The DREAM complex: master coordinator of cell cycle-dependent gene expression

Molecular portraits of human breast tumours

Perou, C., Sørlie, T., Eisen, M., van de Rijn, M., Jeffrey, S., Rees, C. A., Pollack, J., Ross, D., Johnsen, H., Akslen, L., et al. (2000) · Nature · doi:10.1038/35021093 · Cited by 16,551

Integrated genomic analyses of ovarian carcinoma

Perou, C. M. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/hvp3-wg08 · Cited by 7,927

A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer

Paik, S., Shak, S., Tang, G., Kim, C., Baker, J. B., Cronin, M. T., Baehner, F. L., Walker, M. G., Watson, D., Park, T., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa041588 · Cited by 6,321

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Serrano, M., Lin, A. W., McCurrach, M. E., Beach, D., & Lowe, S. W. (1997) · Cell · doi:10.1016/s0092-8674(00)81902-9 · Cited by 5,218

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Zhao, B., Wei, X., Li, W., Udan, R. S., Yang, Q., Kim, J., Xie, J., Ikenoue, T., Yu, J., Li, L., et al. (2007) · Genes & Development · doi:10.1101/gad.1602907 · Cited by 3,092

The Hippo Signaling Pathway Coordinately Regulates Cell Proliferation and Apoptosis by Inactivating Yorkie, the Drosophila Homolog of YAP

Huang, J., Wu, S., Barrera, J. A., Matthews, K. A., & Pan, D. (2005) · Cell · doi:10.1016/j.cell.2005.06.007 · Cited by 1,917

The Hippo pathway and human cancer

Harvey, K. F., Zhang, X., & Thomas, D. M. (2013) · Nature reviews. Cancer · doi:10.1038/nrc3458 · Cited by 1,867

Identification of Genes Periodically Expressed in the Human Cell Cycle and Their Expression in Tumors

Whitfield, M. L., Sherlock, G., Saldanha, A. J., Murray, J. I., Ball, C. A., Alexander, K. E., Matese, J. C., Perou, C. M., Hurt, M. M., Brown, P. O., et al. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.02-02-0030 · Cited by 1,527

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF β-TRCP

Zhao, B., Li, L., Tumaneng, K., Wang, C.-Y., & Guan, K.-L. (2010) · Genes & Development · doi:10.1101/gad.1843810 · Cited by 1,418

Linkage of E2F1 transcriptional network and cell proliferation with respiratory chain activity in breast cancer cells

Mori, K., Uchida, T., Fukumura, M., Tamiya, S., Higurashi, M., Sakai, H., Ishikawa, F., & Shibanuma, M. (2016) · Cancer Science · doi:10.1111/cas.12953 · Cited by 26

The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes

Asthana, A., Ramanan, P., Hirschi, A., Guiley, K. Z., Wijeratne, T. U., Shelansky, R. I., Doody, M. J., Narasimhan, H., Boeger, H., Tripathi, S. M., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28094-1 · Cited by 25

Genetic origins, regulators, and biomarkers of cellular senescence

Torres, G., Salladay-Perez, I. A., Dhingra, A., & Covarrubias, A. J. (2024) · Trends in Genetics · doi:10.1016/j.tig.2024.08.007 · Cited by 24

Msa1 and Msa2 Modulate G1-Specific Transcription to Promote G1 Arrest and the Transition to Quiescence in Budding Yeast

Miles, S., Croxford, M. A., Abeysinghe, A. P., & Breeden, L. L. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1006088 · Cited by 24

Predicting FOXM1-Mediated Gene Regulation through the Analysis of Genome-Wide FOXM1 Binding Sites in MCF-7, K562, SK-N-SH, GM12878 and ECC-1 Cell Lines

Kang, K., Choi, Y., Kim, H. H., Yoo, K. H., & Yu, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21176141 · Cited by 24

Emerging Mechanisms of G 1 /S Cell Cycle Control by Human and Mouse Cytomegaloviruses

Bogdanow, B., Phan, Q. V., & Wiebusch, L. (2021) · mBio · doi:10.1128/mbio.02934-21 · Cited by 24

Role of Cdk1 in DNA damage-induced G1 checkpoint abrogation by the human papillomavirus E7 oncogene

Fan, X., & Chen, J. J. (2014) · Cell Cycle · doi:10.4161/15384101.2014.953879 · Cited by 24

Generation of highly potent DYRK1A-dependent inducers of human β-Cell replication via Multi-Dimensional compound optimization

Allegretti, P. A., Horton, T. M., Abdolazimi, Y., Moeller, H. P., Yeh, B. T., Caffet, M., Michel, G., Smith, M. A., & Annes, J. P. (2019) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2019.115193 · Cited by 24

MYBL2 and ATM suppress replication stress in pluripotent stem cells

Blakemore, D., Vilaplana‐Lopera, N., Almaghrabi, R. O. M., Gonzalez, E., Moya, M., Ward, C., Murphy, G. J., Gambus, A., Petermann, E., Stewart, G. S., et al. (2021) · EMBO Reports · doi:10.15252/embr.202051120 · Cited by 25

Multiomic single cell sequencing identifies stemlike nature of mixed phenotype acute leukemia

Peretz, C. A. C., Kennedy, V. E., Walia, A., Delley, C. L., Koh, A., Tran, E., Clark, I. C., Hayford, C. E., D’Amato, C., Xue, Y., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-52317-2 · Cited by 23

PCLAF-DREAM drives alveolar cell plasticity for lung regeneration

Kim, B.-J., Huang, Y., Ko, K.-P., Zhang, S., Zou, G., Zhang, J., Kim, M. J., Little, D. T., Ellis, L. V., Paschini, M., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-53330-1 · Cited by 25

Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila

Nabeel‐Shah, S., Garg, J., Saettone, A., Ashraf, K., Lee, H., Wahab, S., Ahmed, N., Fine, J. L., Derynck, J., Pu, S., et al. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab413 · Cited by 23

Insights from the protein interaction Universe of the multifunctional “Goldilocks” kinase DYRK1A

Ananthapadmanabhan, V., Shows, K. H., DICKINSON, A. J. G., & Litovchick, L. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1277537 · Cited by 23

Stable Phenotypic Changes of the Host T Cells Are Essential to the Long-Term Stability of Latent HIV-1 Infection

Seu, L., Sabbaj, S., Duverger, A. E., Wagner, F., Anderson, J. C., Davies, E., Wolschendorf, F., Willey, C. D., Saag, M. S., Goepfert, P., et al. (2015) · Journal of Virology · doi:10.1128/jvi.00571-15 · Cited by 23

Role of WDHD1 in Human Papillomavirus-Mediated Oncogenesis Identified by Transcriptional Profiling of E7-Expressing Cells

Zhou, Y., Zhang, Q., Gao, G., Zhang, X., Liu, Y., Yuan, S., Wang, X., & Chen, J. J. (2016) · Journal of Virology · doi:10.1128/jvi.00513-16 · Cited by 23

ELF4 Is a Target of miR-124 and Promotes Neuroblastoma Proliferation and Undifferentiated State

Kosti, A., Du, L., Shivram, H., Qiao, M., Burns, S. S., Garcia, J. G., Pertsemlidis, A., Iyer, V. R., Kokovay, E., & Penalva, L. O. F. (2019) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-19-0187 · Cited by 23

Advances in therapeutic agents targeting quiescent cancer cells

Nabil, W. N. N., Xi, Z., Liu, M., Li, Y., Mu, Y., Liu, T., Dong, Q., & Xu, H. (2022) · Acta Materia Medica · doi:10.15212/amm-2021-0005 · Cited by 22

L(3)mbt and the LINT complex safeguard cellular identity in the Drosophila ovary

Coux, R.-X., Teixeira, F. K., & Lehmann, R. (2018) · Development · doi:10.1242/dev.160721 · Cited by 22

Targeting Cancer Metabolism and Cell Cycle by Plant-Derived Compounds

Aydemir, E., Tecimel, D., Şahi̇n, F., & Deniz, A. A. H. (2019) · Advances in experimental medicine and biology · doi:10.1007/5584_2019_449 · Cited by 22

Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer’s disease

Valdes, P., Caldwell, A. B., Liu, Q., Fitzgerald, M. Q., Ramachandran, S., Karch, C. M. M., Dominantly Inherited Alzheimer Network (DIAN), Adams, S., Allegri, R., Araki, A., et al. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01659-6 · Cited by 25

Does Arabidopsis thaliana DREAM of cell cycle control?

Fischer, M., & DeCaprio, J. A. (2015) · The EMBO Journal · doi:10.15252/embj.201592196 · Cited by 21

The association of mammalian DREAM complex and HPV16 E7 proteins.

Rashid, N. N., Rothan, H. A., & Yusoff, M. S. M. (2015) · PubMed Central · Cited by 21

New insights into tumor dormancy: Targeting DNA repair pathways

Evans, E. B. (2015) · World Journal of Clinical Oncology · doi:10.5306/wjco.v6.i5.80 · Cited by 21

Sizing up the cell cycle: systems and quantitative approaches in Chlamydomonas

Umen, J. (2018) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2018.08.003 · Cited by 21

Prognostic implications and oncogenic roles of MYBL2 protein expression in esophageal squamous-cell carcinoma

Qin, H., Li, Y., Zhang, H., Wang, F., He, H., Bai, X., & Li, S. (2019) · OncoTargets and Therapy · doi:10.2147/ott.s190145 · Cited by 21

Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2

Enrico, T. P., Stallaert, W., Wick, E. T., Ngoi, P., Wang, X., Rubin, S. M., Brown, N. G., Purvis, J. E., & Emanuele, M. J. (2021) · eLife · doi:10.7554/elife.70691 · Cited by 24

Roles for the Histone Modifying and Exchange Complex NuA4 in Cell Cycle Progression in Drosophila melanogaster

Flegel, K. A., Grushko, O., Bolin, K., Griggs, E., & Buttitta, L. (2016) · Genetics · doi:10.1534/genetics.116.188581 · Cited by 25

Protoparvovirus Interactions with the Cellular DNA Damage Response

Majumder, K., Etingov, I., & Pintel, D. J. (2017) · Viruses · doi:10.3390/v9110323 · Cited by 21

PBAF loss leads to DNA damage-induced inflammatory signaling through defective G2/M checkpoint maintenancePreprint

Feng, H., Lane, K. A., Roumeliotis, T. I., Jeggo, P. A., Somaiah, N., Choudhary, J. S., & Downs, J. A. (2022) · Genes & Development · doi:10.1101/gad.349249.121 · Cited by 23

FAM72, Glioblastoma Multiforme (GBM) and Beyond

Ho, N. T. T., Rahane, C. S., Pramanik, S., Kim, P., Kutzner, A., & Heese, K. (2021) · Cancers · doi:10.3390/cancers13051025 · Cited by 20

Examining the mechanistic relationship of APC / CCDH1 and its interphase inhibitor EMI1

Bolhuis, D. L., Martinez‐Chacin, R. C., Welsh, K. A., Bodrug, T., Cui, L., Emanuele, M. J., & Brown, N. G. (2022) · Protein Science · doi:10.1002/pro.4324 · Cited by 20

Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting

Gimple, R. C., Zhang, G., Wang, S., Huang, T., Lee, J., Taori, S., Lv, D., Dixit, D., Halbert, M. E., Morton, A. R., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.158077 · Cited by 20

Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence

Savić, R., Yang, J., Koplev, S., An, M. C., Patel, P. L., O’Brien, R., Dubose, B. N., Dodatko, T., Rogatsky, E., Sukhavasi, K., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.113371 · Cited by 21

Exploring the Histone Acetylation Cycle in the Protozoan Model Tetrahymena thermophila

Wahab, S., Saettone, A., Nabeel‐Shah, S., Dannah, N. S., & Fillingham, J. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00509 · Cited by 21

Interplay between HMGA and TP53 in cell cycle control along tumor progression

Costa, N. M. D., Palumbo, A., Martino, M. D., Fusco, A., Pinto, L. F. R., & Nasciutti, L. E. (2020) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-020-03634-4 · Cited by 20

Early-Stage Lung Adenocarcinoma MDM2 Genomic Amplification Predicts Clinical Outcome and Response to Targeted Therapy

Sinha, A., Zou, Y., Patel, A. S., Yoo, S., Jiang, F., Sato, T., Kong, R., Watanabe, H., Zhu, J., Massion, P. P., et al. (2022) · Cancers · doi:10.3390/cancers14030708 · Cited by 20

Lung Cancer Gene Regulatory Network of Transcription Factors Related to the Hallmarks of Cancer

Otálora-Otálora, B. A., López-Kleine, L., & Rojas, A. P. (2023) · Current Issues in Molecular Biology · doi:10.3390/cimb45010029 · Cited by 20

DREAM represses distinct targets by cooperating with different THAP domain proteins

Gal, C., Carelli, F. N., Appert, A., Cerrato, C., Huang, N., Yan, D., Murphy, J., Frapporti, A., & Ahringer, J. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109835 · Cited by 19

Downstream Regulatory Network of MYBL2 Mediating Its Oncogenic Role in Melanoma

Zhong, F., Liu, J., Gao, C., Chen, T., & Li, B. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.816070 · Cited by 19

Arabidopsis MAS2, an Essential Gene That Encodes a Homolog of Animal NF-κ B Activating Protein, Is Involved in 45S Ribosomal DNA Silencing

Sánchez‐García, A. B., Aguilera, V., Micol‐Ponce, R., Jover‐Gil, S., & Ponce, M. R. (2015) · The Plant Cell · doi:10.1105/tpc.15.00135 · Cited by 19

Cell Cycle Commitment and the Origins of Cell Cycle Variability

Brooks, R. F. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.698066 · Cited by 20

Increased MYBL2 expression in aggressive hormone‐sensitive prostate cancer

Yoshikawa, Y., Stopsack, K. H., Wang, V., Chen, Y., Mazzu, Y. Z., Burton, F., Chakraborty, G., Rajanala, S. H., Hirani, R., Nandakumar, S., et al. (2022) · Molecular Oncology · doi:10.1002/1878-0261.13314 · Cited by 18

The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex–mediated quiescence

Greenberg, Z. J., Paracatu, L. C., Monlish, D. A., Dong, Q., Rettig, M. P., Roundy, N., Gaballa, R., Li, W., Yang, W., Luke, C. J., et al. (2022) · Blood · doi:10.1182/blood.2022016929 · Cited by 18

Broad repression of DNA repair genes in senescent cells identified by integration of transcriptomic data

Frey, Y., Haj, M., Ziv, Y., Elkon, R., & Shiloh, Y. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae1257 · Cited by 18

MAZ induces MYB expression during the exit from quiescence via the E2F site in the MYB promoter

Álvaro-Blanco, J., Urso, K., Chiodo, Y., Martín-Cortázar, C., Kourani, O., Arco, P. G., Rodríguez‐Martínez, M., Calonge, E., Alcamı́, J., Redondo, J. M., et al. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx641 · Cited by 18

Transcriptomic Characterization of the Human Cell Cycle in Individual Unsynchronized Cells

Karlsson, J. W., Kroneis, T., Jonasson, E., Larsson, E., & Ståhlberg, A. (2017) · Journal of Molecular Biology · doi:10.1016/j.jmb.2017.10.011 · Cited by 18

Cellular feedback dynamics and multilevel regulation driven by the hippo pathway

Park, J., & Hansen, C. G. (2021) · Biochemical Society Transactions · doi:10.1042/bst20200253 · Cited by 19

Gene expression analysis during progression of malignant meningioma compared to benign meningioma

Maier, A. D., Meddis, A., Mirian, C., Haslund-Vinding, J. L., Bartek, J. J., Krog, S. M., Nguyen, T. U. P., Areškevičiūtė, A., Melchior, L. C., Heegaard, S., et al. (2022) · Journal of neurosurgery · doi:10.3171/2022.7.jns22585 · Cited by 18

Contribution of LATS1 and LATS2 promoter methylation in OSCC development

Rigi‐Ladiz, M. A., Najafi, M., & Kordi-Tamandani, D. M. (2016) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-016-0356-4 · Cited by 18

An atrial fibrillation-associated regulatory region modulates cardiac Tbx5 levels and arrhythmia susceptibility

Bosada, F. M., van Duijvenboden, K., Giovou, A. E., Rivaud, M. R., Uhm, J., Verkerk, A. O., Boukens, B. J., & Christoffels, V. M. (2023) · eLife · doi:10.7554/elife.80317 · Cited by 17

Tumour suppressors and cellular senescence

Chan, A. S. L., Mowla, S. N., Arora, P., & Jat, P. (2014) · IUBMB Life · doi:10.1002/iub.1335 · Cited by 20

E2F4 Promotes Neuronal Regeneration and Functional Recovery after Spinal Cord Injury in Zebrafish

Sasagawa, S., Nishimura, Y., Hayakawa, Y., Murakami, S., Ashikawa, Y., Yuge, M., Okabe, S., Kawaguchi, K., Kawase, R., & Tanaka, T. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00119 · Cited by 17

Gene network analysis using SWIM reveals interplay between the transcription factor‐encoding genes HMGA1, FOXM1, and MYBL2 in triple‐negative breast cancer

Fiscon, G., Pegoraro, S., Conte, F., Manfioletti, G., & Paci, P. (2021) · FEBS Letters · doi:10.1002/1873-3468.14085 · Cited by 17

E2Fb and E2Fa transcription factors independently regulate the DNA damage response after ultraviolet B exposure in Arabidopsis

Gómez, M. S., Sheridan, M. L., & Casati, P. (2021) · The Plant Journal · doi:10.1111/tpj.15616 · Cited by 17

Structure and function of MuvB complexes

Müller, G. A., Asthana, A., & Rubin, S. M. (2022) · Oncogene · doi:10.1038/s41388-022-02321-x · Cited by 17

Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma

Tran, G., Ding, J., Ye, B., Liu, M., Yu, Y., Zha, Y., Dong, Z., Liu, K., Sudarshan, S., & Ding, H. (2023) · Cancer Research · doi:10.1158/0008-5472.can-22-3450 · Cited by 16

Regulation of early seedling establishment and root development in Arabidopsis thaliana by light and carbohydrates

Pasternak, T. P., Kircher, S., Palme, K. J., & Pérez‐Pérez, J. M. (2023) · Planta · doi:10.1007/s00425-023-04226-9 · Cited by 16

Multiciliogenesis: Multicilin Directs Transcriptional Activation of Centriole Formation

Balestra, F. R., & Gönczy, P. (2014) · Current Biology · doi:10.1016/j.cub.2014.07.006 · Cited by 16

Natural (and Unnatural) Small Molecules as Pharmacological Chaperones and Inhibitors in Cancer

Betancor-Fernández, I., Timson, D. J., SALIDO, E. C., & Pey, A. L. (2017) · Handbook of experimental pharmacology · doi:10.1007/164_2017_55 · Cited by 16

Abundance of d ‐2‐hydroxyglutarate in G2/M is determined by FOXM1 in mutant IDH1‐expressing cells

Kancharana, B., Katragunta, K., Sarma, U. M., & Jain, N. (2019) · FEBS Letters · doi:10.1002/1873-3468.13500 · Cited by 16

Minibrain-related kinase/dual-specificity tyrosine-regulated kinase 1B implication in stem/cancer stem cells biology

Kokkorakis, N., & Gaitanou, M. (2020) · World Journal of Stem Cells · doi:10.4252/wjsc.v12.i12.1553 · Cited by 16

Mitogen Synergy: An Emerging Route to Boosting Human Beta Cell Proliferation

Shcheglova, E. G., Błaszczyk, K., & Borowiak, M. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.734597 · Cited by 18

Rbbp4 loss disrupts neural progenitor cell cycle regulation independent of Rb and leads to Tp53 acetylation and apoptosis

Schultz‐Rogers, L. E., Thayer, M. L., Kambakam, S., Wierson, W. A., Helmer, J. A., Wishman, M. D., Wall, K. A., Greig, J. L., Forsman, J. L., Puchhalapalli, K., et al. (2022) · Developmental Dynamics · doi:10.1002/dvdy.467 · Cited by 16

Piperine–Chlorogenic Acid Hybrid Inhibits the Proliferation of the SK-MEL-147 Melanoma Cells by Modulating Mitotic Kinases

Pressete, C. G., Viegas, F. P. D., Campos, T. G., Caixeta, E. S., Hanemann, J. A. C., Ferreira‐Silva, G. Á., Zavan, B., Aissa, A. F., Miyazawa, M., Viegas, C., et al. (2023) · Pharmaceuticals · doi:10.3390/ph16020145 · Cited by 16

Hcm1 integrates signals from Cdk1 and calcineurin to control cell proliferation

Arsenault, H. E., Roy, J., Mapa, C., Cyert, M., & Benanti, J. A. (2015) · Molecular Biology of the Cell · doi:10.1091/mbc.e15-07-0469 · Cited by 16

Alterations of presynaptic proteins in autism spectrum disorder

Yeo, X. Y., Lim, Y. T., Chae, W. R., Park, C., Park, H., & Jung, S. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.1062878 · Cited by 16

miR-200b/MYBL2/CDK1 suppresses proliferation and induces senescence through cell cycle arrest in ovine granulosa cells

Song, P., Chen, X., Zhang, P., Zhou, Y., & Zhou, R. (2023) · Theriogenology · doi:10.1016/j.theriogenology.2023.05.022 · Cited by 15

The microtubule-associated protein PRC1 is a potential therapeutic target for lung cancer

Hanselmann, S., Wolter, P., Malkmus, J., & Gaubatz, S. (2017) · Oncotarget · doi:10.18632/oncotarget.23577 · Cited by 16

Translating RB1 predictive value in clinical cancer therapy: Are we there yet?

Indovina, P., Pentimalli, F., Conti, D., & Giordano, A. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.06.003 · Cited by 15

The coordinate actions of calcineurin and Hog1 mediate the stress response through multiple nodes of the cell cycle network

Leech, C. M., Flynn, M. J., Arsenault, H. E., Ou, J., Liu, H., Zhu, L. J., & Benanti, J. A. (2020) · PLoS Genetics · doi:10.1371/journal.pgen.1008600 · Cited by 17

Restoring the DREAM Complex Inhibits the Proliferation of High-Risk HPV Positive Human Cells

James, C. D., Saini, S., Sesay, F. F., Ko, K., Felthousen, J. G., Iness, A. N., Nulton, T. J., Windle, B. E., Dozmorov, M. G., Morgan, I. M., et al. (2021) · Cancers · doi:10.3390/cancers13030489 · Cited by 16

Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer's disease

Caldwell, A. B., Liu, Q., Zhang, C. M., Schroth, G. P., Galasko, D. R., Rynearson, K. D., Tanzi, R. E., Yuan, S. H., Wagner, S. L., & Subramaniam, S. (2022) · Alzheimer s & Dementia · doi:10.1002/alz.12553 · Cited by 16

Structure of a nucleosome-bound MuvB transcription factor complex reveals DNA remodelling

Koliopoulos, M. G., Muhammad, R., Roumeliotis, T. I., Beuron, F., Choudhary, J. S., & Alfieri, C. (2022) · Nature Communications · doi:10.1038/s41467-022-32798-9 · Cited by 16

SmgGDS is a transient nucleolar protein that protects cells from nucleolar stress and promotes the cell cycle by regulating DREAM complex gene expression

Gonyo, P., Bergom, C. R., Brandt, A. C., Tsaih, S.-W., Sun, Y., Bigley, T. M., Lorimer, E., Terhune, S. S., Rui, H., Flister, M. J., et al. (2017) · Oncogene · doi:10.1038/onc.2017.280 · Cited by 15

An RNAi Screen for Genes Required for Growth ofDrosophilaWing Tissue

Rotelli, M. D., Bolling, A. M., Killion, A. W., Weinberg, A. J., Dixon, M. J., & Calvi, B. R. (2019) · G3 Genes Genomes Genetics · doi:10.1534/g3.119.400581 · Cited by 15

Clinical Implications of Chromosomal Instability (CIN) and Kinetochore Abnormalities in Breast Cancers

Voutsadakis, I. A. (2019) · Molecular Diagnosis & Therapy · doi:10.1007/s40291-019-00420-2 · Cited by 15

B-MYB—p53-related relevant regulator for the progression of clear cell renal cell carcinoma

Nientiedt, M., Müller, K., Nitschke, K., Erben, P., Steidler, A., Porubský, Š., Popović, Z. V., Waldbillig, F., Mühlbauer, J., & KRIEGMAIR, M. C. (2020) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-020-03392-7 · Cited by 14

DREAM a little dREAM of DRM: Model organisms and conservation of DREAM‐like complexes

Hoareau, M., Rincheval‐Arnold, A., Gaumer, S., & Guénal, I. (2023) · BioEssays · doi:10.1002/bies.202300125 · Cited by 14

In vivo CRISPR/Cas9-mediated screen reveals a critical function of TFDP1 and E2F4 transcription factors in hematopoiesis

Tran, N. T., Graf, R., Acevedo‐Ochoa, E., Trombke, J., Weber, T., Sommermann, T. G., Salomon, C., Kühn, R., Rajewsky, K., & Chu, V. T. (2024) · Leukemia · doi:10.1038/s41375-024-02357-w · Cited by 16

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Boekenkamp, J.-E., Keuper, K., Redel, S., Barthel, K., Johnson, L., Becker, A., Wieland, A., Räschle, M., & Štorchová, Z. (2025) · The EMBO Journal · doi:10.1038/s44318-025-00372-w · Cited by 14

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Higurashi, M., Maruyama, T., Nogami, Y., Ishikawa, F., Yoshida, Y., Mori, K., Fujita, K., & Shibanuma, M. (2020) · Experimental Cell Research · doi:10.1016/j.yexcr.2020.111889 · Cited by 14

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Gazzillo, A., Volponi, C., Soldani, C., Polidoro, M. A., Franceschini, B., Lleò, A., Bonavita, E., & Donadon, M. (2023) · Biomedicines · doi:10.3390/biomedicines12010026 · Cited by 14

Drosophila dany is essential for transcriptional control and nuclear architecture in spermatocytes

Trost, M., Blattner, A. C., Léo, S., & Lehner, C. F. (2016) · Development · doi:10.1242/dev.134759 · Cited by 14

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Fuller, M. S., Majumder, K., & Pintel, D. J. (2017) · Journal of Virology · doi:10.1128/jvi.00428-17 · Cited by 14

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Chen, Q., Liu, J., Wu, J., Xiang, X., Zhou, X., Mi, J., Wei, J., Zou, X., & Wu, A. (2026) · Drug Resistance Updates · doi:10.1016/j.drup.2026.101363 · Cited by 15

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Zhang, L., Cervantes, M. D., Pan, S., Lindsley, J., Dabney, A. R., & Kapler, G. M. (2022) · Molecular Biology of the Cell · doi:10.1091/mbc.e22-08-0326 · Cited by 13

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Kumari, R., Hummerich, H., Shen, X., Fischer, M., Litovchick, L., Mittnacht, S., DeCaprio, J. A., & Jat, P. (2021) · Scientific Reports · doi:10.1038/s41598-021-01012-z · Cited by 13

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Roelofs, P. A., Timmermans, M. A. M., Stefanovska, B., den Boestert, M. A., van den Borne, A. W. M., Balcioglu, H. E., Trapman-Jansen, A., Harris, R. S., Martens, J. W. M., & Span, P. N. (2023) · Cells · doi:10.3390/cells12081185 · Cited by 14

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Li, X., Zhang, X., Wu, C., Li, P., Fu, Y., Xie, L., Sun, S., Zhou, Y., & Zhu, B. (2020) · Journal of Molecular Histology · doi:10.1007/s10735-020-09920-6 · Cited by 13

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