Senescence in tumours: evidence from mice and humans

Cited by (1,000)

Items 401–500 of 1,000

1. Caveolin-1 promotes the tumor suppressor properties of oncogene-induced cellular senescence
   Daniela Volonté, Avani R. Vyas, Chen Chen, Sanja Đačić, Laura P. Stabile, Brenda F. Kurland, Shira R. Abberbock, Timothy Francis Burns, James Gordon Herman, Y. Peter Di et al. · 2017 · Journal of Biological Chemistry
2. Nuclear receptors: Lipid and hormone sensors with essential roles in the control of cancer development
   Joan Font-Díaz, Alba Jiménez‐Panizo, Carmé Caelles, María dM Vivanco, Paloma Pérez, Ana Aranda, Eva Estébanez‐Perpiñá, Antonio Castrillo, Mercedes Ricote, Annabel F. Valledor · 2020 · Seminars in Cancer Biology
3. PTEN deletion in luminal cells of mature prostate induces replication stress and senescence in vivo
   Parisotto, Maxime, Grelet, Elise, El Bizri, Rana, Dai, Yongyuan, Terzic, Julie, Eckert, Doriane, Gargowitsch, Laetitia, Bornert, Jean-Marc, Metzger, Daniel · 2018 · Journal of Experimental Medicine
4. RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness
   Benítez, Sandra, Cordero, Alex, Santamaría, Patricia G., Redondo-Pedraza, Jaime, Rocha, Ana S., Collado-Solé, Alejandro, Jimenez, Maria, Sanz-Moreno, Adrian, Yoldi, Guillermo, Santos, Juliana C. et al. · 2021 · Developmental Cell
5. Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars
   Ricardo Iván Martínez‐Zamudio, Alketa Stefa, José Américo Nabuco Leva Ferreira de Freitas, Themistoklis Vasilopoulos, Mark Simpson, Grégory R G Doré, Pierre‐François Roux, Mark A. Galan, Ravi J. Chokshi, Oliver Bischof et al. · 2023 · Cell Genomics
6. How to become immortal: let MEFs count the ways
   Adam F. Odell, Jon M. Askham, Catherine Whibley, Monica Hollstein · 2010 · Aging
7. Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer
   Kanchan Singh, Melissa A. Pruski, Rachael Bland, Mamoun Younes, Sushovan Guha, Nirav C Thosani, Anirban Maitra, Brooks D. Cash, Florencia M. McAllister, Craig D. Logsdon et al. · 2020 · Laboratory Investigation
8. How Does Endometriosis Lead to Ovarian Cancer? The Molecular Mechanism of Endometriosis-Associated Ovarian Cancer Development
   Nozomi Yachida, Kosuke Yoshihara, Manako Yamaguchi, Kazuaki Suda, Ryo Tamura, Takayuki Enomoto · 2021 · Cancers
9. Metabolic alterations accompanying oncogene-induced senescence
   Aird, Katherine M, Zhang, Rugang · 2014 · Molecular & Cellular Oncology
10. The mechanism of dysbiosis in alcoholic liver disease leading to liver cancer
    Nahum M�ndez-S�nchez, Alejandro Valencia-Rodríguez, Alfonso Vera-Barajas, Ludovico Abenavoli, Emidio Scarpellini, Guadalupe Ponciano Rodríguez · 2020 · Hepatoma Research
11. Nuclear receptor HNF4α performs a tumor suppressor function in prostate cancer via its induction of p21-driven cellular senescence
    Zhu Wang, Youjia Li, Dinglan Wu, Shan Yu, Yuliang Wang, Franky Leung Chan · 2019 · Oncogene
12. Age-Related Changes in the Fibroblastic Differon of the Dermis: Role in Skin Aging
    A. I Zorina, V. L Zorin, Dmitry Anatolievich Kudlay, Pavel Kopnin · 2022 · International Journal of Molecular Sciences
13. Heparan sulfation is essential for the prevention of cellular senescence
    Seung Hee Jung, H C Lee, D-M Yu, Bong‐Cho Kim, S M Park, Yerin Lee, H. J. Park, Y-G Ko, J-S Lee · 2015 · Cell Death and Differentiation
14. RRM2B Suppresses Activation of the Oxidative Stress Pathway and is Up-regulated by P53 During Senescence
    Mei-Ling Kuo, Alexander J. Sy, Lijun Xue, Martin Chi, Michelle T. -C. Lee, Terence Yen, Mei-Iok Chiang, Lufen Chang, Peiguo G. Chu, Yun Yen · 2012 · Scientific Reports
15. The development of cell senescence.
    Da Silva-Álvarez, Sabela, Picallos-Rabina, Pilar, Antelo-Iglesias, Lucía, Triana-Martínez, Francisco, Barreiro-Iglesias, Antón, Sánchez, Laura, Collado, Manuel · 2019 · Experimental Gerontology
16. Polo‐like kinase 4 inhibitor CFI‐400945 suppresses liver cancer through cell cycle perturbation and eliciting antitumor immunity
    Cerise Yuen‐Ki Chan, Vincent Wai‐Hin Yuen, David Kung‐Chun Chiu, Chi‐Ching Goh, Kelsie L. Thu, David W. Cescon, Isabel Soria‐Bretones, Cheuk‐Ting Law, Jacinth Wing‐Sum Cheu, Derek Lee et al. · 2022 · Hepatology
17. Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth
    David Vindrieux, Guillaume Devailly, Arnaud Augert, Benjamin Le Calvé, Mylène Ferrand, Pascal Pigny, Lea Francoise Payen, Gerard J. Lambeau, Michaël Perrais, Sébastien Aubert et al. · 2014 · Oncotarget
18. SIRT1 Inactivation Evokes Antitumor Activities in NSCLC through the Tumor Suppressor p27
    Lijia Zhu, Christine Chiao, Katelyn G. Enzer, Alexander J. Stankiewicz, Douglas V. Faller, Yan Dai · 2014 · Molecular Cancer Research
19. Alterations in Ca2+ Signalling via ER-Mitochondria Contact Site Remodelling in Cancer
    Martijn Kerkhofs, Carlotta Giorgi, Saverio Marchi, Bruno Seitaj, Jan B. Parys, Paolo Pinton, Geert Bultynck, Mart Bittremieux · 2017 · Advances in experimental medicine and biology
20. The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma
    Lennart Lenk, Maren Pein, Olga Will, Beatriz Aguilar Gomez, Fabrice Viol, Charlotte Hauser, Jan‐Hendrik Egberts, Jan-Paul Gundlach, Ole Helm, Sanjay Tiwari et al. · 2017 · OncoImmunology
21. Cellular senescence: from anti-cancer weapon to anti-aging target
    Lifeng Yuan, Peter B. Alexander, Xiao‐Fan Wang · 2020 · Science China Life Sciences
22. Redd1 knockdown prevents doxorubicin-induced cardiac senescence
    Pianpian Huang, Lijuan Bai, Lihua Liu, Jun Fen Fu, Kefei Wu, Hongxia Liu, Yun Liu, Benming Qi, Benling Qi · 2021 · Aging
23. Activatable senoprobes and senolytics: Novel strategies to detect and target senescent cells
    Samir Morsli, Gary Joseph Doherty, Daniel Muñoz‐Espín · 2022 · Mechanisms of Ageing and Development
24. Neutrophils: Critical components in experimental animal models of cancer
    Catharina Hagerling, Zena Werb · 2016 · Seminars in Immunology
25. ZRF1 controls oncogene-induced senescence through the INK4-ARF locus
    Ribeiro, J D, Morey, L, Mas, A, Gutierrez, A, Luis, N M, Mejetta, S, Richly, H, Benitah, S A, Keyes, W M, Di Croce, L · 2013 · Oncogene
26. Insights from In Vivo Studies of Cellular Senescence
    Prieto, Luis I., Graves, Sara I., Baker, Darren J. · 2020 · Cells
27. Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence
    Jimin Shin, Jiwon Yang, Jang Choon Lee, Kwan‐Hyuck Baek · 2013 · Cellular Signalling
28. Mitotic slippage and the subsequent cell fates after inhibition of Aurora B during tubulin-binding agent–induced mitotic arrest
    Yasuo Tsuda, Makoto Iimori, Yuichiro Nakashima, Ryota Nakanishi, Koji Ando, Kippei Ohgaki, Hiroyuki Kitao, Hiroshi Saeki, Eiji Oki, Yoshihiko Maehara · 2017 · Scientific Reports
29. The Achilles’ heel of cancer survivors: fundamentals of accelerated cellular senescence
    Shameel Shafqat, Evelyn Arana‐Chicas, Areez Shafqat, Shahrukh Khurshid Hashmi · 2022 · Journal of Clinical Investigation
30. Accelerated cellular senescence phenotype of GAPDH-depleted human lung carcinoma cells
    Manali A. Phadke, Natalia F. Krynetskaia, Anurag Mishra, Evgeny Y. Krynetskiy · 2011 · Biochemical and Biophysical Research Communications
31. Senescence, NK cells, and cancer: navigating the crossroads of aging and disease
    Marina Gergues, Rafijul Bari, Sharmila Koppisetti, Anna Gosiewska, Lin Kang, ROBERT J. HARIRI · 2025 · Frontiers in Immunology
32. Dexamethasone Reduces Sensitivity to Cisplatin by Blunting p53-Dependent Cellular Senescence in Non-Small Cell Lung Cancer
    Haiyan Ge, Songshi Ni, Xingan Wang, Nuo Xu, Ying Min Liu, Xun Wang, Lingyan Wang, Dongli Song, Yuanlin Song, Chunxue Bai · 2012 · PLoS ONE
33. Immunosurveillance of senescent cancer cells by natural killer cells
    Alexandre Iannello, David H. Raulet · 2014 · OncoImmunology
34. Therapy-Induced Stromal Senescence Promoting Aggressiveness of Prostate and Ovarian Cancer
    Elisa Pardella, Erica Pranzini, Ilaria Nesi, Matteo Parri, Pietro Spatafora, Eugenio Torre, Angela Muccilli, Francesca Castiglione, Massimiliano Fambrini, Flavia Sorbi et al. · 2022 · Cells
35. Immunometabolism and oxidative stress: roles and therapeutic strategies in cancer and aging
    Nan-jie Zhou, Wei-Qian Bao, Cuifen Zhang, Menglin Jiang, Tu-Liang Liang, Gang-Yuan Ma, Liang Liu, Hudan Pan, Run-Ze Li · 2025 · npj Aging
36. Regulation of senescence by microRNA biogenesis factors
    Kotb Abdelmohsen, Subramanya Srikantan, Min Ju Kang, Myriam Gorospe · 2012 · Ageing Research Reviews
37. Jumonji domain-containing protein 2B silencing induces DNA damage response via STAT3 pathway in colorectal cancer
    L Chen, Lin Na Fu, X Kong, Jing Xu, Z Wang, Xiong Ma, Yoshimitsu Akiyama, Yongjun Chen, Jing‐Yuan Fang · 2014 · British Journal of Cancer
38. IKKα inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways
    Na‐Young Song, Feng Zhu, Zining Wang, Jami Willette‐Brown, Sichuan Xi, Zhonghe Sun, Ling Su, Xiaolin Wu, Buyong Ma, Ruth Nussinov et al. · 2018 · Proceedings of the National Academy of Sciences
39. Cytotoxicity and cell death mechanisms induced by the polyamine-vectorized anti-cancer drug F14512 targeting topoisomerase II
    Viviane Brel, Jean‐Philippe Annereau, Stéphane Vispé, Anna Kruczynski, Christian Bailly, Nicolas Guilbaud · 2011 · Biochemical Pharmacology
40. Are aging biomarkers clinically relevant in oncogeriatrics?
    Claire Falandry, Éric Gilson, K. Lenhard Rudolph · 2012 · Critical Reviews in Oncology/Hematology
41. Shifting senescence into quiescence by turning up p53
    Manuel Serrano · 2010 · Cell Cycle
42. Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma
    Caroline E. Gleason, Mark Andrew Dickson, Mary E. Klein, Cristina R. Antonescu, Rodrigo Gularte‐Mérida, Marimar Benitez, Juliana I. Delgado, Raghu P. Kataru, Mark Wei Yi Tan, Martina Bradić et al. · 2023 · Clinical Cancer Research
43. Senescent skeletal muscle fibroadipogenic progenitors recruit and promote M2 polarization of macrophages
    Xu Zhang, Yan Er Ng, L Chini, Amanda A. Heeren, Thomas A. White, Hao Li, Haojie Huang, Madison L. Doolittle, Sundeep Khosla, Nathan K. LeBrasseur · 2023 · Aging Cell
44. Identification of miR‐494 direct targets involved in senescence of human diploid fibroblasts
    Marika Comegna, Mariangela Succoio, Marco A. Napolitano, Monica Vitale, Chiara DˈAmbrosio, Andrea Scaloni, Fabiana Passaro, Nicola Zambrano, Filiberto Cimino, Raffaella Faraonio · 2014 · The FASEB Journal
45. Molecular mechanism of Forkhead box M1 inhibition by thiostrepton in breast cancer cells
    Mesayamas Kongsema, Sudtirak Wongkhieo, Mattaka Khongkow, Eric W.‐F. Lam, Phansiri Boonnoy, Wanwipa Vongsangnak, Jirasak Wong-ekkabut · 2019 · Oncology Reports
46. Glioblastoma-initiating cell heterogeneity generated by the cell-of-origin, genetic/epigenetic mutation and microenvironment
    Tôru Kondo · 2021 · Seminars in Cancer Biology
47. Expression of therapy-induced senescence markers in breast cancer samples upon incomplete response to neoadjuvant chemotherapy
    Tareq Saleh, Ahmad Alhesa, Mahmoud Al-Balas, Omar M. Abuelaish, Ahmad T. Mansour, Heyam Awad, Mohammed El‐Sadoni, Valerie J. Carpenter, Belal Azab · 2021 · Bioscience Reports
48. The tumor suppressor ING1b is a novel corepressor for the androgen receptor and induces cellular senescence in prostate cancer cells
    Mohsen Esmaeili, Susanne Jennek, Susann Ludwig, Alexandra Klitzsch, Florian Kraft, Christian Melle, Aria Baniahmad · 2016 · Journal of Molecular Cell Biology
49. Different Roles of Negative and Positive Components of the Circadian Clock in Oncogene-induced Neoplastic Transformation
    Chiharu Katamune, Satoru Koyanagi, Shoya Shiromizu, Naoya Matsunaga, Shigeki Shimba, Shigenobu Shibata, Shigehiro Ohdo · 2016 · Journal of Biological Chemistry
50. The impact of ageing mechanisms on musculoskeletal system diseases in the elderly
    Yijin Cai, Zhongyu Han, Hong Cheng, Hongpeng Li, Ke Wang, Jia Chen, Zhixiang Liu, Yu‐Long Xie, Yumeng Lin, Shuwei Zhou et al. · 2024 · Frontiers in Immunology
51. Sprouty1 is a candidate tumor-suppressor gene in medullary thyroid carcinoma
    Anna Macià, Pilar Gallel, Marta Vaquero, Myriam Gou-Fàbregas, Marı́a Santacana, Agnieszka Maliszewska, Mercedes Robledo, Jennifer R. Gardiner, M. Albert Basson, Xavier Matías‐Guiu et al. · 2011 · Oncogene
52. Vav1 Fine Tunes p53 Control of Apoptosis versus Proliferation in Breast Cancer
    Shulamit Sebban, Marganit Farago, Dan Gashai, Lena Ilan, Eli Pikarsky, Ittai Ben‐Porath, Shulamit Katzav · 2013 · PLoS ONE
53. Myc, Cdk2 and cellular senescence: Old players, new game
    Stefano Campaner, Mirko Doni, Alessandro Verrecchia, Giovanni Fagà, Lucia Bianchi, Bruno B. Amati · 2010 · Cell Cycle
54. Shp2 signaling suppresses senescence in PyMT‐induced mammary gland cancer in mice
    Linxiang Lan, Jane D. Holland, Jingjing Qi, Stefanie Grosskopf, Regina Vogel, Balázs Győrffy, Annika Wulf‐Goldenberg, Walter Birchmeier · 2015 · The EMBO Journal
55. Cisplatin induces cell cycle arrest and senescence via upregulating P53 and P21 expression in HepG2 cells.
    Kai Qu, Ting Yu Lin, Jichao Wei, Fandi Meng, Zhixin Wang, Zichao Huang, Yong Wan, Sidong Song, Sinan Liu, Hulin Chang et al. · 2013 · PubMed
56. Luotonin-A based quinazolinones cause apoptosis and senescence via HDAC inhibition and activation of tumor suppressor proteins in HeLa cells
    Ramineni Venkatesh, Mekala Janaki Ramaiah, Hanmant K. Gaikwad, Sridhara Janardhan, Rajashaker Bantu, Lingaiah Nagarapu, Garikapati Narahari Sastry, Raksha A. Ganesh, Manikapal Bhadra · 2015 · European Journal of Medicinal Chemistry
57. TRADD contributes to tumour suppression by regulating ULF-dependent p19Arf ubiquitylation
    Iok In Christine Chio, Masato Sasaki, Danny Ghazarian, Juan Carlos Alvarez Moreno, Susan J. Done, Takeshi Ueda, Satoshi Inoue, Yu‐Ling Chang, Nien‐Jung Chen, Tak W. Mak · 2012 · Nature Cell Biology
58. EpCAM overexpression prolongs proliferative capacity of primary human breast epithelial cells and supports hyperplastic growth
    Agnieszka Martowicz, Johannes Rainer, Julien Lelong, Gilbert Spizzo, Guenther A. Gastl, Gerold Untergasser · 2013 · Molecular Cancer
59. Molecular Pathways: Harnessing E2F1 Regulation for Prosenescence Therapy in p53-Defective Cancer Cells
    Anni Laine, Jukka K. Westermarck · 2014 · Clinical Cancer Research
60. Ageing, cellular senescence and the impact of diet: an overview
    Ana Isabel Maduro, Carla Luís, Raquel A. Soares · 2021 · Porto Biomedical Journal
61. Gynecologic Cancer, Cancer Stem Cells, and Possible Targeted Therapies
    Vahideh Keyvani, Espanta Riahi, Meysam Yousefi, Seyed‐Alireza Esmaeili, Rana Shafabakhsh, Amin Moradi Hasan‐Abad, Maryam Mahjoubin‐Tehran, Michael Richard Hamblin, Samaneh Mollazadeh, Hamed Mirzaei · 2022 · Frontiers in Pharmacology
62. A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest
    Steven P. Angus, Joseph R. Nevins · 2012 · Oncogene
63. The human oncoprotein MDM2 induces replication stress eliciting early intra-S-phase checkpoint response and inhibition of DNA replication origin firing
    Rebecca A. Frum, Sandeep K. Singh, Catherine A. Vaughan, Nitai D. Mukhopadhyay, S. R. Grossman, Bradford E. Windle, Sumitra Deb, Sumitra Deb · 2013 · Nucleic Acids Research
64. Contribution of viral and bacterial infections to senescence and immunosenescence
    Antonia Reyes, Gerardo Ortiz, Luisa Fernanda Duarte, Christian Fernández, Rosario Hernández‐Armengol, Pablo A. Palacios, Yolanda Prado, Catalina A. Andrade, Linmar Rodríguez‐Guilarte, Alexis M. Kalergis et al. · 2023 · Frontiers in Cellular and Infection Microbiology
65. Promising new drugs and therapeutic approaches for treatment of ovarian cancer—targeting the hallmarks of cancer
    Julia S. Hillmann, Nicolaì Maass, Dirk Bauerschlag, Inken Flörkemeier · 2025 · BMC Medicine
66. The SCN 9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway
    Marine Warnier, Jean‐Michel Flaman, Christophe Chouabe, Clotilde Wiel, Baptiste Gras, Audrey Griveau, Elena Blanc, Jean‐Philippe Foy, Pauline Mathot, Pierre Saintigny et al. · 2018 · Aging Cell
67. Oncodriver inhibition and CD4+ Th1 cytokines cooperate through Stat1 activation to induce tumor senescence and apoptosis in HER2+ and triple negative breast cancer: implications for combining immune and targeted therapies
    Cinthia Rosemblit, Jashodeep Datta, Lea Lowenfeld, Shuwen Xu, Amrita B Basu, Krithika Nandakumar Kodumudi, Doris A. Wiener, Brian J. Czerniecki · 2018 · Oncotarget
68. Hypoxia negatively affects senescence in osteoclasts and delays osteoclastogenesis
    B. M. C. Gorissen, Alain de Bruin, Alberto Miranda Bedate, Nicoline M. Korthagen, Claudia F. Wolschrijn, Teun J. de Vries, P. René van Weeren, Marianna A. Tryfonidou · 2018 · Journal of Cellular Physiology
69. Bone Marrow Senescence and the Microenvironment of Hematological Malignancies
    Charlotte Hellmich, Jamie A Moore, Kristian M. Bowles, Stuart A. Rushworth · 2020 · Frontiers in Oncology
70. From Development to Aging: The Path to Cellular Senescence
    Alessandra Sacco, Laura Belloni, Lucia Latella · 2020 · Antioxidants and Redox Signaling
71. Age influences structural brain restoration during weight gain therapy in anorexia nervosa
    Lisa‐Katrin Kaufmann, Jürgen Hänggi, Lutz Jäncke, Volker Baur, Marco Piccirelli, Spyros Kollias, Ulrich Schnyder, Chantal Martin-Söelch, Gabriella Franca Milos · 2020 · Translational Psychiatry
72. Thyroid hormone and thyroid hormone nuclear receptors: History and present state of art
    Július Brtko · 2021 · Endocrine Regulations
73. The Biology of Aging and Lymphoma: a Complex Interplay
    Clémentine Sarkozy, Gilles Andre Salles, Claire Falandry · 2015 · Current Oncology Reports
74. MicroRNAs Regulate Key Effector Pathways of Senescence
    Andrea Feliciano, Beatriz Sánchez‐Sendra, Hiroshi Kondoh, Matilde Esther LLeonart · 2011 · Journal of Aging Research
75. Cellular Senescence in the Treatment of Ovarian Cancer
    Zehua Wang, Haiou Liu, Congjian Xu · 2018 · International Journal of Gynecological Cancer
76. Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest
    Noa Aharon-Hefetz, Idan Frumkin, Yoav Mayshar, Orna Dahan, Yitzhak Pilpel, Roni Rak · 2020 · eLife
77. Role of Complement in Regulating Inflammation Processes in Renal and Prostate Cancers
    Giuseppe Stefano Netti, Rossana Franzin, Alessandra Stasi, Federica Spadaccino, Andrea Dello Strologo, Barbara Infante, Loreto Gesualdo, Giuseppe Castellano, Elena Ranieri, Giovanni Stallone · 2021 · Cells
78. Cancer of unknown primary (CUP): does cause of death and family history implicate hidden phenotypically changed primaries?
    Kari Hemminki, Melanie Bevier, Jan Sundquist, Akseli Hemminki · 2012 · Annals of Oncology
79. The tumor suppressor ING1 contributes to epigenetic control of cellular senescence
    María Abad, Alberto Moreno, Alicia Palacios, Masako Narita, Francisco J. Blanco, Gema Moreno‐Bueno, Masashi Narita, Ignacio Palmero · 2010 · Aging Cell
80. Methods for the discovery of new anti-aging products – targeted approaches
    Azadeh Manayi, Soodabeh Saeidnia, Ahmad Reza Gohari, Mohammad Reza Abdollahi · 2014 · Expert Opinion on Drug Discovery
81. The PPARγ‐SETD8 axis constitutes an epigenetic, p53‐independent checkpoint on p21‐mediated cellular senescence
    Chieh‐Tien Shih, Ian Yi‐Feng Chang, Yi‐Tung Chen, Chung‐Pei Ma, Hui‐Wen Chen, Chang‐Ching Yang, Juu‐Chin Lu, Yau-Sheng Tsai, Hua‐Chien Chen, Bertrand Chin‐Ming Tan · 2017 · Aging Cell
82. The Molecular Chaperone Heat Shock Protein 70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA Damage and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Signaling Pathways
    Wonkyoung Cho, Xiongjie Jin, Junfeng Pang, Yan Wang, Nahid F. Mivechi, Demetrius Moskophidis · 2019 · Molecular and Cellular Biology
83. Insights Into Mechanisms of Tumor and Immune System Interaction: Association With Wound Healing
    А. V. Ponomarev, Irina Zh. Shubina · 2019 · Frontiers in Oncology
84. Biomechanics of T Cell Dysfunctions in Chronic Diseases
    Sachith D. Gunasinghe, Newton G. Peres, Jesse Goyette, Katharina Gaus · 2021 · Frontiers in Immunology
85. Transformation Assay in Bhas 42 Cells: A Model Using Initiated Cells to Study Mechanisms of Carcinogenesis and Predict Carcinogenic Potential of Chemicals
    Kiyoshi Sasaki, Makoto Umeda, Ayako Sakai, Shojiro Yamazaki, Noriho Tanaka · 2015 · Journal of Environmental Science and Health Part C
86. CDK2 Transcriptional Repression Is an Essential Effector in p53-Dependent Cellular Senescence—Implications for Therapeutic Intervention
    Hasan Zalzali, Bilal Nasr, Mohamad Harajly, Hussein Basma, Farah Ghamloush, Sandra E. Ghayad, Noël Ghanem, Gérard I. Evan, Raya Hamad Saab · 2014 · Molecular Cancer Research
87. Therapy-induced microenvironmental changes in cancer
    Yuting Ma, Heng Yang, Jonathan M. Pitt, Guido Kroemer, Laurence Zitvogel · 2016 · Journal of Molecular Medicine
88. ASPL-TFE3 Oncoprotein Regulates Cell Cycle Progression and Induces Cellular Senescence by Up-Regulating p21
    Naoko Ishiguro, Haruhiko Yoshida · 2016 · Neoplasia
89. The secretory phenotype of senescent astrocytes isolated from Wistar newborn rats changes with anti-inflammatory drugs, but does not have a short-term effect on neuronal mitochondrial potential
    Luis Ángel Maciel-Barón, Sandra Lizbeth Morales-Rosales, Alejandro Silva‐Palacios, Roxana Rodríguez‐Barrera, Jorge A. García, Armando Luna‐López, Viviana Pérez, Claudio A. Torres, Mina Königsberg · 2018 · Biogerontology
90. Cellular senescence in glioma
    Rafał Chojak, Jawad Fares, Edgar Petrosyan, Maciej S. Lesniak · 2023 · Journal of Neuro-Oncology
91. Reversion-inducing cysteine-rich protein with Kazal motifs interferes with epidermal growth factor receptor signaling
    Shunsuke Kitajima, Takao Miki, Yujiro Takegami, Yukiharu Kido, Makoto Noda, Eiji Hara, Awad Shamma, Chiaki Takahashi · 2010 · Oncogene
92. Sprouty1 induces a senescence-associated secretory phenotype by regulating NFκB activity: implications for tumorigenesis
    Anna Macià, Marta Vaquero, Myriam Gou-Fàbregas, Esmeralda Castelblanco, José Manuel Valdivielso, Carlos Anerillas, Dı́dac Mauricio, Xavier Matías‐Guiu, Joan Ribera, Mario Encinas · 2013 · Cell Death and Differentiation
93. Impaired JNK Signaling Cooperates with KrasG12D Expression to Accelerate Pancreatic Ductal Adenocarcinoma
    Clare C. Davies, Emma Harvey, R F McMahon, Katherine G. Finegan, Frances Connor, Roger J. Davis, David Arthur Tuveson, Cathy Tournier · 2014 · Cancer Research
94. Inactivation of Heat Shock Factor Hsf4 Induces Cellular Senescence and Suppresses Tumorigenesis In Vivo
    Xiongjie Jin, Binnur Eroglu, Wonkyoung Cho, Yukihiro Yamaguchi, Demetrius Moskophidis, Nahid F. Mivechi · 2012 · Molecular Cancer Research
95. Functional gene expression profile underlying methotrexate-induced senescence in human colon cancer cells
    Magdalena Dąbrowska, Marek Skoneczny, Wojciech Rode · 2011 · Tumor Biology
96. Functional and structural insights into RAS effector proteins
    Alessandro Mauro Mozzarelli, Dhirendra K. Simanshu, Pau Castel · 2024 · Molecular Cell
97. Inflammation to cancer: The molecular biology in the pancreas (Review)
    Sunbin Ling, Tingting Feng, Kaiqi Jia, Yu Tian, YAN LI · 2014 · Oncology Letters
98. Primordial Dwarfism Gene Maintains Lin28 Expression to Safeguard Embryonic Stem Cells from Premature Differentiation
    Qian Dai, Guangxin Luan, Li Deng, Tingjun Lei, Han Chang Kang, Xu Song, Yujun Zhang, Zhi‐Xiong Jim Xiao, Qintong Li · 2014 · Cell Reports
99. Mechanisms of oncogene-induced genomic instability
    Simona Graziano, Susana Gonzalo · 2016 · Biophysical Chemistry
100. PTEN loss and activation of K‐RAS and β‐catenin cooperate to accelerate prostate tumourigenesis
     Matthew T Jefferies, Adam C Cox, Boris Y. Shorning, Valérie S. Méniel, David F R Griffiths, Howard Kynaston, Matthew John Smalley, Alan Richard Clarke · 2017 · The Journal of Pathology