Integration of optogenetics with complementary methodologies in systems neuroscience

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Optogenetics in neural systems

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iDISCO: A Simple, Rapid Method to Immunolabel Large Tissue Samples for Volume Imaging

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Multimodal fast optical interrogation of neural circuitry

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Optogenetic stimulation of a hippocampal engram activates fear memory recall

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Neural substrates of awakening probed with optogenetic control of hypocretin neurons

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Neuron-type-specific signals for reward and punishment in the ventral tegmental area

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Input-specific control of reward and aversion in the ventral tegmental area

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Amygdala circuitry mediating reversible and bidirectional control of anxiety

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Optogenetics: 10 years of microbial opsins in neuroscience

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Concurrent activation of striatal direct and indirect pathways during action initiation

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Evoked axonal oxytocin release in the central amygdala attenuates fear response

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Sensitive red protein calcium indicators for imaging neural activity

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Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

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Tuning arousal with optogenetic modulation of locus coeruleus neurons

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Creating a False Memory in the Hippocampus

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An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology

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Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing

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Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections

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Choice-specific sequences in parietal cortex during a virtual-navigation decision task

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Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking

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Functional imaging of hippocampal place cells at cellular resolution during virtual navigation

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Advanced CLARITY for rapid and high-resolution imaging of intact tissues

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ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation

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Intact-brain analyses reveal distinct information carried by SNc dopamine subcircuits

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Soft, stretchable, fully implantable miniaturized optoelectronic systems for wireless optogenetics

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Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins

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Ectopic Expression of a Microbial-Type Rhodopsin Restores Visual Responses in Mice with Photoreceptor Degeneration

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Ultrafast optogenetic control

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Engram cells retain memory under retrograde amnesia

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Viral-genetic tracing of the input-output organization of a central noradrenaline circuit

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Midbrain circuits for defensive behaviour

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Temporally precise in vivo control of intracellular signalling

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Differential Control of Learning and Anxiety along the Dorsoventral Axis of the Dentate Gyrus

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Global and local fMRI signals driven by neurons defined optogenetically by type and wiring

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Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics

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Permanent genetic access to transiently active neurons via TRAP: targeted recombination in active populations

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Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics

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Hippocampal–prefrontal input supports spatial encoding in working memory

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Characterization of Engineered Channelrhodopsin Variants with Improved Properties and Kinetics

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Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures

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Wireless magnetothermal deep brain stimulation

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Diverging neural pathways assemble a behavioural state from separable features in anxiety

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Bi-stable neural state switches

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BLA to vHPC inputs modulate anxiety-related behaviors

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Light-Induced Activation of Distinct Modulatory Neurons Triggers Appetitive or Aversive Learning in Drosophila Larvae

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Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury

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Wirelessly powered, fully internal optogenetics for brain, spinal and peripheral circuits in mice

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Targeting cells with single vectors using multiple-feature Boolean logic

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Dynamics of Retrieval Strategies for Remote Memories

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Simultaneous all-optical manipulation and recording of neural circuit activity with cellular resolution in vivo

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Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin

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Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2

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eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications

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Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior

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Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri

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Bidirectional switch of the valence associated with a hippocampal contextual memory engram

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Projections from neocortex mediate top-down control of memory retrieval

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Dendritic Inhibition in the Hippocampus Supports Fear Learning

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Selective Photostimulation of Genetically ChARGed Neurons

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The Inhibitory Circuit Architecture of the Lateral Hypothalamus Orchestrates Feeding

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Basomedial amygdala mediates top-down control of anxiety and fear

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Scalable control of mounting and attack by Esr1+ neurons in the ventromedial hypothalamus

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Direct ventral hippocampal-prefrontal input is required for anxiety-related neural activity and behavior

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High-speed recording of neural spikes in awake mice and flies with a fluorescent voltage sensor

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Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala

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