The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Two-photon optogenetics of dendritic spines and neural circuits
Open accessAbstract
We demonstrate a two-photon optogenetic method that generates action potentials in neurons with single-cell precision, using the red-shifted opsin C1V1T. We applied the method to optically map synaptic circuits in mouse neocortical brain slices and to activate small dendritic regions and individual spines. Using a spatial light modulator, we split the laser beam onto several neurons and performed simultaneous optogenetic activation of selected neurons in three dimensions.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The excitatory neuronal network of the C2 barrel column in mouse primary somatosensory cortex
Lefort, S., Tomm, C., Floyd Sarria, J.-C., & Petersen, C. C. H. (2009) · Neuron · doi:10.1016/j.neuron.2008.12.020 · Cited by 875
Mattis, J., Tye, K. M., Ferenczi, E. A., Ramakrishnan, C., O'Shea, D. J., Prakash, R., Gunaydin, L. A., Hyun, M., Fenno, L. E., Gradinaru, V., et al. (2012) · Nature Methods · doi:10.1038/nmeth.1808 · Cited by 780
Self-citationDensity of neurons and synapses in the cerebral cortex of the mouse
Schüz, A., & Palm, G. (1989) · Journal of Comparative Neurology · doi:10.1002/cne.902860404 · Cited by 376
The columnar and laminar organization of inhibitory connections to neocortical excitatory cells
Kätzel, D., Zemelman, B. V., Buetfering, C., Wölfel, M., & Miesenböck, G. (2011) · Nature Neuroscience · doi:10.1038/nn.2687 · Cited by 241
Cited by
Flow of cortical activity underlying a tactile decision in mice
Guo, Z. V., Li, N., Huber, D., Ophir, E., Gutnisky, D., Ting, J. T., Feng, G., & Svoboda, K. (2014) · Neuron · doi:10.1016/j.neuron.2013.10.020 · Cited by 715
Integration of optogenetics with complementary methodologies in systems neuroscience
Kim, C. K., Adhikari, A., & Deisseroth, K. (2017) · Nature reviews. Neuroscience · doi:10.1038/nrn.2017.15 · Cited by 690
Self-citationVisual stimuli recruit intrinsically generated cortical ensembles
Miller, J.-E. K., Ayzenshtat, I., Carrillo-Reid, L., & Yuste, R. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1406077111 · Cited by 288
Self-citationOpening Holes in the Blanket of Inhibition: Localized Lateral Disinhibition by VIP Interneurons
Karnani, M. M., Jackson, J., Ayzenshtat, I., Hamzehei Sichani, A., Manoocheri, K., Kim, S., & Yuste, R. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.3646-15.2016 · Cited by 236
Self-citationSparse recurrent excitatory connectivity in the microcircuit of the adult mouse and human cortex
Seeman, S. C., Campagnola, L., Davoudian, P. A., Hoggarth, A., Hage, T. A., Bosma-Moody, A., Baker, C. A., Lee, J. H., Mihalas, S., Teeter, C., et al. (2018) · eLife · doi:10.7554/elife.37349 · Cited by 183
Metadata
- Authors
- Packer, A. M., Peterka, D. S., Hirtz, J. J., Prakash, R., Deisseroth, K., & Yuste, R.
- Venue
- Nature Methods
- Published
- 2012-11-11
- Volume
- 9
- Issue
- 12
- Pages
- 1202-1205
- ISSN
- 1548-7091 (ISSN-L)
- 1548-7105
- OpenAlex
- W2015520158
- Cited by
- 279
- References
- 4
- FWCI
- 8.17
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Two-photon optogenetics of dendritic spines and neural circuits. https://app.cochat.ai/papers/10.1038/nmeth.2249
- The paper
- Packer, A. M., Peterka, D. S., Hirtz, J. J., Prakash, R., Deisseroth, K., & Yuste, R. (2012). Two-photon optogenetics of dendritic spines and neural circuits. Nature Methods. https://doi.org/10.1038/nmeth.2249
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
