Cited by 5,282Nanoparticle-Based Drug DeliveryAdvanced Drug Delivery SystemsRNA Interference and Gene Delivery

The DOI matches its Crossref record; 209 of the 210 references it cites were found in a registry or an index.

Recent advances with liposomes as pharmaceutical carriers

Torchilin, Vladimir P.·2005·Nature Reviews Drug Discovery

Open this paper in CoChat — free account

Abstract

Liposomes - microscopic phospholipid bubbles with a bilayered membrane structure - have received a lot of attention during the past 30 years as pharmaceutical carriers of great potential. More recently, many new developments have been seen in the area of liposomal drugs - from clinically approved products to new experimental applications, with gene delivery and cancer therapy still being the principal areas of interest. For further successful development of this field, promising trends must be identified and exploited, albeit with a clear understanding of the limitations of these approaches.

Integrity signals

Registry

Crossref · 10.1038/nrd1632

Cites

209 of 209 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cellular uptake of the tat protein from human immunodeficiency virus
Frankel, A. D., & Pabo, C. O. (1988) · Cell · doi:10.1016/0092-8674(88)90263-2 · Cited by 2,782
Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes
Klibanov, A. L., Maruyama, K., Torchilin, V. P., & Huang, L. (1990) · FEBS Letters · doi:10.1016/0014-5793(90)81016-h · Cited by 2,030
Self-citation
Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
Wadia, J. S., Stan, R. V., & Dowdy, S. F. (2004) · Nature Medicine · doi:10.1038/nm996 · Cited by 1,647
Liposomes: From Physics to Applications
Lasiç, D. D. (1993) · Cited by 1,304
Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties
Moghimi, S. M., & Szebeni, J. (2003) · Progress in Lipid Research · doi:10.1016/s0163-7827(03)00033-x · Cited by 1,228
Cationic liposome-mediated transfection
Felgner, P. L., & RINGOLD, G. M. (1989) · Nature · doi:10.1038/337387a0 · Cited by 989
Folate-mediated delivery of macromolecular anticancer therapeutic agents
Lu, Y. J., & Low, P. S. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00042-x · Cited by 942
Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS
Maeda, H., Sawa, T., & Konno, T. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00309-1 · Cited by 926
TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors
Torchilin, V. P., Rammohan, R., Weissig, V., & Levchenko, T. S. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.151247498 · Cited by 777
Self-citation
Lipid vesicles and other colloids as drug carriers on the skin
Cevc, G. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.10.028 · Cited by 703

Flagged first, then by citations

Show all 210 references

1 of the 210 references couldn’t be matched to a known paper.

Research works printed but not linked: 11

Stealth® Liposomes, Chapter 19 (eds Martin, F. & Lasic, D.) 225–237 (CRC Press, Boca Raton, 1995).
Torchilin, V. P. & Klibanov, A. L. in Phospholipid Handbook (ed. Cevc, G.) 293–321 (Marcel Dekker, New York, 1993).
Tu, R., Mohanty, K. & Tirrell, M. Liposomal targeting through peptide-amphiphile functionalization. Pharm. Rev. 7, 36–41 (2004)
Li, H., Song, J. H., Park, J. S. & Han, K. Polyethylene glycol-coated liposomes for oral delivery of recombinant human epidermal growth factor. Int. J. Pharm. 258, 11–19 (2003). · DOI
Lo, Y. L., Tsai, J. C. & Kuo, J. H. Liposomes and disaccharides as carriers in spray-dried powder formulations of superoxide dismutase. J. Control. Release 94, 259–272 (2004). · DOI
Chikh, G. & Schutze-Redelmeier, M. P. Liposomal delivery of CTL epitopes to dendritic cells. Biosci. Rep. 22, 339–353 (2002). · DOI
Chikh, G. G., Kong, S., Bally, M. B., Meunier, J. C. & Schutze-Redelmeier, M. P. Efficient delivery of Antennapedia homeodomain fused to CTL epitope with liposomes into dendritic cells results in the activation of CD8+ T cells. J. Immunol. 167, 6462–6470 (2001). · DOI
Copland, M. J. et al. Liposomal delivery of antigen to human dendritic cells. Vaccine 21, 883–890 (2003). · DOI
Tilcock, C. in Liposomes as Tools in Basic Research and Industry (eds Philippot, J. R. & Schuber, F.) 225–240 (CRC, Boca Raton, 1995).
Gregoriadis, G. (ed.). Liposome Technology vol. 1–3 (CRC, Boca Raton, 1984).
Martin, F. & Lasic, D. (eds.). Stealth Liposomes (CRC, Boca Raton, 1995).

Sorted by citations

Nanocarriers as an emerging platform for cancer therapy
Peer, D., Karp, J. M., Hong, S., Farokhzad, O. C., Margalit, R., & Langer, R. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.387 · Cited by 8,710
Principles of nanoparticle design for overcoming biological barriers to drug delivery
Blanco, E., Shen, H., & Ferrari, M. (2015) · Nature Biotechnology · doi:10.1038/nbt.3330 · Cited by 7,002
PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
Suk, J. S., Xu, Q., Kim, N., Hanes, J., & Ensign, L. M. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.09.012 · Cited by 4,523
Strategies in the design of nanoparticles for therapeutic applications
Petros, R. A., & DeSimone, J. M. (2010) · Nature Reviews Drug Discovery · doi:10.1038/nrd2591 · Cited by 3,651
The golden age: gold nanoparticles for biomedicine
Dreaden, E. C., Alkilany, A. M., Huang, X., Murphy, C. J., & El‐Sayed, M. A. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15237h · Cited by 3,659
Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives
Knop, K., Hoogenboom, R., Fischer, D., & Schubert, U. S. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.200902672 · Cited by 3,533
Knocking down barriers: advances in siRNA delivery
Whitehead, K. A., Langer, R., & Anderson, D. G. (2009) · Nature Reviews Drug Discovery · doi:10.1038/nrd2742 · Cited by 3,115
Nanoparticles in Photodynamic Therapy
Lucky, S. S., Soo, K. C., & Zhang, Y. (2015) · Chemical Reviews · doi:10.1021/cr5004198 · Cited by 2,999
Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
Bertrand, N., Wu, J., Xu, X., Kamaly, N., & Farokhzad, O. C. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.11.009 · Cited by 2,925
Nanoparticles in Medicine: Therapeutic Applications and Developments
Zhang, L., Gu, F., Chan, J. M., Wang, A. Z., Langer, R., & Farokhzad, O. C. (2007) · Clinical Pharmacology & Therapeutics · doi:10.1038/sj.clpt.6100400 · Cited by 2,685
Magnetic nanoparticles in MR imaging and drug delivery
Sun, C., Lee, J. S. H., & Zhang, M. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2008.03.018 · Cited by 2,642
Mesoporous Materials for Drug Delivery
Vallet‐Regí, M., Balas, F., & Arcos, D. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200604488 · Cited by 2,519
Functional Nanomaterials for Phototherapies of Cancer
Cheng, L., Wang, C., Feng, L., Yang, K., & Liu, Z. (2014) · Chemical Reviews · doi:10.1021/cr400532z · Cited by 2,438
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
Cabral, H., Matsumoto, Y., Mizuno, K., Chen, Q., Murakami, M., Kimura, M., Terada, Y., Kano, M. R., Miyazono, K., Uesaka, M., et al. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2011.166 · Cited by 2,429
Liposomes as nanomedical devices
Bozzuto, G., & Molinari, A. (2015) · International Journal of Nanomedicine · doi:10.2147/ijn.s68861 · Cited by 2,382
Lipid NanoparticlesFrom Liposomes to mRNA Vaccine Delivery, a Landscape of Research Diversity and Advancement
Tenchov, R., Bird, R., Curtze, A. E., & Zhou, Q. (2021) · ACS Nano · doi:10.1021/acsnano.1c04996 · Cited by 2,221
A review of stimuli-responsive nanocarriers for drug and gene delivery
Ganta, S., Devalapally, H., Shahiwala, A., & Amiji, M. M. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2007.12.017 · Cited by 2,198
Magnetic Nanoparticles: Design and Characterization, Toxicity and Biocompatibility, Pharmaceutical and Biomedical Applications
Reddy, L. H., Arias, J. L., Nicolas, J., & Couvreur, P. (2012) · Chemical Reviews · doi:10.1021/cr300068p · Cited by 2,010
Polymer conjugates as anticancer nanomedicines
Duncan, R. (2006) · Nature reviews. Cancer · doi:10.1038/nrc1958 · Cited by 1,956
Biodegradable luminescent porous silicon nanoparticles for in vivo applications
Park, J., Gu, L., von Maltzahn, G., Ruoslahti, E. I., Bhatia, S. N., & Sailor, M. J. (2009) · Nature Materials · doi:10.1038/nmat2398 · Cited by 1,917
Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy
Pérez‐Herrero, E., & Fernández‐Medarde, A. (2015) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2015.03.018 · Cited by 1,936
“Nanoantibiotics”: A new paradigm for treating infectious diseases using nanomaterials in the antibiotics resistant era
Huh, A. J., & Kwon, Y. J. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.07.002 · Cited by 1,920
Targeted Drug Delivery with Polymers and Magnetic Nanoparticles: Covalent and Noncovalent Approaches, Release Control, and Clinical Studies
Ulbrich, K., Holá, K., Šubr, V., Bakandritsos, A., Tuček, J., & Zbořil, R. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00589 · Cited by 1,759
Nanoparticle-Based Drug Delivery in Cancer Therapy and Its Role in Overcoming Drug Resistance
Yao, Y., Zhou, Y., Liu, L., Xu, Y., Chen, Q., Wang, Y., Wu, S., Deng, Y., Zhang, J., & Shao, A. (2020) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.00193 · Cited by 1,451
New developments in liposomal drug delivery
Pattni, B. S., Chupin, V. V., & Torchilin, V. P. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00046 · Cited by 1,600
Self-citation
Effective use of nanocarriers as drug delivery systems for the treatment of selected tumors
Din, F. U., Aman, W., Ullah, I., Qureshi, O. S., Mustapha, O., Shafique, S., & Zeb, A. (2017) · International Journal of Nanomedicine · doi:10.2147/ijn.s146315 · Cited by 1,625
Nanoparticle Delivery of Cancer Drugs
Wang, A. Z., Langer, R., & Farokhzad, O. C. (2011) · Annual Review of Medicine · doi:10.1146/annurev-med-040210-162544 · Cited by 1,575
Liposomes: Structure, composition, types, and clinical applications
Nsairat, H., Khater, D., Sayed, U., Odeh, F., Al Bawab, A., & Alshaer, W. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e09394 · Cited by 1,561
Functionalizing Nanoparticles with Biological Molecules: Developing Chemistries that Facilitate Nanotechnology
Sapsford, K. E., Algar, W. R., Berti, L., Gemmill, K. B., Casey, B. J., Oh, E., Stewart, M. H., & Medintz, I. L. (2013) · Chemical Reviews · doi:10.1021/cr300143v · Cited by 1,470
Functionalized mesoporous silica materials for controlled drug delivery
Yang, P., Gai, S., & Lin, J. (2012) · Chemical Society Reviews · doi:10.1039/c2cs15308d · Cited by 1,423
Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination
Zhang, Y.-N., Poon, W., Tavares, A. J., McGilvray, I. D., & Chan, W. C. W. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.01.020 · Cited by 1,388
Nanomedicine—Challenge and Perspectives
Riehemann, K., Schneider, S. W., Luger, T. A., Godin, B., Mauro Ferrari, B., & Fuchs, H. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200802585 · Cited by 1,310
Imaging and drug delivery using theranostic nanoparticles
Janib, S. M., Moses, A. S., & MacKay, J. A. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.08.004 · Cited by 1,278
Nanomaterials for Theranostics: Recent Advances and Future Challenges
Lim, E., Kim, T., Paik, S., Haam, S., Huh, Y., & Lee, K. (2014) · Chemical Reviews · doi:10.1021/cr300213b · Cited by 1,248
Design of liposomes as drug delivery system for therapeutic applications
Guimarães, D., Cavaco-Paulo, A. M., & Nogueira, E. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.120571 · Cited by 1,266
Multifunctional Uniform Nanoparticles Composed of a Magnetite Nanocrystal Core and a Mesoporous Silica Shell for Magnetic Resonance and Fluorescence Imaging and for Drug Delivery
Kim, J., Kim, H. S., Lee, N., Kim, T., Kim, H., Yu, T., Song, I. C., Moon, W. K., & Hyeon, T. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200802469 · Cited by 1,241
Nanomaterials for cancer therapy: current progress and perspectives
Cheng, Z., Li, M., Dey, R., & Chen, Y. (2021) · Journal of Hematology & Oncology · doi:10.1186/s13045-021-01096-0 · Cited by 1,214
Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions
Parodi, A., Quattrocchi, N., van de Ven, A. L., Chiappini, C., Evangelopoulos, M., Martinez, J. O., Brown, B. S., Khaled, S. Z., Yazdi, I. K., Enzo, M. V., et al. (2012) · Nature Nanotechnology · doi:10.1038/nnano.2012.212 · Cited by 1,174
Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect
Maeda, H., Bharate, G. Y., & Daruwalla, J. (2008) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2008.11.010 · Cited by 1,171
Hydrogels for Protein Delivery
Vermonden, T., Censi, R., & Hennink, W. E. (2012) · Chemical Reviews · doi:10.1021/cr200157d · Cited by 1,111
Lipid-Based Nanoparticles as Pharmaceutical Drug Carriers: From Concepts to Clinic
Puri, A., Loomis, K. H., Smith, B. J., Lee, J. H., Yavlovich, A., Heldman, E., & Blumenthal, R. P. (2009) · Critical Reviews in Therapeutic Drug Carrier Systems · doi:10.1615/critrevtherdrugcarriersyst.v26.i6.10 · Cited by 1,099
Functionalized Carbon Nanotubes in Drug Design and Discovery
Prato, M., Kostarelos, K., & Bianco, A. (2007) · Accounts of Chemical Research · doi:10.1021/ar700089b · Cited by 1,059
Self-Assembled Lipid−Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform
Zhang, L., Chan, J. M., Gu, F., Rhee, J., Wang, A. Z., Radovic‐Moreno, A. F., Alexis, F., Langer, R., & Farokhzad, O. C. (2008) · ACS Nano · doi:10.1021/nn800275r · Cited by 1,042
The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers
Ashley, C. E., Carnes, E. C., Phillips, G. K., Padilla, D., Durfee, P. N., Brown, P. A., Hanna, T. N., Liu, J., Phillips, B., Carter, M. B., et al. (2011) · Nature Materials · doi:10.1038/nmat2992 · Cited by 1,031
Nanomedicine Applications of Hybrid Nanomaterials Built from Metal–Ligand Coordination Bonds: Nanoscale Metal–Organic Frameworks and Nanoscale Coordination Polymers
He, C., Liu, D., & Lin, W. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00125 · Cited by 1,011
Mesoporous Silica Nanoparticles for Intracellular Controlled Drug Delivery
Vivero-Escoto, J. L., Slowing, I. I., Trewyn, B. G., & Lin, V. S. ‐. (2010) · Small · doi:10.1002/smll.200901789 · Cited by 1,024
Physical and chemical stability of drug nanoparticles
Wu, L., Zhang, J., & Watanabe, W. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.02.001 · Cited by 998
Nanomedicine(s) under the Microscope
Duncan, R., & Gaspar, R. S. (2011) · Molecular Pharmaceutics · doi:10.1021/mp200394t · Cited by 1,009
Sol–gel based materials for biomedical applications
Owens, G. J., Singh, R. K., Foroutan, F., Al-Qaysi, M., Han, C., Mahapatra, C., Kim, H., & Knowles, J. C. (2016) · Progress in Materials Science · doi:10.1016/j.pmatsci.2015.12.001 · Cited by 987
Nanotechnology: Intelligent Design to Treat Complex Disease
Couvreur, P., & Vauthier, C. (2006) · Pharmaceutical Research · doi:10.1007/s11095-006-0284-8 · Cited by 992
Targeting nanoparticles to cancer
Wang, M., & Thanou, M. (2010) · Pharmacological Research · doi:10.1016/j.phrs.2010.03.005 · Cited by 949
Biological Photothermal Nanodots Based on Self-Assembly of Peptide–Porphyrin Conjugates for Antitumor Therapy
Zou, Q., Abbas, M., Zhao, L., Li, S., Shen, G., & Yan, X. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.6b11382 · Cited by 929
Functional block copolymer assemblies responsive to tumor and intracellular microenvironments for site-specific drug delivery and enhanced imaging performance
Ge, Z., & Liu, S. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60048c · Cited by 924
Tumor Vascular Permeability, Accumulation, and Penetration of Macromolecular Drug Carriers
Dreher, M. R., Liu, W., Michelich, C. R., Dewhirst, M. W., Yuan, F., & Chilkoti, A. (2006) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djj070 · Cited by 911
Nanomaterials: Applications in Cancer Imaging and Therapy
Barreto, J. A., O’Malley, W., Kubeil, M., Graham, B., Stephan, H., & Spiccia, L. (2011) · Advanced Materials · doi:10.1002/adma.201100140 · Cited by 927
Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective
Ratnam, D. V., Ankola, D. D., Bhardwaj, V., Sahana, D. K., & Kumar, M. N. V. R. (2006) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.04.015 · Cited by 885
Twenty years of cell‐penetrating peptides: from molecular mechanisms to therapeutics
Heitz, F., Morris, M. C., & Divita, G. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00057.x · Cited by 897
Advances in Biomaterials for Drug Delivery
Fenton, O. S., Olafson, K. N., Pillai, P. S., Mitchell, M. J., & Langer, R. (2018) · Advanced Materials · doi:10.1002/adma.201705328 · Cited by 890
Drug delivery systems and materials for wound healing applications
Saghazadeh, S., Rinoldi, C., Schot, M., Kashaf, S. S., Sharifi, F., Jalilian, E., Nuutila, K., Giatsidis, G., Mostafalu, P., Derakhshandeh, H., et al. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.04.008 · Cited by 888
The delivery of therapeutic oligonucleotides
Juliano, R. L. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw236 · Cited by 882
Direct Fabrication and Harvesting of Monodisperse, Shape-Specific Nanobiomaterials
Rolland, J. P., Maynor, B. W., Euliss, L. E., Exner, A. E., Rothrock, G. D., & DeSimone, J. M. (2005) · Journal of the American Chemical Society · doi:10.1021/ja051977c · Cited by 849
Curcumin nanoformulations: A review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment
Naksuriya, O., Okonogi, S., Schiffelers, R. M., & Hennink, W. E. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2013.12.090 · Cited by 856
Size-Dependent Localization and Penetration of Ultrasmall Gold Nanoparticles in Cancer Cells, Multicellular Spheroids, and Tumors in Vivo
Huang, K., Ma, H., Liu, J., Huo, S., Kumar, A., Wei, T., Zhang, X., Jin, S., Gan, Y., Wang, P. C., et al. (2012) · ACS Nano · doi:10.1021/nn301282m · Cited by 859
Chemical Design and Synthesis of Functionalized Probes for Imaging and Treating Tumor Hypoxia
Liu, J., Bu, W., & Shi, J. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00525 · Cited by 842
Multifunctional nanoparticles – properties and prospects for their use in human medicine
Sanvicens, N., & Marco, M. ‐. (2008) · Trends in biotechnology · doi:10.1016/j.tibtech.2008.04.005 · Cited by 857
Mesenchymal stem cell: An efficient mass producer of exosomes for drug delivery
Yeo, R. W. Y., Lai, R. C., Zhang, B., Tan, S. S., Yin, Y., Teh, B. J., & Lim, S. K. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.07.001 · Cited by 746
Tools for translation: non-viral materials for therapeutic mRNA delivery
Hajj, K. A., & Whitehead, K. A. (2017) · Nature Reviews Materials · doi:10.1038/natrevmats.2017.56 · Cited by 799
Emerging Nanotechnology and Advanced Materials for Cancer Radiation Therapy
Song, G., Cheng, L., Chao, Y., Yang, K., & Liu, Z. (2017) · Advanced Materials · doi:10.1002/adma.201700996 · Cited by 781
Giant Vesicles: Preparations and Applications
Walde, P., Cosentino, K., Engel, H., & Stano, P. (2010) · ChemBioChem · doi:10.1002/cbic.201000010 · Cited by 793
Targeted pharmaceutical nanocarriers for cancer therapy and imaging
Torchilin, V. P. (2007) · The AAPS Journal · doi:10.1208/aapsj0902015 · Cited by 771
Self-citation
Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come
Yingchoncharoen, P., Kalinowski, D. S., & Richardson, D. R. (2016) · Pharmacological Reviews · doi:10.1124/pr.115.012070 · Cited by 748
Enzymatic reactions in confined environments
Küchler, A., Yoshimoto, M., Luginbühl, S., Mavelli, F., & Walde, P. (2016) · Nature Nanotechnology · doi:10.1038/nnano.2016.54 · Cited by 739
Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors
Diop-Frimpong, B., Chauhan, V. P., Krane, S., Boucher, Y., & Jain, R. K. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1018892108 · Cited by 733
The journey of a drug-carrier in the body: An anatomo-physiological perspective
Bertrand, N., & Leroux, J. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.09.098 · Cited by 737
Lipid–polymer hybrid nanoparticles as a new generation therapeutic delivery platform: A review
Hadinoto, K., Sundaresan, A., & Cheow, W. S. (2013) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2013.07.002 · Cited by 726
Overcoming the Blood–Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases
Furtado, D., Björnmalm, M., Ayton, S., Bush, A. I., Kempe, K., & Caruso, F. (2018) · Advanced Materials · doi:10.1002/adma.201801362 · Cited by 708
PLGA–lecithin–PEG core–shell nanoparticles for controlled drug delivery
Chan, J. M., Zhang, L., Yuet, K. P., Liao, G., Rhee, J., Langer, R., & Farokhzad, O. C. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.12.013 · Cited by 705
ATP-triggered anticancer drug delivery
Mo, R., Jiang, T., DiSanto, R., Tai, W., & Gu, Z. (2014) · Nature Communications · doi:10.1038/ncomms4364 · Cited by 693
Enzyme-responsive nanomaterials for controlled drug delivery
Hu, Q., Katti, P. S., & Gu, Z. (2014) · Nanoscale · doi:10.1039/c4nr04249b · Cited by 683
Supramolecular chemotherapy based on host–guest molecular recognition: a novel strategy in the battle against cancer with a bright future
Zhou, J., Yu, G., & Huang, F. (2017) · Chemical Society Reviews · doi:10.1039/c6cs00898d · Cited by 681
Cell-penetrating peptides: breaking through to the other side
Koren, E., & Torchilin, V. P. (2012) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2012.04.012 · Cited by 694
Self-citation
Adapting liposomes for oral drug delivery
He, H., Lu, Y., Qi, J., Zhu, Q., Chen, Z., & Wu, W. (2019) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2018.06.005 · Cited by 663
Current Trends in The Use of Liposomes for Tumor Targeting
Deshpande, P. P., Biswas, S., & Torchilin, V. P. (2013) · Nanomedicine · doi:10.2217/nnm.13.118 · Cited by 663
Self-citation
Size Matters: Gold Nanoparticles in Targeted Cancer Drug Delivery
Dreaden, E. C., Austin, L. A., Mackey, M. A., & El‐Sayed, M. A. (2012) · Therapeutic Delivery · doi:10.4155/tde.12.21 · Cited by 656
Combination therapy: Opportunities and challenges for polymer–drug conjugates as anticancer nanomedicines
Greco, F., & Vicent, M. J. (2009) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.05.006 · Cited by 654
A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas
Lee, C., Gillies, E. R., Fox, M. E., Guillaudeu, S. J., Fréchet, J. M. J., Dy, E. E., & Szoka, F. C. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607705103 · Cited by 648
Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles
Singh, A. P., Biswas, A., Shukla, A., & Maiti, P. (2019) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-019-0068-3 · Cited by 645
Methods for characterization of nanoparticles
Kumar, A., & Dixit, C. K. (2017) · Elsevier eBooks · doi:10.1016/b978-0-08-100557-6.00003-1 · Cited by 643
Controlled drug release from pharmaceutical nanocarriers
Lee, J. H., & Yeo, Y. (2014) · Chemical Engineering Science · doi:10.1016/j.ces.2014.08.046 · Cited by 657
Cancer‐Cell‐Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors
Sun, H., Su, J., Meng, Q., Yin, Q., Chen, L., Gu, W., Zhang, P., Zhang, Z., Yu, H., Wang, S., et al. (2016) · Advanced Materials · doi:10.1002/adma.201602173 · Cited by 637
Inorganic nanoparticles for cancer imaging and therapy
Huang, H., Barua, S., Sharma, G., Dey, S. K., & Rege, K. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.06.004 · Cited by 642
Prospects and challenges of extracellular vesicle-based drug delivery system: considering cell source
Meng, W., He, C., Hao, Y., Wang, L., Li, L., & Zhu, G. (2020) · Drug Delivery · doi:10.1080/10717544.2020.1748758 · Cited by 592
Emerging Research and Clinical Development Trends of Liposome and Lipid Nanoparticle Drug Delivery Systems
Kraft, J. C., Freeling, J. P., Wang, Z., & Ho, R. J. Y. (2013) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.23773 · Cited by 614
Remotely Triggerable Drug Delivery Systems
Timko, B. P., Dvir, T., & Kohane, D. S. (2010) · Advanced Materials · doi:10.1002/adma.201002072 · Cited by 618
Nanocarriers for cancer-targeted drug delivery
Kumari, P., Ghosh, B., & Biswas, S. (2015) · Journal of drug targeting · doi:10.3109/1061186x.2015.1051049 · Cited by 619
Polymeric nanoparticles: Promising platform for drug delivery
El‐Say, K. M., & El‐Sawy, H. S. (2017) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2017.06.052 · Cited by 611
Nanotheranostics ˗ Application and Further Development of Nanomedicine Strategies for Advanced Theranostics
Muthu, M. S., Leong, D. T., Mei, L., & Feng, S. (2014) · Theranostics · doi:10.7150/thno.8698 · Cited by 609
Nanotechnology in Therapeutics: A Focus on Nanoparticles as A Drug Delivery System
Bamrungsap, S., Zhao, Z., Chen, T., Wang, L., Li, C., Fu, T., & Tan, W. (2012) · Nanomedicine · doi:10.2217/nnm.12.87 · Cited by 624
pH-Triggered Controlled Drug Release from Mesoporous Silica Nanoparticles via Intracelluar Dissolution of ZnO Nanolids
Muhammad, F., Guo, M., Qi, W., Sun, F., Wang, A., Guo, Y., & Zhu, G. (2011) · Journal of the American Chemical Society · doi:10.1021/ja200328s · Cited by 606
Formulation, stabilisation and encapsulation of bacteriophage for phage therapy
Malik, D. J., Sokolov, I. J., Vinner, G. K., Mancuso, F., Cinquerrui, S., Vladisavljevic, G. T., Clokie, M. R. J., Garton, N. J., Stapley, A. G. F., & Kirpichnikova, A. (2017) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2017.05.014 · Cited by 594

Authors: Torchilin, V. P.
Affiliations: Northeastern University (US)
Corresponding author: Torchilin, Vladimir P.
ORCID: Torchilin, Vladimir P.
Venue: Nature Reviews Drug Discovery
Publisher: Springer Science and Business Media LLC
Published: 2005-02
Volume: 4
Issue: 2
Pages: 145-160
ISSN: 1474-1776 (ISSN-L)
1474-1784
DOI: 10.1038/nrd1632
OpenAlex: W2061510929
Cited by: 5,282
References: 210
Citations by year: 2026: 183 · 2025: 227 · 2024: 217 · 2023: 222 · 2022: 284 · 2021: 252 · 2020: 311 · 2019: 275 · 2018: 274 · 2017: 302 · 2016: 343 · 2015: 324 · 2014: 368 · 2013: 334 · 2012: 351
FWCI: 7.98
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature Reviews Drug Discovery (publishedVersion)
PubMed (publishedVersion)
Topics: Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Interference and Gene Delivery
Keywords: liposomes, drug carriers, liposomal drugs, gene delivery, cancer therapy, phospholipid bilayers, drug delivery systems
MeSH terms: Animals, Humans, Liposomes, Technology, Pharmaceutical

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Recent advances with liposomes as pharmaceutical carriers

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks