Functional organization of the transcriptome in human brain

Oldham, Michael C, Konopka, Genevieve, Iwamoto, Kazuya, Langfelder, Peter, Kato, Tadafumi, Horvath, Steve, Geschwind, Daniel H·2008·Nature Neuroscience

DOI 10.1038/nn.2207

Cited by (766)

Items 101–200 of 766

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Meixiang Huang, Erica S. Modeste, Eric B. Dammer, Paola Merino, Georgia Taylor, Duc Minh Duong, Qiudong Deng, Christopher J. Holler, Marla Gearing, Dennis W. Dickson et al. · 2020 · Acta Neuropathologica Communications
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Megan K. Mulligan, Justin S. Rhodes, John C. Crabbe, Roy Dayne Mayfield, Robert Adron Harris, Igor Ponomarev · 2011 · Alcoholism Clinical and Experimental Research
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Melissa A. C. Ingram, Emily A.L. Wozniak, Lisa A. Duvick, Rendong Yang, Paul E. Bergmann, Robert Carson, Brennon L. O’Callaghan, Huda Yahya Zoghbi, Christine M. Henzler, Harry T. Orr · 2016 · Neuron
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Liu, Siling, Wang, Zhengbo, Chen, Dong, Zhang, Bowen, Tian, Ren-Rong, Wu, Jing, Zhang, Ying, Xu, Kaiyu, Yang, Liu-Meng, Cheng, Chao et al. · 2017 · Genome Research
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Ebru Ercan-Herbst, Juliette M. Han, Alessia Di Nardo, Kellen Diamond Winden, Min‐Joon Han, Leonie Hoyo, Afshin Saffari, Andrew Leask, Daniel H. Geschwind, Mustafa Şahin · 2017 · The Journal of Experimental Medicine
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Roussos, Panos, Katsel, Pavel, Davis, Kenneth L., Siever, Larry J., Haroutunian, Vahram · 2012 · Archives of General Psychiatry
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Claire Morandin, Mandy M. Y. Tin, Sílvia Abril, Crisanto Gómez, Luigi Pontieri, Morten Schiøtt, Liselotte Sundström, Kazuki Tsuji, Jes Søe Pedersen, Heikki Helanterä et al. · 2016 · Genome biology
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Chuan Xu, Qian Li, Olga Efimova, Liu He, Shoji Tatsumoto, Vita V. Stepanova, Takao Oishi, Toshifumi Udono, Katsushi Yamaguchi, Shuji Shigenobu et al. · 2018 · Genome Research
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Yingyu Sun, Wei Zhang, Dongfeng Chen, Yu-Hong Lv, Junxiong Zheng, Henrik Lilljebjörn, Ran Liang, Zhaoshi Bao, Charlotte Soneson, Hans Olov Sjögren et al. · 2014 · Proceedings of the National Academy of Sciences
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Kapoor, Manav, Wang, Jen-Chyong, Farris, Sean P., Liu, Yunlong, McClintick, Jeanette, Gupta, Ishaan, Meyers, Jacquelyn L., Bertelsen, Sarah, Chao, Michael, Nurnberger, John et al. · 2019 · Translational Psychiatry
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Yuji Jiang, Bo Sun, Huixin Li, Manqiang Liu, Lijun Chen, Zhou Sai · 2015 · Soil Biology and Biochemistry
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Lein, Ed S., Belgard, T. Grant, Hawrylycz, Michael, Molnár, Zoltán · 2017 · Annual Review of Neuroscience
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Rishika Kundra, Prajwal Ciryam, Richard I. Morimoto, Christopher Martin Dobson, Michele Vendruscolo · 2017 · Proceedings of the National Academy of Sciences
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Meeta Mistry, Jesse A Gillis, Paul Pavlidis · 2012 · Molecular Psychiatry
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Patir, Anirudh, Shih, Barbara, McColl, Barry W., Freeman, Tom C. · 2019 · Glia
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Ji Zhang, Meige Guan, Qianliang Wang, Jiajun Zhang, Tianshou Zhou, Xiaoqiang Sun · 2019 · Briefings in Bioinformatics
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Ileena Mitra, Kathryn M. Tsang, Christine Ladd‐Acosta, Lisa Croen, Kimberly A. Aldinger, Robert L. Hendren, Michela Traglia, Alinoë Lavillaureix, Noah Zaitlen, Michael C. Oldham et al. · 2016 · PLoS Genetics
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William G. Pembroke, Christopher Hartl, Daniel H. Geschwind · 2021 · Genome biology
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Chi H. E. Ma, Gary J. Brenner, Takao Omura, Omar Abdel Samad, Michael Costigan, Perrine Inquimbert, Vera Niederkofler, Rishard Salie, Chia Chi Sun, Herbert Yih-Fuu Lin et al. · 2011 · Journal of Neuroscience
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Beatriz Morte, Diego Díez, Eva Ausó, Mónica M. Belinchón, Pilar Gil-Ibáñez, Carmen Grijota-Martínez, Daniela Navarro, Gabriella Morreale de Escobar, Pere J. Berbel, Juan Bernal · 2010 · Endocrinology
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Nikos Kyritsis, Abel Torres Espin, Patrick G. Schupp, John Russell Huie, Austin Chou, Xuan Duong Fernandez, Leigh H. Thomas, Rachel E. Tsolinas, Debra D. Hemmerle, Lisa U. Pascual et al. · 2020 · The Journal of Experimental Medicine
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Nicola Johnstone, Chiara Milesi, Olivia Burn, Bartholomeus van den Bogert, Arjen Nauta, Kathryn H. Hart, Paul T. Sowden, Philip W. J. Burnet, Kathrin Cohen Kadosh · 2021 · Scientific Reports
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Geneviève Konopka, Eric Wexler, E Rosen, Zohar Mukamel, Gregory E. Osborn, L Chen, Daning Lu, Fuying Gao, Kun Gao, Jennifer K. Lowe et al. · 2011 · Molecular Psychiatry
Identification of candidate miRNA biomarkers for pancreatic ductal adenocarcinoma by weighted gene co-expression network analysis
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