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Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion

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Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma

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Stimulation of Bone Formation in Vitro and in Rodents by Statins

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Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

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A Pooled Analysis of Bone Marrow Micrometastasis in Breast Cancer

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DQIS — Distributed Quorum-Based Independent Immune Surveillance: A Theoretical Framework for Byzantine Fault Tolerance for Multi-Channel Immune Surveillance

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Clonal diversity shapes the tumour microenvironment leading to distinct immunotherapy responses in metastatic urothelial carcinoma

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Integrated analysis of FKBP1A/SLC3A2 axis in everolimus inducing ferroptosis of breast cancer and anti-proliferation of T lymphocyte

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Hyaluronic acid metabolism and chemotherapy resistance: recent advances and therapeutic potential

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Targeting lipid biosynthesis on the basis of conventional treatments for clear cell renal cell carcinoma: A promising therapeutic approach

Guo, T., Zhang, X., Chen, S., Wang, X., & Wang, X. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.122329 · Cited by 11

Application of microfluidic systems in management of head and neck squamous cell carcinoma

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Nanoscale imaging of the adhesion core including integrin β1 on intact living cells using scanning electron-assisted dielectric-impedance microscopy

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Suppression of αvβ6 downregulates P-glycoprotein and sensitizes multidrug-resistant breast cancer cells to anticancer drugs

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The Importance of Cancer-Associated Fibroblasts in the Pathogenesis of Head and Neck Cancers

Raudenská, M., Svobodová, M., Gumulec, J., Falk, M., & Masařík, M. (2020) · Klinicka onkologie · doi:10.14735/amko202039 · Cited by 10

Molecular Targeting of Integrins and Integrin-Associated Signaling Networks in Radiation Oncology

Vehlow, A., Storch, K., Matzke, D., & Cordes, N. (2016) · Recent results in cancer research/Recent Results in Cancer Research · doi:10.1007/978-3-662-49651-0_4 · Cited by 10

The Role of Pretreatment Serum Neutrophil-to-Lymphocyte Ratio in Hypopharyngeal Cancer Treated with Definitive Chemoradiotherapy: A Pilot Study

Kuo, C., Hsueh, W., Wu, Y.-H., Yang, M.-W., Cheng, Y., Pao, T.-H., & Tsai, M. (2019) · Scientific Reports · doi:10.1038/s41598-018-38282-z · Cited by 10

Exploring in vitro modeling in hepatocarcinogenesis research: morphological and molecular features and similarities to the corresponding human disease

Valente, L. C., Bacil, G. P., Riechelmann-Casarin, L., Barbosa, G. C., Barbisan, L. F., & Romualdo, G. R. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.122781 · Cited by 9

Silencing of LRRFIP1 enhances the sensitivity of gemcitabine in pancreatic cancer cells by activating JNK/c-Jun signaling

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Recent advances in the molecular basis of chemotherapy resistance and potential application of epigenetic therapeutics in chemorefractory renal cell carcinoma

Acharya, N., & Singh, K. P. (2022) · WIREs Mechanisms of Disease · doi:10.1002/wsbm.1575 · Cited by 11

Umbilical cord mesenchymal stem cells and breast cancer: a good therapeutic candidate or not? A minireview

Tavakoli, A., Kahrizi, M. S., Safa, K., Arefnezhad, R., & Rezaei‐Tazangi, F. (2022) · Molecular Biology Reports · doi:10.1007/s11033-022-07739-w · Cited by 9

Tumor Organoids: The Era of Personalized Medicine

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Patterning of supported lipid bilayers and proteins using material selective nitrodopamine-mPEG

Spycher, P. R., Hall, H., Viola Vogel, B., & Reimhult, E. (2014) · Biomaterials Science · doi:10.1039/c4bm00090k · Cited by 9

Phase I study of combined indomethacin and platinum-based chemotherapy to reduce platinum-induced fatty acids

Velden, D. L. V. D., Cirkel, G. A., Houthuijzen, J. M., van Werkhoven, E. D., Roodhart, J. M. L., Daenen, L. G. M., Kaing, S., Gerrits, J., Verhoeven‐Duif, N. M., Grootscholten, C., et al. (2018) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-018-3563-2 · Cited by 9

What Is the Storage Effect, Why Should It Occur in Cancers, and How Can It Inform Cancer Therapy?

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Tellurium compound provides pro-apoptotic signaling in drug resistant multiple myeloma

Zigman-Hoffman, E., Sredni, B., Meilik, B., Naparstek, E., & Tartakovsky, B. (2020) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428194.2020.1858292 · Cited by 9

KRAS mutant rectal cancer cells interact with surrounding fibroblasts to deplete the extracellular matrix

Kim, J. K., Marco, M. R., Choi, S., Qu, X., Chen, C., Elkabets, M., Fairchild, L., Chow, O. S., Barriga, F. M., Dow, L. E., et al. (2021) · Molecular Oncology · doi:10.1002/1878-0261.12960 · Cited by 10

Growth factor receptor and β1 integrin signaling differentially regulate basal clonogenicity and radiation survival of fibroblasts via a modulation of cell cycling

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Effective dose window for containing tumor burden under tolerable level

Masud, M. A., Kim, J., & Kim, E. (2023) · npj Systems Biology and Applications · doi:10.1038/s41540-023-00279-4 · Cited by 9

Animal models of extracranial pediatric solid tumors

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Non-catalytic region of tyrosine kinase adaptor protein 2 (NCK2) pathways as factor promoting aggressiveness in ovarian cancer

Fanelli, M., Camperchioli, A., Petrella, L., Petrillo, M., Baranello, C., Baccaro, P., Paolillo, C., Capoluongo, E., & Scambia, G. (2017) · The International Journal of Biological Markers · doi:10.5301/ijbm.5000264 · Cited by 9

Type I Collagen Aging Increases Expression and Activation of EGFR and Induces Resistance to Erlotinib in Lung Carcinoma in 3D Matrix Model

Sarazin, T., Collin, G., Buache, É., Gulick, L. V., Charpentier, C., Terryn, C., Morjani, H., & Saby, C. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.01593 · Cited by 9

Tracing Quiescent Cancer Cells In Vivo

Kim, M. J. (2024) · Cancers · doi:10.3390/cancers16223822 · Cited by 8

Global trends and research hotspots in nanodrug delivery systems for breast cancer therapy: a bibliometric analysis (2013–2023)

Li, Y., Liu, P., Zhang, B., Chen, J., & Yan, Y. (2025) · Discover Oncology · doi:10.1007/s12672-025-02014-3 · Cited by 10

Chemoresistance in Ovarian Cancer: The Role of Malignant Ascites

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Multiscale modeling of drug resistance in glioblastoma with gene mutations and angiogenesis

Yang, H., Lin, H., & Sun, X. (2023) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2023.10.037 · Cited by 8

Phosphorylation of IDH1 Facilitates Progestin Resistance in Endometrial Cancer

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A Review: Genetic Mutations as a Key to Unlocking Drug Resistance in Cervical Cancer

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The Research Progress of Metformin Regulation of Metabolic Reprogramming in Malignant Tumors

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Galectin-3 Release in the Bone Marrow Microenvironment Promotes Drug Resistance and Relapse in Acute Myeloid Leukemia

Yıldırım, C. (2025) · Life · doi:10.3390/life15060937 · Cited by 8

DNA damage response-initiated cytokine secretion in bone marrow stromal cells promotes chemoresistance of myeloma cells

Tang, H., Shu, M.-M., Dai, B., Xu, L., Dong, B., Gao, G., & Chen, X. (2017) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428194.2017.1413188 · Cited by 8

Enhanced expression of cyclooxygenase‐2 related multi‐drug resistance gene in melanoma and osteosarcoma cell lines by TSG‐6 secreted from canine adipose‐derived mesenchymal stem/stromal cells

Yang, S., An, J., Park, S., Lee, J., Chae, H., Lee, K., Song, W., & Youn, H. (2021) · Veterinary Medicine and Science · doi:10.1002/vms3.442 · Cited by 8

CRISPR-based knockout screening identifies the loss of MIEF2 to enhance oxaliplatin resistance in colorectal cancer through inhibiting the mitochondrial apoptosis pathway

Xie, C., Li, K., Li, Y., Peng, X., Teng, B., He, K., Jin, A., Wang, W., & Wei, Z. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.881487 · Cited by 8

The potential effects and mechanisms of Gegen Qinlian Decoction in oxaliplatin-resistant colorectal cancer based on network pharmacology

Lin, X., Xu, L., Tan, H., Zhang, X., Shao, H., Li, Y., & Huang, X. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e11305 · Cited by 8

Autocrine EGF and TGF ‐α promote primary and acquired resistance to ALK / c‐Met kinase inhibitors in non‐small‐cell lung cancer

Wang, Y., Zhang, Y., Chen, R., & Tian, X. (2022) · Pharmacology Research & Perspectives · doi:10.1002/prp2.1047 · Cited by 8

The Impact of Cell-Cell Contact, E-Cadherin and EGF Receptor on the Cellular Radiosensitivity of A431 Cancer Cells

Mazzeo, E., Hehlgans, S., Valentini, V., Baumann, M. A., & Cordes, N. (2012) · Radiation Research · doi:10.1667/rr2855.1 · Cited by 8

Liquid Overlay and Collagen-Based Three-Dimensional Models for In Vitro Investigation of Multiple Myeloma

Ilić, J., Koelbl, C., Simon, F., Wußmann, M., Ebert, R., Trivanović, D. I., & Herrmann, M. (2024) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2023.0374 · Cited by 8

Dissecting the Spatially Restricted Effects of Microenvironment-Mediated Resistance on Targeted Therapy Responses

Miti, T., Desai, B., Miroshnychenko, D., Basanta, D., & Marusyk, A. (2024) · Cancers · doi:10.3390/cancers16132405 · Cited by 7

Heterogeneity and therapeutic implications of cancer-associated fibroblasts in lung cancer: Recent advances and future perspectives

Yang, C., Liu, W., Powell, C. A., & Wang, Q. (2024) · Chinese Medical Journal - Pulmonary and Critical Care Medicine · doi:10.1016/j.pccm.2024.08.009 · Cited by 7

Cancer-Associated Fibroblast Heterogeneity Shapes Prognosis and Immune Landscapes in Head and Neck Squamous Cell Carcinoma

Takahashi, H., Hagiwara, H., Tada, H., Uchida, M., Matsuyama, T., & Chikamatsu, K. (2026) · Cancers · doi:10.3390/cancers18020215 · Cited by 7

Single-cell multi-omics for biomarker discovery: Technologies, molecular mechanisms, applications and translational challenges

Sahu, P., Satapathy, A., Satapathy, A., & Satapathy, T. (2025) · Letters in Drug Design & Discovery · doi:10.1016/j.lddd.2026.100286 · Cited by 7

Epigenetic regulation of radioresistance: insights from preclinical and clinical studies

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The Functional Transcriptomic Landscape Informs Therapeutic Strategies in Multiple Myeloma

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Recent development of nanotechnology-based approaches for gynecologic cancer therapy

Gedda, G., Park, Y.-J., & Pang, M. (2024) · Obstetrics & Gynecology Science · doi:10.5468/ogs.24180 · Cited by 7

Role of the Bone Marrow Microenvironment in Drug Resistance of Hematological Malignances

Hosseini, A., Hamblin, M. R., Mirzaei, H., & Mirzaei, H. R. (2021) · Current Medicinal Chemistry · doi:10.2174/0929867328666210910124319 · Cited by 7

Microvalve bioprinting as a biofabrication tool to decipher tumor and endothelial cell crosstalk: Application to a simplified glioblastoma model

Dusserre, N., Stachowicz, M., Medina, C. F., Henri, B., Fricain, J., Paris, F., & Oliveira, H. (2021) · Bioprinting · doi:10.1016/j.bprint.2021.e00178 · Cited by 7

Exploring MicroRNA and Exosome Involvement in Malignant Pleural Mesothelioma Drug Response

Johnson, B., Zhuang, L., Rath, E. M., Yuen, M. L., Cheng, N. C., Shi, H., Kao, S., Reid, G., & Cheng, Y. Y. (2022) · Cancers · doi:10.3390/cancers14194784 · Cited by 7

CircRNAs in Tumor Radioresistance

Gao, Y., Gao, J.-W., Lin, F., Wang, T., Huo, S. T., Wu, J., Zhou, Q., & Zhang, C. (2022) · Biomolecules · doi:10.3390/biom12111586 · Cited by 7

Rapid Extensive Recurrence of Triple Negative Breast Cancer: Are Both Therapy and Cancer Biology the Culprit?

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Pitch-tunable pillar arrays for high-throughput culture and immunohistological analysis of tumor spheroids

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Microphysiometry

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Investigating Cancerous Exosomes’ Effects on CD8+ T-Cell IL-2 Production in a 3D Unidirectional Flow Bioreactor Using 3D Printed, RGD-Functionalized PLLA Scaffolds

Karami, D., Srivastava, A., Ramesh, R., & Sikavitsas, V. I. (2022) · Journal of Functional Biomaterials · doi:10.3390/jfb13010030 · Cited by 7

The ability of hyaluronan fragments to reverse the resistance of C6 rat glioma cell line to temozolomide and carmustine

Karbownik, M. S., Pietras, T., Szemraj, J., Kowalczyk, E., & Nowak, J. Z. (2014) · Współczesna Onkologia · doi:10.5114/wo.2014.43493 · Cited by 7

Silencing GnT‑V reduces oxaliplatin chemosensitivity in human colorectal cancer cells through N‑glycan alteration of organic cation transporter member 2

Cong, X., Liu, X., Dong, X., Fang, S., Sun, Z., & Fan, J. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.9560 · Cited by 6

Thrombospondin-1 Receptor CD47 Overexpression Contributes to P-Glycoprotein-Mediated Multidrug Resistance Against Doxorubicin in Thyroid Carcinoma FTC-133 Cells

Courageot, M.-P., Duca, L., Martiny, L., Devarenne-Charpentier, E., Morjani, H., & Btaouri, H. E. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.551228 · Cited by 6

Immune modulatory effects of Idelalisib in stromal cells of chronic lymphocytic leukemia

Handl, S., von Heydebrand, F., Völkl, S., Oostendorp, R. A. J., Wilke, J., Kremer, A. N., Mackensen, A., & Lutzny‐Geier, G. (2021) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428194.2021.1927019 · Cited by 7

Receptor Activator of NF-κB (RANK) Confers Resistance to Chemotherapy in AML and Associates with Dismal Disease Course

Clar, K. L., Weber, L. M., Schmied, B. J., Heitmann, J. S., Marconato, M., Tandler, C., Schneider, P., & Salih, H. R. (2021) · Cancers · doi:10.3390/cancers13236122 · Cited by 6

Exostosin 1 Knockdown Induces Chemoresistance in MV3 Melanoma Cells by Upregulating JNK and MEK/ERK Signaling

Pfeifer, V., Weber, H., Wang, Y., Schlesinger, M., Gorzelanny, C., & Bendas, G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065452 · Cited by 6

P53‑microRNA interactions regulate the response of colorectal tumor cells to oxaliplatin under normoxic and hypoxic conditions

Zhang, J., Li, C., Sun, L., Sun, D., & Zhao, T. (2023) · Oncology Reports · doi:10.3892/or.2023.8656 · Cited by 6

Cancer stem cells, their origin and niche: A search for the therapeutic target

Das, A., Dutta, A., Paul, S., Dutta, A., Bhattacharya, A., Banerjee, S., Chowdhury, D. D., Basak, U., Khan, P., Mazumdar, D., et al. (2017) · Journal of Stem Cell Research and Medicine · doi:10.15761/jscrm.1000118 · Cited by 6

Associations of novel serum lipid index with epithelial ovarian cancer chemoresistance and prognosis

Li, Y., Shang, C., Liang, H., Zhang, K., Wu, Y., & Guo, H. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1052760 · Cited by 6

XBP1-LOX Axis is critical in ER stress-induced growth of lung adenocarcinoma in 3D culture.

Yang, Y., Cheng, B.-J., Jian, H., Chen, Z., Zhao, Y., Yu, Y., Li, Z., Liao, M., & Lu, S. (2017) · Europe PMC (PubMed Central) · Cited by 6

Tumor stroma as contributing factor in the lymph node metastases process?

Mesker, W. E., van Pelt, G. W., & Tollenaar, R. A. �. �. (2019) · Oncotarget · doi:10.18632/oncotarget.26644 · Cited by 6

Integrins and Cell Metabolism: An Intimate Relationship Impacting Cancer

Ata, R., & Antonescu, C. N. (2021) · doi:10.32920/14639496.v1 · Cited by 6

Risk score constructed with neutrophil extracellular traps-related genes predicts prognosis and immune microenvironment in multiple myeloma

Gao, G., Liu, R., Dong, W., Gao, D., Lv, Y., Xu, X., Fu, B., Lin, Z., Wang, T., He, A., et al. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1365460 · Cited by 5

3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline

Yang, X., Artibani, M., Jin, Y., Aggarwal, A., Zhang, Y., Muñoz-Galván, S., Mikhailova, E., Rai, L. J., Mukherjee, N., Kumar, R. K., et al. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202404072 · Cited by 5

Heparanase-Inhibiting Polymeric Heparan Sulfate Mimetic Attenuates Myeloma Tumor Growth and Bone Metastasis

Singh, K., Tapayan, A. S., Sletten, E. T., Loka, R. S., Barash, U., Vlodavsky, I., & Nguyen, H. M. (2025) · ACS Applied Bio Materials · doi:10.1021/acsabm.5c00771 · Cited by 5

An oxidized dextran and thiolated chitosan-based hydrogel driven biomimetic triple negative breast cancer 3D in vitro model for cancer progression and therapeutic studies

Modi, U., Makwana, P., Dhimmar, B., Ramu, S., Jolly, M. K., & Vasita, R. (2025) · Journal of Materials Chemistry B · doi:10.1039/d5tb00812c · Cited by 5

Choosing the right animal model for sarcoma research

Remiszewski, P., Siedlecki, E., Wełniak-Kamińska, M., Mikula, M., & Czarnecka, A. M. (2026) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-025-06013-z · Cited by 5

Prognostic value of serum lipids in newly diagnosed acute promyelocytic leukemia

Wang, S., Wang, Q., Lv, S., & Qin, L. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1522239 · Cited by 5

Diagnostic and Therapeutic Applications of Exosome Nanovesicles in Lung Cancer: State-of-The-Art

Sahebkar, A., Mohammadi, R., Hosseini, S. A., Noruzi, S., & Ebrahimzadeh, A. (2021) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/1871520621666210301085318 · Cited by 5

Biosynthetic exosome nanoparticles isolation, characterization, and their diagnostic and therapeutic applications

Anand, K., Chandrasekaran, B., Gupta, G., Dureja, H., Singh, S. K., Gulati, M., Chellappan, D. K., Balasubramanian, B., Femeela, I., Arumugam, V. A., et al. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85503-7.00037-7 · Cited by 5

IRE1a-Induced FilaminA Phosphorylation Enhances Migration of Mesenchymal Stem Cells Derived from Multiple Myeloma Patients

Da Ros, F., Kowal, K., Vicinanza, C., Lombardi, E., Agostini, F., Ciancia, R., Rupolo, M., Durante, C., Michieli, M., & Mazzucato, M. (2023) · Cells · doi:10.3390/cells12151935 · Cited by 5

Integrin alphaV modulates the cellular pharmacology of copper and cisplatin by regulating expression of the influx transporter CTR1

Lin, X., Shang, X., Manorek, G., Fofana, M., & Howell, S. B. (2014) · Oncoscience · doi:10.18632/oncoscience.22 · Cited by 5

Role of MSCs in Antitumor Drug Resistance

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