A public genome-scale lentiviral expression library of human ORFs
Yang, Xiaoping, Boehm, Jesse S, Yang, Xinping, Salehi-Ashtiani, Kourosh, Hao, Tong, Shen, Yun, Lubonja, Rakela, Thomas, Sapana R, Alkan, Ozan, Bhimdi, Tashfeen, Green, Thomas M, Johannessen, Cory M, Silver, Serena J, Nguyen, Cindy, Murray, Ryan R, Hieronymus, Haley, Balcha, Dawit, Fan, Changyu, Lin, Chenwei, Ghamsari, Lila, Vidal, Marc, Hahn, William C, Hill, David E, Root, David E·2011·Nature Methods
Cited by (572)
Items 401–500 of 572
- A systematic genotype-phenotype map for missense variants in the human intellectual disability-associated gene GDI1Rachel A. Silverstein, Song Sun, Marta Verby, Jochen Weile, Yingzhou Wu, Marinella Gebbia, Iosifina Fotiadou, Julia Kitaygorodsky, Frederick P. Roth · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Proteome-scale tagging and functional screening in mammalian cells by ORFtagFilip Nemčko, Moritz Himmelsbach, Vincent Loubière, Ramesh Yelagandula, Michaela Pagani, Nina Fasching, Julius Brennecke, Ulrich Elling, Alexander Stark, Stefan Ludwig Ameres · 2024 · Nature Methods
- Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma TumorigenesisTao Xu, Honglai Zhang, Sung Soo Park, Sriram Venneti, Rork D. Kuick, Kimberly Ha, Lowell Evan Michael, Mariarita Santi, Chiyoko Uchida, Takafumi Uchida et al. · 2017 · Neoplasia
- Sodium-dependent phosphate transporter PiT1/SLC20A1 as the receptor for the endogenous retroviral envelope syncytin-B involved in mouse placenta formationGuillaume Mousseau, Noémie Préault, Sylvie Souquère, Caroline Bireau, Patricia Cassonnet, Agathe Bacquin, Laurent Beck, Gérard Pierron, Yves Jacob, Anne Dupressoír et al. · 2024 · Journal of Virology
- A forward genetic screen identifies modifiers of rocaglate responsivenessLeo L. Shen, Lauren Pugsley, Regina Cencic, HanChen Wang, Francis Robert, Sai Kiran Naineni, Ananya Sahni, Geneviève Morin, Wenhan Zhang, Anastasia Nijnik et al. · 2021 · Scientific Reports
- Engineering a highly sensitive biosensor for abscisic acid in mammalian cellsSeo Woo Kim, Kübra Alci, Femke Van Gaever, Yasmine Driege, Keylla U. Bicalho, Geert Goeminne, Claude Libert, Alain Goossens, Rudi Beyaert, Jens Staal · 2022 · FEBS Letters
- Inducible and Reversible Lentiviral and Recombination Mediated Cassette Exchange (RMCE) Systems for Controlling Gene ExpressionDavid C. Bersten, Adrienne E. Sullivan, Dian Li, Veronica L. D. Bhakti, Stephen J. Bent, Murray L. Whitelaw · 2015 · PLoS ONE
- Distinct genetic pathways define pre-leukemic and compensatory clonal hematopoiesis in Shwachman-Diamond syndromeAlyssa L. Kennedy, Kasiani C. Myers, James R. Bowman, Christopher James Gibson, Nicholas D. Camarda, Elissa Furutani, Gwen M. Muscato, Robert H. Klein, Kaitlyn Ballotti, Shanshan Liu et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Maintenance of p-eIF2α levels by the eIF2B complex is vital for colorectal cancerIvana Paskov Škapik, Chiara Giacomelli, Sarah Hahn, Hanna Deinlein, Peter Gallant, Mathias Diebold, Josep Biayna, Anne Hendricks, Leon Olimski, Christoph Otto et al. · 2025 · The EMBO Journal
- ZNF280A links DNA double-strand break repair to human 22q11.2 distal deletion syndromeThomas L. Clarke, Hyo Min Cho, Ilaria Ceppi, Boya Gao, Tribhuwan Yadav, Giórgia Gobbi da Silveira, Ruben Boon, Bárbara Martínez-Pastor, Nana Yaa A. Amoh, Belen Machin et al. · 2025 · Nature Cell Biology
- TGFBR3 supports anoikis through suppressing ATF4 signalingYu-Jhen Hsu, Yih-Jia Yin, Kai-Feng Tsai, Cian-Chun Jian, Zi-Wen Liang, Chien-Yu Hsu, Chun‐Chao Wang · 2022 · Journal of Cell Science
- Gaining New Insights into Fundamental Biological Pathways by Bacterial Toxin-Based Genetic ScreensSonghai Tian, Nini Zhou · 2023 · Bioengineering
- Narrowing the focus: a toolkit to systematically connect oncogenic signaling pathways with cancer phenotypesKatherine R. Singleton, Kris C. Wood · 2016 · Genes & Cancer
- Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutationsJonathan S. Brammeld, Mia Petljak, Iñigo Martincorena, Steven P. Williams, Luz García‐Alonso, Alba Dalmases, Beatríz Bellosillo, Carla Daniela Robles‐Espinoza, Stacey Price, Syd Barthorpe et al. · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
- Up, down, and out: optimized libraries for CRISPRa, CRISPRi, and CRISPR-knockout genetic screensKendall R Sanson, Ruth E. Hanna, Mudra Hegde, Katherine F. Donovan, Christine Strand, Meagan E. Sullender, Emma W Vaimberg, Amy B. Goodale, David E. Root, Federica Piccioni et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Codon Usage and Amino Acid Identity Are Major Determinants of MRNA Stability in HumansMegan E. Forrest, Ashrut Narula, Thomas J. Sweet, Daniel Arango, Gavin K. Hanson, James Ellis, Shalini Oberdoerffer, Jeff Coller, Olivia S. Rissland · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- LAT1 supports mitotic progression through Golgi unlinking in an amino acid transport activity-independent mannerSakura Yanagida, Ryuzaburo Yuki, Youhei Saito, Yuji Nakayama · 2024 · Journal of Biological Chemistry
- Cytidine diphosphate diacylglycerol synthase 2 is a synthetic lethal target in mesenchymal-like cancersTim Arnoldus, Alex v. Vliet, Onno B. Bleijerveld, Adriaan F. H. de Groot, Qinglin Piao, Niek Blomberg, Désirée Schatton, Jing Ming Dong, Susan E. van Hal-van Veen, Rolf Harkes et al. · 2025 · Nature Genetics
- Proteome-wide copy-number estimation from transcriptomicsSweatt, Andrew J, Griffiths, Cameron D, Groves, Sarah M, Paudel, B Bishal, Wang, Lixin, Kashatus, David F, Janes, Kevin A · 2024 · Molecular Systems Biology
- The Development of RNA-KISS, a Mammalian Three-Hybrid Method to Detect RNA–Protein Interactions in Living Mammalian CellsIrma H. Lemmens, Sander Jansen, Steffi de Rouck, Anne-Sophie de Smet, Dieter Defever, Johan H. Neyts, Kai Dallmeier, Jan H. Tavernier · 2020 · Journal of Proteome Research
- Persistent Activation of mRNA Translation by Transient Hsp90 InhibitionPeter Tsvetkov, Timothy J. Eisen, Sven U. Heinrich, Zarina Brune, Erinc Hallacli, Gregory A. Newby, Can Kayatekin, David Pincus, Susan Lee Lindquist · 2020 · Cell Reports
- Modeling DNA trapping of anticancer therapeutic targets using missense mutations identifies dominant synthetic lethal interactionsAkil Hamza, Leanne Amitzi, Lina Ma, Maureen R M Driessen, Nigel J. O’Neil, Philip Hieter · 2021 · Proceedings of the National Academy of Sciences
- An Unbiased Functional Genetics Screen Identifies Rare Activating ERBB4 MutationsDeepankar Chakroborty, Veera K. Ojala, Anna M. Knittle, Jasmin Drexler, Mahlet Z. Tamirat, Regina Ruzicka, Karin Bosch, Johanna Woertl, Susanne Schmittner, Laura L. Elo et al. · 2022 · Cancer Research Communications
- Use of Autoreactive Antibodies in Blood of Patients with Pancreatic Intraductal Papillary Mucinous Neoplasms (IPMN) for Grade Distinction and Detection of MalignancyNiall Brindl, Henning Boekhoff, Andrea S. Bauer, Matthias M. Gaida, Hien T. Dang, Jörg Kaiser, Jörg D. Hoheisel, Klaus Felix · 2022 · Cancers
- A unified genetic perturbation language for human cellular programmingAustin Hartman, Oliver Takacsi-Nagy, Courtney Kernick, Nicole E. Theberath, Johnathan Lu, Lujing Wu, Michelle Mantilla, Siddhesh Mittra, Alison K. McClellan, Nicole Johnson et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Failure to repair damaged NAD(P)H blocks de novo serine synthesis in human cellsAdhish S. Walvekar, Marc O. Warmoes, Dean Cheung, Tim Sikora, Najmesadat Seyedkatouli, Gemma Gomez‐Giro, Sebastián Perrone, Lisa Dengler, François Unger, Bruno F. R. Santos et al. · 2025 · Cellular & Molecular Biology Letters
- A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactorCharlotte A. Stoneham, Simon Langer, Paul D. De Jesus, Jacob M. Wozniak, John D. Lapek, Thomas J. Deerinck, Andrea Thor, Lars Pache, Sumit K. Chanda, David J. Gonzalez et al. · 2021 · PLoS Pathogens
- A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology2025
- Finding a needle in a haystack: functional screening for novel targets in cancer immunology and immunotherapiesYi Du, Yang Yang, Bohao Zheng, Qian Zhang, Shengtao Zhou, Linjie Zhao · 2025 · Oncogene
- Proximal partners of the organellar N-terminal acetyltransferase NAA60: insights into Golgi structure and transmembrane protein topologySebastián Tanco, Veronique Jonckheere, Arun Kumar Tharkeshwar, Annelies Bogaert, Kris Gevaert, Wim G. Annaert, Petra Van Damme · 2025 · Open Biology
- U2AF1 mutations rescue deleterious exon skipping induced by KRAS mutationsDavid M. Walter, Katherine Cho, Smruthy Sivakumar, Daniel Denney, Iris TIENLYNN. Lee, Anders B. Dohlman, Jakob M. Heinz, Ethan Shurberg, Kevin X. Jiang, Akansha A. Gupta et al. · 2026 · Nature Genetics
- Chemical Dimerizers in Three-Hybrid Systems for Small Molecule–Target Protein ProfilingDries J.H. De Clercq, Jan H. Tavernier, Sam Lievens, Serge Van Calenbergh · 2016 · ACS Chemical Biology
- Identification of Novel Kinases of Tau Using Fluorescence Complementation Mass Spectrometry (FCMS)Der‐Shyang Kao, Yanyan Du, Andrew G. DeMarco, Sehong Min, Mark C. Hall, Jean‐Christophe Rochet, W. Andy Tao · 2022 · Molecular & Cellular Proteomics
- A Proteomic Survey of the Cystic Fibrosis Transmembrane Conductance Regulator SurfaceomeMelissa Iazzi, Sara Sadeghi, Gagan D. Gupta · 2023 · International Journal of Molecular Sciences
- Cell-Int: a cell–cell interaction assay to identify native membrane protein interactionsThibaud Aymoz-Bressot, Marie Canis, Florian Meurisse, Anne Wijkhuisen, Benoı̂t Favier, Guillaume Mousseau, Anne Dupressoír, Thiérry Heidmann, Agathe Bacquin · 2024 · Life Science Alliance
- Pooled analysis of radiation hybrids identifies loci for growth and drug action in mammalian cellsArshad H. Khan, Andy Lin, Richard T. Wang, Joshua S. Bloom, Kenneth L. Lange, Desmond Smith · 2020 · Genome Research
- Salvage of Ribose from Uridine or RNA Supports Glycolysis when Glucose is LimitingAlexis A. Jourdain, Owen S. Skinner, Akinori Kawakami, Russel P. Goodman, Hongying Shen, Lajos Vince Kemény, Lena M. Joesch-Cohen, Matthew G. Rees, Jennifer A. Roth, David E. Fisher et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Modeling Human Genetic Disorders with CRISPR Technologies in XenopusHelen Rankin Willsey, Matthew Guille, Robert M. Grainger · 2021 · Cold Spring Harbor Protocols
- A temporal (phospho-)proteomic dataset of neurotrophic receptor tyrosine kinase signalling in neuroblastomaStephanie Maher, Kieran J. Wynne, Vadim Zhernovkov, Melinda Halász · 2024 · Scientific Data
- Membrane-wide screening identifies potential tissue-specific determinants of SARS-CoV-2 tropismRavi K. Dinesh, Chengkun Wang, Yuanhao Qu, Arjun Rustagi, Henry C. Cousins, James R. Zengel, Xiaotong Wang, Trisha R. Barnard, William A. Johnson, Guangxue Xu et al. · 2025 · PLoS Pathogens
- C9orf72 ALS ‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granulesSaygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vı́lchez · 2025 · FEBS Letters
- DOT1L activity limits transcription elongation velocity and favors RNAPII pausing to facilitate mutagenesis by AIDPoorani Ganesh Subramani, Noé Seija, Jana Ridani, Jonathan Boulais, Paul A. Donnelly, Mélanie Provencher, Halil Bagci, Christian Poitras, Jean‐François Côté, François Robert et al. · 2026 · Nature Communications
- Analysis of the Repertoires of Circulating Autoantibodies’ Specificities as a Tool for Identification of the Tumor-Associated Antigens: Current Problems and SolutionsPavel V. Belousov · 2021 · Biochemistry (Moscow)
- Liver cancer cells with nuclear MET overexpression release translation regulatory protein‐enriched extracellular vesicles exhibit metastasis promoting activitySze Keong Tey, Samuel W. K. Wong, Cherlie Lot Sum Yeung, Jason Ying Ki Li, Xiaowen Mao, Clive Yik‐Sham Chung, Judy Wai Ping Yam · 2022 · Journal of Extracellular Biology
- De Novo Multi-Omics Pathway Analysis Designed for Prior Data Independent Inference of Cell Signaling PathwaysVaparanta, Katri, Merilahti, Johannes A.M., Ojala, Veera K., Elenius, Klaus · 2024 · Molecular & Cellular Proteomics
- Genome-Wide CRISPRi/a Screening in an In Vitro Coculture Assay of Human Immune Cells with Tumor CellsJialing Zhang, Stephan Stanislaw Späth, Samuel G. Katz · 2019 · Methods in molecular biology
- Strain-specific disruption of interferon-stimulated N-myc and STAT interactor (NMI) function by Toxoplasma gondii type I ROP18 in human cellsJing Xia, Matthew L. Blank, Li-Juan Zhou, Shuizhen Wu, Hong‐Juan Peng, Jon P. Boyle · 2020 · Parasitology
- A Head and Neck Squamous Cell Carcinoma Model to Study and Target HPV Replication and TranscriptionMichael R. Evans, Christian T. Fontan, Claire D. James, Xu Wang, Iain M. Morgan, Molly L. Bristol · 2019 · Preprints.org
- DeSUMOylating isopeptidase 1 participates in the faithful chromosome segregation and vincristine sensitivityYuki Ikeda, Ryuzaburo Yuki, Youhei Saito, Yuji Nakayama · 2024 · The FASEB Journal
- Evaluating the CRP Interactome: Insights into Possible Novel Roles in Cellular Signaling and TumorigenicityAlison Gerhardt, Dlen Nanakaliy, Harnish D. Shah, Syed Sarfaraz, Charlotte Madigan, Makenna Downing, Robert P. Elliott, Rafid Dipto, Bella Vrapciu, Joseph W. Noetzel et al. · 2025 · Current Issues in Molecular Biology
- EZHIP in Pediatric Brain Tumors: From Epigenetic Mimicry to Therapeutic VulnerabilitiesTiziana Servidei, Serena Gentile, Alessandro Sgambato, Antonio Ruggiero · 2026 · International Journal of Molecular Sciences
- Context-dependent synthetic lethality — an emerging precision therapeutic approachLiang Chang, Katharin L. Shaw, Francisca Vázquez, William R. Sellers · 2026 · Nature reviews. Cancer
- Proteomic applications in identifying protein-protein interactionsBenjamin T. Veenstra, Timothy D. Veenstra · 2023 · Advances in protein chemistry and structural biology
- pERK transition–induced directional mode switching promotes epithelial tumor cell migrationHong-Li Yu, Guanli Xiao, Ming‐Yao Gu, Liting Zhang, Ming Xia, Shimin Mo, Yuying Zhao, Chaoliang Wei · 2024 · Proceedings of the National Academy of Sciences
- Quantification of cyclin–CDK dissociation constants using FCCS with green and near-infrared fluorescent proteinsAika Toyama, Yuhei Goto, Y Yamauchi, Hironori Sugiyama, Yohei Kondo, Atsushi Mochizuki, Kazuhiro Aoki · 2025 · Journal of Cell Science
- SMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activityGarrett W. Cooper, Benjamin P. Lee, Won Jun Kim, Yongdong Su, Victor Z. Chen, Eliseo Salas, Xiaoping Yang, Robert E. Lintner, Federica Piccioni, Andrew O. Giacomelli et al. · 2026 · Nature Communications
- Mapping regulators of cell fate determination: Approaches and challengesAditya Kumar, Prashant Mali · 2020 · APL Bioengineering
- V-Src delocalizes Aurora B by suppressing Aurora B kinase activity during monopolar cytokinesis.Ryoko Ota, Takumi Watanabe, Yuuki Wazawa, Hiroki Kuwajima, Takuya Honda, Shuhei Soeda, Youhei Saito, Ryuzaburo Yuki, Yasunori Fukumoto, N. Yamaguchi et al. · 2023 · Cellular Signalling
- Tools and Model Systems to Study Nerve-Cancer InteractionsPeter L. Wang, Nicole A. Lester, Jimmy A. Guo, Jennifer Su, Carina Shiau, William L. Hwang · 2023 · Springer eBooks
- Computational ProteomicsDebasree Sarkar, Sudipto Saha · 2016 · Springer eBooks
- SOX2-phosphorylation toggles a bistable differentiation-switch in squamous cell carcinomaSteven A. Hoang-Phou, Ana Sastre-Perona, Matteo Abbruzzese, Zhe Ying, Jasmin M. Siegle, Beatriz Aranda-Orgillés, Pedro P. Rocha, Iannis Aifantis, Jane A. Skok, Slobodan Beronja et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- A quantitative mapping approach to identify direct interactions within complexomesPhilipp Trepte, Christopher Secker, Soon Gang Choi, Julien Olivet, Eduardo Silva Ramos, Patricia Cassonnet, Sabrina Golusik, Martina Zenkner, Stephanie Beetz, Marcel Sperling et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- A compendium of Amplification-Related Gain Of Sensitivity (ARGOS) genes in human cancerVerónica Rendo, Michaël Schubert, Nicholas Khuu, Maria F. Suárez Peredo Rodríguez, Kaimeng Huang, Michelle L. Swift, Yizhou Joseph He, Johanna Zerbib, Ross Smith, Jonne A. Raaijmakers et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- An OSMR-CLIC1 cross talk drives key oncogenic pathways in glioblastomaAmir Hossein Mansourabadi, Dianbo Qu, Francesca Cianci, Jamie D. Snider, Kamaldeep Randhawa, Laura Raco, Max Kotlyar, Mohammad Al Ayach, Guido Rey, Shridhar Sanghvi et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Dengue Virus NS1 Binds Ephrin B1 to Trigger Endothelial DysfunctionFelix Pahmeier, Sabrina Hammond, Charlotte Flory, Xinyi Feng, S. Lee, Erika Vanessa Jiménez-Posada, Elias Michael Duarte, Jaime Andrés Cardona-Ospina, Aquena H. Ball, Nharae E. Lee et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Biological Activity Characterization of the Diagnostically Relevant Human Papillomavirus 16 E1C RNAChristy Susan Varghese, Rainer D. Will, Claudia Tessmer, Ilse Hofmann, Bernd Heßling, Michael Pawlita, Daniela Höfler · 2021 · Microbiology Research
- ER-liquid condensate contacts sequester FAM134B/C and RhoA to govern cell morphologyNatalia Jiménez-Moreno, Arianna Karageorgiou, Katie Winnington-Ingram, Jimi C. Wills, Chinmayi Pednekar, Melina Overhoff, Katherine Paine, Matthew Pearson, Lukas Gerasimavicius, Ann P. Wheeler et al. · 2026 · Molecular Cell
- A High‐Throughput Multi Well Plate–Based Approach for the Combined Expression, Export, and Assay of Recombinant ProteinsKaren Baker, Daniel P. Mulvihill · 2025 · Current Protocols
- The human endogenous retroviral envelope HEMO protein interacts with BACE2: Novel partnership acquired in the primate lineageAnthony Béguin, Marianne Chasseriaud, G A Hollaender, Yves Jacob, Guillaume Mousseau, Thiérry Heidmann, Odile Heidmann · 2025 · Proceedings of the National Academy of Sciences
- Hyaluronic acid regulates cellular UDP-GlcNAc levels through CD44 to affect glycosylation and cell biological functionsYue Wang, Tomoya Isaji, Tiangui Wu, Takuro Ono, Tsukushi Saito, Yoshiyuki Kuroda, Tomohiko Fukuda, Jianguo Gu · 2025 · Journal of Biological Chemistry
- Targeting the splicing factor CWC22 induces mitotic slippage through repression of BubR1 expression and CDK1 activity in cancer cellsRyuzaburo Yuki, Youhei Saito, Yuji Nakayama · 2026 · Journal of Biological Chemistry
- An oncostatin M receptor and chloride intracellular channel 1 crosstalk drives key oncogenic pathways in glioblastomaAmir Hossein Mansourabadi, Dianbo Qu, Francesca Cianci, Jamie D. Snider, Kamaldeep Randhawa, Laura Raco, Max Kotlyar, Mohammad Al Ayach, Guido Rey, Shridhar Kiran Sanghvi et al. · 2026 · Signal Transduction and Targeted Therapy
- Screening for Host Factors Directly Interacting with RSV Protein: MicrofluidicsSarit Kipper, Dorit Avrahami, Monika Bajorek, Doron Gerber · 2016 · Methods in molecular biology
- Second Generation Genome Editing Technologies in Drug DiscoveryThomas Malcolm, David A. Mitchell, Niraj Muni · 2020 · Elsevier eBooks
- Dead-Seq: Discovering Synthetic Lethal Interactions from Dead Cells GenomicsJoan Blanco-Fernández, Alexis A. Jourdain · 2023 · Methods in molecular biology
- CRISPR-Based Modular Assembly for High-Throughput Construction of a UAS-cDNA/ORF Plasmid LibrarySi Xu, Mengyu Chen, Guang Jing Chen, Si Luo, Wen Xue, Xuelian Liu, Jiwu Wang, Ping Wei · 2024 · Journal of Visualized Experiments
- Utilizing small molecules to probe and harness the proteome by pooled protein tagging with ligandable domainsKatherine E. Larrimore, Yevgeniy V. Serebrenik · 2025 · Frontiers in Pharmacology
- Cancer as a Paradigm for Translational and Clinical Biomedical ResearchCésar Serrano, George D. Demetri · 2016 · Elsevier eBooks
- Genetic and Chemical Modifiers of EGFR Dependence in Non-Small Cell Lung CancerTanaz Sharifnia · 2014 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
- Pan-cancer organoid validation of tumor outlier chromosomal amplification eventsAmeen Abdulla Salahudeen, Kanako Yuki, José Antonio Seoane, Amanda T. Mah, Amber Rae Smith, Kevin S. Kolahi, Sean de la O, Daniel James Hart, Jie Ding, Zhicheng Ma et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Human Nucleolar Protein 7 (NOL7) is required for pre-rRNA transcription and pre-18S rRNA processingMason A. McCool, Carson J. Bryant, Hannah Huang, Lisa M. Ogawa, Katherine I. Farley‐Barnes, Samuel B. Sondalle, Laura Abriola, Yulia V. Surovtseva, Susan J. Baserga · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- BiFC Magic: Shedding Light on Protein-Protein InteractionsYunlong Y. Jia, Françoise Bleicher, Samir Merabet · 2023 · Preprints.org
- Dosage Amplification Dictates Oncogenic Regulation by the NKX2-1 Lineage Factor in Lung AdenocarcinomaJohn L. Pulice, Matthew M. Meyerson · 2023 · SSRN Electronic Journal
- A missense variant effect map for the human tumour suppressor protein CHK2Marinella Gebbia, Daniel Zimmerman, Rosanna Jiang, Maria Nguyen, Jochen Weile, Roujia Li, Michelle Gavac, Nishka Kishore, Song Sun, Rick A.C.M. Boonen et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Multisite Assembly of Gateway Induced Clones (MAGIC): a flexible cloning toolbox with diverse applications in vertebrate model systemsWilliam Gillespie, Yuwen Zhang, Oscar E. Ruiz, Juan Cerda, Joshua Ortiz‐Guzman, Williamson D. Turner, Gabrielle E. Largoza, Michelle Sherman, Lili E. Mosser, Esther Fujimoto et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Quantification of Cyclin-CDK dissociation constants in living cells using fluorescence cross-correlation spectroscopy with green and near-infrared fluorescent proteinsAika Toyama, Yuhei Goto, Y Yamauchi, Hironori Sugiyama, Yohei Kondo, Atsushi Mochizuki, Kazuhiro Aoki · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Transmembrane CLIC1 sustains EGFRvIII–STAT3 oncogenic signaling in Glioblastoma through interaction with OSMRArezu Jahani‐Asl, Amir Hossein Mansourabadi, Kamaldeep Randhawa, Jamie D. Snider, Dianbo Qu, Francesca Cianci, Max Kotlyar, Guido Rey, Laura Raco, Dylan E Burger et al. · 2025 · Research Square
- Host mRNA 3’-end processing machinery are critical binding partners during dengue virus infectionMin Jie Alvin Tan, Ahmad Nazri Mohamed Naim, Yan Ting Lim, Radoslaw Mikolaj Sobota, Martin Lloyd Hibberd, Subhash G. Vasudevan · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- A simple method for analyzing competitive growth of multiple cell types in xenograft tumorsTiffany A. Melhuish, Sara J. Adair, Olivia S Pemberton, Todd W. Bauer, David Wotton · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Cas12a-based combinatorial knockout screens define the genetic architecture of the DNA damage responseSamuel B. Hayward, Alina Vaitsiankova, Tomás Lama-Díaz, Juihsuan Chou, Angelo Taglialatela, Jen‐Wei Huang, Yodharaudshani Wijesekarahanthi, Joshua R. Heyza, Giuseppe Leuzzi, Chuanyuan Chen et al. · 2026 · Nature Biotechnology
- A multiscale functional map of somatic mutations in cancer integrating protein structure and network topologyZhang, Yingying, Leung, Alden K., Kang, Jin Joo, Sun, Yu, Wu, Guanxi, Li, Le, Sun, Jiayang, Cheng, Lily, Qiu, Tian, Zhang, Junke et al. · 2023
- Exploration of Panviral Proteome: High-Throughput Cloning and Functional Implications in Virus-hostXiaofang Bian, Andrea L. Throop, Lusheng Song, Lerys Del Moral, Jin Park, Michael Fiacco, Jason C. Steel, Preston D. Hunter, Justin M. Saul, Jie Wang et al. · 2014
- METHOD Open AccessLasse Maretty, Jonas A. Sibbesen, Anders Krogh · 2014
- Understanding the Genetic Mechanisms of Cancer Drug Resistance Using GenomicApproaches Hu, Zemin Zhang · 2016
- Synthetic lethality and chemoresistance in cancerKimberly Maxfield, Angelique W. Whitehurst · 2015 · Cambridge University Press eBooks
- Kruppel-like factor 4 (KLF4) regulates protumorigenic signaling in triple-negative breast cancer (TNBC) cellsSriganesh B. Sharma · 2015 · The Research Repository @ WVU (West Virginia University)
- Exploring Context-Specific Genetic Vulnerabilities in Human Cancer Cell LinesEun Jee Koh · 2016 · TSpace (University of Toronto)
- Development and Application of High-throughput Chemical Genomic Screens for Functional Studies of Cancer TherapeuticsKahlin Cheung-Ong · 2013 · TSpace (University of Toronto)
- Identification and Validation of Driver Kinases from Next-Generation Sequencing DataAndri Leonidou, Barrie Peck, Rachael Natrajan · 2017 · Methods in molecular biology
- Revision 1: MCR-15-0130 Patient mutation directed shRNA screen uncovers novel bladder tumor growth suppressorsJonathan A. Hensel, Jason E. Duex, Charles R. Owens, Garrett Marc Dancik, Michael G. Edwards, Henry F. Frierson, Dan Theodorescu · 2015