From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors
Ashkenazi, Avi, Fairbrother, Wayne J., Leverson, Joel D., Souers, Andrew J.·2017·Nature Reviews Drug Discovery
Cited by (918)
Items 401–500 of 918
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- Glycycoumarin Sensitizes Liver Cancer Cells to ABT-737 by Targeting De Novo Lipogenesis and TOPK-Survivin AxisEnxiang Zhang, Shutao Yin, Xiaotong Lu, Linhu Ye, Lihong Fan, Hongbo Hu · 2018 · Nutrients
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- HT-SuMD: making molecular dynamics simulations suitable for fragment-based screening. A comparative study with NMRFrancesca Ferrari, Maicol Bissaro, Simone Fabbian, Jessica de Almeida Roger, Stefano Mammi, Stefano Moro, Massimo Bellanda, Mattia Sturlese · 2020 · Journal of Enzyme Inhibition and Medicinal Chemistry
- Physalis alkekengi var. franchetii Extracts Exert Antitumor Effects on Non-Small Cell Lung Cancer and Multiple Myeloma by Inhibiting STAT3 SignalingYu‐Fei Fu, Fanfan Zhu, Zhongjun Ma, Bin Lü, Xi Wang, Chunyan Dai, Xiaoqiong Ma, Pei Liu, Hang Lv, Xin Chen et al. · 2021 · OncoTargets and Therapy
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- Hypoxia Induces Apoptosis through HIF-1α Signaling Pathway in Human Uterosacral Ligaments of Pelvic Organ ProlapseXinrui Zhao, Congcong Ma, Rui Li, Jing Xue, Lidong Liu, Peishu Liu · 2017 · BioMed Research International
- Enantiomeric trans β-aryl-δ-iodo-γ-lactones derived from 2,5-dimethylbenzaldehyde induce apoptosis in canine lymphoma cell lines by downregulation of anti-apoptotic Bcl-2 family members Bcl-xL and Bcl-2Aleksandra Pawlak, Witold Gładkowski, Justyna Kutkowska, Marcelina Mazur, Bożena Obmińska‐Mrukowicz, Andrzej Rapak · 2018 · Bioorganic & Medicinal Chemistry Letters
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- Combined BCL-2 and PI3K/AKT Pathway Inhibition in KMT2A-Rearranged Acute B-Lymphoblastic Leukemia CellsClemens Holz, Sandra Lange, Anett Sekora, Gudrun Knuebel, Saskia Krohn, Hugo Murua Escobar, Christian Junghanß, Anna Richter · 2023 · International Journal of Molecular Sciences
- Neuroinvasive virus utilizes a lipid droplet surface protein, perilipin2, to restrict apoptosis by decreasing Bcl-2 ubiquitinationQianruo Wang, Jianqing Zhao, Mai Zhang, Meixin Sun, Zhen Fang Fu, Ling Zhao, Ming Zhou · 2024 · Journal of Virology
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- Flow Cytometry-Based Detection and Analysis of BCL-2 Family Proteins and Mitochondrial Outer Membrane Permeabilization (MOMP)Lindsey M. Ludwig, Katrina L. Maxcy, James L. LaBelle · 2018 · Methods in molecular biology
- Structure‐based design, synthesis, and evaluation of Bcl‐2/Mcl‐1 dual inhibitorsJunjie Zhu, Ziqian Wang, Zongwei Guo, Xiaodong Zhang, Ting Song, Yafei Guo, Tong Ji, Zhichao Zhang · 2020 · Archiv der Pharmazie
- Wogonin reduces cardiomyocyte apoptosis from mitochondrial release of cytochrome c to improve doxorubicin‑induced cardiotoxicityYun‐Jie Wei, Junhao Zhao, Jian Xiong, Jingjing Chai, Xi Yang, Junfeng Wang, Jiajuan Chen, Jing Wang · 2022 · Experimental and Therapeutic Medicine
- BCL-2 isoform β promotes angiogenesis by TRiC-mediated upregulation of VEGF-A in lymphomaXiaohang Hang, Lei Zhao, Baohong Wu, Shujun Li, Pengpeng Liu, Jing Xu, Xinyuan Wang, Pengliang Chi, Chong Chen, Ting Niu et al. · 2022 · Oncogene
- Discovery and identification of a novel small molecule BCL-2 inhibitor that binds to the BH4 domainJingyi Zhou, Ruirui Yang, Jie Chang, Jia Song, Zisheng Fan, Yinghui Zhang, Cheng-hao Lu, Hualiang Jiang, Ming-yue Zheng, Sulin Zhang · 2022 · Acta Pharmacologica Sinica
- AML under the Scope: Current Strategies and Treatment Involving FLT3 Inhibitors and Venetoclax-Based RegimensSzymon Milnerowicz, Julia Milnerowicz, Paulina Skowera, Magdalena Stelmach, Monika Lejman · 2023 · International Journal of Molecular Sciences
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