Whither proBDNF?
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Both mature BDNF and pro-BDNF can be secreted and bind to the low affinity p75 neurotrophin receptor (p75NTR), which causes activation of the apoptosis cascade.
“Both mature BDNF and pro-BDNF can be secreted and bind to the low affinity p75 neurotrophin receptor (p75NTR), which causes activation of the apoptosis cascade [6, 7].”
From Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation (2019) · cites this paper as [6]
Cites
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Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation
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XIONG, J., ZHOU, L., LIM, Y., YANG, M., ZHU, Y.-H., LI, Z.-W., FU, D.-L., & ZHOU, X.-F. (2015) · Oncology Letters · doi:10.3892/ol.2015.3181 · Cited by 38 · see citing works
- Authors
- Barker, P. A.
- Affiliations
- McGill University (CA)
- Corresponding author
- Barker, Philip A
- ORCID
- Barker, Philip A
- Venue
- Nature Neuroscience
- Published
- 2009-02
- Volume
- 12
- Issue
- 2
- Pages
- 105-106
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- OpenAlex
- W4240168071
- Cited by
- 110
- References
- 15
- Citations by year
- 2026: 2 · 2025: 7 · 2024: 4 · 2023: 4 · 2022: 5 · 2021: 9 · 2020: 5 · 2019: 4 · 2018: 2 · 2017: 5 · 2016: 15 · 2015: 11 · 2014: 13 · 2013: 8 · 2012: 3
- FWCI
- 2.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- proBDNF, brain-derived neurotrophic factor, synaptic plasticity, neurosecretion, central nervous system neurons
- MeSH terms
- Animals, Neuronal Plasticity, Neurons, Protein Precursors, Brain-Derived Neurotrophic Factor
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