Recent advances with liposomes as pharmaceutical carriers

Cellular uptake of the tat protein from human immunodeficiency virus

Frankel, A. D., & Pabo, C. O. (1988) · Cell · doi:10.1016/0092-8674(88)90263-2 · Cited by 2,782

Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes

Klibanov, A. L., Maruyama, K., Torchilin, V. P., & Huang, L. (1990) · FEBS Letters · doi:10.1016/0014-5793(90)81016-h · Cited by 2,030

Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis

Wadia, J. S., Stan, R. V., & Dowdy, S. F. (2004) · Nature Medicine · doi:10.1038/nm996 · Cited by 1,647

Liposomes: From Physics to Applications

Lasiç, D. D. (1993) · Cited by 1,304

Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties

Moghimi, S. M., & Szebeni, J. (2003) · Progress in Lipid Research · doi:10.1016/s0163-7827(03)00033-x · Cited by 1,228

Cationic liposome-mediated transfection

Felgner, P. L., & RINGOLD, G. M. (1989) · Nature · doi:10.1038/337387a0 · Cited by 989

Folate-mediated delivery of macromolecular anticancer therapeutic agents

Lu, Y. J., & Low, P. S. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00042-x · Cited by 942

Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS

Maeda, H., Sawa, T., & Konno, T. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00309-1 · Cited by 926

TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors

Torchilin, V. P., Rammohan, R., Weissig, V., & Levchenko, T. S. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.151247498 · Cited by 777

Lipid vesicles and other colloids as drug carriers on the skin

Cevc, G. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.10.028 · Cited by 703

Delivery of liposomes into cultured KB cells via folate receptor-mediated endocytosis.

Lee, R., & Low, P. S. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)41848-5 · Cited by 694

Brain drug delivery of small molecules using immunoliposomes

Huwyler, J., Wu, D., & Pardridge, W. M. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.24.14164 · Cited by 660

Liposomes as drug carriers

Fendler, J. H., & Romero, A. (1977) · Life Sciences · doi:10.1016/0024-3205(77)90481-7 · Cited by 656

Role of Membrane Potential and Hydrogen Bonding in the Mechanism of Translocation of Guanidinium-Rich Peptides into Cells

Rothbard, J. B., Jessop, T. C., Lewis, R. S., Murray, B. A., & Wender, P. A. (2004) · Journal of the American Chemical Society · doi:10.1021/ja0482536 · Cited by 642

Pharmacokinetics of stealth versus conventional liposomes: effect of dose

Allen, T. M., & Hansen, C. (1991) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(91)90201-i · Cited by 589

Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy

Gabizón, A. (2001) · Cancer Investigation · doi:10.1081/cnv-100103136 · Cited by 568

Liposomes

Torchilin, V. P., & Weissig, V. (2003) · doi:10.1093/oso/9780199636556.001.0001 · Cited by 565

Delivery of macromolecules into living cells: a method that exploits folate receptor endocytosis.

Leamon, C. P., & Low, P. S. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.13.5572 · Cited by 558

Liposomes for photodynamic therapy

Derycke, A. (2003) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.07.014 · Cited by 512

On the formulation of pH-sensitive liposomes with long circulation times

Simões, S. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.10.038 · Cited by 485

Which polymers can make nanoparticulate drug carriers long-circulating?

Torchilin, V. P., & Trubetskoy, V. S. (1995) · Advanced Drug Delivery Reviews · doi:10.1016/0169-409x(95)00022-y · Cited by 480

Poly(ethylene glycol) on the liposome surface: on the mechanism of polymer-coated liposome longevity

Torchilin, V. P., Omelyanenko, V. G., Papisov, M. I., Bogdanov, A. A., Jr., Trubetskoy, V. S., Herron, J. N., & Gentry, C. A. (1994) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(94)90003-5 · Cited by 466

Tumor cell targeting of liposome-entrapped drugs with phospholipid-anchored folic acid–PEG conjugates

Gabizon, A. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2004.01.011 · Cited by 464

Liposomes in Drug Delivery

Gregoriadis, G. C., & Florence, A. T. (1993) · Drugs · doi:10.2165/00003495-199345010-00003 · Cited by 453

Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome–DNA complexes

Torchilin, V. P., Levchenko, T. S., Rammohan, R., Volodina, N., Papahadjopoulos‐Sternberg, B., & D’Souza, G. G. M. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0435906100 · Cited by 419

Medical Applications of Liposomes

(1998) · Elsevier eBooks · doi:10.1016/b978-0-444-82917-7.x5000-5 · Cited by 418

New, highly efficient formulation of diclofenac for the topical, transdermal administration in ultradeformable drug carriers, Transfersomes

Cevc, G., & Blume, G. (2001) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(01)00369-8 · Cited by 405

Structures of lipid–DNA complexes: supramolecular assembly and gene delivery

Safinya, C. R. (2001) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(00)00230-x · Cited by 371

Liposomes to target the lymphatics by subcutaneous administration

Oussoren, C. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00154-5 · Cited by 343

Tumor targeting using anti-her2 immunoliposomes

Park, J. W., Kirpotin, D. B., Hong, K., Shalaby, R., Shao, Y., Nielsen, U. B., Marks, J. D., Papahadjopoulos, D., & Benz, C. C. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00315-7 · Cited by 341

Liposome clearance in mice: the effect of a separate and combined presence of surface charge and polymer coating

Levchenko, T. S., Rammohan, R., Lukyanov, A. N., Whiteman, K. R., & Torchilin, V. P. (2002) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(02)00129-1 · Cited by 332

Molecular mechanism of the lipid vesicle longevity in vivo

Blume, G., & Cevc, G. (1993) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(93)90351-y · Cited by 314

Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin

Schiffelers, R. M. (2003) · Journal of Controlled Release · doi:10.1016/s0168-3659(03)00240-2 · Cited by 307

Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells

Mamot, C., Drummond, D. C., Greiser, U., Hong, K., Kirpotin, D. B., Marks, J. D., & Park, J. W. (2004) · The Women s Oncology Review · doi:10.3109/14733400410001727592 · Cited by 298

Tumor-targeted liposomes: doxorubicin-loaded long-circulating liposomes modified with anti-cancer antibody

Lukyanov, A. N., ElBayoumi, T. A., Chakilam, A. R., & Torchilin, V. P. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.08.007 · Cited by 294

Cationic liposome-mediated delivery of siRNAs in adult mice

Sioud, M., & Sørensen, D. R. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.11.057 · Cited by 287

Specific targeting with poly(ethylene glycol)-modified liposomes: coupling of homing devices to the ends of the polymeric chains combines effective target binding with long circulation times

Blume, G., Cevc, G., Crommelin, M. D. J. A., Bakker‐Woudenberg, I. A. J. M., Kluft, C., & Storm, G. (1993) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(93)90039-3 · Cited by 282

p-Nitrophenylcarbonyl-PEG-PE-liposomes: fast and simple attachment of specific ligands, including monoclonal antibodies, to distal ends of PEG chains via p-nitrophenylcarbonyl groups

Torchilin, V. P., Levchenko, T. S., Lukyanov, A. N., Khaw, B., Klibanov, A. L., Rammohan, R., Samokhin, G. P., & Whiteman, K. R. (2001) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2728(01)00165-7 · Cited by 271

Transferrin-Modified Liposomes Equipped with a pH-Sensitive Fusogenic Peptide: An Artificial Viral-like Delivery System

Kakudo, T., Chaki, S., Futaki, S., Nakase, I., Akaji, K., Kawakami, T., Maruyama, K., Kamiya, H., & Harashima, H. (2004) · Biochemistry · doi:10.1021/bi035802w · Cited by 269

Design of liposomal aerosols for improved delivery of rifampicin to alveolar macrophages

Vyas, S. P., Kannan, M., Jain, S., Mishra, V. K., & Singh, P. (2003) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2003.08.017 · Cited by 262

Liposomes Bearing Polyethyleneglycol-Coupled Transferrin with Intracellular Targeting Property to the Solid Tumors In Vivo

Ishida, O., Maruyama, K., Tanahashi, H., Iwatsuru, M., Sasaki, K., Eriguchi, M., & Yanagië, H. (2001) · Pharmaceutical Research · doi:10.1023/a:1010960900254 · Cited by 258

Controlling liposome blood clearance by surface-grafted polymers

Woodle, M. C. (1998) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(97)00136-1 · Cited by 246

Systemic tumor-targeted gene delivery by anti-transferrin receptor scFv-immunoliposomes.

Xu, L., Huang, C., Huang, W., Tang, W., Rait, A. S., Yin, Y. Z., Cruz, I., Xiang, L., Pirollo, K. F., & Chang, E. H. (2002) · PubMed · Cited by 243

Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs.

Sapra, P., & Allen, T. M. (2002) · PubMed · Cited by 242

Translocation of Liposomes into Cancer Cells by Cell-Penetrating Peptides Penetratin and Tat: A Kinetic and Efficacy Study

Tseng, Y., Liu, J., & Hong, R. (2002) · Molecular Pharmacology · doi:10.1124/mol.62.4.864 · Cited by 241

Loading mitomycin C inside long circulating hyaluronan targeted nano‐liposomes increases its antitumor activity in three mice tumor models

Peer, D., & Margalit, R. (2003) · International Journal of Cancer · doi:10.1002/ijc.11615 · Cited by 229

Targeted accumulation of polyethylene glycol‐coated immunoliposomes in infarcted rabbit myocardium

Torchilin, V. P., Klibanov, A. L., Huang, L., O'Donnell, S. M., Nossiff, N. D., & Khaw, B. (1992) · The FASEB Journal · doi:10.1096/fasebj.6.9.1612296 · Cited by 216

Intracellular targeting therapy of cisplatin‐encapsulated transferrin‐polyethylene glycol liposome on peritoneal dissemination of gastric cancer

Iinuma, H., Maruyama, K., Okinaga, K., Sasaki, K., Sekine, T., Ishida, O., Ogiwara, N., Johkura, K., & Yonemura, Y. (2002) · International Journal of Cancer · doi:10.1002/ijc.10242 · Cited by 216

“Smart” delivery of antisense oligonucleotides by anionic pH-sensitive liposomes

Fattal, E. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.10.037 · Cited by 216

Amphiphilic poly-N-vinylpyrrolidones:

Torchilin, V. P., Levchenko, T. S., Whiteman, K. R., Yaroslavov, A. A., Tsatsakis, A. M., Rizos, A. K., Michailova, E. V., & Shtilman, M. I. (2001) · Biomaterials · doi:10.1016/s0142-9612(01)00050-3 · Cited by 214

Multicenter study of pegylated liposomal doxorubicin in patients with cutaneous T‐cell lymphoma

Wollina, U., Dummer, R., Brockmeyer, N. H., Konrad, H., Busch, J., Kaatz, M., Knopf, B., Koch, H., & Hauschild, A. (2003) · Cancer · doi:10.1002/cncr.11593 · Cited by 214

Virosomes: evolution of the liposome as a targeted drug delivery system

Kaneda, Y. (2000) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(00)00069-7 · Cited by 208

Evaluation of circulation profiles of liposomes coated with hydrophilic polymers having different molecular weights in rats

Takeuchi, H., Kojima, H., Yamamoto, H., & Kawashimà, Y. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00368-6 · Cited by 205

Strategy for the treatment of acute myelogenous leukemia based on folate receptor β–targeted liposomal doxorubicin combined with receptor induction using all-trans retinoic acid

Pan, X. Q., Zheng, X., Shi, G., Wang, H., Ratnam, M., & Lee, R. J. (2002) · Blood · doi:10.1182/blood.v100.2.594 · Cited by 199

New Detachable Poly(ethylene glycol) Conjugates: Cysteine-Cleavable Lipopolymers Regenerating Natural Phospholipid, Diacyl Phosphatidylethanolamine

Zalipsky, S., Qazen, M. M., Walker, J. A., Mullah, N. N., Quinn, Y. P., & Huang, S. K. (1999) · Bioconjugate Chemistry · doi:10.1021/bc990031n · Cited by 198

Efficient intracellular drug and gene delivery using folate receptor-targeted pH-sensitive liposomes composed of cationic/anionic lipid combinations

Shi, G., Guo, W., Stephenson, S. M., & Lee, R. J. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00017-2 · Cited by 192

In vivo monitoring of tissue pharmacokinetics of liposome/drug using MRI: Illustration of targeted delivery

Viglianti, B. L., Abraham, S. A., Michelich, C. R., Yarmolenko, P., MacFall, J. R., Bally, M. B., & Dewhirst, M. W. (2004) · Magnetic Resonance in Medicine · doi:10.1002/mrm.20074 · Cited by 192

In Vivo Characteristics of Cationic Liposomes as Delivery Vectors for Gene Therapy

Audouy, S. A. L., de Leij, L. F. M. H., Hoekstra, D., & Molema, G. (2002) · Pharmaceutical Research · doi:10.1023/a:1020989709019 · Cited by 189

Lectin-bearing Polymerized Liposomes as Potential Oral Vaccine Carriers

Chen, H., Torchilin, V. P., & Langer, R. (1996) · Pharmaceutical Research · doi:10.1023/a:1016030202104 · Cited by 186

Liposomal delivery of antigen to human dendritic cells

Copland, M. J., Baird, M. A., Rades, T., McKenzie, J. L., Becker, B., Reck, F., Tyler, P. C., & Davies, N. M. (2003) · Vaccine · doi:10.1016/s0264-410x(02)00536-4 · Cited by 185

Folate targeting of haptens to cancer cell surfaces mediates immunotherapy of syngeneic murine tumors

Low, P. S. (2002) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-002-0266-6 · Cited by 185

Oral colon-specific drug delivery for bee venom peptide: development of a coated calcium alginate gel beads-entrapped liposome

Liu, X., Dawei, C., Li-ping, X., & Rongqing, Z. (2003) · Journal of Controlled Release · doi:10.1016/j.jconrel.2003.08.019 · Cited by 184

Liposomes as Tools in Basic Research and Industry (1994)

(2017) · CRC Press eBooks · doi:10.1201/9780203713259 · Cited by 181

Folate-Liposome-Mediated Antisense Oligodeoxynucleotide Targeting to Cancer Cells: Evaluation in Vitro and in Vivo

Leamon, C. P., Cooper, S. R., & Hardee, G. E. (2003) · Bioconjugate Chemistry · doi:10.1021/bc020089t · Cited by 181

From Conventional to Stealth Liposomes a new Frontier in Cancer Chemotherapy

Cattel, L., Ceruti, M., & Dosio, F. (2003) · Tumori Journal · doi:10.1177/030089160308900302 · Cited by 175

Functional Characterization of an Endosome-disruptive Peptide and Its Application in Cytosolic Delivery of Immunoliposome-entrapped Proteins

Mastrobattista, E., Koning, G. A., van Bloois, L., Filipe, A. C. S., Jiskoot, W., & Storm, G. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m200429200 · Cited by 173

Folate-targeted, cationic liposome-mediated gene transfer into disseminated peritoneal tumors

Reddy, J. A., Abburi, C., Hofland, H. E. J., Howard, S. J., VLAHOV, I. R., Wils, P., & Leamon, C. P. (2002) · Gene Therapy · doi:10.1038/sj.gt.3301833 · Cited by 173

Cell-specific delivery of genes with glycosylated carriers

Hashida, M. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00209-5 · Cited by 171

A Novel Liposomal Bupivacaine Formulation to Produce Ultralong-Acting Analgesia

Grant, G. J., Barenholz, Y., Bolotin, E. M., Bansinath, M., Turndorf, H., Piskoun, B., & Davidson, E. M. (2004) · Anesthesiology · doi:10.1097/00000542-200407000-00021 · Cited by 170

Liposomes with phosphatidylethanol as a carrier for oral delivery of insulin: studies in the rat

Kisel, M. A., Kulik, L. N., Tsybovsky, I. S., Vlasov, A. P., Vorobyov, M., Kholodova, E., & Zabarovskaya, Z. V. (2001) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(01)00579-8 · Cited by 161

Application of surface‐coated liposomes for oral delivery of peptide: Effects of coating the liposome's surface on the GI transit of insulin

Iwanaga, K., Ono, S., Narioka, K., Kakemi, M., Morimoto, K., Yamashita, S., Namba, Y., & Oku, N. (1999) · Journal of Pharmaceutical Sciences · doi:10.1021/js980235x · Cited by 153

Monoclonal Antibody to Cardiac Myosin: Imaging of Experimental Myocardial Infarction

Khaw, B., Mattis, J. A., Melincoff, G. A., Strausś, H. W., Gold, H. K., & Haber, E. (1984) · Hybridoma · doi:10.1089/hyb.1984.3.11 · Cited by 152

Polyethylene Glycol-Modified Liposome-Encapsulated Hemoglobin: A Long Circulating Red Cell Substitute

Phillips, W. T., Klipper, R. W., Awasthi, V., Rudolph, A. S., Cliff, R. O., Kwasiborski, V., & Goins, B. (1999) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38004-8 · Cited by 149

A Novel Family of l -Amino Acid-Based Biodegradable Polymer−Lipid Conjugates for the Development of Long-Circulating Liposomes with Effective Drug-Targeting Capacity

Metselaar, J. M., de Bruin, P., de Boer, L. W. T., de Vringer, T., Snel, C. J., Oussoren, C., Wauben, M. H. M., Crommelin, D. J. A., Storm, G., & Hennink, W. E. (2003) · Bioconjugate Chemistry · doi:10.1021/bc0340363 · Cited by 149

Factors governing the in vivo tissue uptake of transferrin-coupled polyethylene glycol liposomes in vivo

Hatakeyama, H., Akita, H., Maruyama, K., Suhara, T., & Harashima, H. (2004) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2004.05.025 · Cited by 147

Virosome-mediated delivery of protein antigens to dendritic cells

Bungener, L. B., Serre, K., Bijl, L., Leserman, L., Wilschut, J., Daemen, T., & Machy, P. (2002) · Vaccine · doi:10.1016/s0264-410x(02)00103-2 · Cited by 147

Surface modification of liposomes for selective cell targeting in cardiovascular drug delivery

Lestini, B. J., Sagnella, S. M., Xu, Z. C., Shive, M. S., Richter, N. J., Johnsamuel, J., Case, A. J., Kottke‐Marchant, K., Anderson, J. M., & Marchant, R. E. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00505-3 · Cited by 146

A novel pH-sensitive liposome formulation containing oleyl alcohol

Sudimack, J. J., Guo, W., Tjarks, W., & Lee, R. J. (2002) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(02)00399-1 · Cited by 143

Long Circulating Liposomes: Old Drugs, New Therapeutics

Woodle, M. C., & Storm, G. (1998) · Springer eBooks · doi:10.1007/978-3-662-22115-0 · Cited by 137

Single‐Dose Liposomal Amphotericin B in the Treatment of Visceral Leishmaniasis in India: A Multicenter Study

Sundar, S., Jha, T. K., Thakur, C. P., Mishra, M., Singh, V. P., & Buffels, R. (2003) · Clinical Infectious Diseases · doi:10.1086/377542 · Cited by 134

Poly(ethylene glycol)-Conjugation and Deoxygenation Enable Long-Term Preservation of Hemoglobin-Vesicles as Oxygen Carriers in a Liquid State

Sakai, H., Tomiyama, K.-I., Sou, K., Takeoka, S., & Tsuchida, E. (2000) · Bioconjugate Chemistry · doi:10.1021/bc990173h · Cited by 129

Evaluation of systemic chemotherapy with magnetic liposomal doxorubicin and a dipole external electromagnet

Nobuto, H., Sugita, T., Kubo, T., Shimose, S., Yasunaga, Y., Murakami, T., & Ochi, M. (2004) · International Journal of Cancer · doi:10.1002/ijc.20035 · Cited by 126

Polymeric Contrast Agents for Medical Imaging

Torchilin, V. P. (2000) · Current Pharmaceutical Biotechnology · doi:10.2174/1389201003378960 · Cited by 125

Liposomes as targetable drug carriers.

Torchilin, V. P. (1985) · PubMed · Cited by 125

Characterization of a novel pH-sensitive peptide that enhances drug release from folate-targeted liposomes at endosomal pHs

Turk, M. J., Reddy, J. A., Chmielewski, J. A., & Low, P. S. (2002) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(01)00441-2 · Cited by 123

Phase II Trial Of Pegylated-liposomal Doxorubicin (Doxil™) In Sarcoma*

Skubitz, K. M. (2003) · Cancer Investigation · doi:10.1081/cnv-120016412 · Cited by 122

Novel chondroitin sulfate-binding cationic liposomes loaded with cisplatin efficiently suppress the local growth and liver metastasis of tumor cells in vivo.

Lee, C. M., Tanaka, T. T., Murai, T., Kondo, M., Kimura, J., Su, W., Kitagawa, T., Ito, T., Matsuda, H., & Miyasaka, M. (2002) · PubMed · Cited by 121

Percutaneous Tumor Ablation: Increased Necrosis with Combined Radio-frequency Ablation and Intravenous Liposomal Doxorubicin in a Rat Breast Tumor Model

Goldberg, S. N., Girnan, G. D., Lukyanov, A. N., Ahmed, M., Monsky, W. L., Gazelle, G. S., Huertas, J. C., Stuart, K. E., Jacobs, T. W., Torchilin, V. P., et al. (2002) · Radiology · doi:10.1148/radiol.2223010861 · Cited by 120

VIP grafted sterically stabilized liposomes for targeted imaging of breast cancer: in vivo studies

Dagar, S. (2003) · Journal of Controlled Release · doi:10.1016/s0168-3659(03)00242-6 · Cited by 118

Antitumor Activity of Folate Receptor-Targeted Liposomal Doxorubicin in a KB Oral Carcinoma Murine Xenograft Model

Pan, X. Q., Wang, H., & Lee, R. J. (2003) · Pharmaceutical Research · doi:10.1023/a:1022656105022 · Cited by 115

Pegylated Liposomal Doxorubicin in the Treatment of Breast Cancer

O’Shaughnessy, J. (2003) · Clinical Breast Cancer · doi:10.3816/cbc.2003.n.037 · Cited by 115

Pegylated Liposomal Doxorubicin (Doxil ® ) for Metastatic Breast Cancer: The Cancer Research Network, Inc., Experience

Perez, A., Domenech, G. H., Frankel, C., & Vogel, C. L. (2002) · Cancer Investigation · doi:10.1081/cnv-120014883 · Cited by 114

Targeting of the photocytotoxic compound AlPcS4 to hela cells by transferrin conjugated peg‐liposomes

Gijsens, A., Derycke, A., Missiaen, L., Vos, D. E. D., Huwyler, J., Eberlé, A. N., & de Witte, P. A. M. (2002) · International Journal of Cancer · doi:10.1002/ijc.10548 · Cited by 114

Stability of liposomal formulations in physiological conditions for oral drug delivery

Taira, M. C., Chiaramoni, N. S., Pecuch, K. M., & Alonso-Romanowski, S. (2004) · Drug Delivery · doi:10.1080/10717540490280769 · Cited by 113

Hemoglobin-vesicles suspended in recombinant human serum albumin for resuscitation from hemorrhagic shock in anesthetized rats*

Sakai, H., Masada, Y., Horinouchi, H., Yamamoto, M., Ikeda, E., Takeoka, S., Kobayashi, K., & Tsuchida, E. (2004) · Critical Care Medicine · doi:10.1097/01.ccm.0000109774.99665.22 · Cited by 109

Liposomes as delivery agents for medical imaging

Torchilin, V. P. (1996) · Molecular Medicine Today · doi:10.1016/1357-4310(96)88805-8 · Cited by 109

Antibody targeted gene transfer to endothelium

Tan, P., Manunta, M., Ardjomand, N., Xue, S., Larkin, F., Haskard, D. O., Taylor, K. M., & George, A. J. T. (2002) · The Journal of Gene Medicine · doi:10.1002/jgm.358 · Cited by 108

In vivo antigen loading and activation of dendritic cells via a liposomal peptide vaccine mediates protective antiviral and anti-tumour immunity

Ludewig, B., Barchiesi, F., Pericin, M., Zinkernagel, R. M., Hengartner, H., & Schwendener, R. A. (2000) · Vaccine · doi:10.1016/s0264-410x(00)00163-8 · Cited by 108

Polyethylene glycol-coated liposomes for oral delivery of recombinant human epidermal growth factor

Li, H. (2003) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(03)00158-3 · Cited by 102

Neutral and Anionic Liposome-Encapsulated Hemoglobin: Effect of Postinserted Poly(ethylene glycol)-distearoylphosphatidylethanolamine on Distribution and Circulation Kinetics

Awasthi, V., Garcia, D., Klipper, R. W., Goins, B., & Phillips, W. T. (2004) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.060228 · Cited by 101

9-Nitrocamptothecin liposome aerosol treatment of melanoma and osteosarcoma lung metastases in mice.

Koshkina, N. V., Kleinerman, E. S., Waidrep, C., Jia, S.-F., Worth, L. L., Gilbert, B. E., & Knight, V. (2000) · PubMed · Cited by 101

Delivery of lipids and liposomal proteins to the cytoplasm and Golgi of antigen-presenting cells

Rao, M., & Alving, C. R. (2000) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(99)00064-2 · Cited by 99

Liposomal Formulations of Synthetic MUC1 Peptides: Effects of Encapsulation versus Surface Display of Peptides on Immune Responses

Guan, H. H., Budzynski, W. A., Koganty, R. R., Krantz, M. J., Reddish, M. A., Rogers, J. A., Longenecker, B. M., & Samuel, J. (1998) · Bioconjugate Chemistry · doi:10.1021/bc970183n · Cited by 96

Virosomal adjuvanted antigen delivery systems

Moser, C., Metcalfe, I. C., & Viret, J. (2003) · Expert Review of Vaccines · doi:10.1586/14760584.2.2.189 · Cited by 94

Liposomes and disaccharides as carriers in spray-dried powder formulations of superoxide dismutase

Lo, Y., Tsai, J., & Kuo, J.-H. S. (2003) · Journal of Controlled Release · doi:10.1016/j.jconrel.2003.09.019 · Cited by 93

POLY(HPMA)-COATED LIPOSOMES DEMONSTRATE PROLONGED CIRCULATION IN MICE

Whiteman, K. R., Šubr, V., Ulbrich, K., & Torchilin, V. P. (2001) · Journal of Liposome Research · doi:10.1081/lpr-100108459 · Cited by 93

Efficacy of liposomal budesonide in experimental asthma

Konduri, K. S., Nandedkar, S. D., Düzgüneş, N., Suzara, V. V., Artwohl, J. E., Bunte, R. M., & Gangadharam, P. R. (2003) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2003.104 · Cited by 93

Hypoglycemic efficacy of chitosan-coated insulin liposomes after oral administration in mice.

Zheng-hongWU, Qi-nengPING, YiWEI, & Jia-mingLAI (2004) · PubMed · Cited by 92

186Re-liposome labeling using 186Re-SNS/S complexes: in vitro stability, imaging, and biodistribution in rats.

Bao, A., Goins, B., Klipper, R. W., Negrete, G. R., & Phillips, W. T. (2003) · PubMed · Cited by 91

The Potential of Liposomes in Oral Drug Delivery

Rogers, J. A., & Anderson, K. E. (1998) · Critical Reviews in Therapeutic Drug Carrier Systems · doi:10.1615/critrevtherdrugcarriersyst.v15.i5.10 · Cited by 91

Thrombolytic Treatment with Tissue-type Plasminogen Activator (t-PA) Containing Liposomes in Rabbits: a Comparison with Free t-PA

Heeremans, J. L. M., Prevost, R., Bekkers, M., Łoś, P., Emeis, J. J., Kluft, C., & Crommelin, D. J. A. (1995) · Thrombosis and Haemostasis · doi:10.1055/s-0038-1653802 · Cited by 91

Freeze-Drying of Liposomes: Theory and Practice

van Winden, E. C. A. (2003) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(03)67008-4 · Cited by 90

The effects of supplementation with ?-tocopherol and ?-carotene on the incidence and mortality of carcinoma of the pancreas in a randomized, controlled trial

Rautalahti, M., Virtamo, J. R. K., Taylor, P. R., Heinonen, O. P., Albanes, D., Haukka, J. K., Edwards, B. K., Kärkkäinen, P., Stolzenberg‐Solomon, R. Z., & Huttunen, J. K. (1999) · Cancer · doi:10.1002/(sici)1097-0142(19990701)86:1 · Cited by 90

Serum-stable and long-circulating, PEGylated, pH-sensitive liposomes

Roux, E., Passirani, C., Scheffold, S., Benoît, J., & Leroux, J. (2003) · Journal of Controlled Release · doi:10.1016/j.jconrel.2003.10.024 · Cited by 86

Application of polyethyleneglycol (PEG)-modified liposomes for oral vaccine: effect of lipid dose on systemic and mucosal immunity

Minato, S., Iwanaga, K., Kakemi, M., Yamashita, S., & Oku, N. (2003) · Journal of Controlled Release · doi:10.1016/s0168-3659(03)00093-2 · Cited by 84

A phase II study of liposomal lurtotecan (OSI-211) in patients with topotecan resistant ovarian cancer

Seiden, M. V., Muggia, F. M., Astrow, A., Matulonis, U. A., Campos, S., Roche, M. R., Sivret, J., Rusk, J., & Barrett, E. (2004) · Gynecologic Oncology · doi:10.1016/j.ygyno.2003.12.037 · Cited by 84

Transferrin-mediated targeting of hypericin embedded in sterically stabilized PEG-liposomes

Derycke, A., & de Witte, P. A. M. (2002) · International Journal of Oncology · doi:10.3892/ijo.20.1.181 · Cited by 83

Liposomes: From the Bench to the Bed

Crommelin, D. J. A., & Storm, G. (2003) · Journal of Liposome Research · doi:10.1081/lpr-120017488 · Cited by 81

Cationic Liposome-Mediated Gene Delivery In vivo

Templeton, N. S. (2002) · Bioscience Reports · doi:10.1023/a:1020142823595 · Cited by 81

Sterically stabilized liposomes in cancer therapy and gene delivery.

Lasiç, D. D., Jj, V., & Working, P. K. (1999) · PubMed · Cited by 81

Open, Randomized Study to Compare the Immunogenicity and Reactogenicity of an Influenza Split Vaccine with an MF59-Adjuvanted Subunit Vaccine and a Virosome-Based Subunit Vaccine in Elderly

Ruf, B., Colberg, K., Frick, M., & Preusche, A. (2004) · Infection · doi:10.1007/s15010-004-3204-z · Cited by 80

Liposomal Delivery of CTL Epitopes to Dendritic Cells

Chikh, G., & Schutze-Redelmeier, M.-P. M. (2002) · Bioscience Reports · doi:10.1023/a:1020151025412 · Cited by 79

Plug and seal: Prevention of hypoxic cardiocyte death by sealing membrane lesions with antimyosin-liposomes

Khaw, B., Torchilin, V. P., Vural, İ., & Narula, J. (1995) · Nature Medicine · doi:10.1038/nm1195-1195 · Cited by 79

Targeted systemic chemotherapy using magnetic liposomes with incorporated adriamycin for osteosarcoma in hamsters.

Kubo, T., Sugita, T., Shimose, S., Nitta, Y., Ikuta, Y., & Murakami, T. (2001) · International Journal of Oncology · doi:10.3892/ijo.18.1.121 · Cited by 79

Transdermal Delivery of Pergolide from Surfactant-Based Elastic and Rigid Vesicles: Characterization and in Vitro Transport Studies

Honeywell‐Nguyen, P. L., Frederik, P. M., Bomans, P. H. H., Junginger, H. E., & Bouwstra, J. A. (2002) · Pharmaceutical Research · doi:10.1023/a:1016466406176 · Cited by 78

A Novel Liposome Radiolabeling Method Using 99mTc-“SNS/S” Complexes: In Vitro and In Vivo Evaluation

Bao, A., Goins, B., Klipper, R. W., Negrete, G. R., Mahindaratne, M. P. D., & Phillips, W. T. (2003) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.10441 · Cited by 78

Biological characterization of L -asparaginase liposomal formulations

Gaspar, M. M., Pérez-Soler, R., & Cruz, M. E. M. (1996) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s002800050497 · Cited by 75

Phospholipid Deformable Vesicles for Buccal Delivery of Insulin.

Yang, T.-Z., Wang, X., Yan, X., & Zhang, Q. (2002) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.50.749 · Cited by 75

Folate receptor targeted delivery of liposomal daunorubicin into tumor cells.

Ni, S., Stephenson, S. M., & Lee, R. J. (2002) · PubMed · Cited by 75

Long-circulating gadolinium-loaded liposomes: potential use for magnetic resonance imaging of the blood pool

Weissig, V., Babich, J., & Torchilin, V. P. (2000) · Colloids and Surfaces B Biointerfaces · doi:10.1016/s0927-7765(99)00155-1 · Cited by 74

Intracellular target for photosensitization in cancer antiangiogenic photodynamic therapy mediated by polycation liposome

Takeuchi, Y., Ichikawa, K., Yonezawa, S., Kurohane, K., Koishi, T., Nango, M., Namba, Y., & Oku, N. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.03.030 · Cited by 72

Antibody titres after primary and booster vaccination of infants and young children with a virosomal hepatitis A vaccine (Epaxal®)

Usonis, V., Bakasénas, V., Valentelis, R., Katiliene, G., Vidzeniene, D., & Herzog, C. (2003) · Vaccine · doi:10.1016/s0264-410x(03)00509-7 · Cited by 72

Targeting of post-ischemic cerebral endothelium in rat by liposomes bearing polyethylene glycol-coupled transferrin

Omori, N., Maruyama, K., Jin, G., Wang, S., Hamakawa, Y., Sato, K., NAGANO, I., Shoji, M., & Abe, K. (2003) · Neurological Research · doi:10.1179/016164103101201508 · Cited by 72

Novel Method of Greatly Enhanced Delivery of Liposomes to Lymph Nodes

Phillips, W. T., Klipper, R. W., & Goins, B. (2000) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38903-7 · Cited by 71

THE NEXT GENERATION OF LIPOSOME DELIVERY SYSTEMS: RECENT EXPERIENCE WITH TUMOR-TARGETED, STERICALLY-STABILIZED IMMUNOLIPOSOMES AND ACTIVE-LOADING GRADIENTS

Abra, R. M., Bankert, R. B., Chen, F., Egilmez, N. K., Huang, K., Saville, R., Slater, J. L., Sugano, M., & Yokota, S. J. (2002) · Journal of Liposome Research · doi:10.1081/lpr-120004770 · Cited by 69

Microvascular responses to hemodilution with Hb vesicles as red blood cell substitutes: influence of O 2 affinity

Sakai, H., Tsai, A. G., Rohlfs, R. J., Hara, H., Takeoka, S., Tsuchida, E., & Intaglietta, M. (1999) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1999.276.2.h553 · Cited by 69

Delivery of Protein Antigens to the Immune System by Fusion-Active Virosomes: A Comparison with Liposomes and ISCOMs

Bungener, L. B., Huckriede, A. L. W., Wilschut, J., & Daemen, T. (2002) · Bioscience Reports · doi:10.1023/a:1020198908574 · Cited by 66

Long-circulating sterically stabilized liposomes as carriers of agents for treatment of infection or for imaging infectious foci

Bakker‐Woudenberg, I. A. J. M. (2002) · International Journal of Antimicrobial Agents · doi:10.1016/s0924-8579(02)00021-3 · Cited by 66

Liposomal doxorubicin and weekly paclitaxel in the treatment of metastatic breast cancer

Schwonzen, M., Kurbacher, C. M., & Mallmann, P. K. (2000) · Anti-Cancer Drugs · doi:10.1097/00001813-200010000-00002 · Cited by 66

Treatment of murine L1210 lymphoid leukemia and melanoma B16 with lipophilic cytosine arabinoside prodrugs incorporated into unilamellar liposomes

Rubas, W., Supersaxo, A., Weder, H. G., Hartmann, H. R., Hengartner, H., Schott, H. N., & Schwendener, R. A. (1986) · International Journal of Cancer · doi:10.1002/ijc.2910370123 · Cited by 66

Phase II study of pegylated liposomal doxorubicin (Caelyx™) as induction chemotherapy for patients with squamous cell cancer of the head and neck

Harrington, K. J., Lewanski, C. R., Northcote, A. D., Whittaker, J., Peters, A. M., Vile, R. G., & Stewart, J. S. W. (2001) · European Journal of Cancer · doi:10.1016/s0959-8049(01)00216-7 · Cited by 65

Polycation liposome-mediated gene transfer in vivo

Matsuura, M., Yamazaki, Y., Sugiyama, M., Kondo, M., Ori, H., Nango, M., & Oku, N. (2003) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(03)00109-3 · Cited by 65

Antiangiogenic photodynamic therapy (PDT) using Visudyne causes effective suppression of tumor growth

Ichikawa, K., Takeuchi, Y., Yonezawa, S., Hikita, T., Kurohane, K., Namba, Y., & Oku, N. (2003) · Cancer Letters · doi:10.1016/j.canlet.2003.10.001 · Cited by 65

Liposome targeting to tumors using vitamin and growth factor receptors

Drummond, D. C., Hong, K., Park, J. W., Benz, C. C., & Kirpgtin, D. B. (2000) · Vitamins and hormones · doi:10.1016/s0083-6729(00)60022-5 · Cited by 64

Cyclosporin A Aerosol Improves the Anticancer Effect of Paclitaxel Aerosol in Mice

Koshkina, N. V., Golunski, E., Roberts, L., Gilbert, B. E., & Knight, V. (2004) · Journal of Aerosol Medicine · doi:10.1089/089426804322994415 · Cited by 64

Influenza virosomes as an efficient system for adjuvanted vaccine delivery

Glück, R., Moser, C., & Metcalfe, I. C. (2004) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.4.7.1139 · Cited by 62

Inhibition of liver metastasis by targeting of immunomodulators using mannosylated liposome carriers

Opanasopit, P., Sakai, M., Nishikawa, M., Kawakami, S., Yamashita, F., & Hashida, M. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00006-8 · Cited by 61

Caelyx®

Johnston, S. R. D., & Gore, M. E. (2001) · European Journal of Cancer · doi:10.1016/s0959-8049(01)00329-x · Cited by 60

In Vitro Aerosol Delivery and Regional Airway Surface Liquid Concentration of a Liposomal Cationic Peptide

Lange, C. F., Hancock, R. E. W., Samuel, J., & Finlay, W. H. (2001) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.1115 · Cited by 60

Lymphatic delivery and pharmacokinetics of methotrexate after intramuscular injection of differently charged liposome-entrapped methotrexate to rats

Kim, C. K., & Han, J. H. (1995) · Journal of Microencapsulation · doi:10.3109/02652049509087256 · Cited by 59

Liposomes Containing Interferon-Gamma as Adjuvant in Tumor Cell Vaccines

van Slooten, M. L., Storm, G., Zoephel, A., Küpcü, Z., Boerman, O. C., Crommelin, D. J. A., Wagner, E., & Kircheis, R. (2000) · Pharmaceutical Research · doi:10.1023/a:1007514424253 · Cited by 58

ATP-loaded liposomes effectively protect mechanical functions of the myocardium from global ischemia in an isolated rat heart model

Verma, D. D., Levchenko, T. S., Bernstein, E. A., & Torchilin, V. P. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2005.08.029 · Cited by 57

Comparison of the quality of protection elicited by toxoid and peptide liposomal vaccine formulations against ricin as assessed by markers of inflammation

Griffiths, G., Phillips, G. J., & Bailey, S. C. (1999) · Vaccine · doi:10.1016/s0264-410x(99)00054-7 · Cited by 56

Anti‐neovascular therapy by liposomal DPP‐CNDAC targeted to angiogenic vessels

Asai, T., Shimizu, K., Kondo, M., Kuromi, K., Watanabe, K., Ogino, K., Taki, T., Shuto, S., Matsuda, A., & Oku, N. (2002) · FEBS Letters · doi:10.1016/s0014-5793(02)02821-1 · Cited by 55

Site-Specific in vivo Targeting of Magnetoliposomes Using Externally Applied Magnetic Field

Babincová, M., Altanerová, V., Lampert, M., Altaner, Č., Machová, E., rámka, M. Š., & Babinec, P. (2000) · Zeitschrift für Naturforschung C · doi:10.1515/znc-2000-3-422 · Cited by 55

A facile method of delivery of liposomes by nebulization

Desai, T. R., Hancock, R. E. W., & Finlay, W. H. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00264-x · Cited by 54

Biodistribution and Computed tomography Blood-Pool Imaging Properties of Polyethylene Glycol-Coated Iopromide-Carrying Liposomes

Sachse, A., LEIKE, J. U., THOMAS SCHNEIDER, Wagner, S., RÖling, G. L., Kŕause, W., & Brandl, M. (1997) · Investigative Radiology · doi:10.1097/00004424-199701000-00007 · Cited by 53

Efficient delivery of DNA to dendritic cells mediated by influenza virosomes

Cusi, M. G., Terrosi, C., Savellini, G. G., Genova, G. D., Zurbriggen, R., & Correale, P. (2003) · Vaccine · doi:10.1016/j.vaccine.2003.08.024 · Cited by 53

Efficient Delivery of Antennapedia Homeodomain Fused to CTL Epitope with Liposomes into Dendritic Cells Results in the Activation of CD8+ T Cells

Chikh, G., Kong, S., Bally, M. B., Meunier, J.-C., & Schutze-Redelmeier, M.-P. M. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.11.6462 · Cited by 53

Potentiality of double liposomes containing salmon calcitonin as an oral dosage form

Yamabe, K., Katō, Y., Onishi, H., & Machida, Y. (2003) · Journal of Controlled Release · doi:10.1016/s0168-3659(03)00160-3 · Cited by 52

Preparation and Evaluation of Lyophilized Iopromide-Carrying Liposomes for Liver Tumor Detection

Sachse, A., LEIKE, J. U., RÖling, G. L., Wagner, S. E., & Kŕause, W. (1993) · Investigative Radiology · doi:10.1097/00004424-199328090-00019 · Cited by 52

Influenza Virosomes in Vaccine Development

Huckriede, A. L. W., Bungener, L. B., Daemen, T., & Wilschut, J. (2003) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(03)73005-5 · Cited by 51

Liposome-entrapped superoxide dismutase reduces ischemia/reperfusion ?oxidative stress? in gerbil brain

Stanimirovic, D. B., Markovic, M., Micic, D. V., Spatz, M., & Mršulja, B. B. (1994) · Neurochemical Research · doi:10.1007/bf00968993 · Cited by 51

Pharmacodynamics of insulin in polyethylene glycol-coated liposomes

Kim, A., Yun, M.-O., Oh, Y., Ahn, W., & Kim, C. (1999) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(98)00408-6 · Cited by 51

Uptake of Long-Circulating Immunoliposomes, Directed Against Colon Adenocarcinoma Cells, by Liver Metastases of Colon Cancer

Kamps, J. A. A. M., Koning, G. A., Velinova, M. J., Morselt, H. W. M., Wilkens, M., Gorter, A., Donga, J., & Scherphof, G. L. (2000) · Journal of drug targeting · doi:10.3109/10611860008997902 · Cited by 49

Targeted delivery system for antisense oligonucleotides: a novel experimental strategy for neuroblastoma treatment

Brignole, C., Pagnan, G., Marimpietri, D., Cosimo, E., Allen, T. M., Ponzoni, M., & Pastorino, F. (2003) · Cancer Letters · doi:10.1016/s0304-3835(03)00107-1 · Cited by 48

Biodistribution of pH-responsive liposomes for MRI and a novel approach to improve the pH-responsiveness

Løkling, K., Fossheim, S. L., Klaveness, J., & Skurtveit, R. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.04.015 · Cited by 47

Immobilized Enzymes in Medicine

Torchilin, V. P. (1991) · Progress in clinical biochemistry and medicine · doi:10.1007/978-3-642-75821-8 · Cited by 46

Transdermal lontophoretic Delivery of Enkephalin Formulated in Liposomes

Vutla, N. B., Betageri, G. V., & Banga, A. K. (1996) · Journal of Pharmaceutical Sciences · doi:10.1021/js950349y · Cited by 45

Liposome-Mediated Targeting of Enzymes to Cancer Cells for Site-Specific Activation of Prodrugs: Comparison with the Corresponding Antibody-Enzyme Conjugate

Fonseca, M. J., Jagtenberg, J. C., Haisma, H. J., & Storm, G. (2003) · Pharmaceutical Research · doi:10.1023/a:1022608321861 · Cited by 45

Liposomal photofrin enhances therapeutic efficacy of photodynamic therapy against the human gastric cancer

Igarashi, A., Konno, H., Tanaka, T., Nakamura, S., Sadzuka, Y., Hirano, T., & Fujise, Y. (2003) · Toxicology Letters · doi:10.1016/s0378-4274(03)00241-8 · Cited by 44

Antiactin-Targeted Immunoliposomes Ameliorate Tissue Plasminogen Activator-Induced Hemorrhage after Focal Embolic Stroke

Asahi, M., Rammohan, R., Sumii, T., Wang, X., Pauw, R. J., Weissig, V., Torchilin, V. P., & Lo, E. H. (2003) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/01.wcb.0000072570.46552.df · Cited by 42

Transferrin-Facilitated Lipofection Gene Delivery Strategy: Characterization of the Transfection Complexes and Intracellular Trafficking

Joshee, N., Bastola, D. R., & Cheng, P. (2002) · Human Gene Therapy · doi:10.1089/10430340260355392 · Cited by 42

Folate receptor-targeted liposomes as possible delivery vehicles for boron neutron capture therapy.

Stephenson, S. M., Yang, W., Stevens, P. J., Tjarks, W., Barth, R. F., & Lee, R. J. (2003) · PubMed · Cited by 42

Effect of Hb-Encapsulation with Vesicles on H2O2 Reaction and Lipid Peroxidation

Takeoka, S., Teramura, Y., Atoji, T., & Tsuchida, E. (2002) · Bioconjugate Chemistry · doi:10.1021/bc025546k · Cited by 37

Surface-modified liposomes in gamma- and MR-imaging

Torchilin, V. P. (1997) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(96)00472-3 · Cited by 36

Pilot study with pegylated liposomal doxorubicin for advanced or unresectable hepatocellular carcinoma

Schmidinger, M., Wenzel, C.-K., Locker, G. J., Muehlbacher, F., Steininger, R., Gnant, M., Crevenna, R., & Budinsky, A. C. (2001) · British Journal of Cancer · doi:10.1054/bjoc.2001.2149 · Cited by 35

Intracytoplasmic gene delivery for in vitro transfection with cytoskeleton-specific immunoliposomes

Khaw, B., DaSilva, J. N., Vural, İ., Narula, J., & Torchilin, V. P. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00364-9 · Cited by 34

Magnetic Resonance Lymphography of Profundus Lymph Nodes with Liposomal Gadolinium-Diethylenetriamine Pentaacetic Acid.

Fujimoto, Y., Okuhata, Y., TYNGI, S., Namba, Y., & Oku, N. (2000) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.23.97 · Cited by 34

ATP-Containing Immunoliposomes Specific for Cardiac Myosin

Liang, W., Levchenko, T. S., Khaw, B., & Torchilin, V. P. (2004) · Current Drug Delivery · doi:10.2174/1567201043480063 · Cited by 34

Treatment with Liposome-Bound Recombinant Human Tumor Necrosis Factor-α Suppresses Parasitemia and Protects against Plasmodium berghei k173-Induced Experimental Cerebral Malaria in Mice

Postma, N. S., Crommelin, D. J. A., Eling, W. M. C., & Zuidema, J. (1999) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37932-7 · Cited by 34

Liposome transduction into cells enhanced by haptotactic peptides (Haptides) homologous to fibrinogen C-termini

Gorodetsky, R., Levdansky, L., Vexler, A. M., Shimeliovich, I., Kassis, I., Ben‐Moshe, M., Magdassi, S., & Marx, G. S. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2003.12.023 · Cited by 33

Treatment with liposome-bound recombinant human tumor necrosis factor-alpha suppresses parasitemia and protects against Plasmodium berghei k173-induced experimental cerebral malaria in mice.

Postma, N. S., Crommelin, D. J. A., Eling, W. M. C., et al. (1999) · PubMed · Cited by 32

Cytosolic delivery of macromolecules

Asokan, A., & Cho, M. J. (2003) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(03)00050-6 · Cited by 31

Immunoliposomal fenretinide: a novel antitumoral drug for human neuroblastoma

Raffaghello, L., Pagnan, G., Pastorino, F., Cosimo, E., Brignole, C., Marimpietri, D., Bogenmann, E., Ponzoni, M., & Montaldo, P. G. (2003) · Cancer Letters · doi:10.1016/s0304-3835(03)00097-1 · Cited by 31

In vivo photosensitizing efficiency of a diphenylchlorin sensitizer: interest of a DMPC liposome formulation

Bourré, L. (2003) · Pharmacological Research · doi:10.1016/s1043-6618(02)00312-2 · Cited by 31

Adenosine Triphosphate Liposomes: Encapsulation and Distribution Studies

Guo-Xing, X., Xing-hui, X., Fang-Yu, L., De-Liang, Z., Dao‐Sheng, Z., Ding-Jiu, H., & Ming-Xin, H. (1990) · Pharmaceutical Research · doi:10.1023/a:1015837321087 · Cited by 30

Virosome influenza vaccine in children

Herzog, C., Metcalfe, I. C., & Schaad, U. B. (2002) · Vaccine · doi:10.1016/s0264-410x(02)00508-x · Cited by 30

Phase I study of pegylated liposomal doxorubicin (Caelyx) in combination with carboplatin in patients with advanced solid tumors.

Gonçalvès, A., Braud, A. C., Viret, F., Genre, D., Gravis, G., Tarpin, C., Giovannini, M. F., Maraninchi, D., & Viens, P. (2003) · PubMed · Cited by 30

Liposomal atp or NAD+ protects human endothelial cells from energy failure in a cell culture model of sepsis.

Han, Y. Y., Huang, L., Jackson, E. K., Dubey, R. K., Gillepsie, D. G., & Carcillo, J. A. (2001) · PubMed · Cited by 28

Liposomal ATP Protects the Liver from Injury during Shock

Konno, H., Matin, A. F., Maruo, Y., Nakamura, S., & Baba, S. (2008) · European Surgical Research · doi:10.1159/000129451 · Cited by 28

Hepatic Preservation, Liposomally Entrapped Adenosine Triphosphate and Nitric Oxide Production: a Study of Energy State and Protein Metabolism in the Cold-Stored Rat Liver

Neveux, N., Bandt, J. P. D., Chaumeil, J. C., & Cynober, L. (2002) · Scandinavian Journal of Gastroenterology · doi:10.1080/003655202320378266 · Cited by 27

A novel and simple type of liposome carrier for recombinant interleukin-2

Kanaoka, E., Takahashi, K., Yoshikawa, T., Jizomoto, H., Nishihara, Y., & Hirano, K. (2001) · Journal of Pharmacy and Pharmacology · doi:10.1211/0022357011775523 · Cited by 26

Phagocytosis in vitro of polyethylene glycol-modified liposome-encapsulated hemoglobin by human peripheral blood monocytes plus macrophages through scavenger receptors

Shibuya-Fujiwara, N., Hirayama, F., Ogata, Y., Ikeda, H., & Ikebuchi, K. (2001) · Life Sciences · doi:10.1016/s0024-3205(01)01392-3 · Cited by 25

Surface Modification of Liposomes

Torchiiin, V. P., Weissig, V., Martin, F. J., Heath, T. D., & New, R. R. C. (2003) · Oxford University Press eBooks · doi:10.1093/oso/9780199636556.003.0007 · Cited by 23

Liposomally entrapped adenosine triphosphate

Laham, A., Claperon, N., Durussel, J. J., Fattal, E., Delattre, J., Puisieux, F., Couvreur, P., & Rossignol, P. (1988) · Journal of Chromatography A · doi:10.1016/s0021-9673(00)94549-7 · Cited by 22

Rapid Antibody Response after Vaccination with a Virosomal Hepatitis A Vaccine

Ambrosch, F., Finkel, B., Herzog, C., Koren, A., & Kollaritsch, H. (2004) · Infection · doi:10.1007/s15010-004-3147-4 · Cited by 21

Bioenergetic effect of liposomal coenzyme Q10 on myocardial ischemia reperfusion injury

Niibori, K., Wroblewski, K. P., Yokoyama, H., Crestanello, J. A., & Whitman, G. J. R. (1999) · BioFactors · doi:10.1002/biof.5520090228 · Cited by 21

Oral Delivery of Antigens in Liposomes with Some Lipid Compositions Modulates Oral Tolerance to the Antigens

Masuda, K., Horie, K., Suzuki, R., Yoshikawa, T., & Hirano, K. (2002) · Microbiology and Immunology · doi:10.1111/j.1348-0421.2002.tb02677.x · Cited by 20

Experimental photodynamic therapy with MESO‐tetrakisphenylporphyrin (TPP) in liposomes leads to disintegration of human amelanotic melanoma implanted to nude mice

Ježek, P., Nekvasil, M., Škobisová, E., Urbánková, E., Jirsa, M., Zadinová, M., POUCKOVA, P., & Klepáček, I. (2002) · International Journal of Cancer · doi:10.1002/ijc.10857 · Cited by 20

Nanocarriers as an emerging platform for cancer therapy

Peer, D., Karp, J. M., Hong, S., Farokhzad, O. C., Margalit, R., & Langer, R. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.387 · Cited by 8,710

Principles of nanoparticle design for overcoming biological barriers to drug delivery

Blanco, E., Shen, H., & Ferrari, M. (2015) · Nature Biotechnology · doi:10.1038/nbt.3330 · Cited by 7,002

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

Suk, J. S., Xu, Q., Kim, N., Hanes, J., & Ensign, L. M. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.09.012 · Cited by 4,523

Strategies in the design of nanoparticles for therapeutic applications

Petros, R. A., & DeSimone, J. M. (2010) · Nature Reviews Drug Discovery · doi:10.1038/nrd2591 · Cited by 3,651

The golden age: gold nanoparticles for biomedicine

Dreaden, E. C., Alkilany, A. M., Huang, X., Murphy, C. J., & El‐Sayed, M. A. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15237h · Cited by 3,659

Liposomes in Drug Delivery

Torchilin, V. P. (2011) · Springer eBooks · doi:10.1007/978-1-4614-0881-9_11 · Cited by 31

Liposomes as Drug Carriers: Recent Trends and Progress

Uster, P. S. (1989) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600780819 · Cited by 73

Development of liposomes as pharmaceutical carriers for antibiotic and gene delivery

Bashi, D., & Yahya, Y. H. (2017)

Current Trends in Liposome Research

ElBayoumi, T. A., & Torchilin, V. P. (2009) · Methods in molecular biology · doi:10.1007/978-1-60327-360-2_1 · Cited by 136

Liposomes as a drug delivery system

Wang, D. (1999) · Shengming kexue · Cited by 6