Multiplexed analysis of chromosome conformation at vastly improved sensitivity
Davies, James O J, Telenius, Jelena M, McGowan, Simon J, Roberts, Nigel A, Taylor, Stephen, Higgs, Douglas R, Hughes, Jim R·2016·Nature Methods
Cited by (269)
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- Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-CAntonia Hauth, Rafael Galupa, Nicolas Servant, Laura Villacorta, Kai Hauschulz, Joke Gerarda van Bemmel, Agnese Loda, Édith Heard · 2022 · Journal of Visualized Experiments
- Capture Hi-C: Characterization of chromatin contactsRyan R. Davis, Mel Campbell, Yoshihiro Izumiya, Clifford G. Tepper · 2020 · Elsevier eBooks
- Targeted high-resolution chromosome conformation capture at genome-wide scaleDamien J. Downes, Matthew E. Gosden, Jelena M. Telenius, Stephanie J. Carpenter, Lea Nußbaum, Sara De Ornellas, Martin J. Sergeant, Chris Q. Eijsbouts, Ron Schweßinger, Jon Kerry et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Mapping 3D genome organization at nucleosome-scale with Micro-C and Region Capture Micro-C (RCMC)Miles K. Huseyin, Clarice K. Y. Hong, Masahiro Nagano, James A. Drayton, James M. Jusuf, Jin Yang, Varshini Ramanathan, Viraat Y. Goel, S Y Kim, Anders S. Hansen · 2026 · Nature Protocols
- From Identification to Function: Current Strategies to Prioritise and Follow-Up GWAS ResultsAntonio J. Berlanga‐Taylor · 2018 · Methods in molecular biology
- Model-based analysis of chromatin interactions from dCas9-Based CAPTURE-3C-seqYong Chen, Yunfei Wang, Xin Liu, Jian Xu, Michael Q. Zhang · 2020 · PLoS ONE
- Research progress on the three-dimensional structure of genomeZhengHao Li, Pengchao Li, Xiangyu Yang, Le Zhang, Jun Myoung Yu, Jingtian Zhao · 2019 · Scientia Sinica Vitae
- Enhancers predominantly regulate gene expression in vivo via transcription initiationMartin Larke, Takayuki Nojima, Jelena M. Telenius, Jacqueline A. Sharpe, Jacqueline A. Sloane-Stanley, Sue Butler, Robert A. Beagrie, Damien J. Downes, Ron Schweßinger, A. Marieke Oudelaar et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-CAntonia Hauth, Rafael Galupa, Nicolas Servant, Laura Villacorta, Kai Hauschulz, Joke Gerarda van Bemmel, Agnese Loda, Édith Heard · 2022 · Journal of Visualized Experiments
- Enhancer Arrays Regulating Developmental Genes: Sox2 Enhancers as a ParadigmHisato Kondoh · 2024 · Results and problems in cell differentiation
- Evidence for enhancer activity in intron 1 of TNFRSF1A using CRISPR/Cas9 in human induced pluripotent stem cell-derived macrophagesJulie A. Osgood, Andrew Brown, Katie L. Burnham, Olga Mielczarek, Gabriele Migliorini, Chwen Tay, Ping Zhang, Madeleine H. Palmer, Benjamin Michael Davies, Sally A. Cowley et al. · 2025 · Scientific Reports
- A functional overlap between actively transcribed genes and chromatin insulator elementsLucy Cornell, C. Harrold, S. Holliman, Felice H. Tsang, M. Gosden, L. Hanssen, Rosa J. Stolper, D. Downes, D. Biggs, C. Preece et al. · 2026 · EMBO Journal
- MYB activity drives emergent enhancer activation and enhancer-promoter interactions in acute lymphoblastic leukemiaI‐Jun Lau, Gianna Bloye, Alastair Smith, Joe R. Harman, Joseph C. Hamley, Vassilena Sharlandjieva, Nicholas Denny, Catherine Chahrour, Hangpeng Li, Nicole Jackson et al. · 2026 · Blood
- From Chromosome Conformation Capture to Polymer Physics and BackGuido Tiana, Édith Heard, Luca Giorgetti · 2017 · Elsevier eBooks
- Application of the 3C Method to Study the Developmental Genes in Drosophila LarvaeOleg V. Bylino, Airat N. Ibragimov, Filomena Anna Digilio, Ennio Giordano, Yulii V. Shidlovskii · 2022 · Frontiers in Genetics
- Mechanism of KIT gene regulation by GATA1 lacking the N-terminal domain in Down syndrome–related myeloid disordersRika Kanezaki, Tsutomu Toki, Kiminori Terui, Tomohiko Sato, Akie Kobayashi, Ko Kudo, Takuya Kamio, Shinya Sasaki, Koji Kawaguchi, Kenichiro Watanabe et al. · 2022 · Scientific Reports
- Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcriptionFabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2023 · Cell & Bioscience
- Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cells.Jason Torres, Han Sun, Vibe Nylander, Damien J. Downes, Martijn van de Bunt, Mark I. McCarthy, Jim R. Hughes, Anna L. Gloyn · 2023 · PubMed Central
- Best practices for the ATAC-seq assay and its data analysisHaibo Liu, Rui Li, Kai Hu, Jianhong Ou, Magnolia L. Pak, Michael R. Green, Lihua Julie Zhu · 2024 · Elsevier eBooks
- CaptureProbe: a java tool for designing probes for capture Hi-C applicationsMa Yun-Fei, Adeniyi C. Adeola, Sun Yan-bo, Hai‐Bing Xie, Zhang Ya-ping · 2020 · 动物学研究
- A base-pair view of interactions between genes and their enhancersAnne Onrust-van Schoonhoven, Ralph Stadhouders · 2021 · Nature
- MC4C: Locus-Specific Enhancer Hubs And Architectural Loop Collisions Uncovered From Single Allele DNA TopologiesAmin Allahyar · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Myeloid leukemia vulnerabilities at CTCF-enriched long noncoding RNA lociMichelle Shu Wen Ng, Lonneke Verboon, Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Dorit Borchert, K Schuschel, Enikő Regényi, Dirk Reinhardt, Marie‐Laure Yaspo et al. · 2021 · Research Square
- Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cellsJason Torres, Han Sun, Vibe Nylander, Damien J. Downes, Martijn van de Bunt, Mark I. McCarthy, Jim R. Hughes, Anna L. Gloyn · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- RNA-mediated SOX2 temporal dynamics govern dual chromatin-engagement modes at NanogBitong Li, Yew Yan Wong, Yoshiaki Kobayashi, Neftali Flores Rodriguez, Tara‐Lynne Davidson, Matthew S. Graus, Valeriia Smialkovska, Shikha Pachauri, Susav Pradhan, Xiaohui Gao et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Characterizing trajectory-like chromatin architectures with Fun2Zhengrong Zhangding, Xuhao Liu, Jiazhi Hu · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Analysis of multi-way chromatin interactions at sub-nucleosome resolution identifies synergistic nano-scale interactions within super-enhancersShyam Ramasamy, Yi Zhu, Magdalena A. Karpińska, Ilya M. Flyamer, Johannes Söding, A. Marieke Oudelaar · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Epigenetic Rewiring of Enhancer–Promoter Interactions in Cancer: Mechanisms and Therapeutic ImplicationsChoppavarapu, Lavanya, Nosirov, Bakhtiyor, Kahn, Michael, Jin, Victor X. · 2026 · Cancers
- Unraveling nuclear architectureNicole Rusk · 2015 · Nature Methods
- The impact of endogenous retroviruses on nuclear organization and gene expressionRamya Raviram, Pedro P. Rocha, Vincent Mingyi Luo, Emily Swanzey, Emily R. Miraldi, Edward B. Chuong, Cédric Feschotte, Richard Bonneau, Jane A. Skok · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Chromatin 3D – will it make understanding of cancer transformation finally possible?Grażyna Drabik, Jolanta Kaszuba-Zwoińska, Zdzisław Wiśniowski, Leszek Konieczny, Irena Roterman · 2018 · Bio-Algorithms and Med-Systems
- Commentary: Nuclear dynamics of the Set1C subunit Spp1 prepares meiotic recombination sites for break formationCsaba Fillér, Lilla Hornyák, Jason Roszik · 2018 · Frontiers in Genetics
- Chromatin topology defines cell identity and phenotypic transition in human cancer and fungal pathogenYao Chen · 2020
- Myeloid leukemia vulnerabilities at CTCF-enriched long noncoding RNA lociMichelle Shu Wen Ng, Lonneke Verboon, Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Dorit Borchert, K Schuschel, Enikő Regényi, Dirk Reinhardt, Marie‐Laure Yaspo et al. · 2021 · Research Square
- Correction to: Epigenetic and Transcriptional Networks Underlying Atrial Fibrillation2020 · Circulation Research
- Bioinformatics analysis of multi-omics data elucidates the primary function of Oct4 in gene regulation and pluripotency maintenanceLe Xiong · 2022
- Faculty Opinions recommendation of Tissue-specific CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo.Amy L. Kenter · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Reviewer #2 (Public Review): A genome-wide nucleosome-resolution map of promoter-centered interactions in human cells corroborates the enhancer-promoter looping modelArkadiy K. Golov, Alexey A. Gavrilov, Noam Kaplan · 2023 · eLife
- eLife Assessment: A genome-wide nucleosome-resolution map of promoter-centered interactions in human cells corroborates the enhancer-promoter looping modelJian Xu · 2023 · eLife
- A genome-wide nucleosome-resolution map of promoter-centered interactions in human cells corroborates the enhancer-promoter looping modelArkadiy K. Golov, Alexey A. Gavrilov, Noam Kaplan, Sergey V. Razin · 2024 · eLife
- Using paired-end read orientations to assess technical biases in capture Hi-CPeter Hansen, Hannah Blau, Jochen Hecht, Guy Karlebach, Alexander Krannich, Robin Steinhaus, Matthias Truß, Peter N. Robinson · 2024 · NAR Genomics and Bioinformatics
- Anti-Phase Clustering of Regulatory Factors Shapes Gene Transcription BurstBitong Li, Yew Yan Wong, Neftali Flores Rodriguez, Tara Davidson, Matthew S. Graus, Valeriia Smialkovska, Hiroaki Ohishi, Angelika Feldmann, Hiroshi Ochiai, Mathias François · 2025 · SSRN Electronic Journal
- Sustained MYB activity drives emergent enhancer activation and precise enhancer-promoter interactionsI‐Jun Lau, Joe R. Harman, Alastair Smith, Nicholas Denny, Nicole Jackson, Joseph C. Hamley, Paresh Vyas, James O. J. Davies, Jim R. Hughes, Nicholas T. Crump et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Additional file 2 of Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcriptionFabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2024 · Figshare
- Additional file 5 of Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcriptionFabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2024 · Figshare
- Additional file 4 of Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcriptionFabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2024 · Figshare
- Additional file 3 of Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcriptionFabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2024 · Figshare
- Additional file 7 of Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcriptionFabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2024 · Figshare
- Additional file 6 of Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcriptionFabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2024 · Figshare
- Additional file 1 of Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcriptionFabienne Bejjani, Emilie Evanno, Samantha Mahfoud, Claire Tolza, Kazem Zibara, Marc Piechaczyk, Isabelle Jariel‐Encontre · 2024 · Figshare
- 3D genome conformation and gene expression in fetal pig muscle at late gestationMaría Marti-Marimon · 2018 · theses.fr (ABES)
- Fra-1 transcriptional mechanisms in Triple Negative Breast CancerFabienne Bejjani · 2018
- Nouvelle technique de détection simultanée des variant ponctuels et des copy number variants dans l’obésité monogéniqueMehdi Derhourhi · 2018 · theses.fr (ABES)
- SUMOylation and control of gene expression : involvement in Acute Myeloid Leukemia response to induction chemotherapyMathias Boulanger · 2019
- Clonally variant non-coding RNA family and its role in Plasmodium falciparum antigenic variationAnna Barcons-Simon · 2019 · theses.fr (ABES)
- Using statistical profiling to decipher hidden chromatin contacts resulting from repeated sequencesSébastien Gradit · 2024
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- A divide and conquer strategy for recapitulating whole genome 3D structure using Hi-C dataJ T Park, Meng Wang, Emerson Webb, Victor X. Jin, Shili Lin · 2026 · Biostatistics
- How advances in chromosome conformation capture (3C) methods are reshaping our understanding of gene regulation in hematopoiesisHangpeng Li, Nicholas Denny, James Davies · 2026 · Current topics in developmental biology/Current Topics in Developmental Biology
- Single-allele nanoscale mapping of regulatory variantsJoseph C. Hamley, Weijiao Zhang, Daniel Willmott, Lucia Chen, Vassilena Sharlandjieva, Hangpeng Li, James L. T. Dalgleish, Nicholas Denny, Gaurav Agarwal, Lance D. Hentges et al. · 2026 · Nature Genetics
- HDAC7 induction combined with standard-of-care chemotherapy provides a therapeutic advantage in t(4;11) infant B-ALL (Dataset)Oriol de Barrios, Juan Ramón Tejedor, Maribel Parra · 2024 · Zenodo (CERN European Organization for Nuclear Research)
- Activation of alpha-globin transcription in primary mouse erythroid progenitorsRobert A. Beagrie, A. Marieke Oudelaar · 2020 · Discovery Research Portal (University of Dundee)