The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Conserved non-genic sequences — an unexpected feature of mammalian genomes
Open accessAbstract
Mammalian genomes contain highly conserved sequences that are not functionally transcribed. These sequences are single copy and comprise approximately 1–2% of the human genome. Evolutionary analysis strongly supports their functional conservation, although their potentially diverse, functional attributes remain unknown. It is likely that genomic variation in conserved non-genic sequences is associated with phenotypic variability and human disorders. So how might their function and contribution to human disorders be examined?
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Citations
Cites
Initial sequencing and comparative analysis of the mouse genome
Mouse Genome Sequencing Consortium (2002) · Nature · doi:10.1038/nature01262 · Cited by 7,187
Ultraconserved Elements in the Human Genome
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Phylogenetic Shadowing of Primate Sequences to Find Functional Regions of the Human Genome
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Self-citationβ-Globin gene inactivation by DNA translocation in γβ-thalassaemi
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Cited by
The ENCODE Project Consortium (2007) · Nature · doi:10.1038/nature05874 · Cited by 5,223
Forces shaping the fastest evolving regions in the human genome
Pollard, K. S., Salama, S. R., King, B., Kern, A. D., Dreszer, T., Katzman, S., Siepel, A., Pedersen, J. S., Bejerano, G., Baertsch, R., et al. (2006) · PLoS Genetics · doi:10.1371/journal.pgen.0020168 · Cited by 511
Variation in the mutation rate across mammalian genomes
Hodgkinson, A., & Eyre-Walker, A. (2011) · Nature Reviews Genetics · doi:10.1038/nrg3098 · Cited by 487
How can we realize the promise of personalized antidepressant medicines?
Holsboer, F. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2453 · Cited by 177
Chang, S., & Aune, T. M. (2007) · Nature Immunology · doi:10.1038/ni1473 · Cited by 149
A family of conserved noncoding elements derived from an ancient transposable element
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CEGA—a catalog of conserved elements from genomic alignments
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Metadata
- Authors
- Dermitzakis, E. T., Reymond, A., & Antonarakis, S. E.
- Venue
- Nature Reviews Genetics
- Published
- 2005-02
- Volume
- 6
- Issue
- 2
- Pages
- 151-157
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W1600524753
- Cited by
- 265
- References
- 8
- FWCI
- 4.02
- Type
- journal article
- Language
- en
- Open access
- green
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