The DOI matches its Crossref record; 176 of the 176 references it cites were found in a registry or an index.
Targeting of tetraspanin proteins — potential benefits and strategies
Open accessAbstract
The tetraspanin transmembrane proteins have emerged as key players in malignancy, the immune system, during fertilization and infectious disease processes. Tetraspanins engage in a wide range of specific molecular interactions, occurring through the formation of tetraspanin-enriched microdomains (TEMs). TEMs therefore serve as a starting point for understanding how tetraspanins affect cell signalling, adhesion, morphology, motility, fusion and virus infection. An abundance of recent evidence suggests that targeting tetraspanins, for example, by monoclonal antibodies, soluble large-loop proteins or RNAi technology, should be therapeutically beneficial.
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Cites
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RetractedExosome mimetics: a novel class of drug delivery systems
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Metadata
- Authors
- Hemler, M. E.
- Venue
- Nature Reviews Drug Discovery
- Published
- 2008-09
- Volume
- 7
- Issue
- 9
- Pages
- 747-758
- ISSN
- 1474-1776 (ISSN-L)
- 1474-1784
- OpenAlex
- W1967427925
- Cited by
- 345
- References
- 176
- FWCI
- 1.58
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
