Diagnosis and management of chronic constipation in adults

The functional gastrointestinal disorders and the Rome III process

Drossman, D. A. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.03.008 · Cited by 2,416

A Diet Low in FODMAPs Reduces Symptoms of Irritable Bowel Syndrome

Halmos, E. P., Power, V. A., Shepherd, S. J., Gibson, P. R., & Muir, J. G. (2014) · Gastroenterology · doi:10.1053/j.gastro.2013.09.046 · Cited by 1,249

Epidemiology of Constipation in North America: A Systematic Review

Higgins, P., & Johanson, J. (2004) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2004.04114.x · Cited by 1,048

Epidemiology of constipation in children and adults: A systematic review

Mugie, S. M., Benninga, M. A., & Lorenzo, C. D. (2011) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2010.12.010 · Cited by 945

American Gastroenterological Association Technical Review on Constipation

Bharucha, A. E., Pembérton, J. H., & Locke, G. R. (2012) · Gastroenterology · doi:10.1053/j.gastro.2012.10.028 · Cited by 924

Functional anorectal disorders.

Bharucha, A., Wald, A., Enck, P., & Rao, S. S. C. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.11.064 · Cited by 770

Irritable bowel syndrome: a clinical review.

Chey, W., Kurlander, J. E., & Eswaran, S. (2015) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.2015.0954 · Cited by 748

Systematic review: impact of constipation on quality of life in adults and children

Belsey, J., Greenfield, S., Candy, D. C. A., & Geraint, M. (2010) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2010.04273.x · Cited by 559

The brain-gut axis in abdominal pain syndromes.

Mayer, E. A., & Tillisch, K. (2011) · Annual Review of Medicine · doi:10.1146/annurev-med-012309-103958 · Cited by 511

Efficacy and Safety of Traditional Medical Therapies for Chronic Constipation: Systematic Review

Ramkumar, D. P., & Rao, S. S. C. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.40925.x · Cited by 497

Elobixibat Versus Prucalopride in Functional Constipation: A Prospective Comparative Effectiveness Study

Goyal, O., Goyal, M. K., Singh, B., Singh, A., Goyal, P., Mehta, V., Kaushal, S., & Sood, A. (2026) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.70828 · Cited by 3

Defecographic Findings in Patients with Severe Idiopathic Chronic Constipation

Rafiei, R., Bayat, A., Taheri, M., Torabi, Z., Fooladi, L., & Husaini, S. (2017) · Korean Journal of Gastroenterology · doi:10.4166/kjg.2017.70.1.39 · Cited by 3

The Management of Constipation: Current Status and Future Prospects

Maruyama, M., Kamimura, K., Sugita, M., Nakajima, N., Takahashi, Y., Isokawa, O., & Terai, S. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.83467 · Cited by 3

CONSTIPATION

Dunlap, J. J., & Dunlap, B. S. (2021) · Gastroenterology Nursing · doi:10.1097/sga.0000000000000632 · Cited by 3

Cost of Constipation: A New Look With a Focus on New Medications.

Bielefeldt, K. (2022) · PubMed · doi:10.1097/mcg.0000000000001514 · Cited by 1

Neurogenic Bowel Dysfunction

Rodriguez, G. M., Cameron, A. P., & Bush-Arnold, M. (2023) · Springer eBooks · doi:10.1007/978-981-99-1659-7_55 · Cited by 3

Substituted 4-methylcoumarin inhibitors of SLC26A3 (DRA) for treatment of constipation and hyperoxaluria

Ahmadi, M., Gonçalves, L. D. S., Verkman, A. S., Çil, O., & Anderson, M. O. (2024) · RSC Medicinal Chemistry · doi:10.1039/d3md00644a · Cited by 4

Efficacy and mechanism of acupuncture for functional constipation in older adults: study protocol for a randomized controlled trial

Huai, Y., Fan, Q., Dong, Y., Li, X., Hu, J., Liu, L., Chen, Y., & Yin, P. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1341861 · Cited by 4

Examining linaclotide for the treatment of chronic idiopathic constipation

Taclob, J. A., Kalas, M. A., & McCallum, R. W. (2024) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2024.2386160 · Cited by 3

Satisfaction Levels concerning Current Chronic Constipation Treatment Options in Saudi Arabia

Alhossan, A., Alrabiah, Z., Alghadeer, S. M., Wajid, S., Al-Arifi, M. N., & Babelghaith, S. D. (2020) · Gastroenterology Research and Practice · doi:10.1155/2020/6545121 · Cited by 3

Association between 19 Allergens and Chronic Constipation in Adults: NHANES 2005–2006

Xi, Y., Jiao, W.-E., Li, F., Li, H.-D., Gan, L., Deng, Y., & Tao, Z. (2022) · International Archives of Allergy and Immunology · doi:10.1159/000527159 · Cited by 3

Irritable Bowel Syndrome

Vanderberg, R., Lu, A. D., & Hashash, J. G. (2020) · Sex- and Gender-Based Women's Health · doi:10.1007/978-3-030-50695-7_27

Effectiveness and safety of digital rectal stimulation and abdominal massage for neurogenic bowel dysfunction in stroke patients: a randomized controlled trial protocol

Ma, S., Fan, X., He, Y., Li, C., Qu, D., & Man, Y. (2023) · Trials · doi:10.1186/s13063-023-07678-2 · Cited by 2

Artificial Intelligence Model for Time Series Classification: Prediction of Delayed Balloon Expulsion Test Using High‐Resolution Anorectal Manometry Data and Time‐Series Integrated Pressurized Volume

Seo, M., Yoon, K., Jung, K. W., Myung, S., Rao, S. S. C., & Joo, S. (2025) · Neurogastroenterology & Motility · doi:10.1111/nmo.70044 · Cited by 2

Huangqi decoction ameliorated intestinal barrier dysfunction via regulating NF-κB signaling pathway in slow transit constipation model mice

Chen, H., Xiao, G.-Z., Yang, C.-X., Zheng, Y., Lei, M.-Y., Xu, H., Ren, D., Huang, L., He, Q., & Lin, H. (2025) · World Journal of Gastrointestinal Surgery · doi:10.4240/wjgs.v17.i5.106000 · Cited by 2

Efficacy and safety of Shou Hui Tong Bian capsules in the treatment of functional constipation in middle-aged and elderly patients: A multicenter, randomized, controlled trial

Cui, C., Zhao, Q., Wei, F., Wang, Y., Zhao, D., Li, S., Xu, G., Zhang, P., Li, M., Tang, K., et al. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.120039 · Cited by 2

Therapeutic efficacy of a galactoglucan from Pleurotus citrinopileatus in constipation: modulation of aquaporin signaling and intestinal barrier

Gao, Y., Deng, L., Chen, Y., Qin, P., Zhao, Y., Zhao, X., Liu, W., Wang, D., & Zhao, S. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1635487 · Cited by 2

Optimizing diagnosis in obstructed defecation syndrome: A review of imaging modalities

Singh, J. P., Assaie-Ardakany, S., Aleissa, M. A., Al-Shaer, K., Chitragari, G., Drelichman, E. R., Mittal, V. K., & Bhullar, J. S. (2025) · World Journal of Radiology · doi:10.4329/wjr.v17.i7.107459 · Cited by 2

An overview of the current management and emerging therapies of Multiple system atrophy

Sorrentino, C., Baldelli, L., Buonaura, G. C., & Pellecchia, M. T. (2026) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2025.2605711 · Cited by 2

Optimal Single or Combined Parameters for Dyssynergic Defecation on Anorectal Manometry: A Proof-of-Concept Machine Learning Study

Damianos, J., Dilmaghani, S., Matar, A., Halawi, H., Oblizajek, N. R., & Camilleri, M. (2026) · The American Journal of Gastroenterology · doi:10.14309/ajg.0000000000003932 · Cited by 2

Chronic constipation with associated comorbid conditions: a physician survey on clinical perspectives on its diagnosis and management

Kumar, R., Ramakrishnan, S. R., & Kulkarni, A. (2023) · International Journal of Advances in Medicine · doi:10.18203/2349-3933.ijam20232834 · Cited by 2

Nocebo effects and influencing factors in the randomized clinical trials of chronic constipation: A systematic review and meta‐analysis

Yang, J., Guo, J., Yang, X., Chen, J., Bai, T., & Liu, S. (2023) · Neurogastroenterology & Motility · doi:10.1111/nmo.14708 · Cited by 2

Constipation and DIOS: Diagnosis, differential diagnosis, and management

Saikumar, P., Sadauskas, M. K., Izhar, S., Moshiree, B., & Patel, D. R. (2024) · Pediatric Pulmonology · doi:10.1002/ppul.27104 · Cited by 2

Preclinical pharmacokinetic studies and prediction of human PK profiles for Deg-AZM, a clinical-stage new transgelin agonist

Gu, X., Li, X., Tian, W., Zheng, C., Cai, Y., Xu, X. M., Zhao, C., Liu, H., Sun, Y., Luo, Z., et al. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1423175 · Cited by 2

The Associations Between Life's Essential 8 and Diarrhea and Constipation: Results From the 2005–2010 National Health and Nutrition Examination Survey

Yang, X. Y., Ding, S., Guo, J., Peng, S., Duan, Z., & Liu, S. (2024) · Clinical and Translational Gastroenterology · doi:10.14309/ctg.0000000000000801 · Cited by 2

Overall and Regional Colonic Transit Abnormalities in Elderly Patients with Constipation

Yang, D. Y., Lupianez‐Merly, C., Jencks, K. J., Burton, D. D., Ryks, M. D., & Camilleri, M. (2025) · Digestive Diseases and Sciences · doi:10.1007/s10620-024-08833-8 · Cited by 2

Study on the Effect and Mechanism of Weichang'an Pill and Its Extract on Slow Transit Constipation

Wang, N., Lu, X., Gao, P., Zhang, P., Wang, Y., Miao, L., Zhang, H., & Chai, L. (2025) · Neurogastroenterology and Motility · doi:10.1111/nmo.70052 · Cited by 3

Apple Polyphenols and Defecation in Overweight Adults with Constipation – A Randomized Controlled Trial

Sekikawa, T., Li, Y., & Takara, T. (2025) · Journal of Dietary Supplements · doi:10.1080/19390211.2025.2539878 · Cited by 3

Chronic Constipation Management in Adults

Fatmawati, E., Nusi, I. A., Setiawan, P. B., Purbayu, H., Sugihartono, T., Maimunah, U., Kholili, U., Widodo, B., Thamrin, H., Vidyani, A., et al. (2017) · Surabaya International Physiology Seminar (SIPS) · doi:10.5220/0007339703970404 · Cited by 2

Massive Submucosal Ganglia in Colonic Inertia

Naemi, K., Stamos, M. J., & Wu, M. L. (2017) · Archives of Pathology & Laboratory Medicine · doi:10.5858/arpa.2016-0551-oa · Cited by 2

Laxative use and clinical correlates in hospitalized patients with obsessive-compulsive disorder: a retrospective descriptive study

Lai, J., Zhou, W., Lu, Q., Huang, T., Xu, Y., & Hu, S. (2018) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s151396 · Cited by 2

Constipación crónica. Conceptos actuales desde la fisiopatología hasta el tratamiento

García‐Zermeño, K. R. (2021) · Acta gastroenteorológica latinoamericana/Acta gastroenterológica latinoamericana · doi:10.52787/zrrj9030 · Cited by 4

Efficacy and Safety of Maxing Xianchang Su in the Treatment of Functional Constipation: A Randomized Controlled Trial

Li, M., Zhao, L.-J., Ma, L., Zhang, W., Huang, H., Wei, J., Sun, J., Lu, F., & Ji, L.-J. (2021) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2021/3685440 · Cited by 4

Clinical study on the improvement in functional constipation for Panax notoginseng stem and leaf tea combine with panaxnotoginseng fruit and vegetable enzyme and probiotic powder

Hao, S., ZHANG, Y., Ma, W., Li, M., Sisi, T. A. N., Li, J., Li, J., & Lan, L. I. U. (2022) · Food Science and Technology · doi:10.1590/fst.19022 · Cited by 2

A new tool to investigate anorectal disorders in patients with multiple sclerosis: STAR-Q

Tan, E., Turmel, N., Kerdraon, J., Guinet-Lacoste, A., Previnaire, J.-G., Castel-Lacanal, E., Even, A., Chesnel, C., Hentzen, C., & Amarenco, G. (2023) · The French Journal of Urology · doi:10.1016/j.purol.2023.02.006 · Cited by 2

Diagnostic value of balloon expulsion test and anorectal manometry in patients with constipation: a systematic review and meta-analysis

Xu, D., Kuang, M., Liu, Y., & Jiang, H. (2024) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000002743 · Cited by 2

Rectal Perforation Secondary to a Self-Administered Water-Hose Enema: A Case Report and Literature Review

Jabran, H. A. A., Aljawad, H., & Chour, M. (2023) · Cureus · doi:10.7759/cureus.42244 · Cited by 1

Neurogenic Bowel Management in Traumatic Spinal Cord Injury – A Narrative Review

Roy, S. S., Chabungbam, M., & Venkataraman, S. (2024) · Indian Journal of Physical Medicine and Rehabilitation · doi:10.4103/ijpmr.ijpmr_50_23 · Cited by 1

Chronic colonic stasis: some aspects diagnosis and treatment

Гулов, М. К., Nurzoda, Z. M., Ruziboyzoda, K. R., ALI-ZADE, S. G., & Safarov, B. I. (2023) · Экспериментальная и клиническая гастроэнтерология · doi:10.31146/1682-8658-ecg-220-12-120-129 · Cited by 1

The problem of constipation in the practice of an outpatient doctor

Pakhomova, I. G., & Андреевна, Л. А. (2024) · Meditsinskiy sovet = Medical Council · doi:10.21518/ms2024-340 · Cited by 1

Spastic pelvic floor syndrome and puborectalis syndrome: the different stages of the same disease

Xiong, Y., Wang, T., Jiang, D., Chen, Y., Li, W., Tu, M., Qian, Q., Jiang, C., & Liu, W. (2025) · International Journal of Colorectal Disease · doi:10.1007/s00384-025-04834-9 · Cited by 1

Aqueous extract of Solanum americanum Mill. relieves functional constipation by modulating the enteric nervous system and gut micro-ecosystems

Gao, X., Li, Y., Hu, Y., Yang, W., Lei, P., Sheng, J., Tian, Y., Yao, L., & Zhao, Y. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1573516 · Cited by 1

Association of Constipation and Geriatric Depressive Symptoms: Cross-Sectional Analysis Using Baseline Data from the JUSTICE-TOKYO Prospective Cohort Study

Kiko, H., Asaoka, D., Nomura, O., Nomoto, Y., Sugano, K., Matsuno, K., Homma, Y., Nishizaki, Y., Yanagisawa, N., Takeda, T., et al. (2025) · Diagnostics · doi:10.3390/diagnostics15121537 · Cited by 3

Association between youth constipation, emotional/behavioral symptoms, and family quality of life

Chiappini, E. A., Modell, J., Yoo, S., & Domingo, L. S. (2025) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsaf111 · Cited by 1

The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis

Kang, J., Du, Y., Hou, Y., Hao, L., Chen, Z., Xie, H., Zhang, C., & Li, L. (2026) · Phytotherapy Research · doi:10.1002/ptr.70379 · Cited by 2

A Heat-Inactivated Two-Strain Lacticaseibacillus paracasei Fermented Milk as a Postbiotic for Functional Constipation: A Randomized, Double-Blind, Placebo-Controlled Trial

Li, X., Lan, H., Guan, Y., Wang, L., Zhao, W., He, J., Zhao, Z., Li, M., Han, Q., Gong, Y., et al. (2026) · Nutrients · doi:10.3390/nu18132114 · Cited by 1

Rhubarb extract ameliorates slow-transit constipation in rats by modulating gut microbiota and bile acid homeostasis

Du, Y., Zhang, Z., Huang, W., Gao, W., & Li, X. (2026) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2026.122105 · Cited by 1

Laparoscopic-assisted subtotal colectomy cecal-rectal anastomosis for redundant colon-associated slow-transit constipation: a single-center retrospective case series with long-term follow-up

Liu, W.-N., Jiang, Z.-H., Qian-qiu, Z., & Deng, L.-H. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1839442 · Cited by 1

A Protocol-Driven Assessment Promotes a More Accurate Diagnosis of Irritable Bowel Syndrome

Moore, J. S., Gibson, P. R., Perry, R. E., & Burgell, R. (2018) · Gastroenterology Nursing · doi:10.1097/sga.0000000000000349 · Cited by 1

Exertional heat stroke associated with acute liver failure in a young refugee. Implications in the era of social-economic crisis

Politis, D., Baltagiannis, G., Tzampouras, N., Kalambokis, G., Koulouras, V., & Christodoulou, D. K. (2019) · Journal of Gastrointestinal and Liver Diseases · doi:10.15403/jgld-302 · Cited by 1

Gut Stimulatory Effect of Terminalia chebula in Experimental Animal Models

Tandur, V. K., Inamdar, M. N., Alamri, A. S., Alhomrani, M., Alsanie, W. F., Rabbani, S. I., & Asdaq, S. M. B. (2022) · International Journal of Pharmacology · doi:10.3923/ijp.2022.1466.1473 · Cited by 1

Neurogenic Bowel Dysfunction

Rodriguez, G. M., Cameron, A. P., & Bush-Arnold, M. (2022) · Springer eBooks · doi:10.1007/978-981-16-7939-1_55-1 · Cited by 1

The Effect of the Seed of Descurainia Sophia on Functional Constipation in Iranian Women Aged 50-70 Years: A Randomized Controlled Trial

Tabatabaeichehr, M., Mortazavi, H., Pournaghi, S.-J., Kasaian, J., Yaaghoobian, B., Akbari, H., Kheivegi, N., & Alesheikh, P. (2023) · Current Traditional Medicine · doi:10.2174/2215083810666230419091747 · Cited by 1

Hubungan Aktivitas Fisik dan Konsumsi Air dengan Konstipasi pada Mahasiswa Kedokteran Universitas Islam Bandung

Sugiantoro, M. I., Surialaga, S., & Putri, M. (2023) · Jurnal Integrasi Kesehatan & Sains · doi:10.29313/jiks.v5i2.11758 · Cited by 1

EVALUATION OF ANTI-ULCER, LAXATIVE AND ANTI-INFLAMMATORY ACTIVITIES OF TECOMELLA UNDULATA (ROXB.)

Arsalan, M. A., Azhar, I., Muhammad, S., Imam, S., Razaque, G., Jabbar, A., Qadir, A., Khan, N. S., Younis, M., Shahwani, N. A., et al. (2023) · Journal of Population Therapeutics and Clinical Pharmacology · doi:10.53555/jptcp.v30i19.3866 · Cited by 1

Awareness of Constipation and Its Complications Among the General Population of Saudi Arabia

Alshareef, L., Alnafei, K. H., Alibrahim, I. S., Alsharif, A. M., Althubiani, T. M., Mandurah, H. T., & Alsairafi, R. (2024) · Cureus · doi:10.7759/cureus.53030 · Cited by 1

Placebo response to sham electroacupuncture in patients with chronic functional constipation: A secondary analysis

Xiong, Z., Ma, P., Zhang, H., Liu, C., Liu, B., Liu, Z., & Yan, S. (2024) · Neurogastroenterology & Motility · doi:10.1111/nmo.14770 · Cited by 2

DETERMINING THE RELATIONSHIP BETWEEN ADULTS' NUTRITIONAL HABITS AND CONSTIPATION

Yılmaz, H. Ö., & Özgür, M. (2024) · İnönü Üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi · doi:10.33715/inonusaglik.1381544 · Cited by 1

Flaxseed powder and magnesium hydroxide syrup on the intestinal function of patients with acute myocardial infarction in intensive care units.

Suraki, S. A., Bagheri-Nesami, M., Nabati, M., Moosazadeh, M., & Habibi, E. (2024) · PubMed Central · doi:10.22088/cjim.15.2.234 · Cited by 1

The in vivo metabolic pathway of Deg-AZM and in vitro investigations into the contribution of drug metabolizing enzymes and drug transporters in the drug interactions of Deg-AZM, a clinical-stage new transgelin agonist

Gu, X., Li, X., Tian, W., Zheng, C., Cai, Y., Xu, X. M., Zhao, C., Liu, H., Sun, Y., Luo, Z., et al. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1510903 · Cited by 1

Association between body roundness index and constipation using data from NHANES 2005–2010

Guo, C., Peng, Q., Ao, Q., Zheng, Z., & Yu, X. (2025) · Scientific Reports · doi:10.1038/s41598-025-96876-w · Cited by 1

Fluoxetine in Functional Constipation with Somatic Symptom Disorder: Efficacy and Safety from a Propensity Score-Matched Cohort Study

Yang, B., Feng, X., Huang, Q., Li, X., Jiang, X., Fu, W., Zhao, Q., & Zhao, Z. (2025) · Revista Española de Enfermedades Digestivas · doi:10.17235/reed.2025.11434/2025 · Cited by 1

Biofeedback magnetic stimulation improves postoperative bowel dysfunction after rectal cancer surgery

Lin, Y. (2025) · American Journal of Translational Research · doi:10.62347/xbdr6986 · Cited by 1

Inconvenient topic: laxative abuse. review and clinical case

Konovalova, N. V., Стопінчук, О. В., & Крикус, О. Ю. (2020) · Reports of Vinnytsia National Medical University · doi:10.31393/reports-vnmedical-2020-24(4)-28 · Cited by 1

Constipation

Atkinson, N. S. S. (2019) · Springer eBooks · doi:10.1007/978-3-319-75022-4_33 · Cited by 1

Chronic constipation

Sen, A. S. Y., Siah, K. T. H., & Gwee, K. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813037-7.00031-5 · Cited by 1

Anorectal Disorders

Peng, F. B., & Qureshi, W. (2021) · Springer eBooks · doi:10.1007/978-3-030-30192-7_97 · Cited by 1

scRNA-Seq and Network Pharmacology Analysis Reveal SCF/C-kit as the Targeting Mechanism of Qi Lang Formula Relieving ConstipationPreprint

Li, J., Fu, Y., Wang, Y., Zheng, Y., & Li, Y. (2024) · Preprints.org · doi:10.20944/preprints202401.0014.v1 · Cited by 1

Challenging Case in Clinical Practice: Relief from Reported Severe, Chronic Constipation After Implementation of an Elimination Diet

Brand, J. C., & Minich, D. M. (2018) · Alternative and Complementary Therapies · doi:10.1089/act.2018.29190.jcb

Response to lubiprostone in chronic constipation is associated with increased mucus and mucin output: a randomized clinical trial

Tarasiuk, A., Milad, M., Ahmed, S. T., Majewski, M., Wallner, G. T., Fichna, J., Bashashati, M., & Sarosiek, J. (2019) · Journal of Gastrointestinal and Liver Diseases · doi:10.15403/jgld-421

Placebo response rate in patients with chronic constipation

Chen, J., Liu, X., Bai, T., & Hou, X. (2020) · Medicine · doi:10.1097/md.0000000000019020

Muscularis propria detected at colonic biopsy is not a critical value

Arain, H. A., & Wu, M. L. (2020) · Pathology - Research and Practice · doi:10.1016/j.prp.2020.153045

Efficacy and safety of moxibustion for patients with functional constipation

Chen, Y., Xu, M., Hou, T., Wang, L., Feng, X., & Li, Y. (2020) · Medicine · doi:10.1097/md.0000000000020910

Evaluating the efficacy and safety of electro-acupuncture in patients with antipsychotic-related constipation: protocol for a randomized controlled trial

Yu, F.-T., Long, D.-H., Shi, G., Wang, L., Tu, J., Gang, L.-L., Liu, F., Wang, Y., Cui, X., Bao, S., et al. (2021) · Trials · doi:10.1186/s13063-021-05732-5

Background Factors Involved in the Epidemiology of Functional Constipation in the Japanese PopulationPreprint

Yamamoto, S., Ohashi, W., Yamaguchi, Y., Inamoto, S., Koshino, A., Sugiyama, T., Nagao, K., Tamura, Y., Izawa, S., Ebi, M., et al. (2021) · Research Square · doi:10.21203/rs.3.rs-981969/v1

Estreñimiento

Ndam, A. N., Melchior, C., & Ducrotté, P. (2018) · EMC - Tratado de Medicina · doi:10.1016/s1636-5410(18)91413-3

Constipation

Raja, S. M., & Srinivasan, S. (2017) · doi:10.1002/9781119235170.ch9

Clinical efficacy of integral theory–guided laparoscopic integral pelvic floor/ligament repair in the treatment of internal rectal prolapse in females

Yang, Y., Cao, Y., Zhang, Y.-Y., Shi, S.-S., Yang, W.-W., Zhao, N., Lyu, B.-B., Zhang, W., & Dong, W. (2020) · World Journal of Clinical Cases · doi:10.12998/wjcc.v8.i23.5873

Costipazione

Ndam, A. N., Melchior, C., & Ducrotte, P. (2018) · EMC - AKOS - Trattato di Medicina · doi:10.1016/s1634-7358(18)91692-x

Anorectal Disorders

Peng, F. B., & Qureshi, W. (2020) · Springer eBooks · doi:10.1007/978-3-319-90761-1_97-1

Modification of the anastomotic technique in completely laparoscopic resection rectopexy with NOSE — a case report

Mohanty, A. (2022) · Creative Surgery and Oncology · doi:10.24060/2076-3093-2022-12-1-56-60

The interplay between diet, gastrointestinal complaints and gut microbiota: more than a gut feeling?

Rijnaarts, I. (2022) · doi:10.18174/567948

Chimonanthus salicifolius S. Y. Hu Extract improve constipation symptoms and regulate intestinal microbiota in mice

Li, X., & Chen, L. (2022) · Food Science and Technology Research · doi:10.3136/fstr.fstr-d-22-00147

In the Driving Seat with High-Resolution Ano-Rectal Manometry

Nwaezeigwe, M., O’Neill, J., Quinlivan, L., Nolan, L., O’Grady, J., & Buckley, M. J. M. (2024) · Gastrointestinal Disorders · doi:10.3390/gidisord6010007

Some issues of classification and etiopathogenesis of chronic colonic stasis

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