Microhomology-based choice of Cas9 nuclease target sites

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

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High-throughput functional genomics using CRISPR-Cas9

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CRISPR-P 2.0: An Improved CRISPR-Cas9 Tool for Genome Editing in Plants

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Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells

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Predictable and precise template-free CRISPR editing of pathogenic variants

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Highly efficient therapeutic gene editing of human hematopoietic stem cells

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The UCSC Genome Browser database: 2018 update

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Precise Correction of the Dystrophin Gene in Duchenne Muscular Dystrophy Patient Induced Pluripotent Stem Cells by TALEN and CRISPR-Cas9

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Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy

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DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks

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Am I ready for CRISPR? A user's guide to genetic screens

Doench, J. G. (2018) · Nature Reviews Genetics · doi:10.1038/nrg.2017.97 · Cited by 452

The emerging and uncultivated potential of CRISPR technology in plant science

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A Survey of Validation Strategies for CRISPR-Cas9 Editing

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Methodologies for Improving HDR Efficiency

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Site-directed mutagenesis in Petunia × hybrida protoplast system using direct delivery of purified recombinant Cas9 ribonucleoproteins

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Massively parallel profiling and predictive modeling of the outcomes of CRISPR/Cas9-mediated double-strand break repair

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Reversion of FMR1 methylation and silencing by editing the triplet repeats in Fragile X iPSC-derived neurons

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Assembly of CRISPR ribonucleoproteins with biotinylated oligonucleotides via an RNA aptamer for precise gene editing

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Microhomologies are prevalent at Cas9-induced larger deletions

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CRISPR/Cas9-mediated genome engineering of CHO cell factories: application and perspectives

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Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in Drosophila cells

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High-purity production and precise editing of DNA base editing ribonucleoproteins

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The iCRISPR Platform for Rapid Genome Editing in Human Pluripotent Stem Cells

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Efficient genomic correction methods in human iPS cells using CRISPR–Cas9 system

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Benchmarking deep learning methods for predicting CRISPR/Cas9 sgRNA on- and off-target activities

Zhang, G., Luo, Y., Dai, X., & Dai, Z. (2023) · Briefings in Bioinformatics · doi:10.1093/bib/bbad333 · Cited by 47

Interleukin 27 (IL-27) productions in the liver microenvironment confer an immunosuppressive role and enhance hepatitis B viral persistence

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