Microbial metabolites feed into the gut–brain–gut circuit during host metabolism
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Gut microbiota produce many chemicals affecting brain function, such as serotonin, dopamine, r-aminobutyric acid, SCFAs, and p-cresol.
“For example, gut microbiota can regulate the hypothalamic-pituitary-adrenal (HPA) axis13, and produce many chemicals affecting brain function (e.g., serotonin, dopamine, r-aminobutyric acid, SCFAs, and p-cresol)14,15.”
From Altered composition and function of intestinal microbiota in autism spectrum disorders: A systematic review (2019) · cites this paper as [15]
Cites
Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits
De Vadder, F., Kovatcheva-Datchary, P., Goncalves, D., Vinera, J., Zitoun, C., Duchampt, A., Bäckhed, F., & Mithieux, G. (2014) · Cell · doi:10.1016/j.cell.2013.12.016 · Cited by 2,200 · see citing works
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New evidences on the altered gut microbiota in autism spectrum disorders
Strati, F., Cavalieri, D., Albanese, D., De Felice, C., Donati, C., Hayek, J., Jousson, O., Leoncini, S., Renzi, D., Calabrò, A., et al. (2017) · Microbiome · doi:10.1186/s40168-017-0242-1 · Cited by 1,040 · see citing works
Liu, F., Li, J., Wu, F., Zheng, H., Peng, Q., & Zhou, H. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0389-6 · Cited by 336 · see citing works
- Authors
- Ray, K.
- Corresponding author
- Ray, Katrina
- ORCID
- Ray, Katrina
- Venue
- Nature Reviews Gastroenterology & Hepatology
- Published
- 2014-01-28
- Volume
- 11
- Issue
- 2
- Pages
- 76-76
- ISSN
- 1759-5045 (ISSN-L)
- 1759-5053
- OpenAlex
- W2069896646
- Cited by
- 12
- References
- 1
- Citations by year
- 2026: 1 · 2024: 2 · 2022: 1 · 2020: 1 · 2019: 1 · 2017: 2 · 2016: 1 · 2015: 1 · 2014: 2
- FWCI
- 0.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Nature Reviews Gastroenterology & Hepatology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolomics and Mass Spectrometry Studies
- Keywords
- gut microbiota metabolites, gut-brain axis, host metabolism, neural circuits, microbial metabolites, host-microbe interactions
- MeSH terms
- Animals, Gluconeogenesis, Intestinal Mucosa, Intestines
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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