Hypoxia signalling through mTOR and the unfolded protein response in cancer

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Items 101–200 of 884

1. Unfolded protein response (UPR) integrated signaling networks determine cell fate during hypoxia
   Sylwia Bartoszewska, James F. Collawn · 2020 · Cellular & Molecular Biology Letters
2. Hypoxia-Driven Effects in Cancer: Characterization, Mechanisms, and Therapeutic Implications
   Rachel Shi, Chengheng Liao, Qing Hua Zhang · 2021 · Cells
3. Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment
   Susan E. Scanlon, Peter M. Glazer · 2015 · DNA repair
4. The Tumor Microenvironment in Tumorigenesis and Therapy Resistance Revisited
   Dzobo, Kevin, Senthebane, Dimakatso A., Dandara, Collet · 2023 · Cancers
5. mTOR Cross-Talk in Cancer and Potential for Combination Therapy
   Fabiana Conciatori, Ludovica Ciuffreda, Chiara Bazzichetto, Italia Falcone, Sara Pilotto, Emilio Bria, Francesco Cognetti, Michèle Milella · 2018 · Cancers
6. ER Stress Negatively Modulates the Expression of the miR-199a/214 Cluster to Regulates Tumor Survival and Progression in Human Hepatocellular Cancer
   Quanlu Duan, Xingxu Wang, Wei Gong, Li Ni, Chen Chen, Xingxing He, Fuqiong Chen, Lei Yang, Peihua Wang, Dao Wen Wang · 2012 · PLoS ONE
7. Hypoxia-induced metabolic shifts in cancer cells: Moving beyond the Warburg effect
   Aalim M. Weljie, Frank Robert Jirik · 2010 · The International Journal of Biochemistry & Cell Biology
8. Autophagy is required during cycling hypoxia to lower production of reactive oxygen species
   Kasper M. A. Rouschop, Chantal H.M.A. Ramaekers, Marco B.E. Schaaf, Tom G. Keulers, Kim G.M. Savelkouls, Philippe Lambin, Marianne Koritzinsky, Bradly G. Wouters · 2009 · Radiotherapy and Oncology
9. The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism
   Yingfeng Deng, Zhao V. Wang, Caroline Tao, Ningguo Gao, William L. Holland, Anwarul Ferdous, Joyce J. Repa, Guosheng Liang, Jin Ye, Mark A. Lehrman et al. · 2012 · Journal of Clinical Investigation
10. Hypoxia-Induced Gene Expression in Chemoradioresistant Cervical Cancer Revealed by Dynamic Contrast-Enhanced MRI
    Cathinka Halle, Erlend K. F. Andersen, Malin Lando, Eva‐Katrine Aarnes, Grete Hasvold, Marit Holden, Randi G. Syljuåsen, Kolbein Sundfør, Gunnar Balle Kristensen, Ruth Holm et al. · 2012 · Cancer Research
11. Impact of Metabolism in on T-Cell Differentiation and Function and Cross Talk with Tumor Microenvironment
    Soumaya Kouidhi, Amel Benammar Elgaaïed, Salem Chouaı̈b · 2017 · Frontiers in Immunology
12. Hypoxia causes triglyceride accumulation via HIF-1-mediated stimulation of lipin 1 expression
    Ilias Mylonis, Hiroshi Sembongi, Christina D. Befani, Panagiotis Liakos, Symeon Siniossoglou, George Simos · 2012 · Journal of Cell Science
13. Two phases of disulfide bond formation have differing requirements for oxygen
    Koritzinsky, Marianne, Levitin, Fiana, van den Beucken, Twan, Rumantir, Ryan A., Harding, Nicholas J., Chu, Kenneth C., Boutros, Paul C., Braakman, Ineke, Wouters, Bradly G. · 2013 · Journal of Cell Biology
14. mTOR Signal and Hypoxia-Inducible Factor-1α Regulate CD133 Expression in Cancer Cells
    KAZUKO Y. MATSUMOTO, Tokuzo Arao, Kaoru Tanaka, Hiroyasu Kaneda, Kanae Kudo, Yoshihiko Fujita, Daisuke Tamura, Keiichi Aomatsu, Tomohide Tamura, Yasuhide Yamada et al. · 2009 · Cancer Research
15. Hypoxia-Inducible Factor-1: A Critical Player in the Survival Strategy of Stressed Cells
    Shuyang Chen, Nianli Sang · 2015 · Journal of Cellular Biochemistry
16. Inhibition of Akt/mTOR Attenuates Age-Related Changes in Mesenchymal Stem Cells
    Borzo Gharibi, Samira Farzadi, Mandeep S. Ghuman, Francis J. Hughes · 2014 · Stem Cells
17. The mTOR Pathway in Hepatic Malignancies
    Mamatha Bhat, Nahum Sonenberg, Gregory James Gores · 2013 · Hepatology
18. A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients
    Rodenhizer, Darren, Gaude, Edoardo, Cojocari, Dan, Mahadevan, Radhakrishnan, Frezza, Christian, Wouters, Bradly G., McGuigan, Alison P. · 2016 · Nature Materials
19. An emerging role for TOR signaling in mammalian tissue and stem cell physiology
    Ryan Charles Russell, Chong Fang, Kun‐Liang Guan · 2011 · Development
20. Targeting the ATF4 pathway in cancer therapy
    Dean C. Singleton, Adrian Llewellyn Harris · 2012 · Expert Opinion on Therapeutic Targets
21. The oral iron chelator deferasirox represses signaling through the mTOR in myeloid leukemia cells by enhancing expression of REDD1
    Junko H. Ohyashiki, Chiaki Kobayashi, Ryoko Hamamura, Seiichi Okabe, Tetsuzo Tauchi, Kazuma Ohyashiki · 2009 · Cancer Science
22. Cell intrinsic and extrinsic activators of the unfolded protein response in cancer: Mechanisms and targets for therapy
    Feven Tameire, Ioannis I. Verginadis, Constantinos Koumenis · 2015 · Seminars in Cancer Biology
23. Tumour Hypoxia-Mediated Immunosuppression: Mechanisms and Therapeutic Approaches to Improve Cancer Immunotherapy
    Zhe Fu, Alexandra M. Mowday, Jeff Bruce Smaill, Ian F. Hermans, Adam Vorn Patterson · 2021 · Cells
24. Hepatocellular Carcinoma Mechanisms Associated with Chronic HCV Infection and the Impact of Direct-Acting Antiviral Treatment
    Srikanta Dash, Yücel Aydın, Kyle Widmer, Leela Nayak · 2020 · Journal of Hepatocellular Carcinoma
25. Molecular and cellular basis for the unique functioning of Nrf1, an indispensable transcription factor for maintaining cell homoeostasis and organ integrity
    Yiguo Zhang, Yuancai Xiang · 2016 · Biochemical Journal
26. Nicotine: specific role in angiogenesis, proliferation and apoptosis
    Alessio Cardinale, Candida Nastrucci, Alfredo Cesario, Patrizia Russo · 2011 · Critical Reviews in Toxicology
27. Stress-mediated translational control in cancer cells
    Gabriel Leprivier, Barak Rotblat, Debjit Khan, Eric Jan, Poul H. B. Sorensen · 2014 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
28. PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR)
    Philip Kranz, Fabian Neumann, Alexandra Wolf, Fabian Classen, Mosche Pompsch, Tobias Ocklenburg, Jennifer Baumann, Kirsten Janke, Melanie Baumann, Kirsten Göpelt et al. · 2017 · Cell Death and Disease
29. “Contextual” Synthetic Lethality and/or Loss of Heterozygosity: Tumor Hypoxia and Modification of DNA Repair
    Norman Hok Ling Chan, Robert Glen Bristow · 2010 · Clinical Cancer Research
30. The hypoxia response pathway and <i>β</i> ‐cell function
    Cantley, J., Grey, S. T., Maxwell, P. H., Withers, D. J. · 2010 · Diabetes, Obesity and Metabolism
31. Translational control of breast cancer plasticity
    Michael Jewer, Laura J. Lee, Matthew Leibovitch, Guihua Zhang, Jiahui Liu, Scott D. Findlay, Krista Marie Vincent, Kristofferson V. Tandoc, Dylan Z. Dieters‐Castator, Daniela F. Quail et al. · 2020 · Nature Communications
32. Targeting Oxidative Phosphorylation to Increase the Efficacy of Radio- and Immune-Combination Therapy
    Daan F. Boreel, Paul N. Span, Sandra Heskamp, Gosse J. Adema, Johan Bussink · 2021 · Clinical Cancer Research
33. mTOR is required for pulmonary arterial vascular smooth muscle cell proliferation under chronic hypoxia
    Vera P. Krymskaya, Jennifer Snow, Gregory Cesarone, Irene Khavin, Dmitry A. Goncharov, Poay N. Lim, Sigrid C. Veasey, Kaori Ihida‐Stansbury, Peter Lloyd Jones, Elena A. Goncharova · 2011 · The FASEB Journal
34. miR-199a Links MeCP2 with mTOR Signaling and Its Dysregulation Leads to Rett Syndrome Phenotypes
    Keita Tsujimura, Koichiro Irie, Hideyuki Nakashima, Yoshihiro Egashira, Yoichiro Fukao, Masayuki Fujiwara, Masayuki Itoh, Masahiro Uesaka, Takuya Imamura, Yasukazu Nakahata et al. · 2015 · Cell Reports
35. Membrane protein CNNM4–dependent Mg2+ efflux suppresses tumor progression
    Yosuke Funato, Daisuke Yamazaki, Shin Mizukami, Lisa Du, Kazuya Kikuchi, Hiroaki Miki · 2014 · Journal of Clinical Investigation
36. Akt Determines Cell Fate Through Inhibition of the PERK-eIF2α Phosphorylation Pathway
    Zineb Mounir, Jothilatha Krishnamoorthy, Shuo Wang, Barbara Papadopoulou, Shirley L. Campbell, William J. Muller, Maria Hatzoglou, Antonis E. Koromilas · 2011 · Science Signaling
37. Germinal Center Hypoxia Potentiates Immunoglobulin Class Switch Recombination
    Robert K. Abbott, Molly Thayer, Jasmine C. Labuda, Murillo Silva, Phaethon Philbrook, Derek W. Cain, Hidefumi Kojima, Stephen Matthew Hatfield, Shalini Sethumadhavan, Akio Ohta et al. · 2016 · The Journal of Immunology
38. Class I HDAC inhibitors enhance YB‐1 acetylation and oxidative stress to block sarcoma metastasis
    Amal M. El-Naggar, Syam Prakash Somasekharan, Yemin Wang, Hongwei Cheng, Gian Luca Negri, Melvin Pan, Xue Q. Wang, Alberto Delaidelli, Bo Rafn, Jordan Cran et al. · 2019 · EMBO Reports
39. Evidence of endoplasmic reticulum stress and protein synthesis inhibition in the placenta of non‐native women at high altitude
    Yung, Hong Wa, Cox, Mathew, van Patot, Martha Tissot, Burton, Graham J. · 2012 · The FASEB Journal
40. Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium
    Erik O. Pettersen, Peter Ebbesen, Roben G. Gieling, Kaye Janine Williams, Ludwig Jerome Dubois, Philippe Lambin, Carol Ward, James Meehan, Ian H. Kunkler, Simon P. Langdon et al. · 2014 · Journal of Enzyme Inhibition and Medicinal Chemistry
41. SERPINB3 and B4: From biochemistry to biology
    Yu Sun, Namratha Sheshadri, Wei‐Xing Zong · 2016 · Seminars in Cell and Developmental Biology
42. Adaptive Stress Responses During Tumor Metastasis and Dormancy
    Daniela Senft, Ze’ev A. Ronai · 2016 · Trends in cancer
43. Drug-Loaded Polymeric Nanoparticles for Cancer Stem Cell Targeting
    Binbin Li, Qinghua Li, Jingxin Mo, Honglian Dai · 2017 · Frontiers in Pharmacology
44. Cellular quiescence: are controlling genes conserved?
    Yanagida, Mitsuhiro · 2009 · Trends in Cell Biology
45. Lysine Demethylase LSD1 Coordinates Glycolytic and Mitochondrial Metabolism in Hepatocellular Carcinoma Cells
    Akihisa Sakamoto, Shinjiro Hino, Katsuya Nagaoka, Kotaro Anan, Ryuta Takase, Haruka Matsumori, Hidenori Ojima, Yae Kanai, Kazunori Arita, Mitsuyoshi Nakao · 2015 · Cancer Research
46. Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling
    Meng‐Ju Wu, Chia-Ing Jan, Yeou‐Guang Tsay, Yau‐Hua Yu, Chih‐Yang Huang, Shu‐Chun Lin, Chung‐Ji Liu, Yu−Syuan Chen, Jeng‐Fan Lo, Cheng-Chia Yu · 2010 · Molecular Cancer
47. Resistance to mTORC1 Inhibitors in Cancer Therapy: From Kinase Mutations to Intratumoral Heterogeneity of Kinase Activity
    Seraina Faes, Nicolas Demartines, Olivier Dormond · 2017 · Oxidative Medicine and Cellular Longevity
48. Oxygen Sensing and Integrative Stress Signaling in Plants
    Romy Schmidt, Daan A. Weits, Claudio F. J. Feulner, Joost Thomas van Dongen · 2017 · PLANT PHYSIOLOGY
49. Unravelling mitochondrial pathways to P arkinson's disease
    Ivana Celardo, L. Miguel Martins, Sonia Gandhi · 2013 · British Journal of Pharmacology
50. Signaling pathways and mechanisms of hypoxia‐induced autophagy in the animal cells
    Yungyun Fang, Jin Tan, Qiang Zhang · 2015 · Cell Biology International
51. Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
    Siquan Chen, Jonathan L. Blank, Theodore Peters, Xiaozhen J. Liu, David M. Rappoli, Michael D. Pickard, Saurabh Menon, Jie Yu, Denise L. Driscoll, Trupti Lingaraj et al. · 2010 · Cancer Research
52. LAMP3 is involved in tamoxifen resistance in breast cancer cells through the modulation of autophagy
    Anika Nagelkerke, Anieta M. Sieuwerts, Johan Bussink, Fred C.G.J. Sweep, Maxime P. Look, John A. Foekens, John W.M. Martens, Paul N. Span · 2014 · Endocrine Related Cancer
53. Role of Hypoxia-Mediated Autophagy in Tumor Cell Death and Survival
    Rania Faouzi Zaarour, Bilal Azakir, Edries Yousaf Hajam, Husam Hussein Nawafleh, Nagwa Ahmed Zeinelabdin, Agnete S. T. Engelsen, Jérôme Thiery, Colin Jamora, Salem Chouaı̈b · 2021 · Cancers
54. Nanomedicine Strategies in Conquering and Utilizing the Cancer Hypoxia Environment
    Yi Pan, Longcai Liu, Xiaozhou Mou, Yu Cai · 2023 · ACS Nano
55. Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition
    Kenichi Tamama, Haruhisa Kawasaki, Svetoslava S. Kerpedjieva, Jianjun Guan, Ramesh Kumar Ganju, Chandan K. Sen · 2010 · Journal of Cellular Biochemistry
56. Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3
    Hilda Mujčić, Tomasz Rzymski, Kasper M. A. Rouschop, Marianne Koritzinsky, Manuela Milani, Adrian Llewellyn Harris, Bradly G. Wouters · 2009 · Radiotherapy and Oncology
57. Hypoxia counteracts taxol-induced apoptosis in MDA-MB-231 breast cancer cells: role of autophagy and JNK activation
    Annick Notte, Noëlle Ninane, Thierry Arnould, Carine Michiels · 2013 · Cell Death and Disease
58. Autophagy: An adaptive metabolic response to stress shaping the antitumor immunity
    Elodie Viry, Jérôme Paggetti, Joanna Bagińska, Takouhie Mgrditchian, Guy Berchem, Etienne Moussay, Bassam Janji · 2014 · Biochemical Pharmacology
59. Crosstalk between endoplasmic reticulum stress and oxidative stress: a dynamic duo in multiple myeloma
    Sinan Xiong, Wee Joo Chng, Jianbiao Zhou · 2021 · Cellular and Molecular Life Sciences
60. Placental Adaptation to Early-Onset Hypoxic Pregnancy and Mitochondria-Targeted Antioxidant Therapy in a Rodent Model
    Anna Maria Nuzzo, Emily J. Camm, Amanda Nancy Sferruzzi-Perri, Thomas J. Ashmore, Hong Wa Yung, Tereza Cindrová‐Davies, Ana‐Mishel Spiroski, Megan R. Sutherland, Angela Logan, Shani Austin‐Williams et al. · 2018 · American Journal Of Pathology
61. Hypoxia signaling and resistance in C. elegans
    Jo Anne Powell‐Coffman · 2010 · Trends in Endocrinology and Metabolism
62. Discovery of a Novel Unfolded Protein Response Phenotype of Cancer Stem/Progenitor Cells from the Bone Marrow of Breast Cancer Patients
    Kai Bartkowiak, Katharina E. Effenberger, Sönke Harder, Antje Andreas, Friedrich Buck, Jasna Peter‐Katalinić, Klaus Pantel, Burkhard Brandt · 2010 · Journal of Proteome Research
63. Tissue-Type Plasminogen Activator Regulates the Neuronal Uptake of Glucose in the Ischemic Brain
    F. Wu, Jialing Wu, Andrew Nicholson, Ramiro Echeverry, Woldeab B. Haile, Marcela Catano, Jie An, A. K. Lee, Duc Minh Duong, Eric B. Dammer et al. · 2012 · Journal of Neuroscience
64. Bisphosphonates suppress insulin‐like growth factor 1‐induced angiogenesis via the HIF‐1α/VEGF signaling pathways in human breast cancer cells
    Xudong Tang, Qunzhou Zhang, Shihong Shi, Yun Yen, Xiangyong Li, Yuefei Zhang, Keyuan Zhou, Anh D. Le · 2009 · International Journal of Cancer
65. Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis
    Koichi Murata, Celestia Fang, Chikashi C. Terao, Ευγενία Γιαννοπούλου, Ye Ji Lee, Min Joon Lee, Se Hwan Mun, Seyeon Bae, Yu Qiao, Ruoxi Yuan et al. · 2017 · Immunity
66. Impaired Mitochondrial Fat Oxidation Induces FGF21 in Muscle
    Vandanmagsar, Bolormaa, Warfel, Jaycob D., Wicks, Shawna E., Ghosh, Sujoy, Salbaum, J. Michael, Burk, David, Dubuisson, Olga S., Mendoza, Tamra M., Zhang, Jingying, Noland, Robert C. et al. · 2016 · Cell Reports
67. Synthesis and biological evaluation of a 99mTc-labelled sulfonamide conjugate for in vivo visualization of carbonic anhydrase IX expression in tumor hypoxia
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68. Modulating mTOR in Aging and Health
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69. The regulation of interleukin‐6 implicates skeletal muscle as an integrative stress sensor and endocrine organ
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70. Inhibition of GSK3B Bypass Drug Resistance of p53-Null Colon Carcinomas by Enabling Necroptosis in Response to Chemotherapy
    Emanuela Grassilli, Robert Narloch, Elena A. Federzoni, Leonarda Ianzano, Fabio Pisano, Roberto Giovannoni, Gabriele Romano, Laura Masiero, Biagio Eugenio Leone, Serena Bonin et al. · 2013 · Clinical Cancer Research
71. Lipid biology of breast cancer
    Jan Baumann, Christopher J. Sevinsky, Douglas S. Conklin · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
72. Sleep apnea and the subsequent risk of breast cancer in women: a nationwide population-based cohort study
    Chang, Wei-Pin, Liu, Mu-En, Chang, Wei-Chiao, Yang, Albert C., Ku, Yan-Chiou, Pai, Jei-Tsung, Lin, Yea-Wen, Tsai, Shih-Jen · 2014 · Sleep Medicine
73. The mTOR Signaling Pathway in the Brain: Focus on Epilepsy and Epileptogenesis
    E. Russo, R. Citraro, A. Constanti, G. De Sarro · 2012 · Molecular Neurobiology
74. Immunometabolic Phenotype Alterations Associated with the Induction of Disease Tolerance and Persistent Asymptomatic Infection of Salmonella in the Chicken Intestine
    Michael H. Kogut, Ryan J. Arsenault · 2017 · Frontiers in Immunology
75. Gene Dosage, Expression, and Ontology Analysis Identifies Driver Genes in the Carcinogenesis and Chemoradioresistance of Cervical Cancer
    Malin Lando, Marit Holden, Linn Cecilie Bergersen, Debbie Hege Svendsrud, Trond Stokke, Kolbein Sundfør, Ingrid K. Glad, Gunnar Balle Kristensen, Heidi Lyng · 2009 · PLoS Genetics
76. Hypoxia and HIF-1 activation in bacterial infections
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77. Mechanisms for Tuning Engineered Nanomaterials to Enhance Radiation Therapy of Cancer
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78. Radiobiological hypoxia, histological parameters of tumour microenvironment and local tumour control after fractionated irradiation
    Ala Yaromina, Howard D. Thames, Xuanjing Zhou, Sandra Hering, Wolfgang Eicheler, Annegret Dörfler, Thomas Leichtner, Daniel Zips, Michael A. Baumann · 2010 · Radiotherapy and Oncology
79. Novel Approaches for Molecular Targeted Therapy of Breast Cancer: Interfering with PI3K/AKT/mTOR Signaling
    Thomas W. Grunt, Gabriella Lucia Mariani · 2013 · Current Cancer Drug Targets
80. Gene expression and hypoxia in breast cancer
    Elena Favaro, Simon Lord, Adrian Llewellyn Harris, Francesca Meteora Buffa · 2011 · Genome Medicine
81. Hypoxia increases genome-wide bivalent epigenetic marking by specific gain of H3K27me3
    Peggy Prickaerts, Michiel E. Adriaens, Twan van den Beucken, Elizabeth Koch, Ludwig Jerome Dubois, Vivian E.H. Dahlmans, Caroline M.M. Gits, Chris T. Evelo, Michelle Chan‐Seng‐Yue, Bradly G. Wouters et al. · 2016 · Epigenetics & Chromatin
82. NCAPD2 inhibits autophagy by regulating Ca2+/CAMKK2/AMPK/mTORC1 pathway and PARP-1/SIRT1 axis to promote colorectal cancer
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83. Stanniocalcin 2 (STC2): a universal tumour biomarker and a potential therapeutical target
    Shuo Qie, Nianli Sang · 2022 · Journal of Experimental & Clinical Cancer Research
84. Stanniocalcin-2 promotes epithelial–mesenchymal transition and invasiveness in hypoxic human ovarian cancer cells
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85. Small-Molecule Activation of p53 Blocks Hypoxia-Inducible Factor 1α and Vascular Endothelial Growth Factor Expression In Vivo and Leads to Tumor Cell Apoptosis in Normoxia and Hypoxia
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86. Metformin attenuates graft-versus-host disease via restricting mammalian target of rapamycin/signal transducer and activator of transcription 3 and promoting adenosine monophosphate–activated protein kinase-autophagy for the balance between T helper 17 and Tregs
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87. Navigating tumor angiogenesis: therapeutic perspectives and myeloid cell regulation mechanism
    Fan Yang, Gloria Lee, Yi Fan · 2024 · Angiogenesis
88. Hypoxia and Predicting Radiation Response
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89. Recent advances in the genetics of SDH-related paraganglioma and pheochromocytoma
    Erik Frans Hensen, Jean‐Pierre Bayley · 2010 · Familial Cancer
90. Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein
    Ankita Burman, Jonathan A. Kropski, Carla L. Calvi, Ana Paula Moreira Serezani, Bruno D. Pascoalino, Wei Han, Taylor P. Sherrill, Linda A. Gleaves, William E. Lawson, Lisa R. Young et al. · 2018 · JCI Insight
91. MicroRNA-135b acts as a tumor promoter by targeting the hypoxia-inducible factor pathway in genetically defined mouse model of head and neck squamous cell carcinoma
    Lu Zhang, Zhi‐Jun Sun, Yansong Bian, Ashok B. Kulkarni · 2013 · Cancer Letters
92. Hypoxia and hypoxia-inducible factors in neuroblastoma
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93. pVHL/HIF-Regulated CD70 Expression Is Associated with Infiltration of CD27+ Lymphocytes and Increased Serum Levels of Soluble CD27 in Clear Cell Renal Cell Carcinoma
    Melanie Ruf, Christiane Mittmann, Anna M. Nowicka, Arndt Hartmann, Thomas Hermanns, Cédric Poyet, Maries F. van den Broek, Tullio Sulser, Holger Moch, Peter Schraml · 2015 · Clinical Cancer Research
94. Population Genomics Reveals Low Genetic Diversity and Adaptation to Hypoxia in Snub-Nosed Monkeys
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95. Cancer stem cells with increased metastatic potential as a therapeutic target for esophageal cancer
    D. Wang, John Th. M. Plukker, Robert Paul Coppes · 2017 · Seminars in Cancer Biology
96. Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer
    Jeroen E. J. Guikema, Martine Amiot, Eric Eldering · 2017 · Expert Opinion on Therapeutic Targets
97. Immunoexpression Status and Prognostic Value of mTOR and Hypoxia-Induced Pathway Members in Primary and Metastatic Clear Cell Renal Cell Carcinomas
    Luciana Schultz, Alcides Chaux, Roula Albadine, Jessica L Hicks, Jaeyeon Kim, Angelo Michael De Marzo, Mohamad Ezzeddine Allaf, Michael Anthony Carducci, Ronald Rodríguez, Hans-Joerg Hammers et al. · 2011 · The American Journal of Surgical Pathology
98. Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response
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99. TOR Signaling Couples Oxygen Sensing to Lifespan in C. elegans
    Michael Schieber, Navdeep S. Chandel · 2014 · Cell Reports
100. Mammalian Target of Rapamycin (mTOR) Regulates Cellular Proliferation and Tumor Growth in Urothelial Carcinoma
     Donna Elizabeth Hansel, Eric Platt, Mohammed S. Orloff, Jyoti Harwalker, S. Sethu, Jessica L Hicks, Angelo De Marzo, Roxanne Steinle, Eric D. Hsi, Dan Theodorescu et al. · 2010 · American Journal Of Pathology