The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Calmodulin kinase II inhibition protects against structural heart disease
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1 retracted
Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels
Dzhura, I., Wu, Y., Colbran, R. J., Balser, J. R., & Anderson, M. E. (2000) · Nature Cell Biology · doi:10.1038/35004052 · Cited by 335
Self-citationRetractedCardiac excitation–contraction coupling
Bers, D. M. (2002) · Nature · doi:10.1038/415198a · Cited by 4,744
Protein kinases — the major drug targets of the twenty-first century?
Cohen, P. (2002) · Nature Reviews Drug Discovery · doi:10.1038/nrd773 · Cited by 2,186
PKA Phosphorylation Dissociates FKBP12.6 from the Calcium Release Channel (Ryanodine Receptor)
Marx, S. O., Reiken, S., Hisamatsu, Y., Jayaraman, T., Burkhoff, D., Rosemblit, N., & Marks, A. R. (2000) · Cell · doi:10.1016/s0092-8674(00)80847-8 · Cited by 1,978
Calcium Sparks: Elementary Events Underlying Excitation-Contraction Coupling in Heart Muscle
Cheng, H., Lederer, W. J., & Cannell, M. B. (1993) · Science · doi:10.1126/science.8235594 · Cited by 1,935
Self-citationPan, L., Gurevich, E. V., & Gurevich, V. V. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209532200 · Cited by 1,759
Self-citationJessup, M., & Brozena, S. (2003) · New England Journal of Medicine · doi:10.1056/nejmra021498 · Cited by 1,564
Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure.
Gwathmey, J. K., Copelas, L., MacKinnon, R., Schoen, F. J., Feldman, M. D., Grossman, W., & Morgan, J. P. (1987) · Circulation Research · doi:10.1161/01.res.61.1.70 · Cited by 924
Defective Excitation-Contraction Coupling in Experimental Cardiac Hypertrophy and Heart Failure
Gómez, A. M., Valdivia, H. H., Cheng, H., Lederer, M. R., Santana, L. F., Cannell, M. B., McCune, S. A., Altschuld, R. A., & Lederer, W. J. (1997) · Science · doi:10.1126/science.276.5313.800 · Cited by 758
Self-citationFabiato, A., & Fabiato, F. (1975) · The Journal of Physiology · doi:10.1113/jphysiol.1975.sp011026 · Cited by 683
Wehrens, X. H. T., Lehnart, S. E., Reiken, S. R., & Marks, A. R. (2004) · Circulation Research · doi:10.1161/01.res.0000125626.33738.e2 · Cited by 623
Structure–function of the multifunctional Ca2+/calmodulin-dependent protein kinase II
HUDMON, A., & SCHULMAN, H. (2002) · Biochemical Journal · doi:10.1042/bj20020228 · Cited by 615
Zhang, T., Maier, L. S., Dalton, N. D., Miyamoto, S., Ross, J., Bers, D. M., & Brown, J. H. (2003) · Circulation Research · doi:10.1161/01.res.0000069686.31472.c5 · Cited by 556
Gao, T., Yatani, A., Dell'Acqua, M. L., Sako, H., Green, S. A., Dascal, N., Scott, J. D., & Hosey, M. M. (1997) · Neuron · doi:10.1016/s0896-6273(00)80358-x · Cited by 519
Maier, L. S., Zhang, T., Chen, L., DeSantiago, J., Brown, J. H., & Bers, D. M. (2003) · Circulation Research · doi:10.1161/01.res.0000069685.20258.f1 · Cited by 433
Zhu, W.-Z., Wang, S.-Q., Chakir, K., Yang, D., Zhang, T., Brown, J. H., Devic, E., Kobilka, B. K., Cheng, H., & Xiao, R.-P. (2003) · Journal of Clinical Investigation · doi:10.1172/jci16326 · Cited by 424
Doughty, R. N., Whalley, G. A., Gamble, G., MacMahon, S., & Sharpe, N. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(97)00012-0 · Cited by 422
Benedict, C. R., Shelton, B., Johnstone, D. E., Francis, G., Greenberg, B., Konstam, M., Probstfield, J. L., & Yusuf, S. (1996) · Circulation · doi:10.1161/01.cir.94.4.690 · Cited by 353
Activation of calmodulin by various metal cations as a function of ionic radius.
Chao, S. H., Suzuki, Y., Zysk, J. R., & Cheung, W. Y. (1984) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)14991-2 · Cited by 343
Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis.
Benjamin, I. J., Jalil, J. E., Tan, L. B., Cho, K., Weber, K. T., & Clark, W. A. (1989) · Circulation Research · doi:10.1161/01.res.65.3.657 · Cited by 343
Hoch, B., Meyer, R., Hetzer, R., Krause, E.-G., & Karczewski, P. (1999) · Circulation Research · doi:10.1161/01.res.84.6.713 · Cited by 328
Yue, D. T., Herzig, S., & Marban, E. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.2.753 · Cited by 309
Transgenic expression of green fluorescence protein can cause dilated cardiomyopathy
Huang, W.-Y., Aramburu, J., Douglas, P. S., & Izumo, S. (2000) · Nature Medicine · doi:10.1038/74914 · Cited by 271
Calmodulin Kinase II and Arrhythmias in a Mouse Model of Cardiac Hypertrophy
Wu, Y., Temple, J., Zhang, R., Dzhura, I., Zhang, W., Trimble, R., Roden, D. M., Passier, R., Olson, E. N., Colbran, R. J., et al. (2002) · Circulation · doi:10.1161/01.cir.0000027583.73268.e7 · Cited by 268
Self-citationEMOTIONAL STIMULATION OF ADRENAL SECRETION
Cannon, W. B., & de la Paz, D. (1911) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1911.28.1.64 · Cited by 241
Ca-dependent facilitation of cardiac Ca current is due to Ca-calmodulin-dependent protein kinase
Yuan, W., & Bers, D. M. (1994) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1994.267.3.h982 · Cited by 237
Anderson, M. E., Braun, A. P., Schulman, H., & Premack, B. A. (1994) · Circulation Research · doi:10.1161/01.res.75.5.854 · Cited by 227
Self-citationRamirez, M. T., Zhao, X.-L., Schulman, H., & Brown, J. H. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.49.31203 · Cited by 210
Xiao, R. P., Cheng, H., Lederer, W. J., Suzuki, T., & Lakatta, E. G. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.20.9659 · Cited by 191
Self-citationRodriguez, P., Bhogal, M., & Colyer, J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.c301180200 · Cited by 189
Alseikhan, B. A., DeMaria, C. D., Colecraft, H. M., & Yue, D. T. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.262372999 · Cited by 186
Sinoatrial Node Pacemaker Activity Requires Ca2+/Calmodulin-Dependent Protein Kinase II Activation
Vinogradova, T. M., Zhou, Y.-Y., Bogdanov, K. Y., Yang, D., Kuschel, M., Cheng, H., & Xiao, R.-P. (2000) · Circulation Research · doi:10.1161/01.res.87.9.760 · Cited by 185
Aldosterone Upregulates Ca2+Current in Adult Rat Cardiomyocytes
Bénitah, J.-P., & Vassort, G. (1999) · Circulation Research · doi:10.1161/01.res.85.12.1139 · Cited by 162
Chu, G., Lester, J. W., Young, K. B., Luo, W., Zhai, J., & Kranias, E. G. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004079200 · Cited by 160
Hagemann, D., Kuschel, M., Kuramochi, T., Zhu, W., Cheng, H., & Xiao, R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.c000253200 · Cited by 147
Kinase- and phosphatase-anchoring proteins: harnessing the dynamic duo
Bauman, A. L., & Scott, J. D. (2002) · Nature Cell Biology · doi:10.1038/ncb0802-e203 · Cited by 132
Currie, S., Loughrey, C. M., Craig, M. A., & Smith, G. L. (2004) · Biochemical Journal · doi:10.1042/bj20031043 · Cited by 132
Effects of Chronicβ-Adrenergic Receptor Stimulation in Mice
Kudej, R. K., Iwase, M., Uechi, M., Vatner, D. E., Oka, N., Ishikawa, Y., Shannon, R. P., Bishop, S. P., & Vatner, S. F. (1997) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.1997.0508 · Cited by 117
Drago, G. A., & Colyer, J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)31500-4 · Cited by 99
Rottman, J. N., Ni, G., Khoo, M., Wang, Z., Zhang, W., Anderson, M. E., & Madu, E. C. (2003) · Journal of the American Society of Echocardiography · doi:10.1067/s0894-7317(03)00471-1 · Cited by 90
Self-citationCalmodulin kinase is a molecular switch for cardiac excitation –contraction coupling
Wu, Y., Colbran, R. J., & Anderson, M. E. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.051449198 · Cited by 89
Self-citationBraun, A. P., & Schulman, H. (1995) · The Journal of Physiology · doi:10.1113/jphysiol.1995.sp020944 · Cited by 89
Ichihara, S., Senbonmatsu, T., Price, E., Ichiki, T., Gaffney, F. A., & Inagami, T. (2002) · Circulation · doi:10.1161/01.cir.0000033826.52681.37 · Cited by 89
Self-citationSah, R., Ramírez, R. J., Kaprielian, R., & Backx, P. H. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.0201b.x · Cited by 80
Distinct Roles for the Helicases of TFIIH in Transcript Initiation and Promoter Escape
Bradsher, J., Coin, F., & Egly, J. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.4.2532 · Cited by 72
Patberg, K. W., Plotnikov, A. N., Quamina, A., Gainullin, R. Z., Rybin, A., Danilo, P., Sun, L. S., & Rosen, M. R. (2003) · Circulation Research · doi:10.1161/01.res.0000088785.24381.2f · Cited by 59
Cited by
A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation
Erickson, J. R., Joiner, M.-L. A., Guan, X., Kutschke, W., Yang, J., Oddis, C. V., Bartlett, R. K., Lowe, J. S., O'Donnell, S. E., Aykin-Burns, N., et al. (2008) · Cell · doi:10.1016/j.cell.2008.02.048 · Cited by 1,122
Self-citationBernardo, B. C., Weeks, K. L., Pretorius, L., & McMullen, J. R. (2010) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2010.04.005 · Cited by 894
CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress–induced myocardial necroptosis
Zhang, T., Zhang, Y., Cui, M., Jin, L., Wang, Y., Lv, F., Liu, Y., Zheng, W., Shang, H., Zhang, J., et al. (2016) · Nature Medicine · doi:10.1038/nm.4017 · Cited by 790
Brundel, B. J. J. M., Ai, X., Hills, M. T., Kuipers, M. F., Lip, G. Y. H., & de Groot, N. M. S. (2022) · Nature Reviews Disease Primers · doi:10.1038/s41572-022-00347-9 · Cited by 499
Signaling effectors underlying pathologic growth and remodeling of the heart
van Berlo, J. H., Maillet, M., & Molkentin, J. D. (2013) · Journal of Clinical Investigation · doi:10.1172/jci62839 · Cited by 445
Metadata
- Authors
- Zhang, R., Khoo, M. S. C., Wu, Y., Yang, Y., Grueter, C. E., Ni, G., Price, E. E., Thiel, W., Guatimosim, S., Song, L.-S., Madu, E. C., Shah, A. N., Vishnivetskaya, T. A., Atkinson, J. B., Gurevich, V. V., Salama, G., Lederer, W. J., Colbran, R. J., & Anderson, M. E.
- Venue
- Nature Medicine
- Published
- 2005-03-27
- Volume
- 11
- Issue
- 4
- Pages
- 409-417
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W2001261561
- Cited by
- 579
- References
- 47
- FWCI
- 24.61
- Type
- journal article
- Language
- en
- Open access
- closed
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.