Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1

Gut microbiota, metabolites and host immunity

Rooks, M. G., & Garrett, W. S. (2016) · Nature reviews. Immunology · doi:10.1038/nri.2016.42 · Cited by 3,409

Development and function of human innate immune cells in a humanized mouse model

Rongvaux, A., Willinger, T., Martinek, J., Strowig, T., Gearty, S. V., Teichmann, L. L., Saito, Y., Marches, F., Halene, S., Palucka, A. K., et al. (2014) · Nature Biotechnology · doi:10.1038/nbt.2858 · Cited by 789

Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients

Deuse, T., Hu, X., Gravina, A., Wang, D., Tediashvili, G., De, C., Thayer, W. O., Wahl, A., Garcia, J. V., Reichenspurner, H., et al. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0016-3 · Cited by 758

Humanized mouse models for immuno-oncology research

Chuprin, J., Buettner, H., Seedhom, M. O., Greiner, D. L., Keck, J. G., Ishikawa, F., Shultz, L. D., & Brehm, M. A. (2023) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-022-00721-2 · Cited by 423

Generation of hypoimmunogenic human pluripotent stem cells

Han, X., Wang, M., Duan, S., Franco, P. J., Kenty, J. H.-R., Hedrick, P., Xia, Y., Allen, A., Ferreira, L. M. R., Strominger, J. L., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1902566116 · Cited by 363

Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge

Pardi, N., Secreto, A. J., Shan, X., Debonera, F., Glover, J., Yi, Y., Muramatsu, H., Ni, H., Mui, B. L., Tam, Y. K., et al. (2017) · Nature Communications · doi:10.1038/ncomms14630 · Cited by 352

HIV-infected T cells are migratory vehicles for viral dissemination

Murooka, T. T., Deruaz, M., Marangoni, F., Vrbanac, V. D., Seung, E., von Andrian, U. H., Tager, A. M., Luster, A. D., & Mempel, T. R. (2012) · Nature · doi:10.1038/nature11398 · Cited by 322

Sustained delivery and molecular targeting of a therapeutic monoclonal antibody to metastases in the central nervous system of mice

Wen, J., Wu, D., Qin, M., Liu, C., Wang, L., Xu, D., Vinters, H. V., Liu, Y., Kranz, E., Guan, X., et al. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0434-z · Cited by 108

Nanoformulations of Rilpivirine for Topical Pericoital and Systemic Coitus-Independent Administration Efficiently Prevent HIV Transmission

Kovarova, M., Council, O. D., Date, A. A., Long, J. M., Nochii, T., Belshan, M., Shibata, A., Vincent, H., Baker, C. E., Thayer, W. O., et al. (2015) · PLOS Pathogens · doi:10.1371/journal.ppat.1005075 · Cited by 77

Development of humanized mouse and rat models with full-thickness human skin and autologous immune cells

Agarwal, Y., Beatty, C., Ho, S., Thurlow, L., Das, A., Kelly, S., Castronova, I., Salunke, R., Biradar, S., Yeshi, T., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-71548-z · Cited by 38

Human allograft rejection in humanized mice: a historical perspective

Brehm, M. A., & Shultz, L. D. (2012) · Cellular & Molecular Immunology · doi:10.1038/cmi.2011.64 · Cited by 30

What we are learning on HTLV-1 pathogenesis from animal models

Dodon, M. D., Villaudy, J., Gazzolo, L., Haines, R., & Lairmore, M. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00320 · Cited by 23

HTLV-1 Infection and Neuropathogenesis in the Context of Rag1-/-γc-/- (RAG1-Hu) and BLT Mice

Ginwala, R., Caruso, B., Khan, Z. K., Pattekar, A., Chew, G. M., Corley, M. J., Loonawat, R., Jacobson, S., Sreedhar, S., Ndhlovu, L. C., et al. (2017) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-017-9740-y · Cited by 17

Epstein-Barr virus infection promotes T cell dysregulation in a humanized mouse model of multiple sclerosis

Allanach, J. R., Fettig, N. M., Hardman, B. K., Rosen, A. R., Fan, V., Chung, C., Goldberg, E. J., Morse, Z. J., Shanina, I., Vorobeychik, G., et al. (2025) · Science Advances · doi:10.1126/sciadv.adu5110 · Cited by 14