The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
PI3Kγ inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Central Role for G Protein-Coupled Phosphoinositide 3-Kinase γ in Inflammation
Hirsch, E., Katanaev, V. L., Garlanda, C., Azzolino, O., Pirola, L., Silengo, L., Sozzani, S., Mantovani, A., Altruda, F., & Wymann, M. P. (2000) · Science · doi:10.1126/science.287.5455.1049 · Cited by 1,209
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
Sasaki, T., Irie-Sasaki, J., Jones, R. G., Oliveira-dos-Santos, A. J., Stanford, W. L., Bolon, B., Wakeham, A., Itie, A., Bouchard, D., Kozieradzki, I., et al. (2000) · Science · doi:10.1126/science.287.5455.1040 · Cited by 1,031
Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis
Camps, M., Rückle, T., Ji, H., Ardissone, V., Rintelen, F., Shaw, J., Ferrandi, C., Chabert, C., Gillieron, C., Françon, B., et al. (2005) · Nature Medicine · doi:10.1038/nm1284 · Cited by 750
Self-citationSignalling by PI3K isoforms: insights from gene-targeted mice
Vanhaesebroeck, B., Ali, K., Bilancio, A., Geering, B., & Foukas, L. C. (2005) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2005.02.008 · Cited by 444
Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice.
Jevnikar, A. M., Grusby, M. J., & Glimcher, L. H. (1994) · The Journal of experimental medicine · doi:10.1084/jem.179.4.1137 · Cited by 188
R.‐Borlado, L., Redondo, C., Alvarez, B., Jimenez, C., Criado, L. M., Flores, J., Marcos, M. A. R., Martinez‐A., C., Balomenos, D., & Carrera, A. C. (2000) · The FASEB Journal · doi:10.1096/fasebj.14.7.895 · Cited by 175
Self-citationTreatment of lupus with corticosteroids
Chatham, W. W., & Kimberly, R. P. (2001) · Lupus · doi:10.1191/096120301675075008 · Cited by 157
Apoptosis, fas and systemic autoimmunity: the MRL-Ipr/Ipr model
Singer, G. G., Carrera, A. C., Marshak‐Rothstein, A., Martínez‐A, C., & Abbas, A. K. (1994) · Current Opinion in Immunology · doi:10.1016/0952-7915(94)90013-2 · Cited by 152
Self-citationGenetic dissection of systemic lupus erythematosus
Wakeland, E. K., Wandstrat, A. E., Liu, K., & Morel, L. M. (1999) · Current Opinion in Immunology · doi:10.1016/s0952-7915(99)00039-4 · Cited by 152
Increased Severity of Murine Lupus in Female Mice Is Due to Enhanced Expansion of Pathogenic T Cells
Lang, T. J., Nguyen, P., Papadimitriou, J. C., & Via, C. S. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.11.5795 · Cited by 40
Cited by
Phosphoinositides: Tiny Lipids With Giant Impact on Cell Regulation
Balla, T. (2013) · Physiological Reviews · doi:10.1152/physrev.00028.2012 · Cited by 1,638
PI3K signalling in inflammation
Hawkins, P. T., & Stephens, L. R. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2014.12.006 · Cited by 541
Insulin resistance and atherosclerosis
Semenkovich, C. F. (2006) · Journal of Clinical Investigation · doi:10.1172/jci29024 · Cited by 481
PI3Kδ and PI3Kγ: partners in crime in inflammation in rheumatoid arthritis and beyond?
Rommel, C., Camps, M., & Ji, H. (2007) · Nature Reviews Immunology · doi:10.1038/nri2036 · Cited by 398
Self-citationThe PI3K/Akt/mTOR pathway in innate immune cells: emerging therapeutic applications
Weichhart, T., & Säemann, M. D. (2008) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2008.098459 · Cited by 323
B cells as therapeutic targets in SLE
Sanz, I., & Lee, F. E.-H. (2010) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2010.68 · Cited by 261
Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRs
Rathinaswamy, M. K., Jenkins, M. L., Duewell, B. R., Zhang, X., Harris, N. J., Evans, J. T., Stariha, J. T. B., Dalwadi, U., Fleming, K. D., Ranga-Prasad, H., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112172 · Cited by 28
Metadata
- Authors
- Barber, D. F., Bartolomé, A., Hernandez, C., Flores, J. M., Redondo, C., Fernandez-Arias, C., Camps, M., Rückle, T., Schwarz, M. K., Rodríguez, S., Martinez-A, C., Balomenos, D., Rommel, C., & Carrera, A. C.
- Venue
- Nature Medicine
- Published
- 2005-08-28
- Volume
- 11
- Issue
- 9
- Pages
- 933-935
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W1987218173
- Cited by
- 310
- References
- 11
- FWCI
- 15.40
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.