The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.
The Impact of Gabapentin Administration on Brain GABA and Glutamate Concentrations: A 7T 1H-MRS Study
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Using a fitting method validated by Cai et al (2012), metabolite peaks from water-suppressed spectrum were fitted as Lorentzian functions with nonlinear least squares fitting using lsqcurvefit in MATLAB.”
From Lisdexamfetamine Effects on Executive Activation and Neurochemistry in Menopausal Women with Executive Function Difficulties (2017) · cites this paper as Cai et al (2012)
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Estimation of metabolite concentrations from localized in vivo proton NMR spectra
Provencher, S. W. (1993) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910300604 · Cited by 3,659
The Novel Anticonvulsant Drug, Gabapentin (Neurontin), Binds to the α2δ Subunit of a Calcium Channel
Gee, N. S., Brown, J. P., Dissanayake, V. U. K., Offord, J., Thurlow, R., & Woodruff, G. N. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.10.5768 · Cited by 1,181
In vivo1H NMR spectroscopy of rat brain at 1 ms echo time
Tk�?, I., uk, Z. S., Choi, I., & Rolf Gruetter, A. (1999) · Magnetic Resonance in Medicine · doi:10.1002/(sici)1522-2594(199904)41:4<649::aid-mrm2>3.0.co;2-g · Cited by 1,005
Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders
Sanacora, G., Zarate, C. A., Krystal, J. H., & Manji, H. K. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2462 · Cited by 894
Hasler, G., van der Veen, J. W., Tumonis, T., Meyers, N., Shen, J., & Drevets, W. C. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.2.193 · Cited by 846
Subtype-Specific Alterations of γ-Aminobutyric Acid and Glutamatein Patients With Major Depression
Sanacora, G., Gueorguieva, R., Epperson, C. N., Wu, Y.-T., Appel, M., Rothman, D. L., Krystal, J. H., & Mason, G. F. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.7.705 · Cited by 796
Self-citationCipriani, A., Barbui, C., Salanti, G., Rendell, J., Brown, R., Stockton, S., Purgato, M., Spineli, L. M., Goodwin, G. M., & Geddes, J. R. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60873-8 · Cited by 631
Sanacora, G., Mason, G. F., Rothman, D. L., Behar, K. L., Hyder, F., Petroff, O. A. C., Berman, R. M., Charney, D. S., & Krystal, J. H. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.11.1043 · Cited by 627 · cited 2×
“…difference in GABA concentrations both within day and between day, we are capable of detecting smaller differences between groups (Epperson et al, 2002, 2006; Sanacora et al, 1999) or with pharmacologic and nonpharmacologic interventions than those previously observed (Sanacora et al, 2002, 2008).”
BackgroundResultAuer, D. P., Pütz, B., Kraft, E., Lipinski, B., Schill, J., & Holsboer, F. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00159-6 · Cited by 564
Localized 1H NMR measurements of gamma-aminobutyric acid in human brain in vivo.
Rothman, D. L., Petroff, O. A. C., Behar, K. L., & Mattson, R. H. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.12.5662 · Cited by 510
Sanacora, G., Mason, G. F., Rothman, D. L., & Krystal, J. H. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.4.663 · Cited by 494
Glutamate in Schizophrenia: A Focused Review and Meta-Analysis of 1H-MRS Studies
Marsman, A., van den Heuvel, M. P., Klomp, D. W. J., Kahn, R. S., Luijten, P. R., & Hulshoff Pol, H. E. (2013) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr069 · Cited by 457
Epperson, C. N., Haga, K., Mason, G. F., Sellers, E., Gueorguieva, R., Zhang, W., Weiss, E., Rothman, D. L., & Krystal, J. H. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.9.851 · Cited by 399
Self-citationMagnetic Resonance Spectroscopy
Gujar, S. K., Maheshwari, S., Bj??rkman-Burtscher, I., & Sundgren, P. C. (2005) · Journal of Neuro-Ophthalmology · doi:10.1097/01.wno.0000177307.21081.81 · Cited by 380
Efficacy of Gabapentin in Migraine Prophylaxis
Mathew, N. T., Rapoport, A., Saper, J., Magnus, L., Klapper, J., Ramadan, N., Stacey, B., & Tepper, S. (2001) · Headache: The Journal of Head and Face Pain · doi:10.1046/j.1526-4610.2001.111006119.x · Cited by 343
Caffeine Induces Dopamine and Glutamate Release in the Shell of the Nucleus Accumbens
Solinas, M., Ferré, S., You, Z.-B., Karcz-Kubicha, M., Popoli, P., & Goldberg, S. R. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-15-06321.2002 · Cited by 338
Gabapentin: A Review of its Pharmacological Properties and Clinical Potential in Epilepsy
Goa, K. L., & Sorkin, E. M. (1993) · Drugs · doi:10.2165/00003495-199346030-00007 · Cited by 323
Mao, X. (2012) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.1519 · Cited by 296
The effect of gabapentin on brain gamma‐aminobutyric acid in patients with epilepsy
Petroff, O. A. C., Rothman, D. L., Behar, K. L., Lamoureux, D., & Mattson, R. H. (1996) · Annals of Neurology · doi:10.1002/ana.410390114 · Cited by 285
Price, R. B., Shungu, D. C., Mao, X., Nestadt, P., Kelly, C., Collins, K. A., Murrough, J. W., Charney, D. S., & Mathew, S. J. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.10.025 · Cited by 270
Goddard, A. W., Mason, G. F., Almai, A., Rothman, D. L., Behar, K. L., Petroff, O. A. C., Charney, D. S., & Krystal, J. H. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.6.556 · Cited by 255
In vivo detection of GABA and glutamate with MEGA‐PRESS: Reproducibility and gender effects
Tuura, R., Michels, L., Edden, R. A. E., Murdoch, J. B., & Martin, E. (2011) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.22520 · Cited by 219
Homonuclear 1H double-resonance difference spectroscopy of the rat brain in vivo.
Rothman, D. L., Behar, K. L., Hetherington, H. P., & Shulman, R. G. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.20.6330 · Cited by 209
Neuronal Glutamate Uptake Contributes to GABA Synthesis and Inhibitory Synaptic Strength
Mathews, G. C., & Diamond, J. S. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-06-02040.2003 · Cited by 204
Gabapentin increases aminooxyacetic acid-induced GABA accumulation in several regions of rat brain
Löscher, W., Hönack, D., & Taylor, C. P. (1991) · Neuroscience Letters · doi:10.1016/0304-3940(91)90249-s · Cited by 196
Modulation of cerebral GABA by topiramate, lamotrigine, and gabapentin in healthy adults
Kuzniecky, R., Ho, S., Pan, J. W., Martin, R. C., Gilliam, F. G., Faught, E., & Hetherington, H. P. (2002) · Neurology · doi:10.1212/wnl.58.3.368 · Cited by 174
Fink, K., Meder, W. P., Dooley, D. J., & Göthert, M. (2000) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0703380 · Cited by 169
Preliminary evidence of reduced occipital GABA concentrations in puerperal women: a 1H-MRS study
Epperson, C. N., Gueorguieva, R. V., Czarkowski, K. A., Stiklus, S. M., Sellers, E. M., Krystal, J. H., Rothman, D. L., & Mason, G. F. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0313-7 · Cited by 149
Self-citationA new general-purpose fully automatic baseline-correction procedure for 1D and 2D NMR data
Cobas, J. C., Bernstein, M. A., Martín‐Pastor, M., & Tahoces, P. G. (2006) · Journal of Magnetic Resonance · doi:10.1016/j.jmr.2006.07.013 · Cited by 148
Effects of anticonvulsant drug gabapentin on the enzymes in metabolic pathways of glutamate and GABA
Goldlust, A., Su, T., Welty, D. F., Taylor, C. P., & Oxender, D. L. (1995) · Epilepsy Research · doi:10.1016/0920-1211(95)00028-9 · Cited by 142
Glutamate Uptake Triggers Transporter-Mediated GABA Release from Astrocytes
Héja, L., Barabás, P., Nyitrai, G., Kékesi, K. A., Lasztóczi, B., Tőke, O., Tárkányi, G., Madsen, K. K., Schousboe, A., Dobolyi, Á., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007153 · Cited by 137
Gabapentin vs. Amitriptyline in Painful Diabetic Neuropathy
Dallocchio, C., Buffa, C., Mazzarello, P., & Chiroli, S. (2000) · Journal of Pain and Symptom Management · doi:10.1016/s0885-3924(00)00181-0 · Cited by 131
Direct in vivo measurement of human cerebral GABA concentration using MEGA‐editing at 7 Tesla
Terpstra, M., Uǧurbil, K., & Rolf Gruetter, A. (2002) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10146 · Cited by 131
Licata, S. C., & Renshaw, P. F. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05143.x · Cited by 121
Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy
Petroff, O. A. C., Hyder, F., Mattson, R. H., & Rothman, D. L. (1999) · Neurology · doi:10.1212/wnl.52.3.473 · Cited by 119
Effects of Gabapentin on Brain GABA, Homocarnosine, and Pyrrolidinone in Epilepsy Patients
Petroff, O. A. C., Hyder, F., Rothman, D. L., et al. (2000) · Epilepsia · doi:10.1111/j.1528-1157.2000.tb00227.x · Cited by 110
Petroff, O. A. C., Rothman, D. L., Behar, K. L., & Mattson, R. H. (1995) · Epilepsia · doi:10.1111/j.1528-1157.1995.tb00486.x · Cited by 100
3-Alkyl GABA and 3-alkylglutamic acid analogues: two new classes of anticonvulsant agents
Taylor, C. P., Vartanian, M. G., Andruszkiewicz, R., et al. (1992) · Epilepsy Research · doi:10.1016/0920-1211(92)90044-t · Cited by 96
Silverman, R. B., Andruszkiewicz, R., Nanavati, S. M., Taylor, C. P., & Vartanian, M. G. (1991) · Journal of Medicinal Chemistry · doi:10.1021/jm00111a053 · Cited by 92
Brain metabolism differs in Alzheimer's disease and Parkinson's disease dementia
Griffith, H. R., den Hollander, J. A., Okonkwo, O. C., O’Brien, T. D., Watts, R. L., & Marson, D. C. (2008) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2008.04.008 · Cited by 89
Detre, J. A., Wang, Z., Bogdan, A. R., Gusnard, D. A., Bay, C. A., Bingham, P. M., & Zimmerman, R. A. (1991) · Annals of Neurology · doi:10.1002/ana.410290219 · Cited by 86
Petroff, O. A. C., Behar, K. L., Mattson, R. H., & Rothman, D. L. (1996) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1996.67062399.x · Cited by 85
Gomez, R., Behar, K. L., Watzl, J., WEINZIMER, S. A., Gulanski, B., Sanacora, G., Koretski, J. A., Guidone, E., Jiang, L., Petrakis, I. L., et al. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.06.026 · Cited by 85
Kassem, M. N. E., & Bartha, R. (2003) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10443 · Cited by 84
Gabapentin and vigabatrin increase GABA in the human neocortical slice
Errante, L. D., Williamson, A., Spencer, D. D., & Petroff, O. A. C. (2002) · Epilepsy Research · doi:10.1016/s0920-1211(02)00034-7 · Cited by 78
Punwani, S., Ordidge, R. J., Cooper, C. E., Amess, P., & Clemence, M. (1998) · NMR in Biomedicine · doi:10.1002/(sici)1099-1492(199810)11:6<266::aid-nbm530>3.0.co;2-j · Cited by 74
Petroff, O. A. C., Rothman, D. L., Behar, K. L., & Mattson, R. H. (1996) · Neurology · doi:10.1212/wnl.46.5.1459 · Cited by 73
Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes
Kammerer, M. M., Rassner, M. P., Freiman, T. M., & Feuerstein, T. J. (2011) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-011-0636-8 · Cited by 66
Mader, I., Seeger, U., Karitzky, J., Erb, M., Schick, F., & Klose, U. (2002) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.10190 · Cited by 64
Edelsberg, J., Lord, C., & Oster, G. (2011) · Annals of Pharmacotherapy · doi:10.1345/aph.1p777 · Cited by 63
Hasler, G., van der Veen, J. W., Geraci, M., Shen, J., Pine, D., & Drevets, W. C. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.06.023 · Cited by 58
Measurement of glycine in the human brain in vivo by 1H‐MRS at 3 T: application in brain tumors
Choi, C., Ganji, S., DeBerardinis, R. J., Dimitrov, I. E., Pascual, J. M., Bachoo, R. M., Mickey, B., Malloy, C. R., & Maher, E. A. (2011) · Magnetic Resonance in Medicine · doi:10.1002/mrm.22857 · Cited by 55
Benedetti, F., Calabrese, G., Bernasconi, A., Cadioli, M., Colombo, C., Dallaspezia, S., Falini, A., Radaelli, D., Scotti, G., & Smeraldi, E. (2009) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2008.08.004 · Cited by 53
Rapchuk, I. L., O’Connell, L., Liessmann, C. D., Cornelissen, H., & Fraser, J. F. (2010) · Anaesthesia and Intensive Care · doi:10.1177/0310057x1003800306 · Cited by 52
Neurochemical actions of gabapentin in mouse brain
Leach, J. P., Sills, G. J., Butler, E., Forrest, G., Thompson, G. G., & Brodie, M. J. (1997) · Epilepsy Research · doi:10.1016/s0920-1211(97)01034-6 · Cited by 49
Gabapentin: An update of its pharmacological properties and therapeutic use in epilepsy.
Honarmand, A., Safavi, M., & Zare, M. (2011) · PubMed · Cited by 33
Activation of two types of brain glutamate dehydrogenase isoproteins by gabapentin
Cho, S., Cho, E. H., & Choi, S. Y. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)00335-4 · Cited by 22
Brain GABA editing by localized in vivo1H magnetic resonance spectroscopy
Biélicki, G., Chassain, C., Renou, J., Farges, M. ‐., Vasson, M., Eschalier, A., & Durif, F. (2004) · NMR in Biomedicine · doi:10.1002/nbm.863 · Cited by 20
Quantitative maps of GABAergic and glutamatergic neuronal systems in the human brain
Sutoo, D., Akiyama, K., & Yabe, K. (2000) · Human Brain Mapping · Cited by 17
Brain Homocarnosine and Seizure Control of Patients Taking Gabapentin or Topiramate
Petroff, O. A. C., Hyder, F., Rothman, D. L., & Mattson, R. H. (2006) · Epilepsia · doi:10.1111/j.1528-1167.2006.00457.x · Cited by 15
Research works printed but not linked: 1
- First MB, Spitzer RL, Gibbon M, Williams JBW . Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Non-Patient Edition. (SCID-I/NP). Biometrics Research, New York State Psychiatric Institute: New York. November 2002.
Cited by
Anton, R. F., Latham, P., Voronin, K., Book, S., Hoffman, M., Prisciandaro, J., & Bristol, E. (2020) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2020.0249 · Cited by 186
Reducing Gabaergic Inhibition Restores Cognitive Functions in a Mouse Model of Down Syndrome
Potier, M.-C., Braudeau, J., Dauphinot, L., & Delatour, B. (2014) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/18715273113126660185 · Cited by 34
Shanmugan, S., Loughead, J., Nanga, R. P. R., Elliott, M., Hariharan, H., Appleby, D., Kim, D., Ruparel, K., Reddy, R., Brown, T. E., et al. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2016.162 · Cited by 33
Self-citationTranscriptional and cellular signatures of cortical morphometric remodelling in chronic pain
Martins, D., Dipasquale, O., Veronese, M., Turkheimer, F., Loggia, M. L., McMahon, S., Howard, M. A., & Williams, S. C. R. (2022) · Pain · doi:10.1097/j.pain.0000000000002480 · Cited by 27
Metadata
- Authors
- Cai, K., Nanga, R. P., Lamprou, L., Schinstine, C., Elliott, M., Hariharan, H., Reddy, R., & Epperson, C. N.
- Venue
- Neuropsychopharmacology
- Published
- 2012-08-08
- Volume
- 37
- Issue
- 13
- Pages
- 2764-2771
- ISSN
- 0893-133X
- 1740-634X
- Cited by
- 128
- References
- 60
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.