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Cited by 344

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

DNA helicases involved in DNA repair and their roles in cancer

Open access
Brosh, Robert M.·2013·Nature Reviews Cancer

Abstract

Helicases have major roles in genome maintenance by unwinding structured nucleic acids. Their prominence is marked by various cancers and genetic disorders that are linked to helicase defects. Although considerable effort has been made to understand the functions of DNA helicases that are important for genomic stability and cellular homeostasis, the complexity of the DNA damage response leaves us with unanswered questions regarding how helicase-dependent DNA repair pathways are regulated and coordinated with cell cycle checkpoints. Further studies may open the door to targeting helicases in order to improve cancer treatments based on DNA-damaging chemotherapy or radiation.

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Metadata

Authors
Brosh, R. M.
Venue
Nature Reviews Cancer
Published
2013-07-11
Volume
13
Issue
8
Pages
542-558
ISSN
  • 1474-175X (ISSN-L)
  • 1474-1768
OpenAlex
W1970843450
Cited by
344
References
23
FWCI
2.49
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: DNA helicases involved in DNA repair and their roles in cancer. https://app.cochat.ai/papers/10.1038/nrc3560
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Brosh, R. M. (2013). DNA helicases involved in DNA repair and their roles in cancer. Nature Reviews Cancer. https://doi.org/10.1038/nrc3560

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.