Therapeutic opportunities within the DNA damage response

Pearl, Laurence H., Schierz, Amanda C., Ward, Simon E., Al-Lazikani, Bissan, Pearl, Frances M. G.·2015·Nature Reviews Cancer
DOI 10.1038/nrc3891

Cited by (578)

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  15. Knockdown of the nucleoporin Nup50 protects cells against ionizing radiation through enhancing DNA-PKcs-mediated DNA damage repair
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  17. Reviewer #1 (Public Review): Repression of PRMT activities sensitize homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment
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  27. Additional file 4 of DNA damage response alterations in clear cell renal cell carcinoma: clinical, molecular, and prognostic implications
    Jing, Xiao, Xiangcheng Qin, Liu, Hao, Liu, Huanhuan, Wang, Huina, Qin, Jiayue, Yanui Zhang, Cao, Shanbo, Fan, Xiaodong · 2024 · Figshare
  28. Additional file 1 of DNA damage response alterations in clear cell renal cell carcinoma: clinical, molecular, and prognostic implications
    Jing, Xiao, Xiangcheng Qin, Liu, Hao, Liu, Huanhuan, Wang, Huina, Qin, Jiayue, Yanui Zhang, Cao, Shanbo, Fan, Xiaodong · 2024 · Figshare
  29. Additional file 14 of Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
    Bianca Walter, Hirsch, Sophie, Laurence Kuhlburger, Stahl, Aaron, Leonard Schnabel, Silas Wisser, Lara Annina Haeusser, Foteini Tsiami, Sarah Plöger, Narges Aghaallaei et al. · 2024 · Figshare
  30. Additional file 5 of DNA damage response alterations in clear cell renal cell carcinoma: clinical, molecular, and prognostic implications
    Jing, Xiao, Xiangcheng Qin, Liu, Hao, Liu, Huanhuan, Wang, Huina, Qin, Jiayue, Yanui Zhang, Cao, Shanbo, Fan, Xiaodong · 2024 · Figshare
  31. Additional file 3 of Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
    Bianca Walter, Hirsch, Sophie, Laurence Kuhlburger, Stahl, Aaron, Leonard Schnabel, Silas Wisser, Lara Annina Haeusser, Foteini Tsiami, Sarah Plöger, Narges Aghaallaei et al. · 2024 · Figshare
  32. Additional file 6 of Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
    Bianca Walter, Hirsch, Sophie, Laurence Kuhlburger, Stahl, Aaron, Leonard Schnabel, Silas Wisser, Lara Annina Haeusser, Foteini Tsiami, Sarah Plöger, Narges Aghaallaei et al. · 2024 · Figshare
  33. Additional file 4 of Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
    Bianca Walter, Hirsch, Sophie, Laurence Kuhlburger, Stahl, Aaron, Leonard Schnabel, Silas Wisser, Lara Annina Haeusser, Foteini Tsiami, Sarah Plöger, Narges Aghaallaei et al. · 2024 · Figshare
  34. Additional file 2 of DNA damage response alterations in clear cell renal cell carcinoma: clinical, molecular, and prognostic implications
    Jing, Xiao, Xiangcheng Qin, Liu, Hao, Huanhuan Liu, Wang, Huina, Qin, Jiayue, Yanui Zhang, Cao, Shanbo, Fan, Xiaodong · 2024 · Figshare
  35. Additional file 3 of DNA damage response alterations in clear cell renal cell carcinoma: clinical, molecular, and prognostic implications
    Jing, Xiao, Xiangcheng Qin, Liu, Hao, Liu, Huanhuan, Wang, Huina, Qin, Jiayue, Yanui Zhang, Cao, Shanbo, Fan, Xiaodong · 2024 · Figshare
  36. Additional file 13 of Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
    Bianca Walter, Hirsch, Sophie, Laurence Kuhlburger, Stahl, Aaron, Leonard Schnabel, Silas Wisser, Lara Annina Haeusser, Foteini Tsiami, Sarah Plöger, Narges Aghaallaei et al. · 2024 · Figshare
  37. Additional file 9 of Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
    Bianca Walter, Hirsch, Sophie, Laurence Kuhlburger, Aaron Stahl, Leonard Schnabel, Silas Wisser, Lara Annina Haeusser, Foteini Tsiami, Sarah Plöger, Narges Aghaallaei et al. · 2024 · Figshare
  38. Additional file 2 of Haplotype-resolved germline and somatic alterations in renal medullary carcinomas
    Tan, Kar-Tong, Kim, Hyunji, Jian Carrot‐Zhang, Zhang, Yuxiang, Kim, Won Jun, Guillaume Kugener, Jeremiah A. Wala, Thomas P. Howard, Chi, Yueh-Yun, Rameen Beroukhim et al. · 2021 · Figshare
  39. Additional file 1 of Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
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  41. Additional file 8 of Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
    Bianca Walter, Hirsch, Sophie, Laurence Kuhlburger, Stahl, Aaron, Leonard Schnabel, Silas Wisser, Lara Annina Haeusser, Foteini Tsiami, Sarah Plöger, Narges Aghaallaei et al. · 2024 · Figshare
  42. Additional file 10 of Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
    Bianca Walter, Hirsch, Sophie, Laurence Kuhlburger, Aaron Stahl, Leonard Schnabel, Silas Wisser, Lara Annina Haeusser, Foteini Tsiami, Sarah Plöger, Narges Aghaallaei et al. · 2024 · Figshare
  43. Additional file 6 of DNA damage response alterations in clear cell renal cell carcinoma: clinical, molecular, and prognostic implications
    Jing, Xiao, Xiangcheng Qin, Liu, Hao, Huanhuan Liu, Wang, Huina, Qin, Jiayue, Yanui Zhang, Cao, Shanbo, Fan, Xiaodong · 2024 · Figshare
  44. Additional file 12 of Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
    Bianca Walter, Hirsch, Sophie, Laurence Kuhlburger, Aaron Stahl, Leonard Schnabel, Silas Wisser, Lara Annina Haeusser, Foteini Tsiami, Sarah Plöger, Narges Aghaallaei et al. · 2024 · Figshare
  45. Additional file 11 of Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
    Bianca Walter, Hirsch, Sophie, Laurence Kuhlburger, Aaron Stahl, Leonard Schnabel, Silas Wisser, Lara Annina Haeusser, Foteini Tsiami, Sarah Plöger, Narges Aghaallaei et al. · 2024 · Figshare
  46. Additional file 5 of Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
    Bianca Walter, Hirsch, Sophie, Laurence Kuhlburger, Stahl, Aaron, Leonard Schnabel, Silas Wisser, Lara Annina Haeusser, Foteini Tsiami, Sarah Plöger, Narges Aghaallaei et al. · 2024 · Figshare
  47. Additional file 2 of Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
    Bianca Walter, Hirsch, Sophie, Laurence Kuhlburger, Aaron Stahl, Leonard Schnabel, Silas Wisser, Lara Annina Haeusser, Foteini Tsiami, Sarah Plöger, Narges Aghaallaei et al. · 2024 · Figshare
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  51. Additional file 7 of Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
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  53. Mutation patterns and prognostic potentiality of homologous recombination repair genes in gliomas
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