The circadian clock: pacemaker and tumour suppressor

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Items 301–400 of 673

1. The reciprocal interplay between TNFα and the circadian clock impacts on cell proliferation and migration in Hodgkin lymphoma cells
   Mónica Abreu, Alireza Basti, Николай Генов, Gianluigi Mazzoccoli, Angela Relógio · 2018 · Scientific Reports
2. The Neurospora crassa OS MAPK pathway-activated transcription factor ASL-1 contributes to circadian rhythms in pathway responsive clock-controlled genes
   Teresa M. Lamb, Katelyn E. Finch, Deborah Bell‐Pedersen · 2012 · Fungal Genetics and Biology
3. Cancer and Rhythm
   M. Moser, Karin Schaumberger, Eva S. Schernhammer, Richard G. Stevens · 2006 · Cancer Causes & Control
4. Expression of circadian clock genes in human colorectal adenoma and carcinoma
   Tomoyuki Momma, Hirokazu Okayama, Masaru Saitou, Hidekazu Sugeno, Nobuhiro Yoshimoto, Yuji Takebayashi, Shinji Ohki, Seiichi Takenoshita · 2017 · Oncology Letters
5. The circadian gene CRY2 is associated with breast cancer aggressiveness possibly via epigenomic modifications
   Yingying Mao, Alan Fu, Aaron E. Hoffman, Daniel Jacobs, Mingjuan Jin, Kun Chen, Yong Lian Zhu · 2015 · Tumor Biology
6. FBXW7 and the Hallmarks of Cancer: Underlying Mechanisms and Prospective Strategies
   Wenyue Shen, Quanwei Zhou, Chenxi Peng, Jiaheng Li, Qizhi Yuan, Hecheng Zhu, Mingwen Zhao, Xingjun Jiang, Weidong Liu, Caiping Ren · 2022 · Frontiers in Oncology
7. Modelling Physiological and Pharmacological Control on Cell Proliferation to Optimise Cancer Treatments
   Jean Clairambault · 2009 · Mathematical Modelling of Natural Phenomena
8. Dysregulation, functional implications, and prognostic ability of the circadian clock across cancers
   Zekun Liu, Kai Yu, Jian Zheng, Huan Lin, Qi Zhao, Xiao-Long Zhang, Weiyi Feng, Liyu Wang, Jianjun Xu, Dawei Xie et al. · 2019 · Cancer Medicine
9. PFKFB3 Control of Cancer Growth by Responding to Circadian Clock Outputs
   Lili Chen, Jiajia Zhao, Qingming Tang, Honggui Li, Chenguang Zhang, Ran Yu, Yan Zhao, Yuqing Huo, Chaodong Wu · 2016 · Scientific Reports
10. LIVER CIRCADIAN CLOCK, A PHARMACOLOGIC TARGET OF CYCLIN-DEPENDENT KINASE INHIBITOR SELICICLIB
    Ida Iurisci, Elisabeth Filipski, Hatem Sallam, Francis Harper, Catherine Guettier, Irène Maire, Moustapha Hassan, Stefano Iacobelli, Françis Lévi · 2009 · Chronobiology International
11. Per2 participates in AKT-mediated drug resistance in A549/DDP lung adenocarcinoma cells
    Bo Chen, Yaoxi Tan, Yan Liang, Yan Li, Lei Chen, Shuangshuang Wu, Wei Xu, Yan Wang, Weihong Zhao, Jianqing Wu · 2016 · Oncology Letters
12. The potential remedy of melatonin on osteoarthritis
    Ko-Hsiu Lu, P. W. Lu, Eric Wun-Hao Lu, Chih-Hsin Tang, Shih-Chi Su, Chiao-Wen Lin, Shun-Fa Yang · 2021 · Journal of Pineal Research
13. Correlation between Circadian Gene Variants and Serum Levels of Sex Steroids and Insulin-like Growth Factor-I
    Lisa W. Chu, Yong Lian Zhu, Kai Yu, Tongzhang Zheng, Anand P. Chokkalingam, Frank Z. Stanczyk, Yu‐Tang Gao, Ann W. Hsing · 2008 · Cancer Epidemiology Biomarkers & Prevention
14. A Working Threshold for Acute Nocturnal Melatonin Suppression from “White” Light Sources used in Architectural Applications
    Mariana G. Figueiro · 2013 · Journal of Carcinogenesis & Mutagenesis
15. P-glycoprotein Function in the Rodent Brain Displays a Daily Rhythm, a Quantitative In Vivo PET Study
    Heli Savolainen, Peter Meerlo, Philip H. Elsinga, Albert D. Windhorst, Rudi Dierckx, Nicola Antonio Colabufo, Aren van Waarde, Gert Luurtsema · 2016 · The AAPS Journal
16. Revealing dynamic regulations and the related key proteins of myeloma-initiating cells by integrating experimental data into a systems biological model
    Le Zhang, Guangdi Liu, Meijing Kong, Jianrong Li, Dan Wu, Xiaobo Zhou, Chuanwei Yang, Lei Xia, Zhenzhou Yang, Luonan Chen · 2019 · Bioinformatics
17. A metabolomic study of adipose tissue in mice with a disruption of the circadian system
    Castro, C, Briggs, W, Paschos, G K, FitzGerald, G A, Griffin, J L · 2015 · Molecular BioSystems
18. Circadian Rhythms in Gastroenterology: The Biological Clock’s Impact on Gut Health
    Faraz Bishehsari, Zoë Post, Garth R. Swanson, Ali Keshavarzian · 2025 · Gastroenterology
19. Sex and Dosing-Time Dependencies in Irinotecan-Induced Circadian Disruption
    Constance Ahowesso, Xiaomei Li, Sinisa Zampera, Brigitta Maison-Peteri, Sandrine Dulong, Jacques Beau, Virginie Hossard, Elisabeth Filipski, Franck Delaunay, Bruno Claustrat et al. · 2011 · Chronobiology International
20. Circadian clock effects on cellular proliferation: Insights from theory and experiments
    Shaon Chakrabarti, Franziska Michor · 2020 · Current Opinion in Cell Biology
21. Circadian Cycle-Dependent MeCP2 and Brain Chromatin Changes
    Alexia Martínez de Paz, Jose Vicente Sanchez-Mut, Mireia Samitier, Paolo Petazzi, Mauricio Sáez, Karolina Szczęsna, Dori Huertas, Manel Esteller, Juan Ausió · 2015 · PLoS ONE
22. Period2 downregulation inhibits glioma cell apoptosis by activating the MDM2-TP53 pathway
    Niu Zhanfeng, Wang Chengquan, Xia Hechun, Wang Jun, Zhang Lijian, Dede Ma, Liu Wenbin, Yin Lei · 2016 · Oncotarget
23. Complementary Therapies as a Strategy to Reduce Stress and Stimulate Immunity of Women With Breast Cancer
    Camila Aparecida Abrahão, E. Bomfim, L. C. Lopes-Júnior, G. Pereira-da-Silva · 2019 · Journal of Evidence-Based Integrative Medicine · Retracted
24. Circadian gene hClock enhances proliferation and inhibits apoptosis of human colorectal carcinoma cells in vitro and in vivo
    Ya-Ping Wang, Ruizhe Qian, Ning Sun, Chao Lü, Zongyou Chen, Luchun Hua · 2015 · Molecular Medicine Reports
25. The clock is ticking. Ageing of the circadian system: From physiology to cell cycle
    Eva Terzibasi-Tozzini, Antonio Martínez-Nicolás, Alejandro Lucas-Sánchez · 2017 · Seminars in Cell and Developmental Biology
26. Circadian molecular clocks tick along ontogenesis
    Alena Sumová, Zdeňka Bendová, Martin Sládek, Rehab E. El‐Hennamy, Kristýna Matějů, Lenka Polidarová, Serhiy Sosniyenko, Helena Illnerová · 2008 · Physiological Research
27. Genetic clock of biologic rhythms
    Corin Badiu · 2003 · Journal of Cellular and Molecular Medicine
28. Restoring circadian synchrony in vitro facilitates physiological responses to environmental chemicals
    Johanna Ndikung, Dorothe Storm, Norman Violet, Achim Kramer, Gilbert Schönfelder, Norman Ertych, Michael Oelgeschläger · 2019 · Environment International
29. Roles of NPAS2 in circadian rhythm and disease
    Luying Peng, Gaigai Bai, Yingxin Pang · 2021 · Acta Biochimica et Biophysica Sinica
30. Critical Roles of the Circadian Transcription Factor BMAL1 in Reproductive Endocrinology and Fertility
    Yin Jiang, Shiping Li, Wenming Xu, Junjie Ying, Yi Qu, Xiaohui Jiang, Ayuan Zhang, Yan Yue, Ruixi Zhou, Tiechao Ruan et al. · 2022 · Frontiers in Endocrinology
31. WOMEN IN CANCER THEMATIC REVIEW: Circadian rhythmicity and the influence of ‘clock’ genes on prostate cancer
    Zsófia Kiss, P. Ghosh · 2016 · Endocrine Related Cancer
32. Remodeling of the cycling transcriptome of the oyster Crassostrea gigas by the harmful algae Alexandrium minutum
    Laura Payton, Mickael Perrigault, Claire Hoede, Jean‐Charles Massabuau, Mohamedou Sow, Arnaud Huvet, Floriane Boullot, Caroline Fabioux, Hélène Hégaret, Damien Tran · 2017 · Scientific Reports
33. Emerging evidence for the interrelationship of xenobiotic exposure and circadian rhythms: a review
    Fei-Ling Lim, Richard A. Currie, G. Orphanides, Jonathan G. Moggs · 2006 · Xenobiotica
34. Maternal Control of the Fetal and Neonatal Rat Suprachiasmatic Nucleus
    Rehab E. El‐Hennamy, Kristýna Matějů, Zdeňka Bendová, Serhiy Sosniyenko, Alena Sumová · 2008 · Journal of Biological Rhythms
35. Circadian genes and risk of prostate cancer: Findings from the EPICAP study
    Méyomo Gaelle Wendeu-Foyet, Yves Akoli Koudou, Sylvie Cénée, Brigitte Trétarre, Xavier Rébillard, Géraldine Cancel‐Tassin, Olivier Cussenot, Anne Boland, Delphine Bacq, Jean‐François Deleuze et al. · 2019 · International Journal of Cancer
36. Transcriptional control of circadian metabolic rhythms in the liver
    S. Li, J. D. Lin · 2015 · Diabetes Obesity and Metabolism
37. OVEREXPRESSION OF BOTH CLOCK AND BMAL1 INHIBITS ENTRY TO S PHASE IN HUMAN COLON CANCER CELLS
    Wataru Sakamoto, Seiichi Takenoshita · 2015 · FUKUSHIMA JOURNAL OF MEDICAL SCIENCE
38. Uncovering the Proteome Response of the Master Circadian Clock to Light Using an AutoProteome System
    Ruijun Tian, Matías Alvarez-Saavedra, Hai‐Ying Mary Cheng, Daniel Figeys · 2011 · Molecular & Cellular Proteomics
39. An Overview of Genetic Polymorphisms and Pancreatic Cancer Risk in Molecular Epidemiologic Studies
    Yingsong Lin, Kiyoko Yagyu, Naoto Egawa, Makoto Ueno, Mitsuru Mori, Haruhisa Nakao, Hiroshi Ishii, Kozue Nakamura, Kenji Wakai, Satoyo Hosono et al. · 2010 · Journal of Epidemiology
40. Circadian genes polymorphisms, night work and prostate cancer risk: Findings from the EPICAP study
    Méyomo Gaelle Wendeu-Foyet, Sylvie Cénée, Yves Akoli Koudou, Brigitte Trétarre, Xavier Rébillard, Géraldine Cancel‐Tassin, Olivier Cussenot, Anne Boland, Robert Olaso, Jean‐François Deleuze et al. · 2020 · International Journal of Cancer
41. The circadian clock and hypoxia in tumor cell de-differentiation and metastasis
    Lasse D. Jensen · 2014 · Biochimica et Biophysica Acta (BBA) - General Subjects
42. Optimisation of time-scheduled regimen for anti-cancer drug infusion
    C. Basdevant, Jean Clairambault, Françis Lévi · 2005 · ESAIM Mathematical Modelling and Numerical Analysis
43. SIRT1 and circadian gene expression in pancreatic ductal adenocarcinoma: Effect of starvation
    Francesca Tavano, Valerio Pazienza, Andrea Fontana, Francesca Paola Burbaci, Concetta Panebianco, Chiara Saracino, Lucia Lombardi, Antonio De Bonis, Fabio F. di Mola, Pierluigi Di Sebastiano et al. · 2015 · Chronobiology International
44. Circadian clock and cell cycle: Cancer and chronotherapy
    Jing Yao, Chuqi He, Weichao Zhao, Nan Hu, Dingxin Long · 2021 · Acta Histochemica
45. Circadian rhythm and cell population growth
    Jean Clairambault, Stéphane Gaubert, Thomas Lepoutre · 2010 · Mathematical and Computer Modelling
46. Molecular control of circadian metabolic rhythms
    Siming Li, Jiandie D. Lin · 2009 · Journal of Applied Physiology
47. Chronobiological disruptions: unravelling the interplay of shift work, circadian rhythms, and vascular health in the context of stroke risk
    Xiaohong Li, Yanjin He, Dawu Wang, Mohammad Reza Momeni · 2024 · Clinical and Experimental Medicine
48. Cortisol Circadian Rhythm and Insulin Resistance in Muscle: Effect of Dosing and Timing of Hydrocortisone Exposure on Insulin Sensitivity in Synchronized Muscle Cells
    Mariarosaria Negri, Claudia Pivonello, Chiara Simeoli, Gilda Di Gennaro, Mary Anna Venneri, Francesca Sciarra, Rosario Ferrigno, Cristina de Angelis, Emilia Sbardella, Maria Cristina De Martino et al. · 2020 · Neuroendocrinology
49. Circadian time-dependent chemopreventive potential of withaferin-A in 7,12-dimethyl-benz[a]anthracene-induced oral carcinogenesis
    Shanmugam Manoharan, Panjamurthy Kuppusamy, S. Balakrishnan, Kalaiarasan Vasudevan, Lakshmanan Vellaichamy · 2009 · Pharmacological Reports
50. Rhythmic patterns in phagocytosis and the production of reactive oxygen species by zebrafish leukocytes
    Jessica E. Kaplan, Ryan Chrenek, Joel G. Morash, Catarina Ruksznis, Lynn G. Hannum · 2008 · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology
51. Profiling of circadian genes expressed in the uterus endometrial stromal cells of pregnant rats as revealed by DNA microarray coupled with RNA interference
    Hirotaka eTasaki · 2013 · Frontiers in Endocrinology
52. Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice
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53. The Circadian Gene Clock Plays an Important Role in Cell Apoptosis and the DNA Damage Response In Vitro
    Fan Wang, Caiyan Li, Yongluo, Lvan Chen · 2015 · Technology in Cancer Research & Treatment
54. Sleep Phase Delay in Cystic Fibrosis
    Judy L. Jensen, Christopher R. Jones, Christiana Kartsonaki, Kristyn A. Packer, Frederick R. Adler, Theodore G. Liou · 2017 · CHEST Journal
55. A Randomized Multicenter Study of Optimal Circadian Time of Vinorelbine Combined with Chronomodulated 5‐Fluorouracil in Pretreated Metastatic Breast Cancer Patients: EORTC Trial 05971
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56. Phase tracking and restoration of circadian rhythms by model-based optimal control
    O. S. Shaik, Sebastian Säger, Oliver Slaby, Dirk Lebiedz · 2008 · IET Systems Biology
57. Expression of phosphodiesterase 6 (PDE6) in human breast cancer cells
    Hongli Dong, Kevin P. Claffey, Stefan Brocke, Paul M. Epstein · 2013 · SpringerPlus
58. Light at night and health: the perils of rotating shift work
    Eva S. Schernhammer, Caroline A. Thompson · 2010 · Occupational and Environmental Medicine
59. Chemopreventive Doses of Methylselenocysteine Alter Circadian Rhythm in Rat Mammary Tissue
    Xun Zhang, Helmut Zarbl · 2008 · Cancer Prevention Research
60. A fluorescence spotlight on the clockwork development and metabolism of bone
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61. Circadian genes and risk of prostate cancer in the prostate cancer prevention trial
    Lisa W. Chu, Cathee Till, Baiyu Yang, Catherine M. Tangen, Phyllis J. Goodman, Kai Fun Yu, Yong Lian Zhu, Summer S. Han, Ashraful M. Hoque, Christine B. Ambrosone et al. · 2018 · Molecular Carcinogenesis
62. Associations of clock genes polymorphisms with soft tissue sarcoma susceptibility and prognosis
    Clara Benna, Senthilkumar Rajendran, Giovanna Spiro, Saveria Tropea, Paolo Del Fiore, Carlo Riccardo Rossi, Simone Mocellin M. D · 2018 · Journal of Translational Medicine
63. Dynamics of the mammalian cell cycle in physiological and pathological conditions
    Claude Gérard, Albert Goldbeter · 2015 · WIREs Systems Biology and Medicine
64. Night shift work and osteoporosis: evidence and hypothesis
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65. Cryptochromes modulate E2F family transcription factors
    Alanna B. Chan, Anne‐Laure Huber, Katja A Lamia · 2020 · Scientific Reports
66. The circadian modulation of leptin-controlled bone formation
    Loning Fu, Millan S. Patel, Gérard Karsenty · 2006 · Progress in brain research
67. Enhancement of NAD+-dependent SIRT1 deacetylase activity by methylselenocysteine resets the circadian clock in carcinogen-treated mammary epithelial cells
    Mingzhu Fang, Wei-Ren Guo, Youngil Park, Hwan‐Goo Kang, Helmut Zarbl · 2015 · Oncotarget
68. Complex dynamics in a synchronized cell-free genetic clock
    Lukas Aufinger, Johann Brenner, Friedrich Christian Simmel · 2022 · Nature Communications
69. Circadian Rhythm Disruption as a Contributor to Racial Disparities in Prostate Cancer
    Sonali S. Dasari, Maddison Archer, Nihal Mohamed, Ashutosh Kumar Tewari, Mariana G. Figueiro, Natasha Kyprianou · 2022 · Cancers
70. 24-Hour rhythms in oxidative stress during hepatocarcinogenesis in rats: effect of melatonin or α-ketoglutarate
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71. The Cell Cycle is a Limit Cycle
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72. Sleep quality and methylation status of core circadian rhythm genes among nurses and midwives
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73. Extracellular Acidosis Promotes Metastatic Potency via Decrease of the BMAL1 Circadian Clock Gene in Breast Cancer
    Yong-Jin Kwon, Eun-Bi Seo, Sun‐Ho Kwon, Song Hee Lee, Seul-Ki Kim, Sang Ki Park, Kyungjin Kim, Sae-Gwang Park, In‐Chul Park, Jong‐Wan Park et al. · 2020 · Cells
74. Influence of intermittent hypoxia on the signal transduction pathways to inflammatory response and circadian clock regulation
    Naoto Burioka, Satoru Koyanagi, Yasushi Fukuoka, Fumiyasu Okazaki, Takashi Fujioka, Naoki Kusunose, Masahiro Endo, Hisashi Suyama, Hiroki Chikumi, Shigehiro Ohdo et al. · 2009 · Life Sciences
75. Disturbance of circadian gene expression in endometrial cancer: Detection by real-time quantitative RT-PCR
    Hong-Chang Shih, Kong‐Bung Choo, Tien‐Jye Chang, Ming‐Yu Yang, Mu‐Chin Shih, Kun‐Tu Yeh, Ta‐Chih Liu, Shung-Feng Lin, Jan‐Gowth Chang · 2005 · Oncology Reports
76. Genome-Wide Association between Transcription Factor Expression and Chromatin Accessibility Reveals Regulators of Chromatin Accessibility
    David Lamparter, Daniel Marbach, Rico Rueedi, Sven Bergmann, Zoltán Kutalik · 2017 · PLoS Computational Biology
77. Small Molecules Targeting Biological Clock; A Novel Prospective for Anti-Cancer Drugs
    Sadia Rahman, Karlo Wittine, Mirela Sedić, Elitza Markova-Car · 2020 · Molecules
78. Timing of Novel Drug 1A-116 to Circadian Rhythms Improves Therapeutic Effects against Glioblastoma
    Laura Lucía Trebucq, Georgina Alexandra Cardama, Pablo Lorenzano Menna, Diego Andres Golombek, Juan José Chiesa, Luciano Marpegán · 2021 · Pharmaceutics
79. Understanding the significance of biological clock and its impact on cancer incidence
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80. Circadian rhythms, adrenergic hormones and trafficking of hematopoietic stem cells
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81. Chronotype and risk of post-menopausal endometrial cancer in the California Teachers Study
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82. The multifaceted impact of circadian disruption on cancer risk: a systematic review of insights and economic implications
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83. Crosstalk between Circadian Rhythm Dysregulation and Tumorigenesis, Tumor Metabolism and Tumor Immune Response
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84. Altered Phase-Relationship between Peripheral Oscillators and Environmental Time in Cry1 or Cry2 Deficient Mouse Models for Early and Late Chronotypes
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85. Flatness-Based Control of PER Protein Oscillations in a Drosophila Model
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86. Prognostic relevance of melanoma antigen D1 expression in colorectal carcinoma
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87. Estradiol differently affects melanin synthesis of malignant and normal melanocytes: a relationship with clock and clock-controlled genes
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88. l-Theanine inhibits melanoma cell growth and migration via regulating expression of the clock gene BMAL1
    Ruyi Zhang, Shuangning Zheng, Zhen Guo, Yanan Wang, Guocui Yang, Zhimin Yin, Lan Luo · 2021 · European Journal of Nutrition
89. A Comparative Study of Gene-Expression Data of Basal Cell Carcinoma and Melanoma Reveals New Insights about the Two Cancers
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90. Losing Sleep Over Cancer
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91. Sleep interruption associated with house staff work schedules alters circadian gene expression
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92. Metastasis-associated protein 1 is an integral component of the circadian molecular machinery
    Da‐Qiang Li, Suresh B. Pakala, Sirigiri Divijendra Natha Reddy, Shaohua Peng, Seetharaman Balasenthil, Chu‐Xia Deng, Cheng Chi Lee, Michael A. Rea, Rakesh Kumar · 2013 · Nature Communications
93. Analysis of the Circadian Regulation of Cancer Hallmarks by a Cross-Platform Study of Colorectal Cancer Time-Series Data Reveals an Association with Genes Involved in Huntington’s Disease
    Müge Yalçın, Rukeia El‐Athman, Koliane Ouk, Josef Priller, Angela Relógio · 2020 · Cancers
94. Rhythm changes of clock genes, apoptosis-related genes and atherosclerosis-related genes in apolipoprotein E knockout mice
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95. Why Life Oscillates - Biological Rhythms and Health
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96. The Stem Cell Division Theory of Cancer
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97. Comparison of circadian characteristics for cytotoxic lymphocyte subsets in non-small cell lung cancer patients versus controls
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98. Circadian Rhythm Dysregulation and Leukemia Development: The Role of Clock Genes as Promising Biomarkers
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99. Nuclear receptor modulators inhibit osteosarcoma cell proliferation and tumour growth by regulating the mTOR signaling pathway
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100. Chronobiology in mammalian health
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