Multiplexed analysis of chromosome conformation at vastly improved sensitivity

Davies, James O J, Telenius, Jelena M, McGowan, Simon J, Roberts, Nigel A, Taylor, Stephen, Higgs, Douglas R, Hughes, Jim R·2016·Nature Methods

Cited by (269)

Items 201–269 of 269

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  3. Evaluation and comparison of methods for recapitulation of 3D spatial chromatin structures
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  5. Systematic identification of pathogenic variants of non-small cell lung cancer in the promoters of DNA-damage repair genes
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  6. Expanding the toolbox for 3D genomics
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  7. Long-range gene regulation network of the MGMT enhancer modulates glioma cell sensitivity to temozolomide
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  8. Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C
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  9. Capture Hi-C: Characterization of chromatin contacts
    Ryan R. Davis, Mel Campbell, Yoshihiro Izumiya, Clifford G. Tepper · 2020 · Elsevier eBooks
  10. Targeted high-resolution chromosome conformation capture at genome-wide scale
    Damien J. Downes, Matthew E. Gosden, Jelena M. Telenius, Stephanie J. Carpenter, Lea Nußbaum, Sara De Ornellas, Martin J. Sergeant, Chris Q. Eijsbouts, Ron Schweßinger, Jon Kerry et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  11. Mapping 3D genome organization at nucleosome-scale with Micro-C and Region Capture Micro-C (RCMC)
    Miles K. Huseyin, Clarice K. Y. Hong, Masahiro Nagano, James A. Drayton, James M. Jusuf, Jin Yang, Varshini Ramanathan, Viraat Y. Goel, S Y Kim, Anders S. Hansen · 2026 · Nature Protocols
  12. From Identification to Function: Current Strategies to Prioritise and Follow-Up GWAS Results
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  13. Model-based analysis of chromatin interactions from dCas9-Based CAPTURE-3C-seq
    Yong Chen, Yunfei Wang, Xin Liu, Jian Xu, Michael Q. Zhang · 2020 · PLoS ONE
  14. Research progress on the three-dimensional structure of genome
    ZhengHao Li, Pengchao Li, Xiangyu Yang, Le Zhang, Jun Myoung Yu, Jingtian Zhao · 2019 · Scientia Sinica Vitae
  15. Enhancers predominantly regulate gene expression in vivo via transcription initiation
    Martin Larke, Takayuki Nojima, Jelena M. Telenius, Jacqueline A. Sharpe, Jacqueline A. Sloane-Stanley, Sue Butler, Robert A. Beagrie, Damien J. Downes, Ron Schweßinger, A. Marieke Oudelaar et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  16. Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C
    Antonia Hauth, Rafael Galupa, Nicolas Servant, Laura Villacorta, Kai Hauschulz, Joke Gerarda van Bemmel, Agnese Loda, Édith Heard · 2022 · Journal of Visualized Experiments
  17. Enhancer Arrays Regulating Developmental Genes: Sox2 Enhancers as a Paradigm
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  18. Evidence for enhancer activity in intron 1 of TNFRSF1A using CRISPR/Cas9 in human induced pluripotent stem cell-derived macrophages
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  19. A functional overlap between actively transcribed genes and chromatin insulator elements
    Lucy Cornell, C. Harrold, S. Holliman, Felice H. Tsang, M. Gosden, L. Hanssen, Rosa J. Stolper, D. Downes, D. Biggs, C. Preece et al. · 2026 · EMBO Journal
  20. MYB activity drives emergent enhancer activation and enhancer-promoter interactions in acute lymphoblastic leukemia
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  21. From Chromosome Conformation Capture to Polymer Physics and Back
    Guido Tiana, Édith Heard, Luca Giorgetti · 2017 · Elsevier eBooks
  22. Application of the 3C Method to Study the Developmental Genes in Drosophila Larvae
    Oleg V. Bylino, Airat N. Ibragimov, Filomena Anna Digilio, Ennio Giordano, Yulii V. Shidlovskii · 2022 · Frontiers in Genetics
  23. Mechanism of KIT gene regulation by GATA1 lacking the N-terminal domain in Down syndrome–related myeloid disorders
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  24. Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcription
    Fabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2023 · Cell & Bioscience
  25. Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cells.
    Jason Torres, Han Sun, Vibe Nylander, Damien J. Downes, Martijn van de Bunt, Mark I. McCarthy, Jim R. Hughes, Anna L. Gloyn · 2023 · PubMed Central
  26. Best practices for the ATAC-seq assay and its data analysis
    Haibo Liu, Rui Li, Kai Hu, Jianhong Ou, Magnolia L. Pak, Michael R. Green, Lihua Julie Zhu · 2024 · Elsevier eBooks
  27. CaptureProbe: a java tool for designing probes for capture Hi-C applications
    Ma Yun-Fei, Adeniyi C. Adeola, Sun Yan-bo, Hai‐Bing Xie, Zhang Ya-ping · 2020 · 动物学研究
  28. A base-pair view of interactions between genes and their enhancers
    Anne Onrust-van Schoonhoven, Ralph Stadhouders · 2021 · Nature
  29. MC4C: Locus-Specific Enhancer Hubs And Architectural Loop Collisions Uncovered From Single Allele DNA Topologies
    Amin Allahyar · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  30. Myeloid leukemia vulnerabilities at CTCF-enriched long noncoding RNA loci
    Michelle Shu Wen Ng, Lonneke Verboon, Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Dorit Borchert, K Schuschel, Enikő Regényi, Dirk Reinhardt, Marie‐Laure Yaspo et al. · 2021 · Research Square
  31. Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cells
    Jason Torres, Han Sun, Vibe Nylander, Damien J. Downes, Martijn van de Bunt, Mark I. McCarthy, Jim R. Hughes, Anna L. Gloyn · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  32. RNA-mediated SOX2 temporal dynamics govern dual chromatin-engagement modes at Nanog
    Bitong Li, Yew Yan Wong, Yoshiaki Kobayashi, Neftali Flores Rodriguez, Tara‐Lynne Davidson, Matthew S. Graus, Valeriia Smialkovska, Shikha Pachauri, Susav Pradhan, Xiaohui Gao et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  33. Characterizing trajectory-like chromatin architectures with Fun2
    Zhengrong Zhangding, Xuhao Liu, Jiazhi Hu · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  34. Analysis of multi-way chromatin interactions at sub-nucleosome resolution identifies synergistic nano-scale interactions within super-enhancers
    Shyam Ramasamy, Yi Zhu, Magdalena A. Karpińska, Ilya M. Flyamer, Johannes Söding, A. Marieke Oudelaar · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  35. Epigenetic Rewiring of Enhancer–Promoter Interactions in Cancer: Mechanisms and Therapeutic Implications
    Choppavarapu, Lavanya, Nosirov, Bakhtiyor, Kahn, Michael, Jin, Victor X. · 2026 · Cancers
  36. Unraveling nuclear architecture
    Nicole Rusk · 2015 · Nature Methods
  37. The impact of endogenous retroviruses on nuclear organization and gene expression
    Ramya Raviram, Pedro P. Rocha, Vincent Mingyi Luo, Emily Swanzey, Emily R. Miraldi, Edward B. Chuong, Cédric Feschotte, Richard Bonneau, Jane A. Skok · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  38. Chromatin 3D – will it make understanding of cancer transformation finally possible?
    Grażyna Drabik, Jolanta Kaszuba-Zwoińska, Zdzisław Wiśniowski, Leszek Konieczny, Irena Roterman · 2018 · Bio-Algorithms and Med-Systems
  39. Commentary: Nuclear dynamics of the Set1C subunit Spp1 prepares meiotic recombination sites for break formation
    Csaba Fillér, Lilla Hornyák, Jason Roszik · 2018 · Frontiers in Genetics
  40. Chromatin topology defines cell identity and phenotypic transition in human cancer and fungal pathogen
    Yao Chen · 2020
  41. Myeloid leukemia vulnerabilities at CTCF-enriched long noncoding RNA loci
    Michelle Shu Wen Ng, Lonneke Verboon, Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Dorit Borchert, K Schuschel, Enikő Regényi, Dirk Reinhardt, Marie‐Laure Yaspo et al. · 2021 · Research Square
  42. Correction to: Epigenetic and Transcriptional Networks Underlying Atrial Fibrillation
    2020 · Circulation Research
  43. Bioinformatics analysis of multi-omics data elucidates the primary function of Oct4 in gene regulation and pluripotency maintenance
    Le Xiong · 2022
  44. Faculty Opinions recommendation of Tissue-specific CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo.
    Amy L. Kenter · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  45. Reviewer #2 (Public Review): A genome-wide nucleosome-resolution map of promoter-centered interactions in human cells corroborates the enhancer-promoter looping model
    Arkadiy K. Golov, Alexey A. Gavrilov, Noam Kaplan · 2023 · eLife
  46. eLife Assessment: A genome-wide nucleosome-resolution map of promoter-centered interactions in human cells corroborates the enhancer-promoter looping model
    Jian Xu · 2023 · eLife
  47. A genome-wide nucleosome-resolution map of promoter-centered interactions in human cells corroborates the enhancer-promoter looping model
    Arkadiy K. Golov, Alexey A. Gavrilov, Noam Kaplan, Sergey V. Razin · 2024 · eLife
  48. Using paired-end read orientations to assess technical biases in capture Hi-C
    Peter Hansen, Hannah Blau, Jochen Hecht, Guy Karlebach, Alexander Krannich, Robin Steinhaus, Matthias Truß, Peter N. Robinson · 2024 · NAR Genomics and Bioinformatics
  49. Anti-Phase Clustering of Regulatory Factors Shapes Gene Transcription Burst
    Bitong Li, Yew Yan Wong, Neftali Flores Rodriguez, Tara Davidson, Matthew S. Graus, Valeriia Smialkovska, Hiroaki Ohishi, Angelika Feldmann, Hiroshi Ochiai, Mathias François · 2025 · SSRN Electronic Journal
  50. Sustained MYB activity drives emergent enhancer activation and precise enhancer-promoter interactions
    I‐Jun Lau, Joe R. Harman, Alastair Smith, Nicholas Denny, Nicole Jackson, Joseph C. Hamley, Paresh Vyas, James O. J. Davies, Jim R. Hughes, Nicholas T. Crump et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  51. Additional file 2 of Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcription
    Fabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2024 · Figshare
  52. Additional file 5 of Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcription
    Fabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2024 · Figshare
  53. Additional file 4 of Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcription
    Fabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2024 · Figshare
  54. Additional file 3 of Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcription
    Fabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2024 · Figshare
  55. Additional file 7 of Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcription
    Fabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2024 · Figshare
  56. Additional file 6 of Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcription
    Fabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2024 · Figshare
  57. Additional file 1 of Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcription
    Fabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2024 · Figshare
  58. 3D genome conformation and gene expression in fetal pig muscle at late gestation
    María Marti-Marimon · 2018 · theses.fr (ABES)
  59. Fra-1 transcriptional mechanisms in Triple Negative Breast Cancer
    Fabienne Bejjani · 2018
  60. Nouvelle technique de détection simultanée des variant ponctuels et des copy number variants dans l’obésité monogénique
    Mehdi Derhourhi · 2018 · theses.fr (ABES)
  61. SUMOylation and control of gene expression : involvement in Acute Myeloid Leukemia response to induction chemotherapy
    Mathias Boulanger · 2019
  62. Clonally variant non-coding RNA family and its role in Plasmodium falciparum antigenic variation
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  63. Using statistical profiling to decipher hidden chromatin contacts resulting from repeated sequences
    Sébastien Gradit · 2024
  64. Telomere-driven replicative crisis is driven by large-scale changes in genomic architecture
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  65. A divide and conquer strategy for recapitulating whole genome 3D structure using Hi-C data
    J T Park, Meng Wang, Emerson Webb, Victor X. Jin, Shili Lin · 2026 · Biostatistics
  66. How advances in chromosome conformation capture (3C) methods are reshaping our understanding of gene regulation in hematopoiesis
    Hangpeng Li, Nicholas Denny, James Davies · 2026 · Current topics in developmental biology/Current Topics in Developmental Biology
  67. Single-allele nanoscale mapping of regulatory variants
    Joseph C. Hamley, Weijiao Zhang, Daniel Willmott, Lucia Chen, Vassilena Sharlandjieva, Hangpeng Li, James L. T. Dalgleish, Nicholas Denny, Gaurav Agarwal, Lance D. Hentges et al. · 2026 · Nature Genetics
  68. HDAC7 induction combined with standard-of-care chemotherapy provides a therapeutic advantage in t(4;11) infant B-ALL (Dataset)
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  69. Activation of alpha-globin transcription in primary mouse erythroid progenitors
    Robert A. Beagrie, A. Marieke Oudelaar · 2020 · Discovery Research Portal (University of Dundee)