The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway

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Items 201–300 of 598

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6. Differential Effects of the Swedish Mutant Amyloid Precursor Protein on β-Amyloid Accumulation and Secretion in Neurons and Nonneuronal Cells
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42. Post-transcriptional Contribution of a cAMP-dependent Pathway to the Formation of α- and β/γ-Secretases-Derived Products of βAPP Maturation in Human Cells Expressing Wild-type and Swedish Mutated βAPP
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44. Prodomain processing of Asp1 (BACE2) is autocatalytic
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45. Autosomal‐dominant Alzheimer's disease mutations at the same codon of amyloid precursor protein differentially alter Aβ production
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46. Is BACE1 a suitable therapeutic target for the treatment of Alzheimer's disease? Current strategies and future directions
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54. Binding of Inhibitors to BACE1 Affected by pH-Dependent Protonation: An Exploration from Multiple Replica Gaussian Accelerated Molecular Dynamics and MM-GBSA Calculations
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56. Niemann–Pick type C cells show cholesterol dependent decrease of APP expression at the cell surface and its increased processing through the β-secretase pathway
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