Meta-signatures Reveal Diagnostic Biomarkers for Plasmodium falciparum Malaria

Silva, N. I., Souza, P. F. L., da Silva, B. F., Fonseca, S. G., & Gardinassi, L. G. (2024) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiae041 · Cited by 4 · see citing works

Structural and Evolutionary Relationships of Melanin Cascade Proteins in Cnidarian Innate Immunity

Buren, E. W. V., Ponce, I. E., Beavers, K. M., Stokes, A., Cornelio, M. N., Emery, M. A., & Mydlarz, L. D. (2024) · Integrative and Comparative Biology · doi:10.1093/icb/icae115 · Cited by 4 · see citing works

Transcriptomic analyses of differentially expressed human genes, micro RNAs and long-non-coding RNAs in severe, symptomatic and asymptomatic malaria infection

Oboh, M. A., Morenikeji, O. B., Ojurongbe, O. D., & Thomas, B. N. (2024) · Scientific Reports · doi:10.1038/s41598-024-67663-w · Cited by 4 · see citing works

Expression of CD11a, CD11b, CD11c, and CD18 on Neutrophils from Different Clinical Types of Malaria in Malawian Children

Mandala, W. L. (2022) · Journal of Blood Medicine · doi:10.2147/jbm.s343109 · Cited by 4 · see citing works

Machine learning-based identification of a transcriptomic blood signature discriminating between systemic autoimmunity and infection

Verrou, K., Vlachogiannis, N. I., Theofilopoulos, A. N., Tektonidou, M. G., Κόλλιας, Γ., Nikolaou, C., & Sfikakis, P. P. (2025) · Med · doi:10.1016/j.medj.2025.100840 · Cited by 3 · see citing works

Primary infection enhances neutrophil-mediated host defense by educating HSPCs

Wu, P. S., Zhang, Q., Xu, X., He, S., Liu, Z., Li, Y., & Guo, R. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112382 · Cited by 3 · see citing works

Highly Variable Expression of Merozoite Surface Protein MSPDBL2 in Diverse Plasmodium falciparum Clinical Isolates and Transcriptome Scans for Correlating Genes

Hocking, S. E., Stewart, L. B., Fréville, A., Reid, A. J., Tarr, S. J., Tetteh, K. K. A., Flueck, C., Ahouidi, A. D., Amambua‐Ngwa, A., Diakité, M., et al. (2022) · mBio · doi:10.1128/mbio.01948-22 · Cited by 3 · see citing works

Multicohort transcriptome analysis of whole blood identifies robust human response signatures in Plasmodium falciparum infections

Zhang, Y., Su, X., Li, J., Shi, J., & Xie, L. (2022) · Malaria Journal · doi:10.1186/s12936-022-04374-5 · Cited by 3 · see citing works

Neutrophil activation, acute lung injury and disease severity in Plasmodium knowlesi malaria

Tan, A. F., Sakam, S. S. B., Piera, K. A., Rajahram, G. S., William, T., Barber, B. E., Anstey, N. M., Grigg, M. J., & Kho, S. (2024) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0012424 · Cited by 3 · see citing works

Transcriptomic profiles of Plasmodium falciparum and Plasmodium vivax -infected individuals in IndonesiaPreprint

Bobowik, K., Syafruddin, D., Darusallam, C. C., Sudoyo, H., Wells, C. A., & Romero, I. G. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.01.07.425684 · Cited by 3 · see citing works

Mitochondrial activity promotes neutrophil degranulation and endothelial dysfunction in systemic infections

Zakrzewski, P., Rice, C. M., Naveh, C. A., Dowell, I., Fleming, K., Ramesh, A. V., Jones, R. L., Moura, P. L., Cela, D., Groves, S., et al. (2026) · EMBO Molecular Medicine · doi:10.1038/s44321-026-00453-1 · Cited by 2 · see citing works

Prolonged dysregulation of gene expression and biomarkers of coagulation, fibrinolysis, and endothelium in pediatric central nervous system malaria

Dent, A. E., Rosa, B. A., Dobbs, K. R., Ogolla, S., Midem, D., Embury, P., Skomorovska-Prokvolit, Y., Hannon, E. R., Koech, E., Schmaier, A. H., et al. (2025) · BMC Infectious Diseases · doi:10.1186/s12879-025-11957-5 · Cited by 2 · see citing works

Methylene blue treatment of fatal cerebral malaria and identification of potential blood biomarkers

Hang, J. W., Leong, Y. W., Narang, V., Sunyakumthorn, P., Im‐Erbsin, R., Foo, S., Lum, J., Lee, B. T. K., Brown, A. E., Rénia, L., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-65552-y · Cited by 2 · see citing works

The malarial blood transcriptome: translational applications

Dunican, C., Andradi-Brown, C., Ebmeier, S., Georgiadou, A., & Cunnington, A. J. (2024) · Biochemical Society Transactions · doi:10.1042/bst20230497 · Cited by 2 · see citing works

Elevated Inflammation Associated with Markers of Neutrophil Function and Gastrointestinal Disruption in Pilot Study of Plasmodium fragile Co-Infection of ART-Treated SIVmac239+ Rhesus Macaques

Nemphos, S. M., Green, H. C., Prusak, J. E., Fell, S. L., Goff, K. A., Varnado, M., Didier, K., Guy, N., Moström, M. J., Tatum, C., et al. (2024) · Viruses · doi:10.3390/v16071036 · Cited by 2 · see citing works

JAK/STAT inhibition protects glucocorticoid receptor knockout mice from lethal malaria-induced hypoglycemia and hyperinflammation

Prenen, F., Vandermosten, L., Knoops, S., Pollenus, E., Possemiers, H., de Richecour, P. D., Caratti, G., Cawthorne, C., Vettorazzi, S., Cranshoff, Y., et al. (2025) · EMBO Molecular Medicine · doi:10.1038/s44321-025-00264-w · Cited by 2 · see citing works

Human transcriptional signature of protection after Plasmodium falciparum immunization and infectious challenge via mosquito bites

Mura, M., Misganaw, B., Gautam, A., Robinson, T. M., Chaudhury, S., Bansal, N., Martins, A. J., Tsang, J. S., Hammamieh, R., & Bergmann‐Leitner, E. S. (2023) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2023.2282693 · Cited by 2 · see citing works

CD209 and Not CD28 or STAT6 Polymorphism Mediates Clinical Malaria and Parasitemia among Children from Nigeria

Morenikeji, O., Metelski, J. L., Hawkes, M. E., Capria, A., Seamans, B. N., Falade, C., Ojurongbe, O., & Thomas, B. (2020) · Microorganisms · doi:10.3390/microorganisms8020158 · Cited by 2 · see citing works

Immunogenetic response to a malaria-like parasite in a wild primatePreprint

Trujillo, A. E., & Bergey, C. M. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.24.396317 · Cited by 2 · see citing works

Distinct Plasmodium falciparum Erythrocyte Membrane Protein 1 Domain Cassette-Associated Antibody Gaps Specific to Cerebral Malaria and Severe Malarial Anemia

Travassos, M. A., Han, P., Coulibaly, D., Stucke, E. M., Zhou, A. E., Shrestha, B., Nakajima, R., Jain, A., Taghavian, O., Jasinskas, A., et al. (2026) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiag256 · Cited by 1 · see citing works

Multicohort analysis identifies conserved transcriptional interactions between humans and Plasmodium falciparum

da Silva, B. F., Silva, N. I., Souza, P. F. L., Guimarães, T. P., & Gardinassi, L. G. (2024) · ImmunoInformatics · doi:10.1016/j.immuno.2024.100044 · Cited by 1 · see citing works

Reply to Liu et al

Nallandhighal, S., & Tran, T. M. (2019) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiz121 · Cited by 1 · see citing works

Identifying host-pathogen interactions which cause severe malaria

Georgiadou, A. (2019) · Spiral (Imperial College London) · doi:10.25560/82355

Interactive transcriptome analysis of malaria patients and infectingPlasmodium falciparumPreprint

Yamagishi, J., Natori, A., Tolba, M. E. M., Mongan, A. E., Sugimoto, C., Katayama, T., Kawashima, S., Makałowski, W., Maeda, R., Eshita, Y., et al. (2014) · Genome Research · doi:10.1101/gr.158980.113 · Cited by 82 · see citing works

Host and Parasite Transcriptomic Changes upon Successive Plasmodium falciparum Infections in Early Childhood

Bradwell, K. R., Coulibaly, D. M., Kone, A. K., Laurens, M. B., Dembélé, A., Tolo, Y., Traoré, K., Niangaly, A., Berry, A. A., Kouriba, B., et al. (2020) · mSystems · doi:10.1128/msystems.00116-20 · Cited by 10 · see citing works

Reply to: Relationship of circulating Plasmodium falciparum lifecycle stage to circulating parasitemia and total parasite biomass

Thomson-Luque, R., Votborg-Novél, L., Osório, N. S., & Portugal, S. (2022) · Nature Communications · doi:10.1038/s41467-022-32998-3

Plasmodium falciparum gene expression signatures and antibody profiling implicate the fikk, phist, and surf multigene families in severe malaria syndromes

Cummings, B. E., Stucke, E. M., Coulibaly, D. M., Lawton, J. G., Sobota, R. S., Kone, A. K., Kané, B., Guindo, B., Tangara, B., Sissoko, M., et al. (2025) · Journal of Infection · doi:10.1016/j.jinf.2025.106655 · Cited by 2 · see citing works