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Cited by 472

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Dual-objective STORM reveals three-dimensional filament organization in the actin cytoskeleton

Open access
Xu, Ke, Babcock, Hazen P, Zhuang, Xiaowei·2012·Nature Methods

Abstract

By combining astigmatism imaging with a dual-objective scheme, we improved the image resolution of stochastic optical reconstruction microscopy (STORM) and obtained <10-nm lateral resolution and <20-nm axial resolution when imaging biological specimens. Using this approach, we resolved individual actin filaments in cells and revealed three-dimensional ultrastructure of the actin cytoskeleton. We observed two vertically separated layers of actin networks with distinct structural organizations in sheet-like cell protrusions.

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Metadata

Authors
Xu, K., Babcock, H. P., & Zhuang, X.
Venue
Nature Methods
Published
2012-01-08
Volume
9
Issue
2
Pages
185-188
ISSN
  • 1548-7091 (ISSN-L)
  • 1548-7105
OpenAlex
W2034713721
Cited by
472
References
2
FWCI
21.65
Type
journal article
Language
en
Open access
green

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