Hypoxia signalling through mTOR and the unfolded protein response in cancer

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4. Hypoxia-Induced Invadopodia Formation Involves Activation of NHE-1 by the p90 Ribosomal S6 Kinase (p90RSK)
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6. Secreted IGFBP5 mediates mTORC1-dependent feedback inhibition of IGF-1 signalling
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9. Hypoxia-Induced Modulation of Apoptosis and BCL-2 Family Proteins in Different Cancer Cell Types
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11. Induction of the Unfolded Protein Response Drives Enhanced Metabolism and Chemoresistance in Glioma Cells
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16. Hypoxia-inducible factor (HIF) network: insights from mathematical models
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17. Brucine, an indole alkaloid from Strychnos nux-vomica attenuates VEGF-induced angiogenesis via inhibiting VEGFR2 signaling pathway in vitro and in vivo
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22. Magnesium and its transporters in cancer: a novel paradigm in tumour development
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24. Hypoxia-induced Expression of Carbonic Anhydrase 9 Is Dependent on the Unfolded Protein Response
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25. Productive Parvovirus B19 Infection of Primary Human Erythroid Progenitor Cells at Hypoxia Is Regulated by STAT5A and MEK Signaling but not HIFα
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29. Targeting Hypoxia-Driven Metabolic Reprogramming to Constrain Tumor Progression and Metastasis
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30. Emerging mechanisms of the unfolded protein response in therapeutic resistance: from chemotherapy to Immunotherapy
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33. Hypoxia disrupts proteostasis in Caenorhabditis elegans
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34. Dormancy of Cancer Cells with Suppression of AKT Activity Contributes to Survival in Chronic Hypoxia
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37. Hypoxia as a target for tissue specific gene therapy
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38. The molecular therapy of colorectal cancer
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39. BAY 87–2243, a novel inhibitor of hypoxia-induced gene activation, improves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts
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41. mTOR Signaling in Kidney Diseases
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42. Novel gas‐based nanomedicines for cancer therapy
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44. A Seven-Gene Set Associated with Chronic Hypoxia of Prognostic Importance in Hepatocellular Carcinoma
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46. Hypoxia-Inducible Factor 1 Regulation through Cross Talk between mTOR and MT1-MMP
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49. Hypoxia induces a phase transition within a kinase signaling network in cancer cells
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52. Inhibition of Chondrosarcoma Growth by mTOR Inhibitor in an In Vivo Syngeneic Rat Model
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53. Hypoxia, Lactate Accumulation, and Acidosis: Siblings or Accomplices Driving Tumor Progression and Resistance to Therapy?
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54. Endoplasmic Reticulum Stress Pathway, the Unfolded Protein Response, Modulates Immune Function in the Tumor Microenvironment to Impact Tumor Progression and Therapeutic Response
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56. Constitutive stabilization of hypoxia-inducible factor alpha selectively promotes the self-renewal of mesenchymal progenitors and maintains mesenchymal stromal cells in an undifferentiated state
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57. Stress in the kidney is the road to pERdition: is endoplasmic reticulum stress a pathogenic mediator of diabetic nephropathy?
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58. Western blotting revisited: Critical perusal of underappreciated technical issues
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59. Prognostic role of hypoxia-inducible factor-2α tumor cell expression in cancer patients: a meta-analysis
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60. Rationale for Combining Radiotherapy and Immune Checkpoint Inhibition for Patients With Hypoxic Tumors
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63. Targeted Inhibition of Glutamine-Dependent Glutathione Metabolism Overcomes Death Resistance Induced by Chronic Cycling Hypoxia
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64. Role of mTORC1 Controlling Proteostasis after Brain Ischemia
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69. Hypoxia Induces Autophagy through Translational Up-Regulation of Lysosomal Proteins in Human Colon Cancer Cells
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70. Rapamycin Treatment Improves Neuron Viability in an In Vitro Model of Stroke
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71. Calreticulin Ins5 and Del52 mutations impair unfolded protein and oxidative stress responses in K562 cells expressing CALR mutants
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73. Suppression of Hypoxia-Inducible Factor 1α (HIF-1α) by Tirapazamine Is Dependent on eIF2α Phosphorylation Rather Than the mTORC1/4E-BP1 Pathway
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78. Extracellular Vesicles as Transmitters of Hypoxia Tolerance in Solid Cancers
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79. Drosophila Genome-Wide RNAi Screen Identifies Multiple Regulators of HIF–Dependent Transcription in Hypoxia
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81. RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect
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