From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors

Ashkenazi, Avi, Fairbrother, Wayne J., Leverson, Joel D., Souers, Andrew J.·2017·Nature Reviews Drug Discovery

Cited by (918)

Items 901–918 of 918

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  6. BindingDB Entry 50009085: The chemical biology of apoptosis: Revisited after 17 years.
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  10. BindingDB Entry 50002051: Design, synthesis and pharmacological evaluation of new acyl sulfonamides as potent and selective Bcl-2 inhibitors.
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  13. BindingDB Entry 50012625: Bicyclic Helical Peptides as Dual Inhibitors Selective for Bcl2A1 and Mcl-1 Proteins.
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  14. BindingDB Entry 50013404: Design, synthesis and biological evaluation of novel HDAC inhibitors with improved pharmacokinetic profile in breast cancer.
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  15. BindingDB Entry 50015437: Discovery of a Novel BCL-X
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  16. BindingDB Entry 50010702: Pro-apoptotic carboxamide analogues of natural fislatifolic acid targeting Mcl-1 and Bcl-2.
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  17. BindingDB Entry 50017769: Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells.
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  18. BindingDB Entry 50003053: Development of high potent and selective Bcl-2 inhibitors bearing the structural elements of natural product artemisinin.
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