Cited by 5,282Nanoparticle-Based Drug DeliveryAdvanced Drug Delivery SystemsRNA Interference and Gene Delivery

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Recent advances with liposomes as pharmaceutical carriers

Torchilin, Vladimir P.·2005·Nature Reviews Drug Discovery

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Abstract

Liposomes - microscopic phospholipid bubbles with a bilayered membrane structure - have received a lot of attention during the past 30 years as pharmaceutical carriers of great potential. More recently, many new developments have been seen in the area of liposomal drugs - from clinically approved products to new experimental applications, with gene delivery and cancer therapy still being the principal areas of interest. For further successful development of this field, promising trends must be identified and exploited, albeit with a clear understanding of the limitations of these approaches.

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Authors: Torchilin, V. P.
Affiliations: Northeastern University (US)
Corresponding author: Torchilin, Vladimir P.
ORCID: Torchilin, Vladimir P.
Venue: Nature Reviews Drug Discovery
Publisher: Springer Science and Business Media LLC
Published: 2005-02
Volume: 4
Issue: 2
Pages: 145-160
ISSN: 1474-1776 (ISSN-L)
1474-1784
DOI: 10.1038/nrd1632
OpenAlex: W2061510929
Cited by: 5,282
References: 210
Citations by year: 2026: 183 · 2025: 227 · 2024: 217 · 2023: 222 · 2022: 284 · 2021: 252 · 2020: 311 · 2019: 275 · 2018: 274 · 2017: 302 · 2016: 343 · 2015: 324 · 2014: 368 · 2013: 334 · 2012: 351
FWCI: 7.98
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature Reviews Drug Discovery (publishedVersion)
PubMed (publishedVersion)
Topics: Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Interference and Gene Delivery
Keywords: liposomes, drug carriers, liposomal drugs, gene delivery, cancer therapy, phospholipid bilayers, drug delivery systems
MeSH terms: Animals, Humans, Liposomes, Technology, Pharmaceutical

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