Epigenetic Rewiring of Enhancer–Promoter Interactions in Cancer: Mechanisms and Therapeutic Implications

Hallmarks of Cancer: New Dimensions

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Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

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A unique chromatin signature uncovers early developmental enhancers in humans

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Differential oestrogen receptor binding is associated with clinical outcome in breast cancer

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Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions

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Formation of chromosomal domains by loop extrusion

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Mediator and cohesin connect gene expression and chromatin architecture

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Cohesin Loss Eliminates All Loop Domains

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Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers

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Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

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A Phase Separation Model for Transcriptional Control

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Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization

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Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

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DNA-binding factors shape the mouse methylome at distal regulatory regions

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Epigenetic Determinants of CancerPreprint

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Epigenetic plasticity and the hallmarks of cancer

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Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes

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The chromatin accessibility landscape of primary human cancers

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Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

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Transcriptional Addiction in Cancer

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Organizational principles of 3D genome architecture

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Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity

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Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

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Ever-Changing Landscapes: Transcriptional Enhancers in Development and Evolution

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The 3D Genome as Moderator of Chromosomal Communication

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Epigenetic modulators, modifiers and mediators in cancer aetiology and progression

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Ultrastructural Details of Mammalian Chromosome Architecture

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Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer

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