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Reducing the risk of CVD in patients with periodontitis
Abstract
The association between periodontitis and other chronic diseases, such as cardiovascular disease (CVD) and type 2 diabetes mellitus, could be related to systemic inflammation initiated by a local inflammatory challenge. Oliveira et al. have added lack of oral hygiene, and its link with systemic inflammation, to the spectrum of risk factors for CVD.
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“Patients with severe periodontitis had higher blood neutrophil counts and pro-inflammatory mediator levels (such as IL-1, IL-6, CRP, and fibrinogen) compared to healthy controls [14–17]”
From Effect of non-surgical periodontal therapy on risk markers of cardiovascular disease: a systematic review and meta-analysis (2024) · cites this paper as [15]
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Metadata
- Authors
- Genco, R. J., & Van Dyke, T. E.
- Affiliations
- University at Buffalo, State University of New York (US)
- Corresponding author
- Genco, Robert J.
- ORCID
- Genco, Robert J.
- Venue
- Nature Reviews Cardiology
- Published
- 2010-09
- Volume
- 7
- Issue
- 9
- Pages
- 479-480
- ISSN
- 1759-5002 (ISSN-L)
- 1759-5010
- OpenAlex
- W2044895821
- Cited by
- 182
- References
- 10
- Citations by year
- 2026: 7 · 2025: 12 · 2024: 18 · 2023: 18 · 2022: 14 · 2021: 15 · 2020: 12 · 2019: 14 · 2018: 15 · 2017: 7 · 2016: 6 · 2015: 14 · 2014: 7 · 2013: 10 · 2012: 9
- FWCI
- 8.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Reviews Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Health Sciences › Dentistry › General Dentistry › Dental Research and COVID-19
- Health Sciences › Dentistry › General Dentistry › Dental Health and Care Utilization
- Keywords
- periodontitis, cardiovascular disease, systemic inflammation, type 2 diabetes, oral hygiene, cardiovascular risk factors
- MeSH terms
- C-Reactive Protein, Cardiovascular Diseases, Fibrinogen, Humans, Inflammation, Oral Hygiene, Risk Factors, Lipid Metabolism, Chronic Periodontitis
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