HIV-1 Nef associated PAK and PI3-Kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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Importance of the nef gene for maintenance of high virus loads and for development of AIDS

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Direct Regulation of the Akt Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate

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Absence of Intact nef Sequences in a Long-Term Survivor with Nonprogressive HIV-1 Infection

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Membrane and Morphological Changes in Apoptotic Cells Regulated by Caspase-Mediated Activation of PAK2

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Regulation of apoptosis by viral gene products

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Polyoma virus transforming protein associates with the product of the c-src cellular gene

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Nef Harbors a Major Determinant of Pathogenicity for an AIDS-like Disease Induced by HIV-1 in Transgenic Mice

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p21-Activated Kinase 1 (Pak1) Regulates Cell Motility in Mammalian Fibroblasts

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Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene

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p21-Activated Kinase 1 Phosphorylates the Death Agonist Bad and Protects Cells from Apoptosis

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HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell

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Mechanisms of HIV-associated lymphocyte apoptosis

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HIV-1 nef leads to inhibition or activation of T cells depending on its intracellular localization

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The Nef protein of HIV-1 associates with rafts and primes T cells for activation

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p21-Activated protein kinase: a crucial component of morphological signaling?

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Induction of Fas Ligand Expression by HIV Involves the Interaction of Nef with the T Cell Receptor ζ Chain

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Interactions between HIV1 Nef and Vacuolar ATPase Facilitate the Internalization of CD4

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Activation of Vav by Nef Induces Cytoskeletal Rearrangements and Downstream Effector Functions

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The N-Terminus of Nef from HIV-1/SIV Associates with a Protein Complex Containing Lck and a Serine Kinase

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Interactions of HIV-1 NEF with cellular signal transducing proteins

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The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor beta receptor.

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CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1

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Bad Can Act as a Key Regulator of T Cell Apoptosis and T Cell Development

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p21-Activated Kinase 1 Plays a Critical Role in Cellular Activation by Nef

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Cutting Edge: p21-Activated Kinase (PAK) Is Required for Fas-Induced JNK Activation in Jurkat Cells

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Cytokine-Induced Protein Kinase B Activation and Bad Phosphorylation Do Not Correlate with Cell Survival of Hemopoietic Cells

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Anti-apoptotic strategies of lymphotropic viruses

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Lentivirus Nef Specifically Activates Pak2

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Regulation of Protein Kinase B in Rat Adipocytes by Insulin, Vanadate, and Peroxovanadate

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Evidence of a Role for Phosphatidylinositol 3-Kinase Activation in the Blocking of Apoptosis by Polyomavirus Middle T Antigen

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Protein kinase B/Akt is activated by polyomavirus middle-T antigen via a phosphatidylinositol 3-kinase-dependent mechanism

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HIV-1 Nef Plays an Essential Role in Two Independent Processes in CD4 Down-regulation: Dissociation of the CD4–p56 Complex and Targeting of CD4 to Lysosomes

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HIV Nef is Secreted in Exosomes and Triggers Apoptosis in Bystander CD4+ T Cells

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To kill or be killed: viral evasion of apoptosis

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Getting the “Kill” into “Shock and Kill”: Strategies to Eliminate Latent HIV

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Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy

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Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL

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