The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Biomimetic proteolipid vesicles for targeting inflamed tissues
Open accessAbstract
A multitude of micro- and nanoparticles have been developed to improve the delivery of systemically administered pharmaceuticals, which are subject to a number of biological barriers that limit their optimal biodistribution. Bioinspired drug-delivery carriers formulated by bottom-up or top-down strategies have emerged as an alternative approach to evade the mononuclear phagocytic system and facilitate the transport across the endothelial vessel wall. Here, we describe a method that leverages the advantages of bottom-up and top-down strategies to incorporate proteins derived from the leukocyte plasma membrane into lipid nanoparticles. The resulting proteolipid vesicles - which we refer to as leukosomes - retained the versatility and physicochemical properties typical of liposomal formulations, preferentially targeted inflamed vasculature, enabled the selective and effective delivery of dexamethasone to inflamed tissues, and reduced phlogosis in a localized model of inflammation.
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Nanoparticle biointerfacing by platelet membrane cloaking
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He, C., Zheng, S., Luo, Y., & Wang, B. (2018) · Theranostics · doi:10.7150/thno.21945 · Cited by 1,249
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Fang, R. H., Gao, W., & Zhang, L. (2023) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-022-00699-x · Cited by 980
Recent progress in drug delivery
Li, C., Wang, J., Wang, Y., Gao, H., Wei, G., Huang, Y., Yu, H., Gan, Y., Wang, Y., Mei, L., et al. (2019) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2019.08.003 · Cited by 818
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Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic
Weiss, C., Carriere, M., Fusco, L., Capua, I., Regla-Nava, J. A., Pasquali, M., Scott, J. A., Vitale, F., Unal, M. A., Mattevi, C., et al. (2020) · ACS Nano · doi:10.1021/acsnano.0c03697 · Cited by 601
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Metadata
- Authors
- Molinaro, R., Corbo, C., Martinez, J. O., Taraballi, F., Evangelopoulos, M., Minardi, S., Yazdi, I. K., Zhao, P., De Rosa, E., Sherman, M. B., De Vita, A., Toledano Furman, N. E., Wang, X., Parodi, A., & Tasciotti, E.
- Venue
- Nature Materials
- Published
- 2016-05-23
- Volume
- 15
- Issue
- 9
- Pages
- 1037-1046
- ISSN
- 1476-1122 (ISSN-L)
- 1476-4660
- OpenAlex
- W2406375428
- Cited by
- 451
- References
- 42
- FWCI
- 14.28
- Type
- journal article
- Language
- en
- Open access
- green
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- Molinaro, R., Corbo, C., Martinez, J. O., Taraballi, F., Evangelopoulos, M., Minardi, S., Yazdi, I. K., Zhao, P., De Rosa, E., Sherman, M. B., De Vita, A., Toledano Furman, N. E., Wang, X., Parodi, A., & Tasciotti, E. (2016). Biomimetic proteolipid vesicles for targeting inflamed tissues. Nature Materials. https://doi.org/10.1038/nmat4644
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