The DOI matches its Crossref record; 144 of the 144 references it cites were found in a registry or an index.
An evolutionary view of human recombination
Abstract
Recombination has essential functions in mammalian meiosis, which impose several constraints on the recombination process. However, recent studies have shown that, in spite of these roles, recombination rates vary tremendously among humans, and show marked differences between humans and closely related species. These findings provide important insights into the determinants of recombination rates and raise new questions about the selective pressures that affect recombination over different genomic scales, with implications for human genetics and evolutionary biology.
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In the citing paper
“because short chromosomes have a higher recombination rate 67”
From Genome analysis of the platypus reveals unique signatures of evolution (2008) · cites this paper as [67]
In the citing paper
“Specifically, selection for a recombination driver allele may be favored when it is tightly linked to two or more genes with alleles under selection (61).”
From Comparative analysis of the domestic cat genome reveals genetic signatures underlying feline biology and domestication (2014) · cites this paper as [61]
Citations
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Felsenstein, J. (1974) · Genetics · doi:10.1093/genetics/78.2.737 · Cited by 1,711
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Hill, W. G., & Robertson, A. (2007) · Genetics Research · doi:10.1017/s001667230800949x · Cited by 1,562
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A Fine-Scale Map of Recombination Rates and Hotspots Across the Human Genome
Myers, S., Bottolo, L., Freeman, C., McVean, G., & Donnelly, P. (2005) · Science · doi:10.1126/science.1117196 · Cited by 1,134
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Cited by
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PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice
Baudat, F., Buard, J., Grey, C., Fledel-Alon, A., Ober, C., Przeworski, M., Coop, G., & de Massy, B. (2010) · Science · doi:10.1126/science.1183439 · Cited by 1,026
Self-citationGreat ape genetic diversity and population history
Prado-Martinez, J., Sudmant, P. H., Kidd, J. M., Li, H., Kelley, J. L., Lorente-Galdós, B., Veeramah, K. R., Woerner, A. E., O’Connor, T. D., Santpere, G., et al. (2013) · Nature · doi:10.1038/nature12228 · Cited by 891
Campbell, M. C., & Tishkoff, S. A. (2008) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.9.081307.164258 · Cited by 879
Sex-specific genetic architecture of human disease
Ober, C., Loisel, D. A., & Gilad, Y. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2415 · Cited by 787
Biased gene conversion and the evolution of mammalian genomic landscapes
Duret, L., & Galtier, N. (2009) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-082908-150001 · Cited by 737
Metadata
- Authors
- Coop, G., & Przeworski, M.
- Affiliations
- University of Chicago (US)
- Corresponding author
- Przeworski, Molly
- Venue
- Nature Reviews Genetics
- Published
- 2006-12-05
- Volume
- 8
- Issue
- 1
- Pages
- 23-34
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W2085231911
- Cited by
- 344
- References
- 143
- Citations by year
- 2026: 5 · 2025: 15 · 2024: 12 · 2023: 12 · 2022: 18 · 2021: 53 · 2020: 10 · 2019: 14 · 2018: 13 · 2017: 25 · 2016: 15 · 2015: 17 · 2014: 12 · 2013: 14 · 2012: 12
- FWCI
- 1.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Reviews Genetics (publishedVersion)
- PubMed (publishedVersion)
- Funders
- University of Chicago
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Chromosomal and Genetic Variations
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
- Keywords
- meiotic recombination, recombination rate variation, mammalian meiosis, recombination hotspots, recombination rate evolution, comparative genomics, human genetics
- MeSH terms
- Animals, Crossing Over, Genetic, Biological Evolution, Female, Humans, Male, Mammals, Meiosis, Models, Genetic, Recombination, Genetic, Selection, Genetic, Sex Characteristics, Species Specificity, Linkage Disequilibrium, Genome, Human
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