The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Conserved non-genic sequences — an unexpected feature of mammalian genomes
Open accessAbstract
Mammalian genomes contain highly conserved sequences that are not functionally transcribed. These sequences are single copy and comprise approximately 1–2% of the human genome. Evolutionary analysis strongly supports their functional conservation, although their potentially diverse, functional attributes remain unknown. It is likely that genomic variation in conserved non-genic sequences is associated with phenotypic variability and human disorders. So how might their function and contribution to human disorders be examined?
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Cites
Initial sequencing and comparative analysis of the mouse genome
Mouse Genome Sequencing Consortium (2002) · Nature · doi:10.1038/nature01262 · Cited by 7,187
Ultraconserved Elements in the Human Genome
Bejerano, G., Pheasant, M., Makunin, I., Stephen, S., Kent, W. J., Mattick, J. S., & Haussler, D. (2004) · Science · doi:10.1126/science.1098119 · Cited by 1,732
Lettice, L. A. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg180 · Cited by 1,164
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Phylogenetic Shadowing of Primate Sequences to Find Functional Regions of the Human Genome
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Dermitzakis, E. T., & Clark, A. G. (2002) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a004169 · Cited by 463
Self-citationβ-Globin gene inactivation by DNA translocation in γβ-thalassaemi
Kioussis, D., Vanin, E., deLange, T., Flavell, R. A., & Grosveld, F. G. (1983) · Nature · doi:10.1038/306662a0 · Cited by 264
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Cited by
The ENCODE Project Consortium (2007) · Nature · doi:10.1038/nature05874 · Cited by 5,223
Forces shaping the fastest evolving regions in the human genome
Pollard, K. S., Salama, S. R., King, B., Kern, A. D., Dreszer, T., Katzman, S., Siepel, A., Pedersen, J. S., Bejerano, G., Baertsch, R., et al. (2006) · PLoS Genetics · doi:10.1371/journal.pgen.0020168 · Cited by 511
Variation in the mutation rate across mammalian genomes
Hodgkinson, A., & Eyre-Walker, A. (2011) · Nature Reviews Genetics · doi:10.1038/nrg3098 · Cited by 487
How can we realize the promise of personalized antidepressant medicines?
Holsboer, F. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2453 · Cited by 177
Chang, S., & Aune, T. M. (2007) · Nature Immunology · doi:10.1038/ni1473 · Cited by 149
Metadata
- Authors
- Dermitzakis, E. T., Reymond, A., & Antonarakis, S. E.
- Venue
- Nature Reviews Genetics
- Published
- 2005-02
- Volume
- 6
- Issue
- 2
- Pages
- 151-157
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W1600524753
- Cited by
- 265
- References
- 8
- FWCI
- 4.02
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
