HDL-targeted therapies: progress, failures and future

Kingwell, Bronwyn A., Chapman, M. John, Kontush, Anatol, Miller, Norman E.·2014·Nature Reviews Drug Discovery

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    Kelly A. Manthei, Shyh‐Ming Yang, Bolormaa Baljinnyam, Louise C. Chang, Alisa Glukhova, Wenmin Yuan, Lita A. Freeman, David J. Maloney, Anna A. Schwendeman, Alan Thomas Remaley et al. · 2018 · eLife
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  4. Loss of LCAT activity in the golden Syrian hamster elicits pro-atherogenic dyslipidemia and enhanced atherosclerosis
    Dong Zhao, Haozhe Shi, Mingming Zhao, Xin Zhang, Wei Y. Huang, Yuhui Wang, Lemin Zheng, Xunde Xian, Chaojie Liu · 2018 · Metabolism
  5. The pleiotropic vasoprotective functions of high density lipoproteins (HDL)
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  8. Current and Emerging Reconstituted HDL-apoA-I and HDL-apoE Approaches to Treat Atherosclerosis
    Eftaxia-Konstantina Valanti, Katerina Dalakoura-Karagkouni, Despina Sanoudou · 2018 · Journal of Personalized Medicine
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    Evgenia Gourgari, Martin Peter Playford, Umberto Campia, Amit Kumar Dey, Fran R. Cogen, Stephanie Gubb-Weiser, Mihriye Méte, Sameer Y. Desale, Maureen L. Sampson, Allen J. Taylor et al. · 2018 · Cardiovascular Diabetology
  10. TRAK2, a novel regulator of ABCA1 expression, cholesterol efflux and HDL biogenesis
    Nicole J. Lake, Rachael L Taylor, Hugh Trahair, Harikrishnan Kaipananickal, Joanne E. Curran, Marcio Almeida, Hemant R. Kulkarni, Nigora Mukhamedova, Anh Hoang, Hann Low et al. · 2017 · European Heart Journal
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    Dustin Chernick, Rui Zhong, Ling Li · 2020 · Biomolecules
  12. Small, dense high-density lipoprotein 3 particles exhibit defective antioxidative and anti-inflammatory function in familial hypercholesterolemia: Partial correction by low-density lipoprotein apheresis
    Hala Hussein, Samir Saheb, Martine Couturier, Marielle Atassi, Alexina Orsoni, Alain Carrié, Patrice Thérond, Sandrine Chantepie, Paul Robillard, Éric Bruckert et al. · 2015 · Journal of clinical lipidology
  13. Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal–Induced Inflammatory Responses by Reducing Complement Activation
    Nathalie Niyonzima, Eivind Ottersen Samstad, Marie H Aune, Liv Ryan, Siril Skaret Bakke, Anne Mari Rokstad, Samuel D. Wright, Jan Kristian Damås, Tom Eirik Mollnes, Eicke Latz et al. · 2015 · The Journal of Immunology
  14. Lipoprotein hydrophobic core lipids are partially extruded to surface in smaller HDL: “Herniated” HDL, a common feature in diabetes
    Núria Amigó, Roger Mallol, Mercedes Heras, Sergio Martínez‐Hervás, Francisco Blanco‐Vaca, Joan Carles Escolá‐Gil, Núria Plana, Óscar Yanes, L. Masana, Xavier Correig · 2016 · Scientific Reports
  15. CETP Inhibition Improves HDL Function but Leads to Fatty Liver and Insulin Resistance in CETP-Expressing Transgenic Mice on a High-Fat Diet
    Lin Zhu, Thao N. Luu, Christopher H. Emfinger, Bryan A. Parks, Jeanne Shi, Elijah Trefts, Fenghua Zeng, Zsuzsanna Kuklenyik, Raymond Clement Harris, David H. Wasserman et al. · 2018 · Diabetes
  16. Roles of Reconstituted High-Density Lipoprotein Nanoparticles in Cardiovascular Disease: A New Paradigm for Drug Discovery
    Jiansheng Huang, Dongdong Wang, Li‐Hao Huang, Hui Huang · 2020 · International Journal of Molecular Sciences
  17. Molecular dynamics simulations of lipid nanodiscs
    Mohsen Pourmousa, Richard W. Pastor · 2018 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  18. Characterization of apolipoprotein A-I peptide phospholipid interaction and its effect on HDL nanodisc assembly
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  19. Aggregation Susceptibility of Low-Density Lipoproteins—A Novel Modifiable Biomarker of Cardiovascular Risk
    Katariina Öörni, Petri T. Kovanen · 2021 · Journal of Clinical Medicine
  20. A Review of the Anti-Obesity Effects of Wild Edible Plants in the Mediterranean Diet and Their Active Compounds: From Traditional Uses to Action Mechanisms and Therapeutic Targets
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  21. Increased atherosclerosis in P2Y13/apolipoprotein E double-knockout mice: contribution of P2Y13 to reverse cholesterol transport
    Laeticia Lichtenstein, Nizar Serhan, Sara Espinosa Delgado, Aurélie Fabre, Wijtske Annema, Uwe J.F. Tietge, Bernard Robaye, Jean‐Marie Boeynaems, Muriel Laffargue, Bertrand Perret et al. · 2015 · Cardiovascular Research
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    Wan N. Wan Sulaiman, MURIEL J. CASLAKE, Christian Delles, Helén Karlsson, Monique T Mulder, Delyth Graham, Dilys J. Freeman · 2016 · Clinical Science
  23. Phosphatidylserine enhances anti‐inflammatory effects of reconstituted HDL in macrophages via distinct intracellular pathways
    Maryam Darabi, Marie Lhomme, Veronica D. Dahik, Isabelle Guillas, Éric Frisdal, Emilie Tubeuf, Lucie Poupel, Mili Patel, Emmanuel L. Gautier, Thierry Huby et al. · 2022 · The FASEB Journal
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    Le Shu, Montgomery Blencowe, Xia Yang · 2018 · Frontiers in Cardiovascular Medicine
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    Linda Zhang, Annet Kirabo, Jiansheng Huang, MacRae F. Linton, Sean S. Davies, Katherine T. Murray · 2020 · The Annual Review of Pharmacology and Toxicology
  26. Cumulative remnant cholesterol predicts cardiovascular outcomes in elderly patients with atherosclerotic cardiovascular disease
    Zhiwen Xiao, Zhongqiu Lin, Lin Xu, Wenlong Xu, Haoxiang Huang, Yuegang Wang, Shiping Cao, Zhiquan Xie, Wangjun Liao, Yulin Liao et al. · 2023 · European Journal of Preventive Cardiology
  27. Targeted invalidation of SR-B1 in macrophages reduces macrophage apoptosis and accelerates atherosclerosis
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  29. Macrophage apoAI protects against dyslipidemia-induced dermatitis and atherosclerosis without affecting HDL
    Hagai Tavori, Yan Ru Su, Patricia G. Yancey, Ilaria Giunzioni, Ashley J. Wilhelm, John L. Blakemore, Manal Zabalawi, MacRae F. Linton, Mary G. Sorci‐Thomas, Sergio Fazio · 2015 · Journal of Lipid Research
  30. Re-evaluation of cholesteryl ester transfer protein function in atherosclerosis based upon genetics and pharmacological manipulation
    Shizuya Yamashita, Yūji Matsuzawa · 2016 · Current Opinion in Lipidology
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    Roosmarijn F.H. Lemmers, Mandy van Hoek, Aloysius G. Lieverse, Adrie J.M. Verhoeven, Eric J.G. Sijbrands, Monique T Mulder · 2017 · Journal of clinical lipidology
  32. Long‐Term Supplementation of Black Elderberries Promotes Hyperlipidemia, but Reduces Liver Inflammation and Improves HDL Function and Atherosclerotic Plaque Stability in Apolipoprotein E‐Knockout Mice
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  33. Effect of the ABCA1 agonist CS-6253 on amyloid-β and lipoprotein metabolism in cynomolgus monkeys
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  35. HDL-C vs HDL-P: How Changing One Letter Could Make a Difference in Understanding the Role of High-Density Lipoprotein in Disease
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  36. Agonistic Human Antibodies Binding to Lecithin-Cholesterol Acyltransferase Modulate High Density Lipoprotein Metabolism
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  37. Apolipoprotein E-containing high-density lipoprotein (HDL) modifies the impact of cholesterol-overloaded HDL on incident coronary heart disease risk: A community-based cohort study
    Yue Qi, Jing Liu, Wei Wang, Miao Wang, Fan Zhao, Jiayi Sun, Jun Liu, Dong Hui Zhao · 2017 · Journal of clinical lipidology
  38. Potential Contribution of Short Chain Fatty Acids to Hepatic Apolipoprotein A-I Production
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  39. Apolipoprotein A-I Is a Prognosticator of Nasopharyngeal Carcinoma in the Era of Intensity-modulated Radiotherapy
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  40. Antibody Targeted PET Imaging of 64 Cu-DOTA-Anti-CEA PEGylated Lipid Nanodiscs in CEA Positive Tumors
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  41. Oxidative modification of HDL by lipid aldehydes impacts HDL function
    Reza Fadaei, Sean S. Davies · 2022 · Archives of Biochemistry and Biophysics
  42. Treatment with apolipoprotein A1 protects mice against doxorubicin-induced cardiotoxicity in a scavenger receptor class B, type I-dependent manner
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  43. Serum levels of small HDL particles are negatively correlated with death or lung transplantation in an observational study of idiopathic pulmonary fibrosis
    Amisha V. Barochia, Maryann M. Kaler, Nargues A. Weir, Elizabeth M. Gordon, Debbie M Figueroa, Xianglan Yao, Merte Lemma Woldehanna, Maureen L. Sampson, Alan Thomas Remaley, Geraldine M. Grant et al. · 2021 · European Respiratory Journal
  44. Reconstituted HDL as a therapeutic delivery device
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    Eider Pascual Corrales, Javier Gómez‐Ambrosi, Rafael Moncada, Víctor Valentí, Victoria Catalán, Amaia Rodrı́guez, Beatriz Ramírez, Camilo Silva, Marı́a J. Gil, Javier Salvador et al. · 2016 · Obesity Surgery
  46. FACEing reality: productive tensions between our epidemiological questions, methods and mission
    Nancy Krieger, George Davey Smith · 2016 · International Journal of Epidemiology
  47. Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann–Pick diseases
    Mark L. Schultz, Maria V. Fawaz, Ruth D. Azaria, Todd Charles Hollon, Elaine A. Liu, Thaddeus J. Kunkel, Troy A. Halseth, Kelsey L. Krus, Ran Ming, Emily E. Morin et al. · 2019 · BMC Medicine
  48. Dissecting the proteome of lipoproteins: New biomarkers for cardiovascular diseases?
    Anne von Zychlinski, Torsten Kleffmann · 2015 · Translational Proteomics
  49. FR171456 is a specific inhibitor of mammalian NSDHL and yeast Erg26p
    Stephen B. Helliwell, Shantanu Karkare, Marc Bergdoll, Alain Rahier, Juliet R. Leighton-Davis, Céline Fioretto, Thomas Aust, Ireos Filipuzzi, Mathias Ugelstad Frederiksen, John Gounarides et al. · 2015 · Nature Communications
  50. Effect of Synthetic High Density Lipoproteins Modification with Polyethylene Glycol on Pharmacokinetics and Pharmacodynamics
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  51. The Search for Dietary Supplements to Elevate or Activate Circulating Paraoxonases
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  53. A systematic review of the biodistribution of biomimetic high-density lipoproteins in mice
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  54. Exploring the therapeutic potential of the bioinspired reconstituted high density lipoprotein nanostructures
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  55. The A’s Have It
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  57. Effects of Freeze-Dried Grape Powder on High-Density Lipoprotein Function in Adults with Metabolic Syndrome: A Randomized Controlled Pilot Study
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  58. Immune-mediated and lipid-mediated platelet function in atherosclerosis
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  59. CETP inhibitors and cardiovascular disease: Time to think again
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