Senescence in tumours: evidence from mice and humans
DOI 10.1038/nrc2772
Cited by (1,000)
Items 501–600 of 1,000
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- Circadian clock protein CRY1 prevents paclitaxel‑induced senescence of bladder cancer cells by promoting p53 degradationMin Jia, Bijia Su, Lijun Mo, Wen Qiu, Jiaxu Ying, Lin Peng, Bingxuan Yang, Danying Li, Dongxia Wang, Lili Xu et al. · 2020 · Oncology Reports
- Promises and challenges of senolytics in skin regeneration, pathology and ageingVera Pils, Nadja Ring, Karla Valdivieso, Ingo Lämmermann, Флориан Грубер, Markus Schosserer, Johannes Grillari, Mikolaj B. Ogrodnik · 2021 · Mechanisms of Ageing and Development
- A lower bar for senescenceManuel Serrano · 2010 · Nature
- DUSP 16 ablation arrests the cell cycle and induces cellular senescenceHaibin Zhang, Hai Zheng, Wenjing Mu, Zhiying He, Bo Yang, Yuan Ji, Lijian Hui · 2015 · FEBS Journal
- Oncogenic KRAS activates an embryonic stem cell-like program in human colon cancer initiationAnne-France Le Rolle, Thang Kien Chiu, Zhaoshi Zeng, Jinru Shia, Martin R. Weiser, Philip B. Paty, Vi Kien Chiu · 2016 · Oncotarget
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- The Power Behind the Throne: Senescence and the Hallmarks of CancerMatthew Hoare, Masashi Narita · 2017 · Annual Review of Cancer Biology
- Accumulation of senescent cells in the stroma of aged mouse ovaryNatsumi Maruyama, Isuzu FUKUNAGA, Tomoaki KOGO, Tsutomu Endo, Wataru Fujii, Masami Kanai‐Azuma, Kunihiko Naito, Koji Sugiura · 2023 · Journal of Reproduction and Development
- Molecular biology of gynecological cancerKenzo Sonoda · 2015 · Oncology Letters
- Triptolide inhibits tumor growth by induction of cellular senescenceRuidong Li, Xiaofei Zhang, Xiaoying Tian, Conghuan Shen, Quanbao Zhang, Yihong Zhang, Zhengxin Wang, Feifei Wang, Yifeng Tao · 2016 · Oncology Reports
- Targeting chemoresistant senescent pancreatic cancer cells improves conventional treatment efficacySara Jaber, Marine Warnier, Christopher Leers, Mathieu Vernier, Delphine Goehrig, Jean‐Jacques Médard, David Vindrieux, Dorian V. Ziegler, David Bernard · 2023 · Molecular Biomedicine
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- Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancerLiyuan Zhang, Zhenlong Yu, Xiaobo Wang, Xiaobo Wang, Lianru Zhang, Chao Wang, Qingxi Yue, Xun Wang, Sa Deng, Xiaokui Huo et al. · 2016 · Oncotarget
- The Intricate Interplay between Mechanisms Underlying Aging and CancerAmanda Piano · 2014 · Aging and Disease
- NQO1 Stabilizes p53 in Response to Oncogene-Induced SenescenceKaiyu Liu, Bo Jin, Chenglin Wu, Jianming Yang, Xiangwen Zhan, Le Wang, Xiaomeng Shen, Jing Chen, Hao Chen, Zebin Mao · 2015 · International Journal of Biological Sciences
- The cellular senescence of leukemia-initiating cells from acute lymphoblastic leukemia is postponed by β-Arrestin1 binding with P300-Sp1 to regulate hTERT transcriptionShan Liu, Haiyan Liu, Ru Qin, Yi Shu, Zhi-Dai Liu, Penghui Zhang, Cai‐Wen Duan, Dengli Hong, Jie Zhong Yu, Lin Zou · 2017 · Cell Death and Disease
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- The Evolution and Future of Targeted Cancer Therapy: From Nanoparticles, Oncolytic Viruses, and Oncolytic Bacteria to the Treatment of Solid TumorsKyle M. Pierce, William R. Miklavcic, Kyle P. Cook, Mikayla S. Hennen, Kenneth W. Bayles, Michael Anthony Hollingsworth, Amanda E. Brooks, Jessica E. Pullan, Kaitlin M. Dailey · 2021 · Nanomaterials
- Non-canonical functions of SNAIL drive context-specific cancer progressionM. Paul, C. Schneeweis, C. Falcomatà, Chuan Shan, Daniel Rossmeisl, Stella Koutsouli, Christine Klement, M. Żukowska, Sebastian A. Widholz, M. Jesinghaus et al. · 2023 · Nature Communications
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- Overexpression of Tyro3 receptor tyrosine kinase leads to the acquisition of taxol resistance in ovarian cancer cellsChuHee Lee · 2012 · Molecular Medicine Reports
- RSK4 inhibition results in bypass of stress-induced and oncogene-induced senescenceLaura López-Vicente, B. Pons, Laura Coch, Cristina Teixidó, Javier Hernández‐Losa, Gemma Armengol, Santiago Ramón y Cajal · 2011 · Carcinogenesis
- Antagonistic TSC22D1 variants control BRAFE600‐induced senescenceHömig-Hölzel Cornelia, Remco van Doorn, Celia Vogel, Markus Germann, Marco G. Cecchini, Els M.E. Verdegaal, Daniel S. Peeper · 2011 · The EMBO Journal
- Depletion of FOXM1 via MET Targeting Underlies Establishment of a DNA Damage–Induced Senescence Program in Gastric CancerPaola Francica, Lluís Nisa, Daniel M. Aebersold, Rupert Langer, Friedhelm Bladt, Andree Blaukat, Deborah Stroka, María Rodríguez Martínez, Yitzhak Zimmer, Michaela Medová · 2016 · Clinical Cancer Research
- The DNA repair function ofCUX1contributes to radioresistanceZubaidah M. Ramdzan, Vasudeva Ginjala, Jordan B. Pinder, Dudley Chung, Caroline M. Donovan, Simran Jeet Kaur, Lam Leduy, Graham Dellaire, Shridar Ganesan, Alain Nepveu · 2017 · Oncotarget
- The Role of Kinase Modulators in Cellular Senescence for Use in Cancer TreatmentChang Won Lee, Juhwa Baek, Sun‐Young Han · 2017 · Molecules
- Coroglaucigenin induces senescence and autophagy in colorectal cancer cellsYonghao Huang, Jing Lei, Guohui Yi, Feng‐Ying Huang, Yue‐Nan Li, Cai‐Chun Wang, Yan Sun, Hao‐Fu Dai, Guang‐Hong Tan · 2018 · Cell Proliferation
- Radiation-Induced Senescence Reprograms Secretory and Metabolic Pathways in Colon Cancer HCT-116 CellsChandrasekharam N. Nagineni, Sarwat Naz, Rajani Choudhuri, Gadisetti V.R. Chandramouli, Murali Cherukuri Krishna, Jeffrey Brender, John A. Cook, James B. Mitchell · 2021 · International Journal of Molecular Sciences
- Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesisYukinari Haraoka, Yuki Akieda, Yuri Nagai, Chihiro Mogi, Tohru Ishitani · 2022 · Nature Communications
- Evaluation of premature senescence and senescence biomarkers in carcinoma cells and xenograft mice exposed to single or fractionated irradiationBong Cho Kim, HEE JUNG YOO, Hyung‐Chul Lee, Kyoung Ah Kang, Seung Hee Jung, Hae June Lee, Minyoung Lee, Seung Woo Park, YOUNG-HOON JI, Yun-Sil Lee et al. · 2014 · Oncology Reports
- Ral GTPase Down-regulation Stabilizes and Reactivates p53 to Inhibit Malignant TransformationAwet Tecleab, Xiaolei Zhang, Saı̈d M. Sebti · 2014 · Journal of Biological Chemistry
- The CEACAM1 tumor suppressor is an ATM and p53-regulated gene required for the induction of cellular senescence by DNA damageA-P Sappino, Raphaële Buser, Q Seguin, Marie Fernet, Laurence Lesne, Fabienne Gumy‐Pause, Walter Reith, Vincent Favaudon, Stefano J. Mandriota · 2012 · Oncogenesis
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- Depletion of γ-glutamylcyclotransferase inhibits breast cancer cell growth via cellular senescence induction mediated by CDK inhibitor upregulationKengo Matsumura, Susumu Nakata, Keiko Taniguchi, Hiromi Ii, Eishi Ashihara, Susumu Kageyama, Akihiro Kawauchi, Tatsuhiro Yoshiki · 2016 · BMC Cancer
- Correction: Nuclear receptor HNF4α performs a tumor suppressor function in prostate cancer via its induction of p21-driven cellular senescenceZhu Wang, Youjia Li, Dinglan Wu, Shan Yu, Yuliang Wang, Franky Leung Chan · 2020 · Oncogene
- Inhibiting Enhancer of Zeste Homolog 2 Promotes Cellular Senescence in Gastric Cancer Cells SGC-7901 by Activation of p21 and p16Jie Bai, Junhua Chen, Muyuan Ma, Ming Cai, Fei Xu, Guobin Wang, Kaixiong Tao, Xiaoming Shuai · 2014 · DNA and Cell Biology
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- SIX1 represses senescence and promotes SOX2-mediated cellular plasticity during tumorigenesisCristina De Lope, Samara Martín-Alonso, Jaione Auzmendi-Iriarte, Carmen Escudero‐Iriarte, Isabel Mulet, Javier Larrasa-Alonso, Irene López‐Antona, Ander Matheu, Ignacio Palmero · 2019 · Scientific Reports
- Molecular Mechanisms to Target Cellular Senescence in Hepatocellular CarcinomaConstanze Mittermeier, Andreas Konopa, Susanne Muehlich · 2020 · Cells
- ERK phosphorylation and nuclear accumulation: insights from single-cell imagingChristopher James Caunt, Craig Alexander McArdle · 2012 · Biochemical Society Transactions
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